-
1
-
-
33847314184
-
Angiogenesis meets immunology: Cytokine gene therapy of cancer
-
Minuzzo,S. et al. (2007) Angiogenesis meets immunology: Cytokine gene therapy of cancer. Mol. Aspects Med., 28, 59-86.
-
(2007)
Mol. Aspects Med
, vol.28
, pp. 59-86
-
-
Minuzzo, S.1
-
2
-
-
0023160237
-
Inhibition of angiogenesis by interferons: Effects on tumor- and lymphocyte-induced vascular responses
-
Sidky,Y.A. et al. (1987) Inhibition of angiogenesis by interferons: Effects on tumor- and lymphocyte-induced vascular responses. Cancer Res., 47, 5155-5161.
-
(1987)
Cancer Res
, vol.47
, pp. 5155-5161
-
-
Sidky, Y.A.1
-
3
-
-
0032929390
-
Interferon (IFN)-beta gene transfer into TS/A adenocarcinoma cells and comparison with IFN-alpha: Differential effects on tumorigenicity and host response
-
Rozera,C. et al. (1999) Interferon (IFN)-beta gene transfer into TS/A adenocarcinoma cells and comparison with IFN-alpha: Differential effects on tumorigenicity and host response. Am. J. Pathol., 154, 1211-1222.
-
(1999)
Am. J. Pathol
, vol.154
, pp. 1211-1222
-
-
Rozera, C.1
-
4
-
-
0036289066
-
Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells
-
Indraccolo,S. et al. (2002) Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells. Gene Ther., 9, 867-878.
-
(2002)
Gene Ther
, vol.9
, pp. 867-878
-
-
Indraccolo, S.1
-
5
-
-
0033848253
-
Inhibition of angiogenesis and vascular tumor growth by interferon-producing cells: A gene therapy approach
-
Albini,A. et al. (2000) Inhibition of angiogenesis and vascular tumor growth by interferon-producing cells: A gene therapy approach. Am. J. Pathol., 156, 1381-1393.
-
(2000)
Am. J. Pathol
, vol.156
, pp. 1381-1393
-
-
Albini, A.1
-
6
-
-
0029075603
-
Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas
-
Singh,R.K. et al. (1995) Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc. Natl Acad. Sci. USA, 92, 4562-4566.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 4562-4566
-
-
Singh, R.K.1
-
7
-
-
0037454239
-
Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis
-
von Marschall,Z. et al. (2003) Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis. J. Natl Cancer Inst., 95, 437-448.
-
(2003)
J. Natl Cancer Inst
, vol.95
, pp. 437-448
-
-
von Marschall, Z.1
-
8
-
-
0026756731
-
Downregulation of interleukin 8 gene expression in human fibroblasts: Unique mechanism of transcriptional inhibition by interferon
-
Oliveira,I.C. et al. (1992) Downregulation of interleukin 8 gene expression in human fibroblasts: Unique mechanism of transcriptional inhibition by interferon. Proc. Natl Acad. Sci. USA, 89, 9049-9053.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 9049-9053
-
-
Oliveira, I.C.1
-
9
-
-
33846255059
-
Identification of genes selectively regulated by IFNs in endothelial cells
-
Indraccolo,S. et al. (2007) Identification of genes selectively regulated by IFNs in endothelial cells. J. Immunol., 178, 1122-1135.
-
(2007)
J. Immunol
, vol.178
, pp. 1122-1135
-
-
Indraccolo, S.1
-
10
-
-
0037108881
-
Inhibition of growth and metastasis of orthotopic human prostate cancer in athymic mice by combination therapy with pegylated interferon-alpha-2b and docetaxel
-
Huang,S.F. et al. (2002) Inhibition of growth and metastasis of orthotopic human prostate cancer in athymic mice by combination therapy with pegylated interferon-alpha-2b and docetaxel. Cancer Res., 62, 5720-5726.
-
(2002)
Cancer Res
, vol.62
, pp. 5720-5726
-
-
Huang, S.F.1
-
11
-
-
0033557916
-
Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineered to produce interferon-beta
-
Dong,Z. et al. (1999) Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineered to produce interferon-beta. Cancer Res., 59, 872-879.
-
(1999)
Cancer Res
, vol.59
, pp. 872-879
-
-
Dong, Z.1
-
12
-
-
0036718371
-
Tumor-infiltrating macrophages are involved in suppressing growth and metastasis of human prostate cancer cells by INF-beta gene therapy in nude mice
-
Zhang,F. et al. (2002) Tumor-infiltrating macrophages are involved in suppressing growth and metastasis of human prostate cancer cells by INF-beta gene therapy in nude mice. Clin. Cancer Res., 8, 2942-2951.
