메뉴 건너뛰기




Volumn 11, Issue 42, 2005, Pages 6684-6688

Hepatoprotective effects of Nigella sativa L and Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloride-treated rats

Author keywords

Antioxidant enzymes; CCl4; Lipid peroxidation; Nigella sativa L; Rat; Urtica dioica L

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; BETA CAROTENE; CARBON TETRACHLORIDE; CERULOPLASMIN; GLUTATHIONE; LIVER ENZYME; LIVER PROTECTIVE AGENT; MALONALDEHYDE; NIGELLA SATIVA EXTRACT; PHENYLENEDIAMINE; RETINOL; SODIUM CHLORIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; URTICA DIOICA EXTRACT;

EID: 30444452089     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i42.6684     Document Type: Article
Times cited : (240)

References (40)
  • 2
    • 0028177267 scopus 로고
    • Possible role of cell redox state on collagen metabolism in carbon tetrachloride-induced cirrhosis as evidenced by adenosine administration to rats
    • Hernandez-Munoz R, Diaz-Munoz M, Chagoya de Sanchez V. Possible role of cell redox state on collagen metabolism in carbon tetrachloride-induced cirrhosis as evidenced by adenosine administration to rats. Biochem Biophys Acta 1994; 1200: 93-99
    • (1994) Biochem Biophys Acta , vol.1200 , pp. 93-99
    • Hernandez-Munoz, R.1    Diaz-Munoz, M.2    Chagoya de Sanchez, V.3
  • 3
    • 0032531047 scopus 로고    scopus 로고
    • Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride
    • Muriel P. Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride. Biochemical Pharmacology 1998; 56: 773-779
    • (1998) Biochemical Pharmacology , vol.56 , pp. 773-779
    • Muriel, P.1
  • 4
    • 0026670128 scopus 로고
    • Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis
    • Parola M, Leonarduzzi G, Biasi F, Albano E, Biocca ME, Poli G, Dianzani MU. Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis. Hepatology 1992; 16: 1014-1021
    • (1992) Hepatology , vol.16 , pp. 1014-1021
    • Parola, M.1    Leonarduzzi, G.2    Biasi, F.3    Albano, E.4    Biocca, M.E.5    Poli, G.6    Dianzani, M.U.7
  • 5
    • 0025157647 scopus 로고
    • The pathology of hepatic iron overload: A free radical-mediated process?
    • Bacon BR, Britton RS. The pathology of hepatic iron overload: a free radical-mediated process? Hepatology 1990; 11: 127-137
    • (1990) Hepatology , vol.11 , pp. 127-137
    • Bacon, B.R.1    Britton, R.S.2
  • 6
    • 0029869179 scopus 로고    scopus 로고
    • On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis
    • Parola M, Leonarduzzi G, Robino G, Albano E, Poli G, Dianzani MU. On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis. Free Radic Biol Med 1996; 20: 351-359
    • (1996) Free Radic Biol Med , vol.20 , pp. 351-359
    • Parola, M.1    Leonarduzzi, G.2    Robino, G.3    Albano, E.4    Poli, G.5    Dianzani, M.U.6
  • 7
    • 0026717172 scopus 로고
    • Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: Association of lipid peroxidation with liver fibrogenesis
    • Kamimura S, Gaal K, Britton RS, Bacon BR, Triadafilopoulos G, Tsukamoto H. Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: association of lipid peroxidation with liver fibrogenesis. Hepatology 1992; 16: 448-453
    • (1992) Hepatology , vol.16 , pp. 448-453
    • Kamimura, S.1    Gaal, K.2    Britton, R.S.3    Bacon, B.R.4    Triadafilopoulos, G.5    Tsukamoto, H.6
  • 8
    • 0030829836 scopus 로고    scopus 로고
    • Biochemical effect of antioxidants on lipids and liver function in experimentally-induced liver damage
    • Halim AB, El-Ahmady O, Hassab-Allah S, Abdel-Galil F, Hafez Y, Darwish A. Biochemical effect of antioxidants on lipids and liver function in experimentally-induced liver damage. Ann Clin Biochem 1997; 34 (Pt 6): 656-663
