-
1
-
-
0036558025
-
The SOCS box: A tale of destruction and degradation
-
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ 2002 The SOCS box: a tale of destruction and degradation. Trends Biochem Sci 27:235-241
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 235-241
-
-
Kile, B.T.1
Schulman, B.A.2
Alexander, W.S.3
Nicola, N.A.4
Martin, H.M.5
Hilton, D.J.6
-
2
-
-
33947510306
-
Ankyrin repeat and suppressors of cytokine signaling box protein Asb-9 targets creatine kinase B for degradation
-
Debrincat MA, Zhang JG, Willson TA, Silke J, Connolly LM, Simpson RJ, Alexander WS, Nicola NA, Kile BT, Hilton DJ 2007 Ankyrin repeat and suppressors of cytokine signaling box protein Asb-9 targets creatine kinase B for degradation. J Biol Chem 282:4728-4737
-
(2007)
J Biol Chem
, vol.282
, pp. 4728-4737
-
-
Debrincat, M.A.1
Zhang, J.G.2
Willson, T.A.3
Silke, J.4
Connolly, L.M.5
Simpson, R.J.6
Alexander, W.S.7
Nicola, N.A.8
Kile, B.T.9
Hilton, D.J.10
-
3
-
-
4644257119
-
Asb6, an adipocyte-specific ankyrin andSOCSbox protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex
-
Wilcox A, Katsanakis KD, Bheda F, Pillay TS 2004 Asb6, an adipocyte-specific ankyrin andSOCSbox protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex. J Biol Chem 279:38881-38888
-
(2004)
J Biol Chem
, vol.279
, pp. 38881-38888
-
-
Wilcox, A.1
Katsanakis, K.D.2
Bheda, F.3
Pillay, T.S.4
-
4
-
-
28844473943
-
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes
-
Kohroki J, Nishiyama T, Nakamura T, Masuho Y 2005 ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes. FEBS Lett 579:6796-6802
-
(2005)
FEBS Lett
, vol.579
, pp. 6796-6802
-
-
Kohroki, J.1
Nishiyama, T.2
Nakamura, T.3
Masuho, Y.4
-
5
-
-
0034722724
-
Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4
-
. Kile BT, Viney EM, Willson TA, Brodnicki TC, Cancilla MR, Herlihy AS, Croker BA, Baca M, Nicola NA, Hilton DJ, Alexander WS 2000 Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4. Gene 258:31-41
-
(2000)
Gene
, vol.258
, pp. 31-41
-
-
Kile, B.T.1
Viney, E.M.2
Willson, T.A.3
Brodnicki, T.C.4
Cancilla, M.R.5
Herlihy, A.S.6
Croker, B.A.7
Baca, M.8
Nicola, N.A.9
Hilton, D.J.10
Alexander, W.S.11
-
6
-
-
20444379578
-
Arcuate nucleus transcriptome profiling identifies ankyrin repeat and SOCS box-containing protein 4 as a gene regulated by fasting in central nervous system feeding circuits
-
Li JY, Kuick R, Thompson RC, Misek DE, Lai YM, Liu YQ, Chai BX, Hanash SM, Gantz I 2005 Arcuate nucleus transcriptome profiling identifies ankyrin repeat and SOCS box-containing protein 4 as a gene regulated by fasting in central nervous system feeding circuits. J Neuroendocrinol 17:394-404
-
(2005)
J Neuroendocrinol
, vol.17
, pp. 394-404
-
-
Li, J.Y.1
Kuick, R.2
Thompson, R.C.3
Misek, D.E.4
Lai, Y.M.5
Liu, Y.Q.6
Chai, B.X.7
Hanash, S.M.8
Gantz, I.9
-
8
-
-
37549014516
-
Neuronal control of energy homeostasis
-
Gao Q, Horvath TL 2008 Neuronal control of energy homeostasis. FEBS Lett 582:132-141
-
(2008)
FEBS Lett
, vol.582
, pp. 132-141
-
-
Gao, Q.1
Horvath, T.L.2
-
9
-
-
0030928715
-
Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
-
Cheung CC, Clifton DK, Steiner RA 1997 Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus. Endocrinology 138:4489-4492
-
(1997)
Endocrinology
, vol.138
, pp. 4489-4492
-
-
Cheung, C.C.1
Clifton, D.K.2
Steiner, R.A.3
-
10
-
-
0030729210
-
Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
-
Thornton JE, Cheung CC, Clifton DK, Steiner RA 1997 Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice. Endocrinology 138:5063-5066
-
(1997)
Endocrinology
, vol.138
, pp. 5063-5066
-
-
Thornton, J.E.1
Cheung, C.C.2
Clifton, D.K.3
Steiner, R.A.4
-
11
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS 1999 Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:68-100
-
(1999)
Endocr Rev
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
Kalra, P.S.6
-
12
-
-
16244381143
-
Identification of neuronal enhancer of the proopiomelanorcortin gene by transgenic mouse analysis and phylogenetic footprinting
-
de Souza FS, Santanelo AM, Bumaschny V, Avale ME, Smart JL, Low MJ, Rubinstein M 2005 Identification of neuronal enhancer of the proopiomelanorcortin gene by transgenic mouse analysis and phylogenetic footprinting. Mol Cell Biol 25:3076-3086