-
(2002)
Clin. Cancer Res
, vol.8
, pp. 2942-2951
-
-
Zhang, F.1
-
13
-
-
0034904471
-
Adenovirus-mediated interferon-beta gene therapy suppresses growth and metastasis of human prostate cancer in nude mice
-
Cao,G. et al. (2001) Adenovirus-mediated interferon-beta gene therapy suppresses growth and metastasis of human prostate cancer in nude mice. Cancer Gene Ther., 8, 497-505.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 497-505
-
-
Cao, G.1
-
14
-
-
0034062135
-
Interferon-gamma and its functional receptors overexpression in benign prostatic hyperplasia and prostatic carcinoma: Parallelism with c-myc and p53 expression
-
Royuela,M. et al. (2000) Interferon-gamma and its functional receptors overexpression in benign prostatic hyperplasia and prostatic carcinoma: Parallelism with c-myc and p53 expression. Eur. Cytokine Netw., 11, 119-127.
-
(2000)
Eur. Cytokine Netw
, vol.11
, pp. 119-127
-
-
Royuela, M.1
-
15
-
-
0028911462
-
Prostate cancer in a transgenic mouse
-
Greenberg,N.M. et al. (1995) Prostate cancer in a transgenic mouse. Proc. Natl Acad. Sci. USA, 92, 3439-3443.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 3439-3443
-
-
Greenberg, N.M.1
-
16
-
-
0035866779
-
Angiogenesis and prostate cancer: Identification of a molecular progression switch
-
Huss,W.J. et al. (2001) Angiogenesis and prostate cancer: identification of a molecular progression switch. Cancer Res., 61, 2736-2743.
-
(2001)
Cancer Res
, vol.61
, pp. 2736-2743
-
-
Huss, W.J.1
-
17
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers,G. et al. (2003) Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer, 3, 401-410.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
-
18
-
-
33746161915
-
Study of microvessel density and the expression of the angiogenic factors VEGF, bFGF and the receptors Flt-1 and FLK-1 in benign, premalignant and malignant prostate tissues
-
Pallares,J. et al. (2006) Study of microvessel density and the expression of the angiogenic factors VEGF, bFGF and the receptors Flt-1 and FLK-1 in benign, premalignant and malignant prostate tissues. Histol. Histopathol., 21, 857-865.
-
(2006)
Histol. Histopathol
, vol.21
, pp. 857-865
-
-
Pallares, J.1
-
19
-
-
5044239254
-
Angiogenesis and VEGF expression in pre-invasive lesions of the human breast
-
Viacava,P. et al. (2004) Angiogenesis and VEGF expression in pre-invasive lesions of the human breast. J. Pathol., 204, 140-146.
-
(2004)
J. Pathol
, vol.204
, pp. 140-146
-
-
Viacava, P.1
-
20
-
-
0346014623
-
Gene therapy of prostate cancer with the soluble vascular endothelial growth factor receptor Flk1
-
Becker,C.M. et al. (2002) Gene therapy of prostate cancer with the soluble vascular endothelial growth factor receptor Flk1. Cancer Biol. Ther., 1, 548-553.
-
(2002)
Cancer Biol. Ther
, vol.1
, pp. 548-553
-
-
Becker, C.M.1
-
21
-
-
1942503022
-
SU5416 selectively impairs angiogenesis to induce prostate cancer-specific apoptosis
-
Huss,W.J. et al. (2003) SU5416 selectively impairs angiogenesis to induce prostate cancer-specific apoptosis. Mol. Cancer Ther., 2 611-616.
-
(2003)
Mol. Cancer Ther
, vol.2
, pp. 611-616
-
-
Huss, W.J.1
-
22
-
-
34250843284
-
Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model
-
Isayeva,T. et al. (2007) Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model. Cancer Res., 67, 5789-5797.
-
(2007)
Cancer Res
, vol.67
, pp. 5789-5797
-
-
Isayeva, T.1
-
23
-
-
23844499688
-
Interferon-alpha gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition
-
Indraccolo,S. et al. (2005) Interferon-alpha gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition. Hum. Gene Ther., 16, 957-970.
-
(2005)
Hum. Gene Ther
, vol.16
, pp. 957-970
-
-
Indraccolo, S.1
-
24
-
-
0036827965
-
Gene transfer in ovarian cancer cells: A comparison between retroviral and lentiviral vectors
-
Indraccolo,S. et al. (2002) Gene transfer in ovarian cancer cells: a comparison between retroviral and lentiviral vectors. Cancer Res. 62, 6099-6107.
