The challenges of the analysis of basic compounds by high performance liquid chromatography: Some possible approaches for improved separations

Journal of Chromatography A

Volumn 1217, Issue 6, 2010, Pages 858-880

  McCalley, David V ^a  

^a UNIVERSITY OF THE WEST OF ENGLAND   (United Kingdom)

Author keywords

Basic compounds; HILIC; HPLC; Reversed phase; Stationary phases

Indexed keywords

ALTERNATIVE METHODS; BASIC COMPOUNDS; HYDROPHILIC INTERACTION CHROMATOGRAPHY; MOBILE PHASE CONDITIONS; PEAK SHAPES; REVERSED PHASE; REVERSED-PHASE CHROMATOGRAPHY; SILANOL GROUPS; STATIONARY PHASIS;

CHROMATOGRAPHIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; SEPARATION;

COLUMN CHROMATOGRAPHY;

ACECAINIDE; AMITRIPTYLINE; AMPHETAMINE; BERBERINE; CODEINE; DIPHENHYDRAMINE; METOPROLOL; NORTRIPTYLINE; OXACILLIN; PROCAINAMIDE; PROPRANOLOL; PROTRIPTYLINE; PYRIDINE; QUININE; SILANOL; SILICON DIOXIDE;

DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; PH; PRIORITY JOURNAL; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVIEW; SEPARATION TECHNIQUE; TEMPERATURE;

ANIONS; CATIONS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; HYDROGEN-ION CONCENTRATION; HYDROPHOBICITY; SILICON DIOXIDE; TEMPERATURE;

EID: 73649141021     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.11.068     Document Type: Review

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