    • (1997) Ann Clin Biochem , vol.34 , Issue.PART 6 , pp. 656-663
    • Halim, A.B.1    El-Ahmady, O.2    Hassab-Allah, S.3    Abdel-Galil, F.4    Hafez, Y.5    Darwish, A.6
  • 11
    • 0027290046 scopus 로고
    • The respiratory effects of the volatile oil of the black seed (Nigella saliva) in guinea-pigs: Elucidation of the mechanism(s) of action
    • El Tahir KE, Ashour MM, al-Harbi MM. The respiratory effects of the volatile oil of the black seed (Nigella saliva) in guinea-pigs: elucidation of the mechanism(s) of action. Gen Pharmacol 1993; 24: 1115-1122
    • (1993) Gen Pharmacol , vol.24 , pp. 1115-1122
    • El Tahir, K.E.1    Ashour, M.M.2    al-Harbi, M.M.3
  • 12
    • 0038713648 scopus 로고
    • The black seed (Nigella sativa) and immunity: Its effect on human T cell subset
    • El-Kadi A, Kandil O. The black seed (Nigella sativa) and immunity: its effect on human T cell subset. Fed Proc 1987; 46: 1222
    • (1987) Fed Proc , vol.46 , pp. 1222
    • El-Kadi, A.1    Kandil, O.2
  • 13
    • 0028852880 scopus 로고
    • Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation
    • Houghton PJ, Zarka R, de las Heras B, Hoult JR. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med 1995; 61: 33-36
    • (1995) Planta Med , vol.61 , pp. 33-36
    • Houghton, P.J.1    Zarka, R.2    de las Heras, B.3    Hoult, J.R.4
  • 14
    • 0031863041 scopus 로고    scopus 로고
    • Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in rats
    • discussion 93-5
    • El Daly ES. Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in rats. J Pharm Belg 1998; 53: 87-93; discussion 93-5
    • (1998) J Pharm Belg , vol.53 , pp. 87-93
    • El Daly, E.S.1
  • 15
    • 0032923512 scopus 로고    scopus 로고
    • Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB
    • Riehemann K, Behnke B, Schulze-Osthoff K. Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB. FEBS Lett 1999; 442: 89-94
    • (1999) FEBS Lett , vol.442 , pp. 89-94
    • Riehemann, K.1    Behnke, B.2    Schulze-Osthoff, K.3
  • 16
    • 0024430237 scopus 로고
    • Biologically active compounds from the aqueous extract of Urtica dioica
    • Wagner H, Willer F, Kreher B. Biologically active compounds from the aqueous extract of Urtica dioica. Planta Med 1989; 55: 452-454
    • (1989) Planta Med , vol.55 , pp. 452-454
    • Wagner, H.1    Willer, F.2    Kreher, B.3
  • 17
    • 0025142672 scopus 로고
    • Malondialdehyde determination as index of lipid peroxidation
    • Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 1990; 186: 421-431
    • (1990) Methods Enzymol , vol.186 , pp. 421-431
    • Draper, H.H.1    Hadley, M.2
  • 18
    • 73649194769 scopus 로고
    • Improved metod fot the determination of blood glutathione
    • Buetler E, Dubon O, Kelly BM. Improved metod fot the determination of blood glutathione. J Lab Clin Med 1963; 61: 882-888
    • (1963) J Lab Clin Med , vol.61 , pp. 882-888
    • Buetler, E.1    Dubon, O.2    Kelly, B.M.3
  • 19
    • 0014883924 scopus 로고
    • Measurement of human serum ceruloplasmin by its p-phenylenediamine oxidase activity
    • Sunderman FW Jr, Nomoto S. Measurement of human serum ceruloplasmin by its p-phenylenediamine oxidase activity. Clin Chem 1970; 16: 903-910
    • (1970) Clin Chem , vol.16 , pp. 903-910
    • Sunderman Jr., F.W.1    Nomoto, S.2
  • 20
    • 0011266776 scopus 로고
    • Method for the determination of vjitamin E (total tocopherols) in serum
    • Martinek RG. Method for the determination of vjitamin E (total tocopherols) in serum. Clin Chem 1964;10:1078-1086
    • (1964) Clin Chem , vol.10 , pp. 1078-1086
    • Martinek, R.G.1
  • 21
    • 0018369625 scopus 로고