-
(2002)
Cancer Res
, vol.62
, pp. 6099-6107
-
-
Indraccolo, S.1
-
25
-
-
0036841930
-
Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases
-
Lubeseder-Martellato,C. et al. (2002) Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am. J. Pathol., 161, 1749-1759.
-
(2002)
Am. J. Pathol
, vol.161
, pp. 1749-1759
-
-
Lubeseder-Martellato, C.1
-
26
-
-
0033461161
-
The central interactive region of human MxA GTPase is involved in GTPase activation and interaction with viral target structures
-
Flohr,F. et al. (1999) The central interactive region of human MxA GTPase is involved in GTPase activation and interaction with viral target structures. FEBS Lett., 463, 24-28.
-
(1999)
FEBS Lett
, vol.463
, pp. 24-28
-
-
Flohr, F.1
-
27
-
-
0031762769
-
The murine homolog of the HIN 200 family, Ifi 204, is constitutively expressed in myeloid cells and selectively induced in the monocyte/macrophage lineage
-
Gariglio,M. et al. (1998) The murine homolog of the HIN 200 family, Ifi 204, is constitutively expressed in myeloid cells and selectively induced in the monocyte/macrophage lineage. J. Leukoc. Biol., 64, 608-614.
-
(1998)
J. Leukoc. Biol
, vol.64
, pp. 608-614
-
-
Gariglio, M.1
-
28
-
-
33744815944
-
Gene therapy of ovarian cancer with IFN-alpha-producing fibroblasts: Comparison of constitutive and inducible vectors
-
Indraccolo,S. et al. (2006) Gene therapy of ovarian cancer with IFN-alpha-producing fibroblasts: Comparison of constitutive and inducible vectors. Gene Ther., 13, 953-965.
-
(2006)
Gene Ther
, vol.13
, pp. 953-965
-
-
Indraccolo, S.1
-
29
-
-
0038376002
-
Molecular regulation of vessel maturation
-
Jain,R.K. (2003) Molecular regulation of vessel maturation. Nat. Med. 9, 685-693.
-
(2003)
Nat. Med
, vol.9
, pp. 685-693
-
-
Jain, R.K.1
-
30
-
-
40349087128
-
Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression
-
Sun,A. et al. (2008) Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression. Prostate, 68, 453-461.
-
(2008)
Prostate
, vol.68
, pp. 453-461
-
-
Sun, A.1
-
31
-
-
13544272733
-
Cyclin D2 induces proliferation of cardiac myocytes and represses hypertrophy
-
Busk,P.K. et al. (2005) Cyclin D2 induces proliferation of cardiac myocytes and represses hypertrophy. Exp. Cell Res., 304, 149-161.
-
(2005)
Exp. Cell Res
, vol.304
, pp. 149-161
-
-
Busk, P.K.1
-
32
-
-
0020955866
-
Interferon induction of fibroblast proteins with guanylate binding activity
-
Cheng,Y.S. et al. (1983) Interferon induction of fibroblast proteins with guanylate binding activity. J. Biol. Chem., 258 7746-7750.
-
(1983)
J. Biol. Chem
, vol.258
, pp. 7746-7750
-
-
Cheng, Y.S.1
-
33
-
-
12144289725
-
IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat
-
Nakaji,M. et al. (2004) IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat. Carcinogenesis, 25, 389-397.
-
(2004)
Carcinogenesis
, vol.25
, pp. 389-397
-
-
Nakaji, M.1
-
34
-
-
52949148222
-
Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis
-
De Palma,M. et al. (2008) Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer Cell, 14, 299-311.
-
(2008)
Cancer Cell
, vol.14
, pp. 299-311
-
-
De Palma, M.1
-
35
-
-
34250903656
-
Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculature
-
Dickson,P.V. et al. (2007) Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculature. Mol. Cancer Res., 5, 531-542.
-
(2007)
Mol. Cancer Res
, vol.5
, pp. 531-542
-
-
Dickson, P.V.1
-
36
-
-
0030005902
-
Antiangiogenic therapy of transgenic mice impairs de novo tumor growth
-
Parangi,S. et al. (1996) Antiangiogenic therapy of transgenic mice impairs de novo tumor growth. Proc. Natl Acad. Sci. USA, 93, 2002-2007.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 2002-2007
-
-
Parangi, S.1
-
37
-
-
0037220643
-
Differential expression of specific FGF ligand and receptor isoforms during angiogenesis associated with prostate cancer progression
-
Huss,W.J. et al. (2003) Differential expression of specific FGF ligand and receptor isoforms during angiogenesis associated with prostate cancer progression. Prostate, 54, 8-16.
-
(2003)
Prostate
, vol.54
, pp. 8-16
-
-
Huss, W.J.1
-
38
-
-
0141731322
-
Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer
-
Polnaszek,N. et al. (2003) Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer. Cancer Res., 63, 5754-5760.
