메뉴 건너뛰기




Volumn 48, Issue 1, 2010, Pages 96-105

Ion-channel mRNA-expression profiling: Insights into cardiac remodeling and arrhythmic substrates

Author keywords

Afterdepolarizations; Antiarrhythmic drug therapy; Biophysics; Brugada Syndrome; Cardiac arrhythmia mechanisms; Cardiomyopathy; Congenital arrhythmia syndromes; Electrocardiogram; Electrophysiology; Genomics; Ion currents; Long QT syndrome; Mathematical modeling

Indexed keywords

AMIODARONE; COMPLEMENTARY DNA; ION CHANNEL; MESSENGER RNA; PHOSPHOLAMBAN; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCND2; SODIUM CHANNEL; SODIUM CHANNEL NAV1.4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IRX3; TRANSCRIPTION FACTOR IRX5; UNCLASSIFIED DRUG;

EID: 73249131192     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.07.016     Document Type: Review
Times cited : (36)

References (58)
  • 1
    • 0035163686 scopus 로고    scopus 로고
    • Arrhythmogenic ionic remodeling: adaptive responses with maladaptive consequences
    • Nattel S., Khairy P., and Schram G. Arrhythmogenic ionic remodeling: adaptive responses with maladaptive consequences. Trends Cardiovasc. Med. 11 7 (2001) 295-301
    • (2001) Trends Cardiovasc. Med. , vol.11 , Issue.7 , pp. 295-301
    • Nattel, S.1    Khairy, P.2    Schram, G.3
  • 2
    • 34248595219 scopus 로고    scopus 로고
    • Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation
    • Nattel S., Maguy A., Le Bouter S., and Yeh Y.H. Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation. Physiol. Rev. 87 2 (2007) 425-456
    • (2007) Physiol. Rev. , vol.87 , Issue.2 , pp. 425-456
    • Nattel, S.1    Maguy, A.2    Le Bouter, S.3    Yeh, Y.H.4
  • 4
  • 5
    • 59449097258 scopus 로고    scopus 로고
    • Remodelling of cardiac repolarization: how homeostatic responses can lead to arrhythmogenesis
    • Michael G., Xiao L., Qi X.Y., Dobrev D., and Nattel S. Remodelling of cardiac repolarization: how homeostatic responses can lead to arrhythmogenesis. Cardiovasc. Res. 81 3 (2009) 491-499
    • (2009) Cardiovasc. Res. , vol.81 , Issue.3 , pp. 491-499
    • Michael, G.1    Xiao, L.2    Qi, X.Y.3    Dobrev, D.4    Nattel, S.5
  • 8
    • 33745834389 scopus 로고    scopus 로고
    • Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications
    • Seo D., Ginsburg G.S., and Goldschmidt-Clermont P.J. Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications. J. Am. Coll. Cardiol. 48 2 (2006) 227-235
    • (2006) J. Am. Coll. Cardiol. , vol.48 , Issue.2 , pp. 227-235
    • Seo, D.1    Ginsburg, G.S.2    Goldschmidt-Clermont, P.J.3
  • 9
    • 0037123990 scopus 로고    scopus 로고
    • Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function
    • Schram G., Pourrier M., Melnyk P., and Nattel S. Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function. Circ. Res. 90 9 (2002) 939-950
    • (2002) Circ. Res. , vol.90 , Issue.9 , pp. 939-950
    • Schram, G.1    Pourrier, M.2    Melnyk, P.3    Nattel, S.4
  • 10
    • 35349025904 scopus 로고    scopus 로고
    • Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes
    • Antzelevitch C. Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes. Am. J. Physiol, Heart Circ. Physiol. 293 4 (2007) H2024-H2038
    • (2007) Am. J. Physiol, Heart Circ. Physiol. , vol.293 , Issue.4
    • Antzelevitch, C.1
  • 11
    • 31444444911 scopus 로고    scopus 로고
    • Regional variation in mRNA transcript abundance within the ventricular wall
