메뉴 건너뛰기




Volumn 4, Issue 3, 2009, Pages 202-213

Carotid artery disease: Current concepts on endothelial dysfunction and matrix remodeling

Author keywords

ADMA; Carotid atherosclerosis; Endothelial dysfunction; Extracellular matrix; MMPs; NO

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; ARGININE; CHLORTALIDONE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FLUORODEOXYGLUCOSE F 18; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IRBESARTAN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; NITRIC OXIDE DONOR; PLACEBO; PRAVASTATIN; ROSIGLITAZONE; ROSUVASTATIN;

EID: 73449088002     PISSN: 15748855     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488509789054974     Document Type: Review
Times cited : (1)

References (153)
  • 1
    • 0035846302 scopus 로고    scopus 로고
    • Clinical practice. Extracranial carotid stenosis
    • Sacco RL. Clinical practice. Extracranial carotid stenosis. N Engl J Med 2001; 345: 1113-18.
    • (2001) N Engl J Med , vol.345 , pp. 1113-1118
    • Sacco, R.L.1
  • 2
    • 2342492418 scopus 로고    scopus 로고
    • Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: Randomised controlled trial
    • Halliday A, Mansfield A, Marro J, et al. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet 2004; 363: 1491-02.
    • (2004) Lancet , vol.363 , pp. 1491-1502
    • Halliday, A.1    Mansfield, A.2    Marro, J.3
  • 3
    • 0028938324 scopus 로고
    • Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study
    • Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA 1995; 273: 1421-28.
    • (1995) JAMA , vol.273 , pp. 1421-1428
  • 6
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - an inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999; 340: 115-26.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 7
    • 1942440941 scopus 로고    scopus 로고
    • Thrombogenesis, atherogenesis and angiogenesis in vascular disease: A new 'vascular triad'
    • Lip GY, Blann AD. Thrombogenesis, atherogenesis and angiogenesis in vascular disease: a new 'vascular triad'. Ann Med 2004; 36: 119-25.
    • (2004) Ann Med , vol.36 , pp. 119-125
    • Lip, G.Y.1    Blann, A.D.2
  • 8
    • 0037155057 scopus 로고    scopus 로고
    • Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly
    • Galis, ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ Res 2002; 90: 251-62.
    • (2002) Circ Res , vol.90 , pp. 251-262
    • Galis, Z.S.1    Khatri, J.J.2
  • 9
    • 0028300301 scopus 로고
    • The emerging concept of vascular remodeling
    • Gibbons GH, Dzau VJ. The emerging concept of vascular remodeling. N Engl J Med 1994; 330: 1431-38.
    • (1994) N Engl J Med , vol.330 , pp. 1431-1438
    • Gibbons, G.H.1    Dzau, V.J.2
  • 10
    • 0029806559 scopus 로고    scopus 로고
    • The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis
    • Assoian RK, Marcantonio EE. The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis. J Clin Invest 1996; 98: 2436-39.
    • (1996) J Clin Invest , vol.98 , pp. 2436-2439
    • Assoian, R.K.1    Marcantonio, E.E.2
  • 11
    • 0026597265 scopus 로고
    • A definition of the intima of human arteries and of its atherosclerosis-prone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association
    • Stary HC, Blankenhorn DH, Chandler AB, et al. A definition of the intima of human arteries and of its atherosclerosis-prone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Arterioscler Thromb 1992; 12: 120-34.
    • (1992) Arterioscler Thromb , vol.12 , pp. 120-134
    • Stary, H.C.1    Blankenhorn, D.H.2    Chandler, A.B.3
  • 12
    • 0023202880 scopus 로고    scopus 로고
    • Shekhonin BV, Domogatsky SP, Idelson GL, Koteliansky VE, Rukosuev VS. Relative distribution of fibronectin and type I, III, IV, V collagens in normal and atherosclerotic intima of human arteries. Atherosclerosis 1987; 67: 9-16.
    • Shekhonin BV, Domogatsky SP, Idelson GL, Koteliansky VE, Rukosuev VS. Relative distribution of fibronectin and type I, III, IV, V collagens in normal and atherosclerotic intima of human arteries. Atherosclerosis 1987; 67: 9-16.
  • 14
    • 0030271572 scopus 로고    scopus 로고
    • Macromolecular organization of basement membranes
    • Timpl R. Macromolecular organization of basement membranes. Curr Opin Cell Biol 1996; 8: 618-24.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 618-624
    • Timpl, R.1
  • 15
    • 0034037764 scopus 로고    scopus 로고
    • Normal endothelial cell function
    • Pearson JD. Normal endothelial cell function. Lupus 2000; 9: 183-88.
    • (2000) Lupus , vol.9 , pp. 183-188
    • Pearson, J.D.1
  • 16
    • 0032525207 scopus 로고    scopus 로고
    • Endothelial cells in physiology and in the pathophysiology of vascular disorders
    • Cines DB, Pollak ES, Buck CA, et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 1998; 91: 3527-61.
    • (1998) Blood , vol.91 , pp. 3527-3561
    • Cines, D.B.1    Pollak, E.S.2    Buck, C.A.3
  • 17
    • 0032474270 scopus 로고    scopus 로고
    • Endothelial cell activation. A central pathophysiological process
    • Hunt BJ, Jurd KM. Endothelial cell activation. A central pathophysiological process. BMJ 1998; 316: 1328-29.
    • (1998) BMJ , vol.316 , pp. 1328-1329
    • Hunt, B.J.1    Jurd, K.M.2
  • 18
    • 0024249545 scopus 로고    scopus 로고
    • Pober JS. Warner-Lambert/Parke-Davis award lecture. Cytokine-mediated activation of vascular endothelium. Physiology and pathology. Am J Pathol 1988; 133: 426-33.
    • Pober JS. Warner-Lambert/Parke-Davis award lecture. Cytokine-mediated activation of vascular endothelium. Physiology and pathology. Am J Pathol 1988; 133: 426-33.
  • 19
    • 0025283892 scopus 로고
    • Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension
    • Panza JA, Quyyumi AA, Brush JE, Jr, Epstein SE. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990; 323: 22-7.
    • (1990) N Engl J Med , vol.323 , pp. 22-27
    • Panza, J.A.1    Quyyumi, A.A.2    Brush Jr, J.E.3    Epstein, S.E.4
  • 20
    • 0035127180 scopus 로고    scopus 로고
    • Correlation of endothelial function in large and small arteries in human essential hypertension
    • Park JB, Charbonneau F, Schiffrin EL. Correlation of endothelial function in large and small arteries in human essential hypertension. J Hypertens 2001; 19: 415-20.
    • (2001) J Hypertens , vol.19 , pp. 415-420
    • Park, J.B.1    Charbonneau, F.2    Schiffrin, E.L.3
  • 21
    • 18244371468 scopus 로고    scopus 로고
    • Endothelial dysfunction in patients with coronary artery disease: A comparison of three frequently reported tests
    • Monnink SH, van Haelst PL, van Boven AJ. Endothelial dysfunction in patients with coronary artery disease: a comparison of three frequently reported tests. J Investig Med 2002; 50: 19-4.
    • (2002) J Investig Med , vol.50 , pp. 19-24
    • Monnink, S.H.1    van Haelst, P.L.2    van Boven, A.J.3
  • 22
    • 0037058827 scopus 로고    scopus 로고
    • Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: Role of xanthine-oxidase and extracellular superoxide dismutase
    • Landmesser U, Spiekermann S, Dikalov S, et al. Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase. Circulation 2002; 106: 3073-78.
    • (2002) Circulation , vol.106 , pp. 3073-3078
    • Landmesser, U.1    Spiekermann, S.2    Dikalov, S.3
  • 23
    • 0035814950 scopus 로고    scopus 로고
    • Structural alterations in subcutaneous small arteries of normotensive and hypertensive patients with non-insulin-dependent diabetes mellitus
    • Rizzoni D, Porteri E, Guelfi D, et al. Structural alterations in subcutaneous small arteries of normotensive and hypertensive patients with non-insulin-dependent diabetes mellitus. Circulation 2001; 103: 1238-44.