-
(2003)
Cancer Res
, vol.63
, pp. 5754-5760
-
-
Polnaszek, N.1
-
39
-
-
0742306871
-
The interferon-inducible p200 family of proteins: A perspective on their roles in cell cycle regulation and differentiation
-
Asefa,B. et al. (2004) The interferon-inducible p200 family of proteins: A perspective on their roles in cell cycle regulation and differentiation. Blood Cells Mol. Dis., 32, 155-167.
-
(2004)
Blood Cells Mol. Dis
, vol.32
, pp. 155-167
-
-
Asefa, B.1
-
40
-
-
33747587608
-
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all
-
Gil,J. et al. (2006) Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all. Nat. Rev. Mol. Cell Biol., 7, 667-677.
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 667-677
-
-
Gil, J.1
-
41
-
-
0030609969
-
IFNalpha induces the expression of the cyclin-dependent kinase inhibitor p21 in human prostate cancer cells
-
Hobeika,A.C. et al. (1997) IFNalpha induces the expression of the cyclin-dependent kinase inhibitor p21 in human prostate cancer cells. Oncogene, 14, 1165-1170.
-
(1997)
Oncogene
, vol.14
, pp. 1165-1170
-
-
Hobeika, A.C.1
-
42
-
-
0031992604
-
Is tissue mass regulated by vascular endothelial cells? Prostate as the first evidence
-
Folkman,J. (1998) Is tissue mass regulated by vascular endothelial cells? Prostate as the first evidence. Endocrinology, 139, 441-442.
-
(1998)
Endocrinology
, vol.139
, pp. 441-442
-
-
Folkman, J.1
-
43
-
-
0033215242
-
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
-
Olumi,A.F. et al. (1999) Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res., 59, 5002-5011.
-
(1999)
Cancer Res
, vol.59
, pp. 5002-5011
-
-
Olumi, A.F.1
-
44
-
-
0036005886
-
Interferon-alpha in tumor immunity and immunotherapy
-
Belardelli,F. et al. (2002) Interferon-alpha in tumor immunity and immunotherapy. Cytokine Growth Factor Rev., 13, 119-134.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 119-134
-
-
Belardelli, F.1
-
45
-
-
51649095449
-
Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy
-
Naschberger,E. et al. (2008) Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy. Int. J. Cancer, 123, 2120-2129.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 2120-2129
-
-
Naschberger, E.1
-
46
-
-
33748801748
-
Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis
-
Naschberger,E. et al. (2006) Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis. Am. J. Pathol., 169, 1088-1099.
-
(2006)
Am. J. Pathol
, vol.169
, pp. 1088-1099
-
-
Naschberger, E.1
-
47
-
-
28444482348
-
Human guanylate binding protein-1 (hGBP-1) characterizes and establishes a non-angiogenic endothelial cell activation phenotype in inflammatory diseases
-
Naschberger,E. et al. (2005) Human guanylate binding protein-1 (hGBP-1) characterizes and establishes a non-angiogenic endothelial cell activation phenotype in inflammatory diseases. Adv. Enzyme Regul., 45, 215-227.
-
(2005)
Adv. Enzyme Regul
, vol.45
, pp. 215-227
-
-
Naschberger, E.1
-
48
-
-
2342568371
-
Nuclear factor-kappaB motif and interferon-alpha- stimulated response element co-operate in the activation of guanylate-binding protein-1 expression by inflammatory cytokines in endothelial cells
-
Naschberger,E. et al. (2004) Nuclear factor-kappaB motif and interferon-alpha- stimulated response element co-operate in the activation of guanylate-binding protein-1 expression by inflammatory cytokines in endothelial cells. Biochem. J., 379, 409-420.
-
(2004)
Biochem. J
, vol.379
, pp. 409-420
-
-
Naschberger, E.1
-
49
-
-
0042525961
-
The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression
-
Guenzi,E. et al. (2003) The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression. EMBO J., 22, 3772-3782.
-
(2003)
EMBO J
, vol.22
, pp. 3772-3782
-
-
Guenzi, E.1
-
50
-
-
27644506613
-
Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
-
Varambally,S. et al. (2005) Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer Cell, 8, 393-406.
-
(2005)
Cancer Cell
, vol.8
, pp. 393-406
-
-
Varambally, S.1
-
51
-
-
33646940750
-
Molecular biology of prostate-cancer pathogenesis
-
Shand,R.L. et al. (2006) Molecular biology of prostate-cancer pathogenesis. Curr. Opin. Urol., 16, 123-131.
-
(2006)
Curr. Opin. Urol
, vol.16
, pp. 123-131
-
-
Shand, R.L.1
|