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3076-3086
-
-
de Souza, F.S.1
Santanelo, A.M.2
Bumaschny, V.3
Avale, M.E.4
Smart, J.L.5
Low, M.J.6
Rubinstein, M.7
-
13
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F 1997 Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
14
-
-
50449085374
-
Effect of des-acyl ghrelin on adiposity and glucose metabolism
-
Zhang W, Chai B, Li JY, Wang H, Mulholland MW 2008 Effect of des-acyl ghrelin on adiposity and glucose metabolism. Endocrinology 149:4710-4716
-
(2008)
Endocrinology
, vol.149
, pp. 4710-4716
-
-
Zhang, W.1
Chai, B.2
Li, J.Y.3
Wang, H.4
Mulholland, M.W.5
-
15
-
-
0003698235
-
The rat brain in stereotaxic coordinates
-
4th ed, Australia: Academic Press
-
Paxinos G, Watson C 1998 The rat brain in stereotaxic coordinates. 4th ed. Bowen Hills, Australia: Academic Press
-
(1998)
Bowen Hills
-
-
Paxinos, G.1
Watson, C.2
-
17
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
19
-
-
0031888157
-
-
Mizuno TM, Kleopoulos SP, Bergen HT, Roberts JL, Priest CA, Mobbs CV 1998 Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin. Diabetes [Erratum (1998) 47:696] 47: 294-297
-
Mizuno TM, Kleopoulos SP, Bergen HT, Roberts JL, Priest CA, Mobbs CV 1998 Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin. Diabetes [Erratum (1998) 47:696] 47: 294-297
-
-
-
-
20
-
-
0020172822
-
Effect of chronic food restriction on energy balance, thermogenic capacity, and brown-adiposetissue activity in the rat
-
Rothwell NJ, Stock MJ 1982 Effect of chronic food restriction on energy balance, thermogenic capacity, and brown-adiposetissue activity in the rat. Biosci Rep 2:543-549
-
(1982)
Biosci Rep
, vol.2
, pp. 543-549
-
-
Rothwell, N.J.1
Stock, M.J.2
-
21
-
-
0027305031
-
Resting oxygen consumption in rats during food restriction, starvation and refeeding
-
Munch IC, Markussen NH, Oritsland NA 1993 Resting oxygen consumption in rats during food restriction, starvation and refeeding. Acta Physiol Scand 148:335-340
-
(1993)
Acta Physiol Scand
, vol.148
, pp. 335-340
-
-
Munch, I.C.1
Markussen, N.H.2
Oritsland, N.A.3
-
23
-
-
17844401704
-
Anatomy and regulation of the central melanocortin system
-
Cone RD 2005 Anatomy and regulation of the central melanocortin system. Nat Neurosci 8:571-578
-
(2005)
Nat Neurosci
, vol.8
, pp. 571-578
-
-
Cone, R.D.1
-
24
-
-
2342427535
-
The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis
-
Ellacott KL, Cone RD 2004 The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis. Rec Prog Horm Res 59:395-408
-
(2004)
Rec Prog Horm Res
, vol.59
, pp. 395-408
-
-
Ellacott, K.L.1
Cone, R.D.2
-
25
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD 1997 Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385:165-168
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
26
-
-
33645089926
-
A role for β-melanocyte-stimulating hormone in human body-weight regulation
-
Biebermann H, Castañeda TR, van Landeghem F, von Deimling A, Escher F, Brabant G, Hebebrand J, Hinney A, Tschöp MH, Grüters A, Krude H 2006 A role for β-melanocyte-stimulating hormone in human body-weight regulation. Cell Metab 3:141-146
-
(2006)
Cell Metab
, vol.3
, pp. 141-146
-
-
Biebermann, H.1
Castañeda, T.R.2
van Landeghem, F.3
von Deimling, A.4
Escher, F.5
Brabant, G.6
Hebebrand, J.7
Hinney, A.8
Tschöp, M.H.9
Grüters, A.10
Krude, H.11
-
27
-
-
33645048441
-
APOMC variant implicates β-melanocyte-stimulating hormone in the control of human energy balance
-
Lee YS, Challis BG, Thompson DA, Yeo GS, Keogh JM, Madonna ME, Wraight V, Sims M, Vatin V, Meyre D, Shield J, Burren C, Ibrahim Z, Cheetham T, Swift P, Blackwood A, Hung CC, Wareham NJ, Froguel P, Millhauser GL, O'Rahilly S, Farooqi IS 2006 APOMC variant implicates β-melanocyte-stimulating hormone in the control of human energy balance. Cell Metab 3:135-140
-
(2006)
Cell Metab
, vol.3
, pp. 135-140
-
-
Lee, Y.S.1
Challis, B.G.2
Thompson, D.A.3
Yeo, G.S.4
Keogh, J.M.5
Madonna, M.E.6
Wraight, V.7
Sims, M.8
Vatin, V.9
Meyre, D.10
Shield, J.11
Burren, C.12
Ibrahim, Z.13
Cheetham, T.14
Swift, P.15
Blackwood, A.16
Hung, C.C.17
Wareham, N.J.18
Froguel, P.19
Millhauser, G.L.20
O'Rahilly, S.21
Farooqi, I.S.22
more..