    • (2001) Circulation , vol.103 , pp. 1238-1244
    • Rizzoni, D.1    Porteri, E.2    Guelfi, D.3
  • 24
    • 0034970869 scopus 로고    scopus 로고
    • Endothelial dysfunction in chronic renal failure: Roles of lipoprotein oxidation and proinflammatory cytokines
    • Bolton CH, Downs LG, Victory JG, et al. Endothelial dysfunction in chronic renal failure: roles of lipoprotein oxidation and proinflammatory cytokines. Nephrol Dial Transplant 2001; 16: 1189-97.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1189-1197
    • Bolton, C.H.1    Downs, L.G.2    Victory, J.G.3
  • 25
    • 0346492594 scopus 로고    scopus 로고
    • Weight reduction with very-low-caloric diet and endothelial function in overweight adults: Role of plasma glucose
    • Raitakari M, Ilvonen T, Ahotupa M, et al. Weight reduction with very-low-caloric diet and endothelial function in overweight adults: role of plasma glucose. Arterioscler Thromb Vasc Biol 2004; 24: 124-28.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 124-128
    • Raitakari, M.1    Ilvonen, T.2    Ahotupa, M.3
  • 26
    • 0034812039 scopus 로고    scopus 로고
    • Mechanisms responsible for endothelial dysfunction induced by fasting hyperhomocystinemia in normotensive subjects and patients with essential hypertension
    • Virdis A, Ghiadoni L, Cardinal H, et al. Mechanisms responsible for endothelial dysfunction induced by fasting hyperhomocystinemia in normotensive subjects and patients with essential hypertension. J Am Coll Cardiol 2001; 38: 1106-15.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1106-1115
    • Virdis, A.1    Ghiadoni, L.2    Cardinal, H.3
  • 27
    • 0042510744 scopus 로고    scopus 로고
    • Effect of cilostazol on impaired vasodilatory response of the brachial artery to ischemia in smokers
    • Oida K, Ebata K, Kanehara H, Suzuki J, Miyamori I. Effect of cilostazol on impaired vasodilatory response of the brachial artery to ischemia in smokers. J Atheroscler Thromb 2003; 10: 93-8.
    • (2003) J Atheroscler Thromb , vol.10 , pp. 93-98
    • Oida, K.1    Ebata, K.2    Kanehara, H.3    Suzuki, J.4    Miyamori, I.5
  • 28
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-12.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 29
    • 0028332056 scopus 로고
    • Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions
    • Forstermann U, Closs EI, Pollock JS, et al. Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. Hypertension 1994; 23: 1121-31.
    • (1994) Hypertension , vol.23 , pp. 1121-1131
    • Forstermann, U.1    Closs, E.I.2    Pollock, J.S.3
  • 30
    • 0031054463 scopus 로고    scopus 로고
    • Nitric oxide synthase: Role in the genesis of vascular disease
    • Cooke JP, Dzau VJ. Nitric oxide synthase: role in the genesis of vascular disease. Annu Rev Med 1997; 48: 489-509.
    • (1997) Annu Rev Med , vol.48 , pp. 489-509
    • Cooke, J.P.1    Dzau, V.J.2
  • 31
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P, Leone A, Calver A, Collier J, Moncada S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 1992; 339: 572-5.
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 33
    • 0035705616 scopus 로고    scopus 로고
    • Nitric oxide and atherosclerosis
    • Napoli C, Ignarro LJ. Nitric oxide and atherosclerosis. Nitric Oxide 2001; 5: 88-97.
    • (2001) Nitric Oxide , vol.5 , pp. 88-97
    • Napoli, C.1    Ignarro, L.J.2
  • 34
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991; 88: 4651-5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 35
    • 0033537633 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthase inhibitor: A novel marker of atherosclerosis
    • Miyazaki H, Matsuoka H, Cooke JP, et al. Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. Circulation 1999; 99: 1141-6.
    • (1999) Circulation , vol.99 , pp. 1141-1146
    • Miyazaki, H.1    Matsuoka, H.2    Cooke, J.P.3
  • 36
    • 0028809857 scopus 로고
    • Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats
    • Numaguchi K, Egashira K, Takemoto M, et al. Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats. Hypertension 1995; 26: 957-62.
    • (1995) Hypertension , vol.26 , pp. 957-962
    • Numaguchi, K.1    Egashira, K.2    Takemoto, M.3
  • 37
    • 0025214621 scopus 로고
    • Persistent dysfunction of regenerated endothelium after balloon angioplasty of rabbit iliac artery
    • Weidinger FF, McLenachan JM, Cybulsky MI, et al. Persistent dysfunction of regenerated endothelium after balloon angioplasty of rabbit iliac artery. Circulation 1990; 81: 1667-79.
    • (1990) Circulation , vol.81 , pp. 1667-1679
    • Weidinger, F.F.1    McLenachan, J.M.2    Cybulsky, M.I.3
  • 38
    • 0036084587 scopus 로고    scopus 로고
    • Long-term inhibition of nitric oxide synthesis increases arterial thrombogenecity in rat carotid artery
    • Kubo-Inoue M, Egashira K, Usui M, et al. Long-term inhibition of nitric oxide synthesis increases arterial thrombogenecity in rat carotid artery. Am J Physiol Heart Circ Physiol 2002; 282: H1478-84.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Kubo-Inoue, M.1    Egashira, K.2    Usui, M.3
  • 40
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • Rees DD, Palmer RM, Schulz R, Hodson HF, Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 1990; 101: 746-52.
    • (1990) Br J Pharmacol , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 41
    • 0024340138 scopus 로고    scopus 로고
    • Ogawa T, Kimoto M, Sasaoka K. Purification and properties of a new enzyme, NG,NG-dimethylarginine dimethylaminohydrolase, from rat kidney. J Biol Chem 1989; 264: 10205-9.
    • Ogawa T, Kimoto M, Sasaoka K. Purification and properties of a new enzyme, NG,NG-dimethylarginine dimethylaminohydrolase, from rat kidney. J Biol Chem 1989; 264: 10205-9.
  • 42
    • 12244262222 scopus 로고    scopus 로고
    • Asymmetrical dimethylarginine (ADMA) in critically ill patients: High plasma ADMA concentration is an independent risk factor of ICU mortality
    • Nijveldt RJ, Teerlink T, Van Der Hoven B, et al. Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality. Clin Nutr 2003; 22: 23-30.
    • (2003) Clin Nutr , vol.22 , pp. 23-30
    • Nijveldt, R.J.1    Teerlink, T.2    Van Der Hoven, B.3
  • 43
    • 0030473408 scopus 로고    scopus 로고
    • Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase
    • MacAllister RJ, Parry H, Kimoto M, et al. Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase. Br J Pharmacol 996; 119: 1533-40.
    • Br J Pharmacol , vol.996 , Issue.119 , pp. 1533-1540
    • MacAllister, R.J.1    Parry, H.2    Kimoto, M.3
  • 44
    • 0041357001 scopus 로고    scopus 로고
    • Endothelial dysfunction induced by hyperhomocyst(e)inemia: Role of asymmetric dimethylarginine
    • Stuhlinger MC, Oka, RK, Graf EE, et al. Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. Circulation 2003; 108: 933-8.
    • (2003) Circulation , vol.108 , pp. 933-938
    • Stuhlinger, M.C.1    Oka, R.K.2    Graf, E.E.3
  • 45
    • 0242322346 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA): A novel risk factor for endothelial dysfunction: its role in hypercholesterolemia
    • Boger RH, Bode-Boger SM, Szuba A, et al. Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 1998; 98: 1842-7.
