Antimutagenic effects of ethanolic extracts from selected Palestinian medicinal plants

Journal of Ethnopharmacology

Volumn 127, Issue 2, 2010, Pages 319-324

  Khader, M ^a,b   Bresgen, N ^a   Eckl, P M ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

^b ARAB AMERICAN UNIVERSITY   (Palestine)

Author keywords

Cytotoxicity; Eryngium creticum; Genotoxicity; Hepatocytes; Nigella sativa; Teucrium polium

Indexed keywords

ERYNGIUM CRETICUM EXTRACT; METHYLNITRONITROSOGUANIDINE; NIGELLA SATIVA EXTRACT; PLANT EXTRACT; TEUCRIUM POLIUM EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMUTAGENIC ACTIVITY; ARTICLE; CELL PROTECTION; CHROMOSOME; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG MECHANISM; ERYNGIUM CRETICUM; FEMALE; GENOTOXICITY; LIVER CELL CULTURE; MEDICINAL PLANT; NONHUMAN; PALESTINE; RAT; SOLVENT EXTRACTION;

ANIMALS; ANTIMUTAGENIC AGENTS; ARABS; CELLS, CULTURED; ETHANOL; FEMALE; HEPATOCYTES; MIDDLE EAST; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, INBRED F344;

ERYNGIUM CRETICUM; NIGELLA SATIVA; RATTUS; TEUCRIUM POLIUM;

EID: 73749083639     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.11.001     Document Type: Article

References (42)

