메뉴 건너뛰기




Volumn 45, Issue 11, 1996, Pages 1610-1618

Imidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinery

Author keywords

[No Author keywords available]

Indexed keywords

BRIMONIDINE; CALCIUM ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; IDAZOXAN; IMIDAZOLINE DERIVATIVE; INSULIN; PHENTOLAMINE; POTASSIUM CHANNEL; PROTEIN KINASE C; RX 871024; UNCLASSIFIED DRUG;

EID: 0029973985     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.11.1610     Document Type: Article
Times cited : (97)

References (46)
  • 2
    • 0027941213 scopus 로고
    • Protein phosphorylation and beta-cell function
    • Ashcroft SJH: Protein phosphorylation and beta-cell function. Diabetologia 37:S21-S29, 1994
    • (1994) Diabetologia , vol.37
    • Ashcroft, S.J.H.1
  • 3
    • 0028205382 scopus 로고
    • Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells
    • Åmmälä C, Eliasson L, Bokvist K, Berggren PO, Honkanen RE, Sjöholm Å, Rorsman P: Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells. Proc Natl Acad Sci USA 91:4343-4347, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4343-4347
    • Åmmälä, C.1    Eliasson, L.2    Bokvist, K.3    Berggren, P.O.4    Honkanen, R.E.5    Sjöholm, Å.6    Rorsman, P.7
  • 5
    • 0027933317 scopus 로고
    • Regulation of insulin secretion: Role of second messengers
    • Howell SL, Jones PM, Persuad SJ: Regulation of insulin secretion: role of second messengers. Diabetologia 37:S30-S35, 1994
    • (1994) Diabetologia , vol.37
    • Howell, S.L.1    Jones, P.M.2    Persuad, S.J.3
  • 6
    • 0014668997 scopus 로고
    • Role of adrenergic receptors in glucose-induced insulin secretion in man
    • Cerasi E, Efendić S, Luft R: Role of adrenergic receptors in glucose-induced insulin secretion in man. Lancet ii:301-302, 1969
    • (1969) Lancet , vol.2 , pp. 301-302
    • Cerasi, E.1    Efendić, S.2    Luft, R.3
  • 7
    • 0015867792 scopus 로고
    • Effect of blockade of the alpha-adrenergic receptors on insulin response to glucose infusion in prediabetic subjects
    • Efendić S, Cerasi E, Luft R: Effect of blockade of the alpha-adrenergic receptors on insulin response to glucose infusion in prediabetic subjects. Acta Endocrinol 74:542-547, 1973
    • (1973) Acta Endocrinol , vol.74 , pp. 542-547
    • Efendić, S.1    Cerasi, E.2    Luft, R.3
  • 8
    • 0016829106 scopus 로고
    • Effect of phentolamine and preperfusion with glucose on insulin release from the isolated perfused pancreas from fasted and fed rats
    • Efendić S, Cerasi E, Luft R: Effect of phentolamine and preperfusion with glucose on insulin release from the isolated perfused pancreas from fasted and fed rats. Diabetologia 11:407-410, 1975
    • (1975) Diabetologia , vol.11 , pp. 407-410
    • Efendić, S.1    Cerasi, E.2    Luft, R.3
  • 9
    • 0023796866 scopus 로고
    • Alpha 2-adrenoceptor blockade does not enhance glucose-induced insulin release in normal subjects or patients with noninsulin-dependent diabetes
    • Östenson CG, Pigon J, Doxey JC, Efendić S: Alpha 2-adrenoceptor blockade does not enhance glucose-induced insulin release in normal subjects or patients with noninsulin-dependent diabetes. J Clin Endocrinol Metab 67:1054-1059, 1988
    • (1988) J Clin Endocrinol Metab , vol.67 , pp. 1054-1059
    • Östenson, C.G.1    Pigon, J.2    Doxey, J.C.3    Efendić, S.4
  • 10
    • 0024469031 scopus 로고
    • Alpha-adrenoreceptors and insulin release from pancreatic islets of normal and diabetic rats
    • Östenson CG, Cattaneo AG, Doxey JC, Efendić S: Alpha-adrenoreceptors and insulin release from pancreatic islets of normal and diabetic rats. Am J Physiol 257:E439-E443, 1989