    • (1998) Circulation , vol.98 , pp. 1842-1847
    • Boger, R.H.1    Bode-Boger, S.M.2    Szuba, A.3
  • 46
    • 0037143637 scopus 로고    scopus 로고
    • Impaired nitric oxide synthase pathway in diabetes mellitus: Role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase
    • Lin KY, Ito A, Asagami T, et al. Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 2002; 106: 987-92.
    • (2002) Circulation , vol.106 , pp. 987-992
    • Lin, K.Y.1    Ito, A.2    Asagami, T.3
  • 47
    • 0032912757 scopus 로고    scopus 로고
    • Reduced urinary excretion of nitric oxide metabolites and increased plasma levels of asymmetric dimethylarginine in men with essential hypertension
    • Surdacki A, Nowicki M, Sandmann J, et al. Reduced urinary excretion of nitric oxide metabolites and increased plasma levels of asymmetric dimethylarginine in men with essential hypertension. J Cardiovasc Pharmacol 1999; 33: 652-8.
    • (1999) J Cardiovasc Pharmacol , vol.33 , pp. 652-658
    • Surdacki, A.1    Nowicki, M.2    Sandmann, J.3
  • 48
    • 0035889591 scopus 로고    scopus 로고
    • Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus
    • Abbasi F, Asagmi T, Cooke JP, et al. Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus. Am J Cardiol 2001; 88: 1201-3.
    • (2001) Am J Cardiol , vol.88 , pp. 1201-1203
    • Abbasi, F.1    Asagmi, T.2    Cooke, J.P.3
  • 49
    • 0037216677 scopus 로고    scopus 로고
    • ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: Effects of L-arginine and B vitamins
    • Sydow K, Schwedhelm E, Arakawa N, et al. ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. Cardiovasc Res 2003; 57: 244-52.
    • (2003) Cardiovasc Res , vol.57 , pp. 244-252
    • Sydow, K.1    Schwedhelm, E.2    Arakawa, N.3
  • 50
    • 0036460659 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA): A potential link between endothelial dysfunction and cardiovascular diseases in insulin resistance syndrome?
    • Chan NN, Chan JC. Asymmetric dimethylarginine (ADMA): a potential link between endothelial dysfunction and cardiovascular diseases in insulin resistance syndrome? Diabetologia 2002; 45: 1609-16.
    • (2002) Diabetologia , vol.45 , pp. 1609-1616
    • Chan, N.N.1    Chan, J.C.2
  • 51
    • 0036156916 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease
    • Zoccali C, Benedetto FA, Maas R, et al. Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease. J Am Soc Nephrol 2002; 13: 490-6.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 490-496
    • Zoccali, C.1    Benedetto, F.A.2    Maas, R.3
  • 52
    • 27744511357 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: Results from the AtheroGene Study
    • Schnabel R, Blankenberg S, Lubos E, et al. Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene Study. Circ Res 2005; 97: e53-9.
    • (2005) Circ Res , vol.97
    • Schnabel, R.1    Blankenberg, S.2    Lubos, E.3
  • 53
    • 0242640310 scopus 로고    scopus 로고
    • Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease
    • Boger RH, Bode-Boger SM, Thiele W, Junker W, Alexander K, Frolich JC. Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease. Circulation 1997; 95: 2068-74.
    • (1997) Circulation , vol.95 , pp. 2068-2074
    • Boger, R.H.1    Bode-Boger, S.M.2    Thiele, W.3    Junker, W.4    Alexander, K.5    Frolich, J.C.6
  • 54
    • 0034813226 scopus 로고    scopus 로고
    • Elevated levels of plasma homocyst(e)ine and asymmetric dimethylarginine in elderly patients with stroke
    • Yoo JH., Lee SC. Elevated levels of plasma homocyst(e)ine and asymmetric dimethylarginine in elderly patients with stroke. Atherosclerosis 2001; 158: 425-30.
    • (2001) Atherosclerosis , vol.158 , pp. 425-430
    • Yoo, J.H.1    Lee, S.C.2
  • 55
    • 33644559016 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA) as a risk marker for stroke and TIA in a Swedish population
    • Wanby P, Teerlink T, Brudin L, et al. Asymmetric dimethylarginine (ADMA) as a risk marker for stroke and TIA in a Swedish population. Atherosclerosis 2006; 185: 271-7.
    • (2006) Atherosclerosis , vol.185 , pp. 271-277
    • Wanby, P.1    Teerlink, T.2    Brudin, L.3
  • 56
    • 33747186695 scopus 로고    scopus 로고
    • ADMA increases arterial stiffness and decreases cerebral blood flow in humans
    • Kielstein JT, Donnerstag F, Gasper S, et al. ADMA increases arterial stiffness and decreases cerebral blood flow in humans. Stroke 2006; 37: 2024-9.
    • (2006) Stroke , vol.37 , pp. 2024-2029
    • Kielstein, J.T.1    Donnerstag, F.2    Gasper, S.3
  • 57
    • 33846856491 scopus 로고    scopus 로고
    • Plasma levels of asymmetric dimethylarginine (ADMA) are related to intima-media thickness of the carotid artery: An epidemiological study
    • Furuki K, Adachi H, Matsuoka H, et al. Plasma levels of asymmetric dimethylarginine (ADMA) are related to intima-media thickness of the carotid artery: an epidemiological study. Atherosclerosis 2007; 191: 206-10.
    • (2007) Atherosclerosis , vol.191 , pp. 206-210
    • Furuki, K.1    Adachi, H.2    Matsuoka, H.3
  • 58
    • 0034975920 scopus 로고    scopus 로고
    • Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine
    • Lundman P, Eriksson, MJ, Stuhlinger M, Cooke JP, Hamsten A, Tornvall P. Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine. J Am Coll Cardiol 2001; 38: 111-6.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 111-116
    • Lundman, P.1    Eriksson, M.J.2    Stuhlinger, M.3    Cooke, J.P.4    Hamsten, A.5    Tornvall, P.6
  • 59
    • 48349085576 scopus 로고    scopus 로고
    • Plasma level of asymmetric dimethylarginine (ADMA) as a predictor of carotid intima-media thickness progression: Six-year prospective study using carotid ultrasonography
    • Furuki K, Adachi H, Enomoto M, et al. Plasma level of asymmetric dimethylarginine (ADMA) as a predictor of carotid intima-media thickness progression: six-year prospective study using carotid ultrasonography. Hypertens Res 2008; 31: 1185-9.
    • (2008) Hypertens Res , vol.31 , pp. 1185-1189
    • Furuki, K.1    Adachi, H.2    Enomoto, M.3
  • 60
    • 33845865529 scopus 로고    scopus 로고
    • Increased plasma levels of asymmetric dimethylarginine in patients with carotid stenosis: No evidence for the role of the common FABP2 A54T gene polymorphism
    • Wanby P, Nilsson I, Brudin L, Nyhammar I, Gustafsson I, Carlsson M. Increased plasma levels of asymmetric dimethylarginine in patients with carotid stenosis: no evidence for the role of the common FABP2 A54T gene polymorphism. Acta Neurol Scand 2007; 115: 90-6.
    • (2007) Acta Neurol Scand , vol.115 , pp. 90-96
    • Wanby, P.1    Nilsson, I.2    Brudin, L.3    Nyhammar, I.4    Gustafsson, I.5    Carlsson, M.6
  • 61
    • 30944453002 scopus 로고    scopus 로고
    • Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure
    • Nanayakkara PW, Teerlink T, Stehouwer CD, et al. Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure. Kidney Int 2005; 68: 2230-6.
    • (2005) Kidney Int , vol.68 , pp. 2230-2236
    • Nanayakkara, P.W.1    Teerlink, T.2    Stehouwer, C.D.3
  • 63
    • 33750462314 scopus 로고    scopus 로고
    • Level of asymmetric dimethylarginine and carotid atherosclerosis in patients with chronic kidney disease
    • Zhang WR, Hou FF, Ning JP, et al. Level of asymmetric dimethylarginine and carotid atherosclerosis in patients with chronic kidney disease. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006; 31: 621-8.