1. Abu-Irmaileh B.E., and Afifi F.U. Herbal medicine in Jordan with special emphasis on commonly used herbs. Journal of Ethnopharmacology 89 (2003) 193-197
2. Ali-Shtayeh M.S., Yaniv Z., and Mahajna J. Ethnobotanical survey in the Palestinian area: a classification of the healing potential of medicinal plants. Journal of Ethnopharmacology 73 (2000) 221-232
3. Astin J.A., Marie A., Pelletier K.R., Hansen E., and Haskell W.L. A review of the incorporation of complementary and alternative medicine by mainstream physicians. Archives of Internal Medicine 158 (1998) 2303-2310
4. Bourgou S., Ksouri R., Bellila A., Skandrani I., Falleh H., and Marzouk B. Phenolic composition and biological activities of Tunisian Nigella sativa L. shoots and roots. Comptes Rendus Biologies 331 (2008) 48-55
5. Burits M., and Bucar F. Antioxidant activity of Nigella sativa essential oil. Phytotherapy Research 14 (2000) 323-328
6. Eckl P.M., Strom S.C., Michalopoulos G., and Jirtle R.L. Induction of sister chromatid exchanges in cultured adult rat hepatocytes by directly and indirectly acting mutagens/carcinogens. Carcinogenesis 8 (1987) 1077-1083
7. Esteller M., Risques R.A., Toyota M., Capella G., Moreno V., Peinado M.A., Baylin S.B., and Herman J.G. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis. Cancer Research 61 (2001) 4689-4692
8. Everest A., and Ozturk E. Focusing on the ethnobotanical uses of plants in Mersin and Adana provinces (Turkey). Journal of Ethnobiology and Ethnomedicine 1 (2005) 6
9. Feng Q., Torii Y., Uchida K., Nakamura Y., Hara Y., and Osawa T. Black tea polyphenols, theaflavins, prevent cellular DNA damage by inhibiting oxidative stress and suppressing cytochrome P450 1A1 in cell cultures. Journal of Agricultural and Food Chemistry 50 (2002) 213-220
10. Friedman M. Chemistry, biochemistry and dietary role of potato polyphenols. A review. Journal of Agricultural and Food Chemistry 45 (1997) 1523-1540
11. Giulotto E., Mottura A., Giorni R., de Carli L., and Nuzzo F. Frequencies of sister-chromatid exchanges in relation to cell kinetics in lymphocyte cultures. Mutation Research 70 (1980) 343-350
12. Grasl-Kraupp B., Ruttkay-Nedecky B., Koudelka H., Bukowska K., Bursch W., and Schulte-Hermann R. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis and autolytic cell death: a cautionary note. Hepatology 21 (1995) 1465-1468
13. Hajhashemi V., Ghannadi A., and Jafarabadi H. Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. Phytotherapy Research 18 (2004) 195-199
14. Horvathova E., Bonatti S., Abbondandolo A., and Slamenova D. Induction of kintechore positive and negative micronuclei in V79 cells by N-methyl-N′-nitro-N-nitrosoguanidine: the protective effect of the pyridoindole antioxidant stobadine. Mutation Research 395 (1997) 243-247
15. Husgafvel-Pursiainen K. Genotoxicity of environmental tobacco smoke: a review. Mutation Research 567 (2004) 427-445
16. Jakszyn P., and Gonzalez C.A. Nitrosamine and related food intake and gastric and oesophageal cancer risk: a systematic review of the epidemiological evidence. World Journal of Gastroenterology 12 (2006) 4296-4303
17. Joshi B.S., Singh K.L., and Roy R. Complete assignments of 1H and 13C NMR spectra of the pentacyclic triterpene hederagenin from Nigella sativa Linn. Magnetic Resonance in Chemistry 37 (1999) 295-298
18. Ipek E., Zeytinoglu H., Okay S., Tuylu B.A., Kurkcuoglu M., and Can Baser K.H. Genotoxicity and antigenotoxicity of Origanum oil and carvacrol evaluated by Ames Salmonella/microsomal test. Food Chemistry 93 (2005) 551-556
19. Kanter M., Coskun O., and Budancamanak M. Hepatoprotective effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloride-treated rats. World Journal of Gastroenterology 11 (2005) 6684-6688
20. Kartal M., Mitaine-Offer A.C., Abu-Asaker M., Miyamoto T., Calis I., Wagner H., and Lacaille-Dubois M.A. Two new triterpene saponins from Eryngium campestre. Chemical & Pharmaceutical Bulletin 53 (2005) 1318-1320
21. Kaur I.P., and Saini K. Sesamol exhibits antimutagenic activity against oxygen species mediated mutagenicity. Mutation Research 470 (2000) 71-76
22. Khader M., Eckl P., and Bresgen M.N. Effects of aqueous extracts of medicinal plants on MNNG-treated rat hepatocytes in primary cultures. Journal of Ethnopharmacology 112 (2007) 199-202
23. Khader M., Bresgen N., and Eckl P.M. In vitro toxicological properties of thymoquinone. Food and Chemical Toxicology 47 (2009) 129-133
24. Liu J., Liu Y., Bullock P., and Klaassen C.D. Suppression of liver cytochrome P450 by α-hederin: relevance to hepatoprotection. Toxicology and Applied Pharmacology 134 (1995) 124-131
25. Ljubuncic P., Azaizeh H., Portnaya I., Cogan U., Said O., Saleh K.A., and Bomzon A. Antioxidant activity and cytotoxicity of eight plants used in traditional Arab medicine in Israel. Journal of Ethnopharmacology 99 (2005) 43-47
26. Müller M., Wilder S., Bannasch D., Israeli D., Lehlbach K., Li-Weber M., Friedman S.L., Galle P.R., Stremmel W., Oren M., and Krammer P.H. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. Journal of Experimental Medicine 188 (1998) 2033-2045
27. Neri M., Ugolini D., Bonassi S., Fucic A., Holland N., Knudsen L.E., Sram R.J., Ceppi M., Bocchini V., and Merlo D.F. Children's exposure to environmental pollutants and biomarkers of genetic damage. II. Results of a comprehensive literature search and meta-analysis. Mutation Research 612 (2006) 14-39
28. Oberhammer F.A., Pavelka M., Sharma S., Tiefenbacher R., Purchio A.F., Bursch W., and Schulte-Hermann R. Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1. Proceedings of the National Academy of Sciences 89 (1992) 5408-5412
29. Ong E.S. Extraction methods and chemical standardisation of botanicals and herbal preparations. Journal of Chromatography B 812 (2004) 23-33
30. Park K.Y., Jung G.O., Choi J., Lee K.T., and Park H.J. Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana. Archives of Pharmacal Research 25 (2002) 320-324
31. Said O., Khalil K., Fulder S., and Azaizeh H. Ethnopharmacological survey of medicinal herbs in Israel, the Golan Heights and the West Bank region. Journal of Ethnopharmacology 83 (2002) 251-265
32. Salim E.I., and Fukushima S. Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carinogenesis. Nutrition and Cancer 45 (2003) 195-202
33. Sayer J.M., Yagi H., Wood A.W., Conney A.H., and Jerina D.M. Extremely facile reaction between the ultimate carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide and ellagic acid. Journal of the American Chemical Society 104 (1982) 5562-5564
34. Sezik E., Yesilada E., Honda G., Takaishi Y., Takeda Y., and Tanaka T. Traditional medicine in Turkey X. Folk medicine in Central Anatolia. Journal of Ethnopharmacology 75 (2001) 95-115
35. Strzelecka M., Bzowska M., Koziel J., Szuba B., Dubiel O., Riviera Nunez D., Heinrich M., and Bereta J. Anti-inflammatory effects of extracts from some traditional Mediterranean diet plants. Journal of Physiology and Pharmacology 56 Suppl. 1 (2005) 139-156
36. Suboh S.M., Bilto Y.Y., and Aburjai T.A. Protective effects of selected medicinal plants against protein degradation, lipid peroxidation and deformability loss of oxidatively stressed human erythrocytes. Phytotherapy Research 18 (2004) 280-284
37. Tariq M., Ageel A.M., al-Yahya M.A., Mossa J.S., and al-Said M.S. Anti-inflammatory activity of Teucrium polium. International Journal of tissue Reactions 11 (1989) 185-188
38. Wang M., Tsao R., Zhang S., Dong Z., Yang R., Gong J., and Pei Y. antioxidant activity, mutagenicity/anti-mutagenicity, and clastogenicity/anti-clastogenicity of lutein from marigold flowers. Food and Chemical Toxicology 44 (2006) 1522-1529
39. Wasfi L.A., Bashir A.A., Abdalla A.A., and Andri M.H. Some pharmacological studies on Teucrium mascatense: effect on glucose homeostasis in normal and streptozotocin diabetic rats and antimicrobial activity. Arab Gulf Journal of Scientific Research 10 (1992) 145-157
40. World Health Organization. Traditional medicine-growing needs and potential. WHO Policy Perspectives on Medicines 2 (2002) 1-6
41. Yawar A. Spirituality in medicine: what is to be done?. Journal of the Royal Society of Medicine 94 (2001) 529-533
42. Yen G.-C., and Chen H.-Y. Antioxidant activity of various tea extracts in relation to their antimutagenicity. Journal of Agricultural and Food Chemistry 43 (1995) 27-32