-
1
-
-
0141688283
-
Adoptive-cell-transfer therapy for the treatment of patients with cancer
-
Dudley ME, Rosenberg SA. Adoptive-cell-transfer therapy for the treatment of patients with cancer. Nat Rev Cancer 2003;3:666-75.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 666-675
-
-
Dudley, M.E.1
Rosenberg, S.A.2
-
2
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan RA, Dudley ME, Wunderlich JR, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006;314:126-9.
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
-
4
-
-
0034278156
-
Lentiviral vectors: Excellent tools for experimental gene transfer and promising candidates for gene therapy
-
Vigna E, Naldini L. Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy. J Gene Med 2000;2:308-16.
-
(2000)
J Gene Med
, vol.2
, pp. 308-316
-
-
Vigna, E.1
Naldini, L.2
-
5
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
Follenzi A, Ailles LE, Bakovic S, Geuna M, Naldini L. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat Genet 2000;25:217-22.
-
(2000)
Nat Genet
, vol.25
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
6
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey R, Donello JE, Trono D, Hope TJ. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol 1999;73:2886-92.
-
(1999)
J Virol
, vol.73
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
-
7
-
-
0037133212
-
Transgenesis by lentiviral vectors: Lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos
-
Pfeifer A, Ikawa M, Dayn Y, Verma IM. Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos. Proc Natl Acad Sci U S A 2002;99:2140-5.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2140-2145
-
-
Pfeifer, A.1
Ikawa, M.2
Dayn, Y.3
Verma, I.M.4
-
8
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini L, Blomer U, Gallay P, et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996;272:263-7.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
-
9
-
-
33744940000
-
+ T cells: Importance for the therapeutic effectiveness of cell transfer immunotherapy
-
+ T cells: importance for the therapeutic effectiveness of cell transfer immunotherapy. J Immunol 2006;176:7726-35.
-
(2006)
J Immunol
, vol.176
, pp. 7726-7735
-
-
Huang, J.1
Kerstann, K.W.2
Ahmadzadeh, M.3
-
11
-
-
27744450650
-
Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy
-
Zhou J, Shen X, Huang J, Hodes RJ, Rosenberg SA, Robbins PF. Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy. J Immunol 2005;175:7046-52.
-
(2005)
J Immunol
, vol.175
, pp. 7046-7052
-
-
Zhou, J.1
Shen, X.2
Huang, J.3
Hodes, R.J.4
Rosenberg, S.A.5
Robbins, P.F.6
-
12
-
-
10344261422
-
Cutting edge: Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
-
Robbins PF, Dudley ME, Wunderlich J, et al. Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy. J Immunol 2004;173:7125-30.
-
(2004)
J Immunol
, vol.173
, pp. 7125-7130
-
-
Robbins, P.F.1
Dudley, M.E.2
Wunderlich, J.3
-
13
-
-
0036884742
-
Progressive differentiation and selection of the fittest in the immune response
-
Lanzavecchia A, Sallusto F. Progressive differentiation and selection of the fittest in the immune response. Nat Rev Immunol 2002;2:982-7.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 982-987
-
-
Lanzavecchia, A.1
Sallusto, F.2
-
14
-
-
15244351083
-
Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
-
Amendola M, Venneri MA, Biffi A, Vigna E, Naldini L. Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. Nat Biotechnol 2005;23:108-16.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 108-116
-
-
Amendola, M.1
Venneri, M.A.2
Biffi, A.3
Vigna, E.4
Naldini, L.5
-
15
-
-
47249100641
-
Human TCR that incorporate CD3ζ induce highly preferred pairing between TCRα and β chains following gene transfer
-
Sebestyen Z, Schooten E, Sals T, et al. Human TCR that incorporate CD3ζ induce highly preferred pairing between TCRα and β chains following gene transfer. J Immunol 2008;180:7736-46.
-
(2008)
J Immunol
, vol.180
, pp. 7736-7746
-
-
Sebestyen, Z.1
Schooten, E.2
Sals, T.3
-
16
-
-
0036784658
-
Large and dissimilar repertoire of Melan-A/MART-1-specific CTL in metastatic lesions and blood of a melanoma patient
-
Mandruzzato S, Rossi E, Bernardi F, et al. Large and dissimilar repertoire of Melan-A/MART-1-specific CTL in metastatic lesions and blood of a melanoma patient. J Immunol 2002;169:4017-24.
-
(2002)
J Immunol
, vol.169
, pp. 4017-4024
-
-
Mandruzzato, S.1
Rossi, E.2
Bernardi, F.3
-
17
-
-
65549086161
-
Interferon-α counteracts the angiogenic switch and reduces tumor cell proliferation in a spontaneous model of prostatic cancer
-
Persano L, Moserle L, Esposito G, et al. Interferon-α counteracts the angiogenic switch and reduces tumor cell proliferation in a spontaneous model of prostatic cancer. Carcinogenesis 2009;30:851-60.
