Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity

Journal of Biological Chemistry

Volumn 277, Issue 48, 2002, Pages 46131-46139

  Long II, Delwin J ^a   Iskander, Karim ^a   Gaikwad, Amos ^a,c   Arin, Meral ^a   Roop, Dennis R ^a   Knox, Richard ^b   Barrios, Roberto ^a   Jaiswal, Anil K ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Enact Pharma PLC   (United Kingdom)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BLOOD; BONE; GENES; METABOLISM; TOXICITY;

BONE MARROW;

ENZYMES;

DIHYDRONICOTINAMIDE RIBOSIDE:QUINONE OXIDOREDUCTASE 2; FLAVOPROTEIN; MENADIONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BASOPHIL; BONE MARROW CELL; BONE MARROW DISEASE; CONTROLLED STUDY; EOSINOPHIL; GENE DISRUPTION; GENE EXPRESSION; GRANULOCYTE; LIVER TOXICITY; MOUSE; MYELOID HYPERPLASIA; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE;

ANIMALS; BASE SEQUENCE; BONE MARROW; CLONING, MOLECULAR; DNA PRIMERS; FERTILITY; FLOW CYTOMETRY; HYPERPLASIA; LIVER; MICE; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; QUINONE REDUCTASES; VITAMIN K 3;

ANIMALIA;

EID: 0037195924     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208675200     Document Type: Article

References (39)

1. O'Brien, P. J. (1991) Chem. Biol. Interact. 80, 1-41
2. Riley, R. J., and Workman, P. (1992) Biochem. Pharmacol. 43, 1657-1669
3. Dinkova-Kostova, A. T., and Talalay, P. (2000) Free Radic. Biol. Med. 29, 231-240
4. Ross, D., Kepa, J. K., Winski, S. L., Beall, H. D., Anwar, A., and Siegel, D. (2000) Chem. Biol. Interact. 129, 77-97
5. Sarvankumar, D., Long, D. J., II, and Jaiswal, A. K. (2000) Curr. Top. Cell. Regul. 36, 201-206
6. Jaiswal, A. K., Bell, D. W., Radjendirane, V., and Testa, J. R. (1999) Pharmacogenetics 9, 413-418
7. Ross, D., Beall, H., Traver, R. D., Siegel, D., Phillips, R. M., and Gibson, N. W. (1994) Oncology Res. 6, 493-500
8. Rauth, A. M., Goldberg, Z., and Misra, V. (1997) Oncology Res. 9, 339-349
9. Rothman, N., Smith, M. T., Hayes, R. B., Traver, R. D., Hoener, B., Campleman, S., Li, G. L., Dosemeci, M., Linet, M., Zhang, L., Xi, L., Wacholder, S., Lu, W., Meyer, K. B., Titenko-Holland, N., Stewart, J. T., Yin, S., and Ross, D. (1997) Cancer Res. 57, 2839-2842
10. Moran, J. L., Siegel, D., and Ross, D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 8150-8155
11. Smith, M. T. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7624-7626
12. Larson, R. A., Wang, Y., Banerjee, M., Wiemels, J., Hartford, C., Le Beau, M. M., and Smith, M. T. (1999) Blood 94, 803-807
13. Workman, P., and Stratford, I. J. (1993) Cancer Metastasis Rev. 12, 73-82
14. Begleiter, A., Leith, M. K., Curphey, T. J., and Doherty, G. P. (1997) Oncology Res. 9, 371-382
15. Boyer, M. J. (1997) Oncology Res. 9, 391-395
16. Sartorelli, A. C., Hodnick, W. F., Belcourt, M. F., Tomasz, M., Haffty, B., Fischer, J. J., and Rockwell, S. (1994) Oncology Res. 6, 501-508
17. Workman, P. (1994) Oncology Res. 6, 461-475
18. Joseph, P., Xu, Y., and Jaiswal, A. K. (1996) Int. J. Cancer 65, 263-271
19. Radjendirane, V., Joseph, P., Lee, Y. H., Kimura, S., Klein-Sazanto, A. J. P., Gonzalez, F. J., and Jaiswal, A. K. (1998) J. Biol. Chem. 273, 7382-7389
20. Gaikwad, A., Long, D. J., II, Stringer, J. L., and Jaiswal, A. K (2001) J. Biol. Chem. 276, 22559-22564
21. Long, D. J., II, Gaikwad, A., Multani, A., Pathak, S., Montgomery, C. A., Gonzalez, F. J., and Jaiswal, A. K. (2002) Cancer Res. 62, 3030-3036
22. Long, D. J., II, Waikel, R. L., Wang, X., Perlaky, L., Roop, D. R., and Jaiswal, A. K. (2000) Cancer Res. 60, 5913-5915
23. Long, D. J., II, Waikel, R. L., Wang, X. J., Roop, D. R., and Jaiswal, A. K. (2001) J. Natl. Cancer Inst. 93, 1166-1170
24. Jaiswal, A. K., Burnett, P., Adesnik, M., and McBride, O. W. (1990) Biochemistry 29, 1899-1906
25. Wu, K. B., Knox, R., Sun, X. Z., Joseph, P., Jaiswal, A. K., Zhang, D., Deng, P. S. K., and Chen, S. (1997) Arch. Biochem. Biophys. 347, 221-228
26. Zhao, Q., Yang, X. L., Holtzclaw, W. D., and Talalay, P. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1669-1674
27. Foster, C. E., Bianchet, M. A., Talalay, P., Zhao, Q., and Amzel, L. M. (1999) Biochemistry 38, 9881-9886
28. Long, D. J., II, and Jaiswal, A. K. (2000) Gene (Amst.) 252, 107-117
29. Tybulewicz, V. L. J., Crawford, C. E., Jackson, P. K., Bronson, R. J., and Mulligan, R. C. (1991) Cell 65, 1153-1163
30. Laird, P. W., Zijderveld, A., Linders, K., Rudnicki, M. A., Jaenisch, R., and Berns, A. (1991) Nucleic Acids Res. 19, 4293
31. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Rotter, W. J. (1979) Biochemistry 18, 5294-5304
32. Church, G. M., and Gilbert, W. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 1991-1995
33. Shaw, P. M., Reiss, A., Adesnik, M., Nebert, D. W., Schembri, J., and Jaiswal, A. K. (1991) Eur. J. Biochem. 195, 171-176
34. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
35. Knox, R. J., Jenkins, J. C., Hobbs, S. M., Chen, S., Melton, R. G., and Burke, P. J. (2000) Cancer Res. 60, 4179-4186
36. Chesis, P. L., Levin, D. E., Smith, M. T., Ernster, L., and Ames, B. N. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 1696-1700
37. Lind, C. (1985) Arch. Biochem. Biophys. 280, 226-235
38. De Flora, A. (1985) Cancer Res. 45, 3188-3196
39. Chen, S., Wu, K., and Knox, R. (2000) Free Radic. Biol. Med. 29, 276-284