    • Rosati B., Grau F., and McKinnon D. Regional variation in mRNA transcript abundance within the ventricular wall. J. Mol. Cell. Cardiol. 40 2 (2006) 295-302
    • (2006) J. Mol. Cell. Cardiol. , vol.40 , Issue.2 , pp. 295-302
    • Rosati, B.1    Grau, F.2    McKinnon, D.3
  • 12
    • 0028361109 scopus 로고
    • Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats
    • Dixon J.E., and McKinnon D. Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats. Circ. Res. 75 2 (1994) 252-260
    • (1994) Circ. Res. , vol.75 , Issue.2 , pp. 252-260
    • Dixon, J.E.1    McKinnon, D.2
  • 13
    • 26844506839 scopus 로고    scopus 로고
    • The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient
    • Costantini D.L., Arruda E.P., Agarwal P., Kim K.H., Zhu Y., Zhu W., et al. The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell 123 2 (2005) 347-358
    • (2005) Cell , vol.123 , Issue.2 , pp. 347-358
    • Costantini, D.L.1    Arruda, E.P.2    Agarwal, P.3    Kim, K.H.4    Zhu, Y.5    Zhu, W.6
  • 14
    • 34447250066 scopus 로고    scopus 로고
    • Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart
    • Gaborit N., Le Bouter S., Szuts V., Varro A., Escande D., Nattel S., et al. Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J. Physiol. 582 Pt 2 (2007) 675-693
    • (2007) J. Physiol. , vol.582 , Issue.PART 2 , pp. 675-693
    • Gaborit, N.1    Le Bouter, S.2    Szuts, V.3    Varro, A.4    Escande, D.5    Nattel, S.6
  • 15
    • 0036844557 scopus 로고    scopus 로고
    • Comparison of ion-channel subunit expression in canine cardiac Purkinje fibers and ventricular muscle
    • Han W., Bao W., Wang Z., and Nattel S. Comparison of ion-channel subunit expression in canine cardiac Purkinje fibers and ventricular muscle. Circ. Res. 91 (2002) 790-797
    • (2002) Circ. Res. , vol.91 , pp. 790-797
    • Han, W.1    Bao, W.2    Wang, Z.3    Nattel, S.4
  • 16
    • 0042025143 scopus 로고    scopus 로고
    • Canine ventricular KCNE2 expression resides predominantly in Purkinje fibers
    • Pourrier M., Zicha S., Han W., and Nattel S. Canine ventricular KCNE2 expression resides predominantly in Purkinje fibers. Circ. Res. 93 (2003) 189-191
    • (2003) Circ. Res. , vol.93 , pp. 189-191
    • Pourrier, M.1    Zicha, S.2    Han, W.3    Nattel, S.4
  • 17
    • 20444376531 scopus 로고    scopus 로고
    • Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays
    • Ellinghaus P., Scheubel R.J., Dobrev D., Ravens U., Holtz J., Huetter J., et al. Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays. J. Thorac. Cardiovasc. Surg. 129 (2005) 1383-1390
    • (2005) J. Thorac. Cardiovasc. Surg. , vol.129 , pp. 1383-1390
    • Ellinghaus, P.1    Scheubel, R.J.2    Dobrev, D.3    Ravens, U.4    Holtz, J.5    Huetter, J.6
  • 19
    • 13444304421 scopus 로고    scopus 로고
    • Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart
    • Marionneau C., Couette B., Liu J., Li H., Mangoni M.E., Nargeot J., et al. Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart. J. Physiol. 562 Pt 1 (2005) 223-234
    • (2005) J. Physiol. , vol.562 , Issue.PART 1 , pp. 223-234
    • Marionneau, C.1    Couette, B.2    Liu, J.3    Li, H.4    Mangoni, M.E.5    Nargeot, J.6
  • 20
    • 64749110218 scopus 로고    scopus 로고
    • Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker
    • Chandler N.J., Greener I.D., Tellez J.O., Inada S., Musa H., Molenaar P., et al. Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation 119 12 (2009) 1562-1575
    • (2009) Circulation , vol.119 , Issue.12 , pp. 1562-1575