-
28
-
-
66049133685
-
Leptin-dependent control of glucose balance and locomotor activity by POMC neurons
-
Huo L, Gamber K, Greeley S, Silva J, Huntoon N, Leng XH, Bjørbaek C 2009 Leptin-dependent control of glucose balance and locomotor activity by POMC neurons. Cell Metab 9:537-547
-
(2009)
Cell Metab
, vol.9
, pp. 537-547
-
-
Huo, L.1
Gamber, K.2
Greeley, S.3
Silva, J.4
Huntoon, N.5
Leng, X.H.6
Bjørbaek, C.7
-
29
-
-
0032014178
-
Identification of SOCS-3 as a potential mediator of central leptin resistance
-
Bjørbaek C, Elmquist JK, Frantz JD, Shoelson SE, Flier JS 1998 Identification of SOCS-3 as a potential mediator of central leptin resistance. Mol Cell 1:619-625
-
(1998)
Mol Cell
, vol.1
, pp. 619-625
-
-
Bjørbaek, C.1
Elmquist, J.K.2
Frantz, J.D.3
Shoelson, S.E.4
Flier, J.S.5
-
30
-
-
0034717062
-
SOCS-3 is an insulin-induced negative regulator of insulin signaling
-
Emanuelli B, Peraldi P, Filloux C, Sawka-Verhelle D, Hilton D, Van Obberghen E 2000 SOCS-3 is an insulin-induced negative regulator of insulin signaling. J Biol Chem 275:15985-15991
-
(2000)
J Biol Chem
, vol.275
, pp. 15985-15991
-
-
Emanuelli, B.1
Peraldi, P.2
Filloux, C.3
Sawka-Verhelle, D.4
Hilton, D.5
Van Obberghen, E.6
-
31
-
-
0022510796
-
Autoradiographic localization of insulin receptors in rat brain: Prominence in olfactory and limbic areas
-
Hill JM, Lesniak MA, Pert CB, Roth J 1986 Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas. Neuroscience 17:1127-1138
-
(1986)
Neuroscience
, vol.17
, pp. 1127-1138
-
-
Hill, J.M.1
Lesniak, M.A.2
Pert, C.B.3
Roth, J.4
-
32
-
-
0023271871
-
Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry
-
Werther GA, Hogg A, Oldfield BJ, McKinley MJ, Figdor R, Allen AM, Mendelsohn FA 1987 Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry. Endocrinology 121:1562-1570
-
(1987)
Endocrinology
, vol.121
, pp. 1562-1570
-
-
Werther, G.A.1
Hogg, A.2
Oldfield, B.J.3
McKinley, M.J.4
Figdor, R.5
Allen, A.M.6
Mendelsohn, F.A.7
-
33
-
-
11144310116
-
Identification of ghrelin and its receptor in neurons of the rat arcuate nucleus
-
Mondal MS, Date Y, Yamaguchi H, Toshinai K, Tsuruta T, Kangawa K, NakazatoM2005 Identification of ghrelin and its receptor in neurons of the rat arcuate nucleus. Regul Pept 126:55-59
-
(2005)
Regul Pept
, vol.126
, pp. 55-59
-
-
Mondal, M.S.1
Date, Y.2
Yamaguchi, H.3
Toshinai, K.4
Tsuruta, T.5
Kangawa, K.6
NakazatoM7
|