    • Selected methods for the determination of ascorbic acid in animal cells, tissues, and fluids
    • Omaye ST, Turnbull JD, Sauberlich HE.Selected methods for the determination of ascorbic acid in animal cells, tissues, and fluids. Methods Enzymol 1979; 62: 3-11
    • (1979) Methods Enzymol , vol.62 , pp. 3-11
    • Omaye, S.T.1    Turnbull, J.D.2    Sauberlich, H.E.3
  • 22
    • 0025653734 scopus 로고
    • A simple and cheap methods for measuring serum vitamin A in cattle using only a spectrophotometer
    • Suzuki J, Katoh N. A simple and cheap methods for measuring serum vitamin A in cattle using only a spectrophotometer. Nippon Juigaku Zasshi 1990; 52: 1281-1283
    • (1990) Nippon Juigaku Zasshi , vol.52 , pp. 1281-1283
    • Suzuki, J.1    Katoh, N.2
  • 23
    • 0025907763 scopus 로고
    • Animal models of fulminant hepatic failure
    • Terblanche J, Hickman R. Animal models of fulminant hepatic failure. Dig Dis Sci 1991; 36: 770-774
    • (1991) Dig Dis Sci , vol.36 , pp. 770-774
    • Terblanche, J.1    Hickman, R.2
  • 24
    • 0027226140 scopus 로고
    • Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells
    • Parola M, Pinzani M, Casini A, Albano E, Poli G, Gentilini A, Gentilini P, Dianzani MU. Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. Biochem Biophys Res Commun 1993; 194: 1044-1050
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 1044-1050
    • Parola, M.1    Pinzani, M.2    Casini, A.3    Albano, E.4    Poli, G.5    Gentilini, A.6    Gentilini, P.7    Dianzani, M.U.8
  • 25
    • 0014856083 scopus 로고
    • Drugs and the liver
    • Sherlock S. [Drugs and the liver] G Clin Med 1970; 51: 753-759
    • (1970) G Clin Med , vol.51 , pp. 753-759
    • Sherlock, S.1
  • 26
    • 0024439390 scopus 로고
    • Cytochrome P-450, reductive metabolism, and cell injury
    • De Groot H, Sies H. Cytochrome P-450, reductive metabolism, and cell injury. Drug Metab Rev 1989; 20: 275-284
    • (1989) Drug Metab Rev , vol.20 , pp. 275-284
    • De Groot, H.1    Sies, H.2
  • 27
    • 0029171522 scopus 로고
    • The influence of "selenium organicum" upon the hepatic function of carbon tetrachloride poisoned rats
    • Ianas O, Olinescu R, Badescu I, Simionescu L, Popovici D. The influence of "selenium organicum" upon the hepatic function of carbon tetrachloride poisoned rats. Rom J Intern Med 1995; 33: 113-120
    • (1995) Rom J Intern Med , vol.33 , pp. 113-120
    • Ianas, O.1    Olinescu, R.2    Badescu, I.3    Simionescu, L.4    Popovici, D.5
  • 28
    • 0009609961 scopus 로고
    • Antioxidant drugs and colchicine in the treatment of alcoholic liver disease
    • Arroyo, V., Bosch, J., Rodes, J., eds. First ed. Barcelone Masson
    • Seitz HK, Pöschl G. Antioxidant drugs and colchicine in the treatment of alcoholic liver disease. In: Arroyo, V., Bosch, J., Rodes, J., eds. Treatments in Hepatology. First ed. Barcelone Masson 1995; 271-276
    • (1995) Treatments in Hepatology , pp. 271-276
    • Seitz, H.K.1    Pöschl, G.2
  • 29
    • 0035146058 scopus 로고    scopus 로고
    • Clinical studies with silymarin: Fibrosis progression is the end point
    • Schuppan D, Hahn EG. Clinical studies with silymarin: fibrosis progression is the end point. Hepatology 2001; 33: 483-484
    • (2001) Hepatology , vol.33 , pp. 483-484
    • Schuppan, D.1    Hahn, E.G.2
  • 30
    • 0034066205 scopus 로고    scopus 로고
    • Sho-saiko-to: Japanese herbal medicine for protection against hepatic fibrosis and carcinoma
    • Shimizu I. Sho-saiko-to: Japanese herbal medicine for protection against hepatic fibrosis and carcinoma. J Gastroenterol Hepatol 2000; 15 Suppl: D84-90
    • (2000) J Gastroenterol Hepatol , vol.15 , Issue.SUPPL.
    • Shimizu, I.1
  • 31
    • 0344643075 scopus 로고    scopus 로고