    • (1989) Am J Physiol , vol.257
    • Östenson, C.G.1    Cattaneo, A.G.2    Doxey, J.C.3    Efendić, S.4
  • 11
    • 0024444239 scopus 로고
    • An insulin-releasing property of imidazoline derivatives is not limited to compounds that block alpha-adrenoceptors
    • Schulz A, Hasselblatt A: An insulin-releasing property of imidazoline derivatives is not limited to compounds that block alpha-adrenoceptors. Naunyn-Schmiedeberg's Arch Pharmacol 340:321-327, 1989
    • (1989) Naunyn-Schmiedeberg's Arch Pharmacol , vol.340 , pp. 321-327
    • Schulz, A.1    Hasselblatt, A.2
  • 12
    • 0024836117 scopus 로고
    • Dual action of clonidine on insulin release: Suppression, but stimulation when alpha 2-adrenoceptors are blocked
    • Schulz A, Hasselblatt A: Dual action of clonidine on insulin release: suppression, but stimulation when alpha 2-adrenoceptors are blocked. Naunyn-Schmiedeberg's Arch Pharmacol 340:712-714, 1989
    • (1989) Naunyn-Schmiedeberg's Arch Pharmacol , vol.340 , pp. 712-714
    • Schulz, A.1    Hasselblatt, A.2
  • 14
    • 0025148602 scopus 로고
    • + channels in mouse pancreatic β-cells
    • + channels in mouse pancreatic β-cells. Br J Pharmacol 101:115-120, 1990
    • (1990) Br J Pharmacol , vol.101 , pp. 115-120
    • Plant, T.D.1    Henquin, J.C.2
  • 17
    • 0025173880 scopus 로고
    • Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels
    • Chan SLF, Morgan NG: Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels. Eur J Pharmacol 176:97-101, 1990
    • (1990) Eur J Pharmacol , vol.176 , pp. 97-101
    • Chan, S.L.F.1    Morgan, N.G.2
  • 18
    • 0025912184 scopus 로고
    • Mechanisms involved in stimulation of insulin secretion by the hypoglycapmic alpha-adrenergic antagonist, DG-5128
    • Chan SLF, Stillings MR, Morgan NG: Mechanisms involved in stimulation of insulin secretion by the hypoglycapmic alpha-adrenergic antagonist, DG-5128. Biochem Biophys Res Comm 176:1545-1551, 1991
    • (1991) Biochem Biophys Res Comm , vol.176 , pp. 1545-1551
    • Chan, S.L.F.1    Stillings, M.R.2    Morgan, N.G.3
  • 19
    • 0026507335 scopus 로고
    • Comparison of the affects of efaroxan and glibenclamide on plasma glucose and insulin levels in rats
    • Berridge TL, Doxey JC, Roach AG: Comparison of the affects of efaroxan and glibenclamide on plasma glucose and insulin levels in rats. Eur J Pharmacol 213:213-218, 1992
    • (1992) Eur J Pharmacol , vol.213 , pp. 213-218
    • Berridge, T.L.1    Doxey, J.C.2    Roach, A.G.3
  • 20
    • 0027144034 scopus 로고
    • Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080
    • Brown CA, Chan SLF, Stilling MR, Smith SA, Morgan NG: Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080. Br J Pharmacol 110:1017-1022, 1993
    • (1993) Br J Pharmacol , vol.110 , pp. 1017-1022
    • Brown, C.A.1    Chan, S.L.F.2    Stilling, M.R.3    Smith, S.A.4    Morgan, N.G.5
  • 21
    • 0022577987 scopus 로고
    • Differences in long-term effects of L-glutamine and D-glucose on insulin release from rat pancreatic islets
    • Östenson CG, Grill V: Differences in long-term effects of L-glutamine and D-glucose on insulin release from rat pancreatic islets. Mol Cell Endocrinol 45:215-221, 1986
    • (1986) Mol Cell Endocrinol , vol.45 , pp. 215-221
    • Östenson, C.G.1    Grill, V.2
  • 23
    • 0019038173 scopus 로고
    • Neutral carrier ion-selective microelectrodes for measurements of intracellular free calcium
    • Tsien RY, Rink TJ: Neutral carrier ion-selective microelectrodes for measurements of intracellular free calcium. Biochim Biophys Acta 599:623-638, 1980
    • (1980) Biochim Biophys Acta , vol.599 , pp. 623-638