    • Chandler, N.J.1    Greener, I.D.2    Tellez, J.O.3    Inada, S.4    Musa, H.5    Molenaar, P.6
  • 21
    • 33750856807 scopus 로고    scopus 로고
    • Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model
    • Courtemanche M., Ramirez R.J., and Nattel S. Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model. Am. J. Physiol. 275 1 Pt 2 (1998) H301-H321
    • (1998) Am. J. Physiol. , vol.275 , Issue.1 PART 2
    • Courtemanche, M.1    Ramirez, R.J.2    Nattel, S.3
  • 22
    • 65249189288 scopus 로고    scopus 로고
    • Funny current downregulation and sinus node dysfunction associated with atrial tachyarrhythmia: a molecular basis for tachycardia-bradycardia syndrome
    • Yeh Y.H., Burstein B., Qi X.Y., Sakabe M., Chartier D., Comtois P., et al. Funny current downregulation and sinus node dysfunction associated with atrial tachyarrhythmia: a molecular basis for tachycardia-bradycardia syndrome. Circulation 119 12 (2009) 1576-1585
    • (2009) Circulation , vol.119 , Issue.12 , pp. 1576-1585
    • Yeh, Y.H.1    Burstein, B.2    Qi, X.Y.3    Sakabe, M.4    Chartier, D.5    Comtois, P.6
  • 24
    • 0023245278 scopus 로고
    • Atrioventricular nodal activation during periodic premature stimulation of the atrium
    • Billette J. Atrioventricular nodal activation during periodic premature stimulation of the atrium. Am. J. Physiol. 252 (1987) H163-H177
    • (1987) Am. J. Physiol. , vol.252
    • Billette, J.1
  • 25
    • 0030055564 scopus 로고    scopus 로고
    • Electrophysiological properties of morphologically distinct cells isolated from the rabbit atrioventricular node
    • Munk A.A., Adjemian R.A., Zhao J., Ogbaghebriel A., and Shrier A. Electrophysiological properties of morphologically distinct cells isolated from the rabbit atrioventricular node. J. Physiol. 493 (1996) 801-818
    • (1996) J. Physiol. , vol.493 , pp. 801-818
    • Munk, A.A.1    Adjemian, R.A.2    Zhao, J.3    Ogbaghebriel, A.4    Shrier, A.5
  • 26
    • 0032516476 scopus 로고    scopus 로고
    • Anatomic and functional characteristics of a slow posterior AV nodal pathway: role in dual-pathway physiology and reentry
    • Medkour D., Becker A.E., Khalife K., and Billette J. Anatomic and functional characteristics of a slow posterior AV nodal pathway: role in dual-pathway physiology and reentry. Circulation 98 (1998) 164-174
    • (1998) Circulation , vol.98 , pp. 164-174
    • Medkour, D.1    Becker, A.E.2    Khalife, K.3    Billette, J.4
  • 27
    • 23944496683 scopus 로고    scopus 로고
    • The changing epidemiology of sudden death in heart failure
    • Goldstein S. The changing epidemiology of sudden death in heart failure. Curr. Heart. Fail. Rep. 1 3 (2004) 93-97
    • (2004) Curr. Heart. Fail. Rep. , vol.1 , Issue.3 , pp. 93-97
    • Goldstein, S.1
  • 28
    • 0041413234 scopus 로고    scopus 로고
    • Hallmarks of ion channel gene expression in end-stage heart failure
    • Borlak J., and Thum T. Hallmarks of ion channel gene expression in end-stage heart failure. FASEB J. 17 12 (2003) 1592-1608
    • (2003) FASEB J. , vol.17 , Issue.12 , pp. 1592-1608
    • Borlak, J.1    Thum, T.2
  • 29
    • 51849159692 scopus 로고    scopus 로고
    • Ventricular arrhythmias after left ventricular assist device implantation
    • PubMed PMID: 18811803
    • Refaat M., Chemaly E., Lebeche D., Gwathmey J.K., and Hajjar R.J. Ventricular arrhythmias after left ventricular assist device implantation. Pacing Clin. Electrophysiol. 31 10 (2008) 1246-1252 PubMed PMID: 18811803
