A new approach to the determination of column overload characteristics in reversed-phase liquid chromatography

Journal of Chromatography A

Volumn 1216, Issue 12, 2009, Pages 2474-2482

  Dai, Jun ^a   Carr, Peter W ^b   McCalley, David V ^c  

^a BRISTOL MYERS SQUIBB   (United States)

^b University of Minnesota   (United States)

^c UNIVERSITY OF THE WEST OF ENGLAND   (United Kingdom)

Author keywords

Column sample loading capacity; Langmuirian non linear chromatography; Limiting plate count; Overload

Indexed keywords

ANALYTES; CHROMATOGRAPHIC PROCESS; COLUMN LENGTHS; COLUMN SAMPLE LOADING CAPACITY; COMPLEX INTERACTIONS; CONSTANT CONDITIONS; LANGMUIRIAN NON-LINEAR CHROMATOGRAPHY; LIMITING PLATE COUNT; LINEAR ISOTHERMS; MOBILE PHASIS; MOBILE-PHASE COMPOSITIONS; NEW APPROACHES; NON-LINEAR; NONPOLAR SOLUTES; OVERLOAD; PEAK SHAPES; PEAK WIDTHS; PRACTICAL METHODS; PRECISE MEASUREMENTS; REVERSED-PHASE LIQUID CHROMATOGRAPHIES; RIGOROUS MODELS; SAMPLE LOADS; TWO PARAMETERS;

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; FLOW RATE; IONIZATION OF LIQUIDS; LIQUID CHROMATOGRAPHY; LIQUIDS; LOADING;

COLUMN CHROMATOGRAPHY;

ACCURACY; ARTICLE; FLOW RATE; ISOTHERM; MATHEMATICAL MODEL; NONLINEAR SYSTEM; PLATE COUNT; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SIGNAL NOISE RATIO;

ALGORITHMS; CHROMATOGRAPHY, LIQUID; MODELS, CHEMICAL; MODELS, STATISTICAL; NORMAL DISTRIBUTION;

EID: 60649114859     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.01.036     Document Type: Article

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