    • Tsien, R.Y.1    Rink, T.J.2
  • 25
    • 0024791536 scopus 로고
    • A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic β-cells
    • Corkey BE, Glennon MC, Chen RS, Deeney JT, Matschinsky FM, Prentki M: A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic β-cells. J Biol Chem 264:21608-21612, 1989
    • (1989) J Biol Chem , vol.264 , pp. 21608-21612
    • Corkey, B.E.1    Glennon, M.C.2    Chen, R.S.3    Deeney, J.T.4    Matschinsky, F.M.5    Prentki, M.6
  • 26
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ: Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:85-100, 1981
    • (1981) Pflügers Arch , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 27
    • 0023795593 scopus 로고
    • Muscarinic activation of ionic currents measured by a new whole-cell recording method
    • Horn DR, Marty A: Muscarinic activation of ionic currents measured by a new whole-cell recording method. J Gen Physiol 92:145-159, 1988
    • (1988) J Gen Physiol , vol.92 , pp. 145-159
    • Horn, D.R.1    Marty, A.2
  • 28
    • 0015049463 scopus 로고
    • Pharmacological estimation of drug-receptor dissociation constants: Statistical evaluation. I. Agonists
    • Parker RB, Waud DR: Pharmacological estimation of drug-receptor dissociation constants: statistical evaluation. I. Agonists. J Pharmacol Exp Ther 177:1-12, 1971
    • (1971) J Pharmacol Exp Ther , vol.177 , pp. 1-12
    • Parker, R.B.1    Waud, D.R.2
  • 29
    • 0027535908 scopus 로고
    • Stimulation of insulin secretion by imidazoline compounds is not due to interaction with non-adrenoceptor idazoxan binding sites
    • Brown CA, Loweth AC, Smith SA, Morgan NG: Stimulation of insulin secretion by imidazoline compounds is not due to interaction with non-adrenoceptor idazoxan binding sites. Br J Pharmacol 108:312-317, 1993
    • (1993) Br J Pharmacol , vol.108 , pp. 312-317
    • Brown, C.A.1    Loweth, A.C.2    Smith, S.A.3    Morgan, N.G.4
  • 31
    • 0026062301 scopus 로고
    • An imidazoline-specific mechanism for the hypotensive effect of clonidine: A study with yohimbine and idazoxan
    • Tibirica E, Feldman J, Mermet C, Gonon F, Bonsquet P: An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan. J Pharmacol Exp Ther 256:606-613, 1991
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 606-613
    • Tibirica, E.1    Feldman, J.2    Mermet, C.3    Gonon, F.4    Bonsquet, P.5
  • 32
    • 0026766318 scopus 로고
    • Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic β-cells
    • Rorsman P, Ämmälä C, Berggren PO, Bokvist K, Larsson O: Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic β-cells. EMBO J 8:2877-2884, 1992
    • (1992) EMBO J , vol.8 , pp. 2877-2884
    • Rorsman, P.1    Ämmälä, C.2    Berggren, P.O.3    Bokvist, K.4    Larsson, O.5
  • 34
    • 0024550448 scopus 로고
    • Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C
    • Kobayashi E, Nakano H, Morimoto M, Tamaoki T: Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem Biophys Res Comm 159:548-553, 1980
    • (1980) Biochem Biophys Res Comm , vol.159 , pp. 548-553
    • Kobayashi, E.1    Nakano, H.2    Morimoto, M.3    Tamaoki, T.4
  • 35
    • 0023909111 scopus 로고
    • Inhibition of cAMP-dependent protein kinase by adenosine cyclic 3′-,5′-phosphorodithioate, a second cAMP antagonist
    • Botelho LH, Webster LC, Rothermel JD, Baraniak J, Stec WJ: Inhibition of cAMP-dependent protein kinase by adenosine cyclic 3′-,5′-phosphorodithioate, a second cAMP antagonist. J Biol Chem 263:5301-5305, 1988
    • (1988) J Biol Chem , vol.263 , pp. 5301-5305
    • Botelho, L.H.1    Webster, L.C.2    Rothermel, J.D.3    Baraniak, J.4    Stec, W.J.5
