Selective enhancement of nutrient-induced insulin secretion by ATP-sensitive K+ channel-blocking imidazolines

Journal of Pharmacology and Experimental Therapeutics

Volumn 331, Issue 3, 2009, Pages 1033-1041

  Hatlapatka, Kathrin ^a   Wienbergen, Antje ^a   Kühne, Claudia ^a   Jörns, Anne ^b   Willenborg, Michael ^a   Rustenbeck, Ingo ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 (IMIDAZOLIN 2 YL) 1 PHENYLIDOLE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ALINIDINE; EFAROXAN; IMIDAZOLINE; PHENTOLAMINE; RX 871024; SULFONYLUREA RECEPTOR; UNCLASSIFIED DRUG; ABC TRANSPORTER; CALCIUM; DRUG RECEPTOR; GLUCOSE; IMIDAZOLINE DERIVATIVE; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; INSULIN RELEASE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUTRIENT; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG ANTAGONISM; GENETICS; METABOLISM; MOUSE MUTANT; PANCREAS ISLET; PATCH CLAMP; SECRETION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CALCIUM; CELL MEMBRANE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; IMIDAZOLINES; INSULIN; ISLETS OF LANGERHANS; KATP CHANNELS; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG;

EID: 73349130452     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.152751     Document Type: Article

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