-
(2009)
Carcinogenesis
, vol.30
, pp. 851-860
-
-
Persano, L.1
Moserle, L.2
Esposito, G.3
-
18
-
-
0032723133
-
DNA-based vaccination against tumors expressing the P1A antigen
-
Rosato A, Milan G, Collavo D, Zanovello P. DNA-based vaccination against tumors expressing the P1A antigen. Methods 1999;19:187-90.
-
(1999)
Methods
, vol.19
, pp. 187-190
-
-
Rosato, A.1
Milan, G.2
Collavo, D.3
Zanovello, P.4
-
19
-
-
0028988146
-
Role of anti-LFA-1 and anti-ICAM-1 combined MAb treatment in the rejection of tumors induced by Moloney murine sarcoma virus (M-MSV)
-
Rosato A, Mandruzzato S, Bronte V, et al. Role of anti-LFA-1 and anti-ICAM-1 combined MAb treatment in the rejection of tumors induced by Moloney murine sarcoma virus (M-MSV). Int J Cancer 1995;61:355-62.
-
(1995)
Int J Cancer
, vol.61
, pp. 355-362
-
-
Rosato, A.1
Mandruzzato, S.2
Bronte, V.3
-
20
-
-
0036827965
-
Gene transfer in ovarian cancer cells: A comparison between retroviral and lentiviral vectors
-
Indraccolo S, Habeler W, Tisato V, et al. Gene transfer in ovarian cancer cells: a comparison between retroviral and lentiviral vectors. Cancer Res 2002;62: 6099-107.
-
(2002)
Cancer Res
, vol.62
, pp. 6099-6107
-
-
Indraccolo, S.1
Habeler, W.2
Tisato, V.3
-
21
-
-
22144447521
-
Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes
-
Tsuji T, Yasukawa M, Matsuzaki J, et al. Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes. Blood 2005;106:470-6.
-
(2005)
Blood
, vol.106
, pp. 470-476
-
-
Tsuji, T.1
Yasukawa, M.2
Matsuzaki, J.3
-
22
-
-
0037442013
-
Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR α β genes into primary human T lymphocytes
-
Schaft N, Willemsen RA, de Vries J, et al. Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR α β genes into primary human T lymphocytes. J Immunol 2003; 170:2186-94.
-
(2003)
J Immunol
, vol.170
, pp. 2186-2194
-
-
Schaft, N.1
Willemsen, R.A.2
de Vries, J.3
-
23
-
-
0037128179
-
Thymic selection generates a large T cell pool recognizing a self-peptide in humans
-
Zippelius A, Pittet MJ, Batard P, et al. Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med 2002;195:485-94.
-
(2002)
J Exp Med
, vol.195
, pp. 485-494
-
-
Zippelius, A.1
Pittet, M.J.2
Batard, P.3
-
24
-
-
9144239842
-
Potentiation of tumor eradication by adoptive immunotherapy with T-cell receptor gene-transduced T-helper type 1 cells
-
Chamoto K, Tsuji T, Funamoto H, et al. Potentiation of tumor eradication by adoptive immunotherapy with T-cell receptor gene-transduced T-helper type 1 cells. Cancer Res 2004;64:386-90.
-
(2004)
Cancer Res
, vol.64
, pp. 386-390
-
-
Chamoto, K.1
Tsuji, T.2
Funamoto, H.3
-
25
-
-
53149126134
-
TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation
-
de Witte MA, Bendle GM, van den Boom MD, et al. TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation. J Immunol 2008;181: 2563-71.
-
(2008)
J Immunol
, vol.181
, pp. 2563-2571
-
-
de Witte, M.A.1
Bendle, G.M.2
van den Boom, M.D.3
-
26
-
-
33745859204
-
Targeting self-antigens through allogeneic TCR gene transfer
-
de Witte MA, Coccoris M, Wolkers MC, et al. Targeting self-antigens through allogeneic TCR gene transfer. Blood 2006;108:870-7.
-
(2006)
Blood
, vol.108
, pp. 870-877
-
-
de Witte, M.A.1
Coccoris, M.2
Wolkers, M.C.3
-
27
-
-
33745823524
-
Generation of T cell help through a MHC class I-restricted TCR
-
Kessels HW, Schepers K, van den Boom MD, Topham DJ, Schumacher TN. Generation of T cell help through a MHC class I-restricted TCR. J Immunol 2006;177:976-82.
-
(2006)
J Immunol
, vol.177
, pp. 976-982
-
-
Kessels, H.W.1
Schepers, K.2
van den Boom, M.D.3
Topham, D.J.4
Schumacher, T.N.5
-
28
-
-
0034769412
-
Immunotherapy through TCR gene transfer
-
Kessels HW, Wolkers MC, van den Boom MD, van der Valk MA, Schumacher TN. Immunotherapy through TCR gene transfer. Nat Immunol 2001;2:957-61.
-
(2001)
Nat Immunol
, vol.2
, pp. 957-961
-
-
Kessels, H.W.1
Wolkers, M.C.2
van den Boom, M.D.3
van der Valk, M.A.4
Schumacher, T.N.5
-
29
-
-
20344400625
-
A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection
-
Morris EC, Tsallios A, Bendle GM, Xue SA, Stauss HJ. A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection. Proc Natl Acad Sci U S A 2005;102:7934-9.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7934-7939
-
-
Morris, E.C.1
Tsallios, A.2
Bendle, G.M.3
Xue, S.A.4
Stauss, H.J.5
-
30
-
-
40749116082
-
T-cell receptor gene therapy of established tumors in a murine melanoma model
-
Abad JD, Wrzensinski C, Overwijk W, et al. T-cell receptor gene therapy of established tumors in a murine melanoma model. J Immunother 2008;31:1-6.