    • (2006) Zhong Nan Da Xue Xue Bao Yi Xue Ban , vol.31 , pp. 621-628
    • Zhang, W.R.1    Hou, F.F.2    Ning, J.P.3
  • 64
    • 0035830412 scopus 로고    scopus 로고
    • Hydroxymethylglutaryl- coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance
    • Feron O, Dessy C, Desager JP, Balligand JL. Hydroxymethylglutaryl- coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance. Circulation 2001; 103: 113-8.
    • (2001) Circulation , vol.103 , pp. 113-118
    • Feron, O.1    Dessy, C.2    Desager, J.P.3    Balligand, J.L.4
  • 65
    • 17044427138 scopus 로고    scopus 로고
    • Inflammation and endothelial dysfunction as therapeutic targets in patients with heart failure
    • Tousoulis D, Charakida M, Stefanadis C. Inflammation and endothelial dysfunction as therapeutic targets in patients with heart failure. Int J Cardiol 2005; 100: 347-53.
    • (2005) Int J Cardiol , vol.100 , pp. 347-353
    • Tousoulis, D.1    Charakida, M.2    Stefanadis, C.3
  • 66
    • 33845642067 scopus 로고    scopus 로고
    • Novel therapies targeting vascular endothelium
    • Tousoulis D, Antoniades C, Koumallos N, et al. Novel therapies targeting vascular endothelium. Endothelium 2006; 13: 411-21.
    • (2006) Endothelium , vol.13 , pp. 411-421
    • Tousoulis, D.1    Antoniades, C.2    Koumallos, N.3
  • 67
    • 1842583832 scopus 로고    scopus 로고
    • Effects of conventional and aggressive statin treatment on markers of endothelial function and inflammation
    • Hognestad A, Aukrust P, Wergeland R, et al. Effects of conventional and aggressive statin treatment on markers of endothelial function and inflammation. Clin Cardiol 2004: 27: 199-203.
    • (2004) Clin Cardiol , vol.27 , pp. 199-203
    • Hognestad, A.1    Aukrust, P.2    Wergeland, R.3
  • 68
    • 0032555170 scopus 로고    scopus 로고
    • Increased bioavailability of nitric oxide after lipid-lowering therapy in hypercholesterolemic patients: A randomized, placebo-controlled, double-blind study
    • John S, Schlaich M, Langenfeld M, et al. Increased bioavailability of nitric oxide after lipid-lowering therapy in hypercholesterolemic patients: a randomized, placebo-controlled, double-blind study. Circulation 1998; 98: 211-6.
    • (1998) Circulation , vol.98 , pp. 211-216
    • John, S.1    Schlaich, M.2    Langenfeld, M.3
  • 69
    • 3142606890 scopus 로고    scopus 로고
    • Effect of rosuvastatin on plasma levels of asymmetric dimethylarginine in patients with hypercholesterolemia
    • Lu TM, Ding YA, Leu HB, Yin WH, Sheu WH, Chu KM. Effect of rosuvastatin on plasma levels of asymmetric dimethylarginine in patients with hypercholesterolemia. Am J Cardiol 2004; 94: 157-61.
    • (2004) Am J Cardiol , vol.94 , pp. 157-161
    • Lu, T.M.1    Ding, Y.A.2    Leu, H.B.3    Yin, W.H.4    Sheu, W.H.5    Chu, K.M.6
  • 70
    • 0036636922 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension
    • Delles C, Schneider MP, John S, Gekle M, Schmieder RE. Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension. Am J Hypertens 2002; 15: 590-3.
    • (2002) Am J Hypertens , vol.15 , pp. 590-593
    • Delles, C.1    Schneider, M.P.2    John, S.3    Gekle, M.4    Schmieder, R.E.5
  • 71
    • 0026782496 scopus 로고
    • Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension
    • Ribeiro MO, Antunes E, de Nucci G, Lovisolo SM, Zatz R. Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension. Hypertension 1992; 20: 298-303.
    • (1992) Hypertension , vol.20 , pp. 298-303
    • Ribeiro, M.O.1    Antunes, E.2    de Nucci, G.3    Lovisolo, S.M.4    Zatz, R.5
  • 72
    • 1542285171 scopus 로고    scopus 로고
    • Combined treatment with an AT1 receptor blocker and angiotensin converting enzyme inhibitor has an additive effect on inhibiting neointima formation via improvement of nitric oxide production and suppression of oxidative stress
    • Yagi S, Morita T, Katayama S. Combined treatment with an AT1 receptor blocker and angiotensin converting enzyme inhibitor has an additive effect on inhibiting neointima formation via improvement of nitric oxide production and suppression of oxidative stress. Hypertens Res 2004; 27: 129-35.
    • (2004) Hypertens Res , vol.27 , pp. 129-135
    • Yagi, S.1    Morita, T.2    Katayama, S.3
  • 73
    • 0036590626 scopus 로고    scopus 로고
    • Vasoactive substances: Nitric oxide and endothelial dysfunction in atherosclerosis
    • Russo G, Leopold JA, Loscalzo J. Vasoactive substances: nitric oxide and endothelial dysfunction in atherosclerosis. Vascul Pharmacol 2002; 38: 259-69.
    • (2002) Vascul Pharmacol , vol.38 , pp. 259-269
    • Russo, G.1    Leopold, J.A.2    Loscalzo, J.3
  • 74
    • 0037066021 scopus 로고    scopus 로고
    • Functional and biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatment
    • Schulz E, Tsilimingas N, Rinze R, et al. Functional and biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatment. Circulation 2002; 105: 1170-5.
    • (2002) Circulation , vol.105 , pp. 1170-1175
    • Schulz, E.1    Tsilimingas, N.2    Rinze, R.3
  • 75
    • 34249706763 scopus 로고    scopus 로고
    • The l-arginine paradox: Importance of the l-arginine/asymmetrical dimethylarginine ratio
    • Bode-Boger SM, Scalera F, Ignarro LJ. The l-arginine paradox: Importance of the l-arginine/asymmetrical dimethylarginine ratio. Pharmacol Ther 2007; 114: 295-306.
    • (2007) Pharmacol Ther , vol.114 , pp. 295-306
    • Bode-Boger, S.M.1    Scalera, F.2    Ignarro, L.J.3
  • 76
    • 0029993977 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure
    • Rector TS, Bank AJ, Mullen KA, et al. Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure. Circulation 1996; 93: 2135-41.
    • (1996) Circulation , vol.93 , pp. 2135-2141
    • Rector, T.S.1    Bank, A.J.2    Mullen, K.A.3
  • 77
    • 0343306727 scopus 로고    scopus 로고
    • Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris
    • Ceremuzynski L, Chamiec T, Herbaczynska-Cedro K. Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris. Am J Cardiol 1997; 80: 331-3.
    • (1997) Am J Cardiol , vol.80 , pp. 331-333
    • Ceremuzynski, L.1    Chamiec, T.2    Herbaczynska-Cedro, K.3
  • 78
    • 0034014593 scopus 로고    scopus 로고
    • Nutritional therapy for peripheral arterial disease: A double-blind, placebo-controlled, randomized trial of HeartBar
    • Maxwell AJ, Anderson BE, Cooke JP. Nutritional therapy for peripheral arterial disease: a double-blind, placebo-controlled, randomized trial of HeartBar. Vasc Med 2000; 5: 11-9.
    • (2000) Vasc Med , vol.5 , pp. 11-19
    • Maxwell, A.J.1    Anderson, B.E.2    Cooke, J.P.3
  • 80
    • 14244267053 scopus 로고    scopus 로고
    • Chronic L-arginine supplementation improves endothelial cell vasoactive functions in hypercholesterolemic and atherosclerotic monkeys
    • Dhawan V, Handu SS, Nain CK, Ganguly NK. Chronic L-arginine supplementation improves endothelial cell vasoactive functions in hypercholesterolemic and atherosclerotic monkeys. Mol Cell Biochem 2005; 269: 1-11.