    • (2008) Pacing Clin. Electrophysiol. , vol.31 , Issue.10 , pp. 1246-1252
    • Refaat, M.1    Chemaly, E.2    Lebeche, D.3    Gwathmey, J.K.4    Hajjar, R.J.5
  • 30
    • 0032979720 scopus 로고    scopus 로고
    • Electrophysiological remodeling in hypertrophy and heart failure
    • Tomaselli G.F., and Marbán E. Electrophysiological remodeling in hypertrophy and heart failure. Cardiovasc. Res. 42 2 (1999) 270-283
    • (1999) Cardiovasc. Res. , vol.42 , Issue.2 , pp. 270-283
    • Tomaselli, G.F.1    Marbán, E.2
  • 31
    • 23944453689 scopus 로고    scopus 로고
    • Disease-associated changes in the expression of ion channels, ion receptors, ion exchangers and Ca(2+)-handling proteins in heart hypertrophy
    • Zwadlo C., and Borlak J. Disease-associated changes in the expression of ion channels, ion receptors, ion exchangers and Ca(2+)-handling proteins in heart hypertrophy. Toxicol. Appl. Pharmacol. 207 3 (2005) 244-256
    • (2005) Toxicol. Appl. Pharmacol. , vol.207 , Issue.3 , pp. 244-256
    • Zwadlo, C.1    Borlak, J.2
  • 32
    • 36048981858 scopus 로고    scopus 로고
    • Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function
    • Lehnart S.E., Ackerman M.J., Benson Jr. D.W., Brugada R., Clancy C.E., Donahue J.K., et al. Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation 116 20 (2007) 2325-2345
    • (2007) Circulation , vol.116 , Issue.20 , pp. 2325-2345
    • Lehnart, S.E.1    Ackerman, M.J.2    Benson Jr., D.W.3    Brugada, R.4    Clancy, C.E.5    Donahue, J.K.6
  • 33
    • 34249009224 scopus 로고    scopus 로고
    • Induction of high STAT1 expression in transgenic mice with LQTS and heart failure
    • Wu L., Archacki S.R., Zhang T., and Wang Q.K. Induction of high STAT1 expression in transgenic mice with LQTS and heart failure. Biochem. Biophys. Res. Commun. 358 2 (2007) 449-454
    • (2007) Biochem. Biophys. Res. Commun. , vol.358 , Issue.2 , pp. 449-454
    • Wu, L.1    Archacki, S.R.2    Zhang, T.3    Wang, Q.K.4
  • 34
    • 60749132806 scopus 로고    scopus 로고
    • Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases
    • Gaborit N., Wichter T., Varro A., Szuts V., Lamirault G., Eckardt L., et al. Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases. Eur. Heart J. 30 4 (2009) 487-496
    • (2009) Eur. Heart J. , vol.30 , Issue.4 , pp. 487-496
    • Gaborit, N.1    Wichter, T.2    Varro, A.3    Szuts, V.4    Lamirault, G.5    Eckardt, L.6
  • 36
    • 0037050001 scopus 로고    scopus 로고
    • New ideas about atrial fibrillation 50 years on
    • Nattel S. New ideas about atrial fibrillation 50 years on. Nature 415 (2002) 219-226
    • (2002) Nature , vol.415 , pp. 219-226
    • Nattel, S.1
  • 37
    • 23044463854 scopus 로고    scopus 로고
    • Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation
    • Gaborit N., Steenman M., Lamirault G., Le Meur N., Le Bouter S., Lande G., et al. Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation. Circulation 112 4 (2005) 471-481
    • (2005) Circulation , vol.112 , Issue.4 , pp. 471-481
    • Gaborit, N.1    Steenman, M.2    Lamirault, G.3    Le Meur, N.4    Le Bouter, S.5    Lande, G.6
  • 40
    • 55849141304 scopus 로고    scopus 로고
    • Marked differences between atrial and ventricular gene-expression remodeling in dogs with experimental heart failure
    • Cardin S., Pelletier P., Libby E., Le Bouter S., Xiao L., Kääb S., et al. Marked differences between atrial and ventricular gene-expression remodeling in dogs with experimental heart failure. J. Mol. Cell. Cardiol. 45 6 (2008) 821-831