    • Antioxidative effect of chitosan on chronic carbon tetrachloride induced hepatic injury in rats
    • Jeon TI, Hwang SG, Park NG, Jung YR, Shin SI, Choi SD, Park DK. Antioxidative effect of chitosan on chronic carbon tetrachloride induced hepatic injury in rats. Toxicology 2003; 187: 67-73
    • (2003) Toxicology , vol.187 , pp. 67-73
    • Jeon, T.I.1    Hwang, S.G.2    Park, N.G.3    Jung, Y.R.4    Shin, S.I.5    Choi, S.D.6    Park, D.K.7
  • 32
    • 0021645190 scopus 로고
    • Zinc: What is its role in biology?
    • Williams RJ. Zinc: what is its role in biology? Endeavour 1984; 8: 65-70
    • (1984) Endeavour , vol.8 , pp. 65-70
    • Williams, R.J.1
  • 33
    • 0025239795 scopus 로고
    • The physiological role of zinc as an antioxidant
    • Bray TM, Bettger WJ. The physiological role of zinc as an antioxidant. Free Radic Biol Med 1990; 8: 281-291
    • (1990) Free Radic Biol Med , vol.8 , pp. 281-291
    • Bray, T.M.1    Bettger, W.J.2
  • 34
    • 0032584004 scopus 로고    scopus 로고
    • Hepatoprotective activity of thymoquinone in isolated rat hepatocytes
    • Daba MH, Abdel-Rahman MS. Hepatoprotective activity of thymoquinone in isolated rat hepatocytes. Toxicol Lett 1998; 95: 23-29
    • (1998) Toxicol Lett , vol.95 , pp. 23-29
    • Daba, M.H.1    Abdel-Rahman, M.S.2
  • 36
    • 17144460933 scopus 로고    scopus 로고
    • The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats
    • Turkdogan MK, Ozbek H, Yener Z, Tuncer I, Uygan I, Ceylan E. The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats. Phytother Res 2003; 17: 942-946
    • (2003) Phytother Res , vol.17 , pp. 942-946
    • Turkdogan, M.K.1    Ozbek, H.2    Yener, Z.3    Tuncer, I.4    Uygan, I.5    Ceylan, E.6
  • 37
    • 0035259357 scopus 로고    scopus 로고
    • The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: New hopes
    • Turkdogan MK, Agaoglu Z, Yener Z, Sekeroglu R, Akkan HA, Avci ME. The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: new hopes. Dtsch Tierarztl Wochenschr 2001; 108: 71-73
    • (2001) Dtsch Tierarztl Wochenschr , vol.108 , pp. 71-73
    • Turkdogan, M.K.1    Agaoglu, Z.2    Yener, Z.3    Sekeroglu, R.4    Akkan, H.A.5    Avci, M.E.6
  • 38
    • 0033955610 scopus 로고    scopus 로고
    • Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract
    • Konrad L, Muller HH, Lenz C, Laubinger H, Aumuller G, Lichius JJ. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Med 2000; 66: 44-47
    • (2000) Planta Med , vol.66 , pp. 44-47
    • Konrad, L.1    Muller, H.H.2    Lenz, C.3    Laubinger, H.4    Aumuller, G.5    Lichius, J.J.6
  • 39
    • 0038207948 scopus 로고    scopus 로고
    • Modulatory effect of Urtica dioica L. (Urticaceae) leaf extract on biotransformation enzyme systems, antioxidant enzymes, lactate dehydrogenase and lipid peroxidation in mice
    • Ozen T, Korkmaz H. Modulatory effect of Urtica dioica L. (Urticaceae) leaf extract on biotransformation enzyme systems, antioxidant enzymes, lactate dehydrogenase and lipid peroxidation in mice. Phytomedicine 2003; 10: 405-415
    • (2003) Phytomedicine , vol.10 , pp. 405-415
    • Ozen, T.1    Korkmaz, H.2
  • 40
    • 0242317355 scopus 로고    scopus 로고
    • Effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in CCl4-treated rats
    • Kanter M, Meral I, Dede S, Gunduz H, Cemek M, Ozbek H, Uygan I. Effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in CCl4-treated rats. J Vet Med A Physiol Pathol Clin Med 2003; 50: 264-268
    • (2003) J Vet Med A Physiol Pathol Clin Med , vol.50 , pp. 264-268
    • Kanter, M.1    Meral, I.2    Dede, S.3    Gunduz, H.4    Cemek, M.5    Ozbek, H.6    Uygan, I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.