  • 36
    • 0025248571 scopus 로고
    • Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromo- Cytoma cells
    • Chijima T, Mishima A, Hagiwara M, Sano M, Hayashi K, Inoue T, Naito K, Toshioka T, Hidaka H: Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromo- cytoma cells. J Biol Chem 265:5267-5272, 1990
    • (1990) J Biol Chem , vol.265 , pp. 5267-5272
    • Chijima, T.1    Mishima, A.2    Hagiwara, M.3    Sano, M.4    Hayashi, K.5    Inoue, T.6    Naito, K.7    Toshioka, T.8    Hidaka, H.9
  • 37
    • 0024456533 scopus 로고
    • Effects of protein kinase C activation on the regulation of the stimulus-secreting coupling in pancreatic β-cells
    • Arkhammar P, Nilsson T, Welsh M, Welsh N, Berggren PO: Effects of protein kinase C activation on the regulation of the stimulus-secreting coupling in pancreatic β-cells. Biochem J 264:207-215, 1989
    • (1989) Biochem J , vol.264 , pp. 207-215
    • Arkhammar, P.1    Nilsson, T.2    Welsh, M.3    Welsh, N.4    Berggren, P.O.5
  • 40
    • 0025265242 scopus 로고
    • + channels in mouse pancreatic beta-cells by external tetraethylammonium and quinine
    • + channels in mouse pancreatic beta-cells by external tetraethylammonium and quinine. J Physiol 423:337-342, 1990
    • (1990) J Physiol , vol.423 , pp. 337-342
    • Bokvist, K.1    Rorsman, P.2    Smith, P.A.3
  • 41
    • 0025562585 scopus 로고
    • Glucose-stimulated insulin secretion is not dependent on activation of protein kinase A
    • Persaud SJ, Jones PM, Howell SL: Glucose-stimulated insulin secretion is not dependent on activation of protein kinase A. Biochem Biophys Res Comm 173:833-839, 1990
    • (1990) Biochem Biophys Res Comm , vol.173 , pp. 833-839
    • Persaud, S.J.1    Jones, P.M.2    Howell, S.L.3
  • 42
    • 0022402704 scopus 로고
    • Inhibition by 1-(5-isoquinoline-sylfonyl)-2-methylpiperazine (H-7) of protein kinase C activity and insulin release in pancreatic islets
    • Malaisse WJ, Sener A: Inhibition by 1-(5-isoquinoline-sylfonyl)-2-methylpiperazine (H-7) of protein kinase C activity and insulin release in pancreatic islets. IRCS Med Sci 13:1239-1240, 1985
    • (1985) IRCS Med Sci , vol.13 , pp. 1239-1240
    • Malaisse, W.J.1    Sener, A.2
  • 43
    • 0023854046 scopus 로고
    • Effects of a phorbol ester and clomiphene on protein phosphorylation and insulin secretion in rat pancreatic islets
    • Hughes SJ, Ashcroft SJH: Effects of a phorbol ester and clomiphene on protein phosphorylation and insulin secretion in rat pancreatic islets. Biochem J 249:825-830, 1988
    • (1988) Biochem J , vol.249 , pp. 825-830
    • Hughes, S.J.1    Ashcroft, S.J.H.2
  • 44
    • 0023008869 scopus 로고
    • New alpha 2-adrenergic blocker (DG-5128) improves insulin secretion and in vivo glucose disposal in NIDDM patients
    • Kashiwagi A, Harono Y, Suzuki M, Kojima H, Harada M, Nishio Y, Shigeta Y: New alpha 2-adrenergic blocker (DG-5128) improves insulin secretion and in vivo glucose disposal in NIDDM patients. Diabetes 35:1085-1089, 1986
    • (1986) Diabetes , vol.35 , pp. 1085-1089
    • Kashiwagi, A.1    Harono, Y.2    Suzuki, M.3    Kojima, H.4    Harada, M.5    Nishio, Y.6    Shigeta, Y.7
  • 45
    • 0023544616 scopus 로고
    • Studies of midaglizole (DG-5128): A new type of oral hypoglycemic drug in healthy subject
    • Kawazu S, Suzuki M, Negishi K, Watanabe T, Ishii J: Studies of midaglizole (DG-5128): a new type of oral hypoglycemic drug in healthy subject. Diabetes 36:216-220, 1987
    • (1987) Diabetes , vol.36 , pp. 216-220
    • Kawazu, S.1    Suzuki, M.2    Negishi, K.3    Watanabe, T.4    Ishii, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.