    • (2008) J. Mol. Cell. Cardiol. , vol.45 , Issue.6 , pp. 821-831
    • Cardin, S.1    Pelletier, P.2    Libby, E.3    Le Bouter, S.4    Xiao, L.5    Kääb, S.6
  • 41
    • 21044459633 scopus 로고    scopus 로고
    • Reprogramming of the human atrial transcriptome in permanent atrial fibrillation: expression of a ventricular-like genomic signature
    • Barth A.S., Merk S., Arnoldi E., Zwermann L., Kloos P., Gebauer M., et al. Reprogramming of the human atrial transcriptome in permanent atrial fibrillation: expression of a ventricular-like genomic signature. Circ. Res. 96 9 (2005) 1022-1029
    • (2005) Circ. Res. , vol.96 , Issue.9 , pp. 1022-1029
    • Barth, A.S.1    Merk, S.2    Arnoldi, E.3    Zwermann, L.4    Kloos, P.5    Gebauer, M.6
  • 43
    • 41649102599 scopus 로고    scopus 로고
    • Differential behaviors of atrial versus ventricular fibroblasts. A potential role for platelet-derived growth factor in atrial-ventricular remodeling differences
    • Burstein B., Libby E., Calderone A., and Nattel S. Differential behaviors of atrial versus ventricular fibroblasts. A potential role for platelet-derived growth factor in atrial-ventricular remodeling differences. Circulation 117 (2008) 1630-1641
    • (2008) Circulation , vol.117 , pp. 1630-1641
    • Burstein, B.1    Libby, E.2    Calderone, A.3    Nattel, S.4
  • 44
    • 34247266577 scopus 로고    scopus 로고
    • Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development
    • Harrell M.D., Harbi S., Hoffman J.F., Zavadil J., and Coetzee W.A. Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol. Genomics 28 3 (2007) 273-283
    • (2007) Physiol. Genomics , vol.28 , Issue.3 , pp. 273-283
    • Harrell, M.D.1    Harbi, S.2    Hoffman, J.F.3    Zavadil, J.4    Coetzee, W.A.5
  • 45
    • 0035864975 scopus 로고    scopus 로고
    • Thyroid hormone and the cardiovascular system
    • Klein I., and Ojamaa K. Thyroid hormone and the cardiovascular system. N. Engl. J. Med. 344 7 (2001) 501-509
    • (2001) N. Engl. J. Med. , vol.344 , Issue.7 , pp. 501-509
    • Klein, I.1    Ojamaa, K.2
  • 46
    • 0037423665 scopus 로고    scopus 로고
    • Microarray analysis reveals complex remodeling of cardiac ion channel expression with altered thyroid status: relation to cellular and integrated electrophysiology
    • Le Bouter S., Demolombe S., Chambellan A., Bellocq C., Aimond F., Toumaniantz G., et al. Microarray analysis reveals complex remodeling of cardiac ion channel expression with altered thyroid status: relation to cellular and integrated electrophysiology. Circ. Res. 92 2 (2003) 234-242
    • (2003) Circ. Res. , vol.92 , Issue.2 , pp. 234-242
    • Le Bouter, S.1    Demolombe, S.2    Chambellan, A.3    Bellocq, C.4    Aimond, F.5    Toumaniantz, G.6
  • 47
    • 0032893049 scopus 로고    scopus 로고
    • Electrophysiologic effects of chronic amiodarone therapy and hypothyroidism, alone and in combination, on guinea pig ventricular myocytes
    • Bosch R.F., Li G.R., Gaspo R., and Nattel S. Electrophysiologic effects of chronic amiodarone therapy and hypothyroidism, alone and in combination, on guinea pig ventricular myocytes. J. Pharmacol. Exp. Ther. 289 1 (1999) 156-165
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , Issue.1 , pp. 156-165
    • Bosch, R.F.1    Li, G.R.2    Gaspo, R.3    Nattel, S.4
  • 48
    • 20844455583 scopus 로고    scopus 로고
    • Long-term amiodarone administration remodels expression of ion channel transcripts in the mouse heart