    • (2005) Mol Cell Biochem , vol.269 , pp. 1-11
    • Dhawan, V.1    Handu, S.S.2    Nain, C.K.3    Ganguly, N.K.4
  • 81
    • 0026020073 scopus 로고
    • Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta
    • Cooke JP, Andon NA, Girerd XJ, Hirsch AT, Creager MA. Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta. Circulation 1991; 83: 1057-62.
    • (1991) Circulation , vol.83 , pp. 1057-1062
    • Cooke, J.P.1    Andon, N.A.2    Girerd, X.J.3    Hirsch, A.T.4    Creager, M.A.5
  • 82
    • 0342378190 scopus 로고    scopus 로고
    • Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: Comparison with lovastatin
    • Boger RH, Bode-Boger SM, Brandes RP, et al. Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. Circulation 1997; 96: 1282-90.
    • (1997) Circulation , vol.96 , pp. 1282-1290
    • Boger, R.H.1    Bode-Boger, S.M.2    Brandes, R.P.3
  • 83
    • 0025614563 scopus 로고
    • Larginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits
    • Girerd XJ, Hirsch AT, Cooke JP, Dzau VJ, Creager MA. Larginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits. Circ Res 1990; 67: 1301-8.
    • (1990) Circ Res , vol.67 , pp. 1301-1308
    • Girerd, X.J.1    Hirsch, A.T.2    Cooke, J.P.3    Dzau, V.J.4    Creager, M.A.5
  • 84
    • 0037139438 scopus 로고    scopus 로고
    • Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor
    • Stuhlinger MC, Abbasi F, Chu JW, et al. Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA 2002; 287: 1420-6.
    • (2002) JAMA , vol.287 , pp. 1420-1426
    • Stuhlinger, M.C.1    Abbasi, F.2    Chu, J.W.3
  • 85
    • 0034885255 scopus 로고    scopus 로고
    • Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase
    • Murray-Rust J, Leiper J, McAlister M, et al. Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase. Nat Struct Biol 2001; 8: 679-83.
    • (2001) Nat Struct Biol , vol.8 , pp. 679-683
    • Murray-Rust, J.1    Leiper, J.2    McAlister, M.3
  • 86
    • 33846027539 scopus 로고    scopus 로고
    • Farnesoid X receptor agonist reduces serum asymmetric dimethylarginine levels through hepatic dimethylarginine dimethylaminohydrolase-1 gene regulation
    • Hu T, Chouinard M, Cox AL, et al. Farnesoid X receptor agonist reduces serum asymmetric dimethylarginine levels through hepatic dimethylarginine dimethylaminohydrolase-1 gene regulation. J Biol Chem 2006; 281: 39831-8.
    • (2006) J Biol Chem , vol.281 , pp. 39831-39838
    • Hu, T.1    Chouinard, M.2    Cox, A.L.3
  • 87
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994; 94: 2493-503.
    • (1994) J Clin Invest , vol.94 , pp. 2493-2503
    • Galis, Z.S.1    Sukhova, G.K.2    Lark, M.W.3    Libby, P.4
  • 88
    • 5044231289 scopus 로고    scopus 로고
    • Control of smooth muscle cell proliferation in vascular disease
    • Hedin U, Roy J, Tran PK. Control of smooth muscle cell proliferation in vascular disease. Curr Opin Lipidol 2004; 15: 559-65.
    • (2004) Curr Opin Lipidol , vol.15 , pp. 559-565
    • Hedin, U.1    Roy, J.2    Tran, P.K.3
  • 89
    • 0030774116 scopus 로고    scopus 로고
    • Human microvascular endothelial cells differ from macrovascular endothelial cells in their expression of matrix metalloproteinases
    • Jackson CJ, Nguyen M. Human microvascular endothelial cells differ from macrovascular endothelial cells in their expression of matrix metalloproteinases. Int J Biochem Cell Biol 1997; 29: 1167-77.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 1167-1177
    • Jackson, C.J.1    Nguyen, M.2
  • 90
    • 0028625739 scopus 로고
    • The family of matrix metalloproteinases
    • Woessner JF., Jr. The family of matrix metalloproteinases. Ann N Y Acad Sci 1994; 732: 11-21.
    • (1994) Ann N Y Acad Sci , vol.732 , pp. 11-21
    • Woessner Jr., J.F.1
  • 91
    • 31344447802 scopus 로고    scopus 로고
    • Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates
    • Newby AC. Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc Res 2006; 69: 614-24.
    • (2006) Cardiovasc Res , vol.69 , pp. 614-624
    • Newby, A.C.1
  • 92
  • 93
    • 0027131113 scopus 로고
    • A 96-kDa gelatinase induced by TNF-alpha contributes to increased microvascular endothelial permeability
    • Partridge CA, Jeffrey JJ, Malik AB. A 96-kDa gelatinase induced by TNF-alpha contributes to increased microvascular endothelial permeability. Am J Physiol 1993; 265: L438-47.
    • (1993) Am J Physiol , vol.265
    • Partridge, C.A.1    Jeffrey, J.J.2    Malik, A.B.3
  • 94
    • 0030292766 scopus 로고    scopus 로고
    • TNF-alpha and IL-1beta selectively induce expression of 92-kDa gelatinase by human macrophages
    • Saren P, Welgus HG, Kovanen PT. TNF-alpha and IL-1beta selectively induce expression of 92-kDa gelatinase by human macrophages. J Immunol 1996; 157: 4159-65.
    • (1996) J Immunol , vol.157 , pp. 4159-4165
    • Saren, P.1    Welgus, H.G.2    Kovanen, P.T.3
  • 95
    • 6844250127 scopus 로고    scopus 로고
    • Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases
    • d'Ortho MP, Will H, Atkinson S, et al. Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases. Eur J Biochem 1997; 250: 751-7.
    • (1997) Eur J Biochem , vol.250 , pp. 751-757
    • d'Ortho, M.P.1    Will, H.2    Atkinson, S.3
  • 96
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
    • Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 2003; 92: 827-39.
    • (2003) Circ Res , vol.92 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 97
    • 0037058855 scopus 로고    scopus 로고
    • Increased expression of membrane type 3-matrix metalloproteinase in human atherosclerotic plaque: Role of activated macrophages and inflammatory cytokines
    • Uzui H, Harpf A, Liu M, et al. Increased expression of membrane type 3-matrix metalloproteinase in human atherosclerotic plaque: role of activated macrophages and inflammatory cytokines. Circulation 2002; 106: 3024-30.
    • (2002) Circulation , vol.106 , pp. 3024-3030
    • Uzui, H.1    Harpf, A.2    Liu, M.3
  • 98
    • 0027012631 scopus 로고
    • Neutral proteinase expression by human mononuclear phagocytes: A prominent role of cellular differentiation
    • Welgus HG, Senior RM, Parks WC, et al. Neutral proteinase expression by human mononuclear phagocytes: a prominent role of cellular differentiation. Matrix 1992; Suppl 1: 363-7.
    • (1992) Matrix , Issue.SUPPL. 1 , pp. 363-367
    • Welgus, H.G.1    Senior, R.M.2    Parks, W.C.3
  • 99
    • 0025895193 scopus 로고
    • Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)
    • Murphy G, Cockett MI, Ward RV, Docherty AJ. Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP). Biochem J 1991; 277(Pt 1): 277-9.
    • (1991) Biochem J , vol.277 , Issue.PART 1 , pp. 277-279
    • Murphy, G.1    Cockett, M.I.2    Ward, R.V.3    Docherty, A.J.4
  • 100
    • 10544246489 scopus 로고    scopus 로고
    • Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability
    • Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS. Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. J Clin Invest 1996; 98: 2572-9.