-
(2008)
J Immunother
, vol.31
, pp. 1-6
-
-
Abad, J.D.1
Wrzensinski, C.2
Overwijk, W.3
-
31
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
Dudley ME, Wunderlich JR, Yang JC, et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol 2005;23:2346-57.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
-
33
-
-
70149114880
-
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
-
Johnson LA, Morgan RA, Dudley ME, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009;114:535-46.
-
(2009)
Blood
, vol.114
, pp. 535-546
-
-
Johnson, L.A.1
Morgan, R.A.2
Dudley, M.E.3
-
34
-
-
29244483981
-
Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction: Implications for loss of transgene expression
-
Lamers CH, Gratama JW, Pouw NM, et al. Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction: implications for loss of transgene expression. Hum Gene Ther 2005;16: 1452-62.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 1452-1462
-
-
Lamers, C.H.1
Gratama, J.W.2
Pouw, N.M.3
-
36
-
-
41149097574
-
Adoptive cell transfer: A clinical path to effective cancer immunotherapy
-
Rosenberg SA, Restifo NP, Yang JC, Morgan RA, Dudley ME. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer 2008; 8:299-308.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
Morgan, R.A.4
Dudley, M.E.5
-
37
-
-
65249101260
-
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
-
Montini E, Cesana D, Schmidt M, et al. The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. J Clin Invest 2009; 119:964-75.
-
(2009)
J Clin Invest
, vol.119
, pp. 964-975
-
-
Montini, E.1
Cesana, D.2
Schmidt, M.3
-
38
-
-
58149380748
-
Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins
-
Frecha C, Costa C, Negre D, et al. Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins. Blood 2008;112:4843-52.
-
(2008)
Blood
, vol.112
, pp. 4843-4852
-
-
Frecha, C.1
Costa, C.2
Negre, D.3
-
40
-
-
15244358572
-
Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes
-
Pinthus JH, Waks T, Malina V, et al. Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes. J Clin Invest 2004;114:1774-81.
-
(2004)
J Clin Invest
, vol.114
, pp. 1774-1781
-
-
Pinthus, J.H.1
Waks, T.2
Malina, V.3
-
41
-
-
27144435476
-
Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR
-
Cohen CJ, Zheng Z, Bray R, et al. Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR. J Immunol 2005;175:5799-808.
-
(2005)
J Immunol
, vol.175
, pp. 5799-5808
-
-
Cohen, C.J.1
Zheng, Z.2
Bray, R.3
-
42
-
-
19944434233
-
+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR
-
+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR. Immunity 2005;22:117-29.
-
(2005)
Immunity
, vol.22
, pp. 117-129
-
-
Kuball, J.1
Schmitz, F.W.2
Voss, R.H.3
-
43
-
-
0042834246
-
High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens
-
Morgan RA, Dudley ME, Yu YY, et al. High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens. J Immunol 2003;171: 3287-95.
-
(2003)
J Immunol
, vol.171
, pp. 3287-3295
-
-
Morgan, R.A.1
Dudley, M.E.2
Yu, Y.Y.3
-
45
-
-
15444371764
-
Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines
-
Zhao Y, Zheng Z, Robbins PF, Khong HT, Rosenberg SA, Morgan RA. Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines. J Immunol 2005;174:4415-23.
-
(2005)
J Immunol
, vol.174
, pp. 4415-4423
-
-
Zhao, Y.1
Zheng, Z.2
Robbins, P.F.3
Khong, H.T.4
Rosenberg, S.A.5
Morgan, R.A.6
-
46
-
-
0032856752
-
A new era of cancer immunotherapy: Converting theory to performance
-
Rosenberg SA. A new era of cancer immunotherapy: converting theory to performance. CA Cancer J Clin 1999;49:70-3, 65.
-
(1999)
CA Cancer J Clin
, vol.49
, Issue.70-73
, pp. 65
-
-
Rosenberg, S.A.1
-
48
-
-
0029608719
-
Targeting p53 as a general tumor antigen
-
Theobald M, Biggs J, Dittmer D, Levine AJ, Sherman LA. Targeting p53 as a general tumor antigen. Proc Natl Acad Sci U S A 1995;92:11993-7.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11993-11997
-
-
Theobald, M.1
Biggs, J.2
Dittmer, D.3
Levine, A.J.4
Sherman, L.A.5
-
49
-
-
0033151591
-
The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes
-
Vonderheide RH, Hahn WC, Schultze JL, Nadler LM. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity 1999;10:673-9.
-
(1999)
Immunity
, vol.10
, pp. 673-679
-
-
Vonderheide, R.H.1
Hahn, W.C.2
Schultze, J.L.3
Nadler, L.M.4
|