    • Le Bouter S., El Harchi A., Marionneau C., Bellocq C., Chambellan A., van Veen T., et al. Long-term amiodarone administration remodels expression of ion channel transcripts in the mouse heart. Circulation 110 19 (2004) 3028-3035
    • (2004) Circulation , vol.110 , Issue.19 , pp. 3028-3035
    • Le Bouter, S.1    El Harchi, A.2    Marionneau, C.3    Bellocq, C.4    Chambellan, A.5    van Veen, T.6
  • 49
    • 33644864000 scopus 로고    scopus 로고
    • Potassium channel subunit remodeling in rabbits exposed to long-term bradycardia or tachycardia: discrete arrhythmogenic consequences related to differential delayed-rectifier changes
    • Tsuji Y., Zicha S., Qi X.Y., Kodama I., and Nattel S. Potassium channel subunit remodeling in rabbits exposed to long-term bradycardia or tachycardia: discrete arrhythmogenic consequences related to differential delayed-rectifier changes. Circulation 113 (2006) 345-355
    • (2006) Circulation , vol.113 , pp. 345-355
    • Tsuji, Y.1    Zicha, S.2    Qi, X.Y.3    Kodama, I.4    Nattel, S.5
  • 50
    • 54449101791 scopus 로고    scopus 로고
    • Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes
    • Xiao L., Coutu P., Villeneuve L.R., Maguy A., Le Bouter S., Allen B.G., et al. Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes. Circ. Res. 103 (2008) 733-742
    • (2008) Circ. Res. , vol.103 , pp. 733-742
    • Xiao, L.1    Coutu, P.2    Villeneuve, L.R.3    Maguy, A.4    Le Bouter, S.5    Allen, B.G.6
  • 51
    • 54449090309 scopus 로고    scopus 로고
    • Cellular signalling underlying atrial tachycardia remodeling of L-type calcium-current
    • Qi X.Y., Yeh Y.H., Xiao L., Burstein B., Maguy A., Chartier D., et al. Cellular signalling underlying atrial tachycardia remodeling of L-type calcium-current. Circ. Res. 103 (2008) 845-854
    • (2008) Circ. Res. , vol.103 , pp. 845-854
    • Qi, X.Y.1    Yeh, Y.H.2    Xiao, L.3    Burstein, B.4    Maguy, A.5    Chartier, D.6
  • 52
    • 33645754478 scopus 로고    scopus 로고
    • Chronic heart rate reduction remodels ion channel transcripts in the mouse sinoatrial node but not in the ventricle
    • Leoni A.L., Marionneau C., Demolombe S., Le Bouter S., Mangoni M.E., Escande D., et al. Chronic heart rate reduction remodels ion channel transcripts in the mouse sinoatrial node but not in the ventricle. Physiol. Genomics 24 1 (2005) 4-12
    • (2005) Physiol. Genomics , vol.24 , Issue.1 , pp. 4-12
    • Leoni, A.L.1    Marionneau, C.2    Demolombe, S.3    Le Bouter, S.4    Mangoni, M.E.5    Escande, D.6
  • 53
  • 54
    • 52149123342 scopus 로고    scopus 로고
    • Feedback remodeling of cardiac potassium current expression: a novel potential mechanism for control of repolarization reserve
    • Xiao L., Xiao J., Luo X., Lin H., Wang Z., and Nattel S. Feedback remodeling of cardiac potassium current expression: a novel potential mechanism for control of repolarization reserve. Circulation 118 (2008) 983-992
    • (2008) Circulation , vol.118 , pp. 983-992
    • Xiao, L.1    Xiao, J.2    Luo, X.3    Lin, H.4    Wang, Z.5    Nattel, S.6
  • 55
    • 58149512742 scopus 로고    scopus 로고
    • Shared requirement for dynein function and intact microtubule cytoskeleton for normal surface expression of cardiac potassium channels
    • Loewen M.E., Wang Z., Eldstrom J., Dehghani Zadeh A., Khurana A., Steele D.F., et al. Shared requirement for dynein function and intact microtubule cytoskeleton for normal surface expression of cardiac potassium channels. Am. J. Physiol, