Altered expression balance of matrix metalloproteinases and their inhibitors in human carotid plaque disruption: Results of quantitative tissue analysis using real-time RT-PCR method

Atherosclerosis

Volumn 185, Issue 1, 2006, Pages 165-172

  Higashikata, Takeo ^a   Yamagishi, Masakazu ^a   Higashi, Toshio ^a   Nagata, Izumi ^a   Iihara, Koji ^a   Miyamoto, Susumu ^a   Ishibashi Ueda, Hatsue ^a   Nagaya, Noritoshi ^a   Iwase, Takashi ^a   Tomoike, Hitonobu ^a   Sakamoto, Aiji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Atherosclerosis; Extracellular matrix; Matrix metalloproteinases; Plaque disruption; Tissue factor pathway inhibitor 2; Tissue inhibitor of metalloproteinases

Indexed keywords

GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; PLACENTA PROTEIN 5; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ADULT; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR RISK; CAROTID ENDARTERECTOMY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; CAROTID ARTERIES; CAROTID ARTERY DISEASES; ENDARTERECTOMY, CAROTID; GENE EXPRESSION; GENETIC MARKERS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MATRIX METALLOPROTEINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 30944456938     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2005.05.039     Document Type: Article

References (33)

1. E. Falk, P.K. Shah, and V. Fuster Coronary plaque disruption Circulation 92 1995 657 671
2. S. Carr, A. Farb, and W.H. Pearce Atherosclerotic plaque rupture in symptomatic carotid artery stenosis J Vasc Surg 23 1996 755 765
3. P. Libby Inflammation in atherosclerosis Nature 420 2002 868 874
4. C.M. Dollery, J.R. McEwan, and A.M. Henney Matrix metalloproteinases and cardiovascular disease Circ Res 77 1995 863 868
5. Z.S. Galis, and J.J. Khatri Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly Circ Res 90 2002 251 262
6. H. Nagase Activation mechanisms of matrix metalloproteinases Biol Chem 378 1997 151 160
7. M.P. Herman, G.K. Sukhova, and W. Kisiel Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis J Clin Invest 107 2001 1117 1126
8. R.P. Fabunmi, G.K. Sukhova, and S. Sugiyama Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability Circ Res 83 1998 270 278
9. Z.S. Galis, G.K. Sukhova, and M.W. Lark Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques J Clin Invest 94 1994 2493 2503
10. K. Brew, D. Dinakarpandian, and H. Nagase Tissue inhibitors of metalloproteinases: evolution, structure and function Biochim Biophys Acta 1477 2000 267 283
11. J.B. Knox, G.K. Sukhova, and A.D. Whittemore Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases Circulation 95 1997 205 212
12. M.D. Sternlicht, and Z. Werb How matrix metalloproteinases regulate cell behavior Annu Rev Cell Dev Biol 17 2001 463 516
13. T. Higashikata, M. Yamagishi, and H. Sasaki Application of real-time RT-PCR to quantifying gene expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human abdominal aortic aneurysm Atherosclerosis 177 2004 353 360
14. F.D. Kolodgie, A.P. Burke, and A. Farb The thin-cap fibroatheroma: a type of vulnerable plaque, the major precursor lesion to acute coronary syndrome Curr Opin Cardiol 16 2001 285 292
15. P. Schoenhagen, K.M. Ziada, and S.R. Kapadia Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study Circulation 101 2000 598 603
16. D.L. Brwon, M.S. Hibbs, and M. Kearney Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina Circulation 91 1995 2125 2131
17. I.M. Loftus, A.R. Naylor, and S. Goodall Increased matrix metalloproteinase-9 activity in unstable carotid plaques. A potential role in acute plaque disruption Stroke 31 2000 40 47
18. S.T. Nikkari, K.D. O'Brien, and M. Ferguson Intestinal collagenase (MMP-1) expression in human carotid atherosclerosis Circulation 92 1995 1393 1398
19. G.K. Sukhova, U. Schonbeck, and E. Rabkin Evidence for increased collagenolysis by intersitial collagenases-1 and -3 in vulnerable atheromatous plaques Circulation 99 1999 2503 2509
20. H. Sato, T. Takino, and Y. Okada A matrix metalloproteinase expressed on the surface of invasive tumor cells Nature 370 1994 61 65
21. J. Silence, D. Collen, and H.R. Lijnen Reduced atherosclerotic plaque but enhanced aneurysm formation in mice with inactivation of the tissue inhibitor of metalloproteinase-1 (TIMP-1) gene Circ Res 90 2002 897 903
22. M. Rouis, C. Adamy, and N. Duverger Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinase-1 reduces atherosclerotic lesions in apolipoprotein E-deficient mice Circulation 100 1999 533 540
23. K. Morishige, H. Shimokawa, and Y. Matsumoto Overexpression of matrix metalloproteinase-9 promotes intravascular thrombus formation in porcine coronary arteries in vivo Cardiovasc Res 57 2003 572 585
24. M. Yamagishi, M. Terashima, and K. Awano Morphology of vulnerable coronary plaque: insights from follow-up of patients examined by intravascular ultrasound before an acute coronary syndrome J Am Coll Cardiol 35 2000 106 111
25. S. Higo, S. Nanto, and T. Higashikata Impact of altered expression balance of matrix metalloproteinases and tissue inhibitor of metalloproteinases genes on coronary plaque rupture: results from quantitative tissue analysis using real-time reverse transcriptase-polymerase chain reaction method (abstr) J Am Coll Cardiol 43 Suppl. A 2004 257A
26. G. Rioufol, G. Finet, and I. Ginon Multiple atherosclerotic plaque rupture in acute coronary syndrome. A three-vessel intravascular ultrasound study Circulation 106 2002 804 808
27. P. Schoenhagen, G.W. Stone, and S.E. Nissen Coronary plaque morphology and frequency of ulceration distant from culprit lesions in patients with unstable and stable presentation Arterioscler Thromb Vasc Biol 23 2003 1895 1900
28. J. Johnson, A. George, and C. Newby Matrix metalloproteinase-9 and -12 have opposite effects on atherosclerotic plaque stability (abstr) Atherosclerosis 4 Suppl. 2003 196
29. C.M. Dollery, C.A. Owen, and G.K. Sukhova Neutrophil elastase in human atherosclerotic plaques. Production by macrophages Circulation 107 2003 2829 2836
30. J.R. Woessner Quantification of matrix metalloproteinases in tissue samples Methods Enzymol 248 1995 510 528
31. R. Blindt, F. Vogt, and D. Lamby Characterization of differential gene expression in quiescent and invasive human arterial smooth muscle cells J Vasc Res 39 2002 340 352
32. M. Yamagishi, T. Higashikata, and T. Higashi Sustained upregulation of chemokine and its receptor genes associated with matrix metalloproteinase overexpression in human carotid plaque rupture: results from a quantitative study with real-time reverse transcriptase-polymerase chain reaction method (abstr) J Am Coll Cardiol 43 Suppl. 2004 497A
33. A.J. Chase, M. Bond, and M.F. Crook Role of nuclear NF-κB activation in metalloproteinase-1 -3 and -9 secretion by human macrophages in vitro and rabbit form cells produced in vivo Arterioscler Thromb Vasc Biol 22 2002 765 771