    • (1996) J Clin Invest , vol.98 , pp. 2572-2579
    • Rajagopalan, S.1    Meng, X.P.2    Ramasamy, S.3    Harrison, D.G.4    Galis, Z.S.5
  • 101
    • 0029164317 scopus 로고
    • Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis
    • Nikkari ST, O'Brien KD, Ferguson M, et al. Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis. Circulation 1995; 92: 1393-8.
    • (1995) Circulation , vol.92 , pp. 1393-1398
    • Nikkari, S.T.1    O'Brien, K.D.2    Ferguson, M.3
  • 102
    • 3242691404 scopus 로고    scopus 로고
    • Unstable carotid plaques exhibit raised matrix metalloproteinase-8 activity
    • Molloy KJ, Thompson MM, Jones JL, et al. Unstable carotid plaques exhibit raised matrix metalloproteinase-8 activity. Circulation 2004; 110: 337-43.
    • (2004) Circulation , vol.110 , pp. 337-343
    • Molloy, K.J.1    Thompson, M.M.2    Jones, J.L.3
  • 103
    • 4444251024 scopus 로고    scopus 로고
    • Serum values of metalloproteinase-2 and metalloproteinase-9 as related to unstable plaque and inflammatory cells in patients with greater than 70% carotid artery stenosis
    • Alvarez B, Ruiz C, Chacon P, Alvarez-Sabin J, Matas M. Serum values of metalloproteinase-2 and metalloproteinase-9 as related to unstable plaque and inflammatory cells in patients with greater than 70% carotid artery stenosis. J Vasc Surg 2004; 40: 469-75.
    • (2004) J Vasc Surg , vol.40 , pp. 469-475
    • Alvarez, B.1    Ruiz, C.2    Chacon, P.3    Alvarez-Sabin, J.4    Matas, M.5
  • 104
    • 0033982563 scopus 로고    scopus 로고
    • Increased matrix metalloproteinase-9 activity in unstable carotid plaques. A potential role in acute plaque disruption
    • Loftus IM, Naylor AR, Goodall S, et al. Increased matrix metalloproteinase-9 activity in unstable carotid plaques. A potential role in acute plaque disruption. Stroke 2000; 31: 40-7.
    • (2000) Stroke , vol.31 , pp. 40-47
    • Loftus, I.M.1    Naylor, A.R.2    Goodall, S.3
  • 105
    • 2542626086 scopus 로고    scopus 로고
    • Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics
    • Morgan AR, Rerkasem K, Gallagher PJ, et al. Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics. Stroke 2004; 35: 1310-5.
    • (2004) Stroke , vol.35 , pp. 1310-1315
    • Morgan, A.R.1    Rerkasem, K.2    Gallagher, P.J.3
  • 106
    • 0030779199 scopus 로고    scopus 로고
    • Juxtalumenal location of plaque necrosis and neoformation in symptomatic carotid stenosis
    • Bassiouny HS, Sakaguchi Y, Mikucki SA, et al. Juxtalumenal location of plaque necrosis and neoformation in symptomatic carotid stenosis. J Vasc Surg 1997; 26: 585-94.
    • (1997) J Vasc Surg , vol.26 , pp. 585-594
    • Bassiouny, H.S.1    Sakaguchi, Y.2    Mikucki, S.A.3
  • 107
    • 0035099495 scopus 로고    scopus 로고
    • Differential proteolytic activity and induction of apoptosis in fibrous versus atheromatous plaques in carotid atherosclerotic disease
    • Jacob T, Ascher E, Hingorani A, et al. Differential proteolytic activity and induction of apoptosis in fibrous versus atheromatous plaques in carotid atherosclerotic disease. J Vasc Surg 2001; 33: 614-20.
    • (2001) J Vasc Surg , vol.33 , pp. 614-620
    • Jacob, T.1    Ascher, E.2    Hingorani, A.3
  • 108
    • 30944456938 scopus 로고    scopus 로고
    • Altered expression balance of matrix metalloproteinases and their inhibitors in human carotid plaque disruption: Results of quantitative tissue analysis using real-time RT-PCR method
    • Higashikata T, Yamagishi M, Higashi T, et al. Altered expression balance of matrix metalloproteinases and their inhibitors in human carotid plaque disruption: results of quantitative tissue analysis using real-time RT-PCR method." Atherosclerosis 2006; 185: 165-72.
    • (2006) Atherosclerosis , vol.185 , pp. 165-172
    • Higashikata, T.1    Yamagishi, M.2    Higashi, T.3
  • 109
    • 0345465669 scopus 로고    scopus 로고
    • Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques
    • Sukhova GK, Schonbeck U, Rabkin E, et al. Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques. Circulation 1999; 99: 2503-9.
    • (1999) Circulation , vol.99 , pp. 2503-2509
    • Sukhova, G.K.1    Schonbeck, U.2    Rabkin, E.3
  • 110
    • 12244295145 scopus 로고    scopus 로고
    • Activation of metalloproteinases and their association with integrins: An auxiliary apoptotic pathway in human endothelial cells
    • Levkau B, Kenagy RD, Karsan A, et al. Activation of metalloproteinases and their association with integrins: an auxiliary apoptotic pathway in human endothelial cells. Cell Death Differ 2002; 9: 1360-7.
    • (2002) Cell Death Differ , vol.9 , pp. 1360-1367
    • Levkau, B.1    Kenagy, R.D.2    Karsan, A.3
  • 111
    • 33645412966 scopus 로고    scopus 로고
    • C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: Implications for clinical and subclinical atherosclerosis
    • Montero I, Orbe J, Varo N, et al. C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: implications for clinical and subclinical atherosclerosis. J Am Coll Cardiol 2006; 47: 1369-78.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1369-1378
    • Montero, I.1    Orbe, J.2    Varo, N.3
  • 112
    • 0031041367 scopus 로고    scopus 로고
    • Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury
    • Ferry G, Lonchampt M, Pennel L, de Nanteuil G, Canet E, Tucker GC. Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury. FEBS Lett 1997; 402: 111-5.
    • (1997) FEBS Lett , vol.402 , pp. 111-115
    • Ferry, G.1    Lonchampt, M.2    Pennel, L.3    de Nanteuil, G.4    Canet, E.5    Tucker, G.C.6
  • 113
    • 0029084524 scopus 로고
    • Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture
    • Shah PK, Falk E, Badimon JJ, et al. Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 1995; 92: 1565-9.
    • (1995) Circulation , vol.92 , pp. 1565-1569
    • Shah, P.K.1    Falk, E.2    Badimon, J.J.3
  • 114
    • 0030064282 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase activity inhibits smooth muscle cell migration but not neointimal thickening after arterial injury
    • Bendeck MP, Irvin C, Reidy MA. Inhibition of matrix metalloproteinase activity inhibits smooth muscle cell migration but not neointimal thickening after arterial injury. Circ Res 1996; 78: 38-43.
    • (1996) Circ Res , vol.78 , pp. 38-43
    • Bendeck, M.P.1    Irvin, C.2    Reidy, M.A.3
  • 115
    • 0029838645 scopus 로고    scopus 로고
    • Overexpression of tissue inhibitor of matrix metalloproteinase-1 inhibits vascular smooth muscle cell functions in vitro and in vivo
    • Forough R, Koyama N, Hasenstab D, et al. Overexpression of tissue inhibitor of matrix metalloproteinase-1 inhibits vascular smooth muscle cell functions in vitro and in vivo. Circ Res 1996; 79: 812-20.
    • (1996) Circ Res , vol.79 , pp. 812-820
    • Forough, R.1    Koyama, N.2    Hasenstab, D.3
  • 116
    • 0032521142 scopus 로고    scopus 로고
    • Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis
    • Baker AH, Zaltsman AB, George SJ, Newby AC. Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis. J Clin Invest 1998; 101: 1478-87.
    • (1998) J Clin Invest , vol.101 , pp. 1478-1487
    • Baker, A.H.1    Zaltsman, A.B.2    George, S.J.3    Newby, A.C.4
  • 117
    • 0032502944 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein
    • George SJ, Johnson JL, Angelini GD, Newby AC, Baker AH. Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein. Hum Gene Ther 1998; 9: 867-77.
