A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3

Journal of Experimental Medicine

Volumn 206, Issue 12, 2009, Pages 2747-2760

  Yamamoto, Masahiro ^a,b   Standley, Daron M ^b   Takashima, Seiji ^a   Saiga, Hiroyuki ^a,b   Okuyama, Megumi ^a,b   Kayama, Hisako ^a,b   Kubo, Emi ^a   Ito, Hiroshi ^a   Takaura, Mutsumi ^a   Matsuda, Tadashi ^c   Soldati Favre, Dominique ^d   Takeda, Kiyoshi ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; INTERLEUKIN 12P40; INTERLEUKIN 6; PHOSPHOTRANSFERASE; PROTEIN KINASE; PROTEIN KINASE ROP16; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TYROSINE; UNCLASSIFIED DRUG; IL12B PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; PROTOZOAL PROTEIN; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GENE ACTIVATION; GENE OVEREXPRESSION; MACROPHAGE; MAMMAL CELL; NONHUMAN; PARASITE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTOZOAL GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM; STRAIN DIFFERENCE; TOXOPLASMA GONDII; ANIMAL; CERCOPITHECUS; GENETICS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; MOUSE; PARASITOLOGY; PERITONEUM MACROPHAGE; SPECIES DIFFERENCE; TOXOPLASMA; TOXOPLASMOSIS; VERO CELL;

AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; PHOSPHOTRANSFERASES; PROTOZOAN PROTEINS; SPECIES SPECIFICITY; STAT3 TRANSCRIPTION FACTOR; TOXOPLASMA; TOXOPLASMOSIS; VERO CELLS;

EID: 73349119704     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20091703     Document Type: Article

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