    • (1998) Hum Gene Ther , vol.9 , pp. 867-877
    • George, S.J.1    Johnson, J.L.2    Angelini, G.D.3    Newby, A.C.4    Baker, A.H.5
  • 118
    • 0032560638 scopus 로고    scopus 로고
    • N-acetyl-cysteine decreases the matrix-degrading capacity of macrophage-derived foam cells: New target for antioxidant therapy?
    • Galis ZS, Asanuma K, Godin D, Meng X. N-acetyl-cysteine decreases the matrix-degrading capacity of macrophage-derived foam cells: new target for antioxidant therapy? Circulation 1998; 97: 2445-53.
    • (1998) Circulation , vol.97 , pp. 2445-2453
    • Galis, Z.S.1    Asanuma, K.2    Godin, D.3    Meng, X.4
  • 119
    • 0037207968 scopus 로고    scopus 로고
    • Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: Significant survival advantage in patients with musculoskeletal side-effects
    • King J, Zhao J, Clingan P, Morris D. Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: significant survival advantage in patients with musculoskeletal side-effects. Anticancer Res 2003; 23: 639-45.
    • (2003) Anticancer Res , vol.23 , pp. 639-645
    • King, J.1    Zhao, J.2    Clingan, P.3    Morris, D.4
  • 120
    • 12144287866 scopus 로고    scopus 로고
    • A randomized phase II feasibility trial of BMS-275291 in patients with early stage breast cancer
    • Miller KD, Saphner TJ, Waterhouse DM, et al. A randomized phase II feasibility trial of BMS-275291 in patients with early stage breast cancer. Clin Cancer Res 2004; 10: 1971-5.
    • (2004) Clin Cancer Res , vol.10 , pp. 1971-1975
    • Miller, K.D.1    Saphner, T.J.2    Waterhouse, D.M.3
  • 121
    • 12144286743 scopus 로고    scopus 로고
    • A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer
    • Rizvi NA, Humphrey JS, Ness EA, et al. A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer. Clin Cancer Res 2004; 10: 1963-70.
    • (2004) Clin Cancer Res , vol.10 , pp. 1963-1970
    • Rizvi, N.A.1    Humphrey, J.S.2    Ness, E.A.3
  • 122
    • 0035916233 scopus 로고    scopus 로고
    • Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
    • Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 2001; 103: 926-33.
    • (2001) Circulation , vol.103 , pp. 926-933
    • Crisby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3    Yano, J.4    Zhu, J.5    Nilsson, J.6
  • 123
    • 0035879774 scopus 로고    scopus 로고
    • Kalela A, Laaksonen R, Lehtimaki T, et al. Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases. Am J Cardiol 2001; 88: 173-5, A176.
    • Kalela A, Laaksonen R, Lehtimaki T, et al. Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases. Am J Cardiol 2001; 88: 173-5, A176.
  • 124
    • 33751171940 scopus 로고    scopus 로고
    • Suppression of RAGE as a basis of simvastatin-dependent plaque stabilization in type 2 diabetes
    • Cuccurullo C, Iezzi A, Fazia ML, et al. Suppression of RAGE as a basis of simvastatin-dependent plaque stabilization in type 2 diabetes. Arterioscler Thromb Vasc Biol 2006; 26: 2716-23.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2716-2723
    • Cuccurullo, C.1    Iezzi, A.2    Fazia, M.L.3
  • 125
    • 0041315638 scopus 로고    scopus 로고
    • The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: Role of glycemic control
    • Cipollone F, Iezzi A, Fazia M, et al. The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control. Circulation 2003; 108: 1070-7.
    • (2003) Circulation , vol.108 , pp. 1070-1077
    • Cipollone, F.1    Iezzi, A.2    Fazia, M.3
  • 126
    • 4644342944 scopus 로고    scopus 로고
    • Thiazolidinediones reduce endothelial expression of receptors for advanced glycation end products
    • Marx N, Walcher D, Ivanova N, et al. Thiazolidinediones reduce endothelial expression of receptors for advanced glycation end products. Diabetes 2004; 53: 2662-8.
    • (2004) Diabetes , vol.53 , pp. 2662-2668
    • Marx, N.1    Walcher, D.2    Ivanova, N.3
  • 127
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • Haffner SM, Greenberg AS, Weston WM, Chen H, Williams K, Freed MI. Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation 2002; 106: 679-84.
    • (2002) Circulation , vol.106 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3    Chen, H.4    Williams, K.5    Freed, M.I.6
  • 128
    • 20444427156 scopus 로고    scopus 로고
    • Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: Principal results of a prospective randomized controlled study (MOSES)
    • Schrader J, Luders S, Kulschewski A, et al. Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES). Stroke 2005; 36: 1218-26.
    • (2005) Stroke , vol.36 , pp. 1218-1226
    • Schrader, J.1    Luders, S.2    Kulschewski, A.3
  • 129
    • 19944428946 scopus 로고    scopus 로고
    • Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: The Losartan Intervention For Endpoint reduction in hypertension study
    • Kizer JR, Dahlof B, Kjeldsen SE, et al. Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: the Losartan Intervention For Endpoint reduction in hypertension study. Hypertension 2005; 45: 46-52.
    • (2005) Hypertension , vol.45 , pp. 46-52
    • Kizer, J.R.1    Dahlof, B.2    Kjeldsen, S.E.3
  • 130
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 145-53.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 131
    • 0028826061 scopus 로고
    • Role of angiotensin II and prostaglandin E2 in regulating cardiac fibroblast collagen turnover
    • Brilla CG, Zhou G, Rupp H, Maisch B, Weber KT. Role of angiotensin II and prostaglandin E2 in regulating cardiac fibroblast collagen turnover. Am J Cardiol 1995; 76: 8D-13D.
    • (1995) Am J Cardiol , vol.76
    • Brilla, C.G.1    Zhou, G.2    Rupp, H.3    Maisch, B.4    Weber, K.T.5
  • 132
    • 12144289317 scopus 로고    scopus 로고
    • Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity
    • Cipollone F, Fazia M, Iezzi A, et al. Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity. Circulation 2004; 109: 1482-8.
    • (2004) Circulation , vol.109 , pp. 1482-1488
    • Cipollone, F.1    Fazia, M.2    Iezzi, A.3
  • 133
    • 8844232710 scopus 로고    scopus 로고
    • Molecular, cellular and functional imaging of atherothrombosis
    • Choudhury RP, Fuster V, Fayad ZA. Molecular, cellular and functional imaging of atherothrombosis. Nat Rev Drug Discov 2004; 3: 913-25.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 913-925
    • Choudhury, R.P.1    Fuster, V.2    Fayad, Z.A.3
  • 134
    • 33644680768 scopus 로고    scopus 로고
    • The vulnerable carotid artery plaque: Current imaging methods and new perspectives
    • Nighoghossian N, Derex L, Douek P. The vulnerable carotid artery plaque: current imaging methods and new perspectives. Stroke 2005; 36: 2764-72.
    • (2005) Stroke , vol.36 , pp. 2764-2772
    • Nighoghossian, N.1    Derex, L.2    Douek, P.3
  • 135
    • 0031983878 scopus 로고    scopus 로고
    • Echo-lucency of computerized ultrasound images of carotid atherosclerotic plaques are associated with increased levels of triglyceride-rich lipoproteins as well as increased plaque lipid content
    • Gronholdt ML, Nordestgaard BG, Wiebe BM, Wilhjelm JE, Sillesen H. Echo-lucency of computerized ultrasound images of carotid atherosclerotic plaques are associated with increased levels of triglyceride-rich lipoproteins as well as increased plaque lipid content. Circulation 1998; 97: 34-40.
    • (1998) Circulation , vol.97 , pp. 34-40
    • Gronholdt, M.L.1    Nordestgaard, B.G.2    Wiebe, B.M.3    Wilhjelm, J.E.4    Sillesen, H.5
  • 136
    • 0033751007 scopus 로고    scopus 로고
    • Echomorphologic and histopathologic characteristics of unstable carotid plaques
    • Tegos TJ, Sohail M, Sabetai MM, et al. Echomorphologic and histopathologic characteristics of unstable carotid plaques. Am J Neuroradiol 2000; 21: 1937-44.
    • (2000) Am J Neuroradiol , vol.21 , pp. 1937-1944
    • Tegos, T.J.1    Sohail, M.2    Sabetai, M.M.3
  • 137
    • 0031752671 scopus 로고    scopus 로고
    • Hypoechoic plaque at US of the carotid artery: An independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study
    • Polak JF, Shemanski L, O'Leary DH, et al. Hypoechoic plaque at US of the carotid artery: an independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study. Radiology 1998; 208: 649-54.
    • (1998) Radiology , vol.208 , pp. 649-654
    • Polak, J.F.1    Shemanski, L.2    O'Leary, D.H.3
  • 138
    • 14344270557 scopus 로고    scopus 로고
    • Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: The tromso study
    • Mathiesen EB, Bonaa KH, Joakimsen O. Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: the tromso study. Circulation 2001; 103: 2171-5.
    • (2001) Circulation , vol.103 , pp. 2171-2175
    • Mathiesen, E.B.1    Bonaa, K.H.2    Joakimsen, O.3
  • 140
    • 0033816454 scopus 로고    scopus 로고
    • Reproducibility of computer-quantified carotid plaque echogenicity: Can we overcome the subjectivity?
    • Sabetai MM, Tegos TJ, Nicolaides AN, Dhanjil S, Pare GJ, Stevens JM. Reproducibility of computer-quantified carotid plaque echogenicity: can we overcome the subjectivity? Stroke 2000; 31: 2189-96.
    • (2000) Stroke , vol.31 , pp. 2189-2196
    • Sabetai, M.M.1    Tegos, T.J.2    Nicolaides, A.N.3    Dhanjil, S.4    Pare, G.J.5    Stevens, J.M.6
  • 141
    • 4043063507 scopus 로고    scopus 로고
    • Carotid plaque echolucency increases the risk of stroke in carotid stenting: The Imaging in Carotid Angioplasty and Risk of Stroke (ICAROS) study
    • Biasi GM, Froio A, Diethrich EB, et al. Carotid plaque echolucency increases the risk of stroke in carotid stenting: the Imaging in Carotid Angioplasty and Risk of Stroke (ICAROS) study. Circulation 2004; 110: 756-62.
    • (2004) Circulation , vol.110 , pp. 756-762
    • Biasi, G.M.1    Froio, A.2    Diethrich, E.B.3
  • 142
    • 54849410615 scopus 로고    scopus 로고
    • Association of carotid artery atherosclerosis with circulating biomarkers of extracellular matrix remodeling: The Framingham Offspring Study
    • Romero JR, Vasan RS, Beiser AS, et al. Association of carotid artery atherosclerosis with circulating biomarkers of extracellular matrix remodeling: the Framingham Offspring Study. J Stroke Cerebrovasc Dis 2008; 17: 412-7.
    • (2008) J Stroke Cerebrovasc Dis , vol.17 , pp. 412-417
    • Romero, J.R.1    Vasan, R.S.2    Beiser, A.S.3
  • 143
    • 0033531215 scopus 로고    scopus 로고
    • Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group
    • O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK, Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999; 340: 14-22.
    • (1999) N Engl J Med , vol.340 , pp. 14-22
    • O'Leary, D.H.1    Polak, J.F.2    Kronmal, R.A.3    Manolio, T.A.4    Burke, G.L.5    Wolfson Jr., S.K.6
  • 144
    • 33846609195 scopus 로고    scopus 로고
    • Prediction of clinical cardiovascular events with carotid intima-media thickness: A systematic review and meta-analysis
    • Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 2007; 115: 459-67.
    • (2007) Circulation , vol.115 , pp. 459-467
    • Lorenz, M.W.1    Markus, H.S.2    Bots, M.L.3    Rosvall, M.4    Sitzer, M.5
  • 145
    • 0037469182 scopus 로고    scopus 로고
    • Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted to alpha(v)-integrins
    • Leong-Poi H, Christiansen J, Klibanov AL, Kaul S, Lindner JR. Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted to alpha(v)-integrins. Circulation 2003; 107: 455-60.
    • (2003) Circulation , vol.107 , pp. 455-460
    • Leong-Poi, H.1    Christiansen, J.2    Klibanov, A.L.3    Kaul, S.4    Lindner, J.R.5
  • 146
    • 0038179627 scopus 로고    scopus 로고
    • Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging
    • Kooi ME, Cappendijk VC, Cleutjens KB, et al. Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging. Circulation 2003; 107: 2453-8.
    • (2003) Circulation , vol.107 , pp. 2453-2458
    • Kooi, M.E.1    Cappendijk, V.C.2    Cleutjens, K.B.3
  • 147
    • 0342445413 scopus 로고    scopus 로고
    • In vivo visualization of gene expression using magnetic resonance imaging
    • Louie AY, Huber MM, Ahrens ET, et al. In vivo visualization of gene expression using magnetic resonance imaging. Nat Biotechnol 2000; 18: 321-5.
    • (2000) Nat Biotechnol , vol.18 , pp. 321-325
    • Louie, A.Y.1    Huber, M.M.2    Ahrens, E.T.3
  • 148
    • 33646396223 scopus 로고    scopus 로고
    • 18F-FDG accumulation in atherosclerosis: Use of CT and MR co-registration of thoracic and carotid arteries
    • Okane K, Ibaraki M, Toyoshima H, et al. 18F-FDG accumulation in atherosclerosis: use of CT and MR co-registration of thoracic and carotid arteries. Eur J Nucl Med Mol Imaging 2006; 33: 589-94.
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 589-594
    • Okane, K.1    Ibaraki, M.2    Toyoshima, H.3
  • 149
    • 33750445273 scopus 로고    scopus 로고
    • In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients
    • Tawakol A, Migrino RQ, Bashian GG, et al. In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients. J Am Coll Cardiol 2006; 48: 1818-24.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1818-1824
    • Tawakol, A.1    Migrino, R.Q.2    Bashian, G.G.3
  • 150
    • 34547954508 scopus 로고    scopus 로고
    • Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: Implications for atherosclerosis therapy trials
    • Rudd JH, Myers KS, Bansilal S, et al. Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials. J Am Coll Cardiol 2007; 50: 892-6.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 892-896
    • Rudd, J.H.1    Myers, K.S.2    Bansilal, S.3
  • 151
    • 33750448287 scopus 로고    scopus 로고
    • Simvastatin attenuates plaque inflammation: Evaluation by fluorodeoxyglucose positron emission tomography
    • Tahara N, Kai H, Ishibashi M, et al. Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography. J Am Coll Cardiol 2006; 48: 1825-31.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1825-1831
    • Tahara, N.1    Kai, H.2    Ishibashi, M.3
  • 152
    • 34250784515 scopus 로고    scopus 로고
    • Targeting of matrix metalloproteinase activation for noninvasive detection of vulnerable atherosclerotic lesions
    • Hartung D, Schafers M, Fujimoto S, et al. Targeting of matrix metalloproteinase activation for noninvasive detection of vulnerable atherosclerotic lesions. Eur J Nucl Med Mol Imaging 2007; 34(Suppl 1): S1-8.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , Issue.SUPPL. 1
    • Hartung, D.1    Schafers, M.2    Fujimoto, S.3
  • 153
    • 0034954524 scopus 로고    scopus 로고
    • In vivo molecular target assessment of matrix metalloproteinase inhibition
    • Bremer C, Tung CH, Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 2001; 7: 743-8.
    • (2001) Nat Med , vol.7 , pp. 743-748
    • Bremer, C.1    Tung, C.H.2    Weissleder, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.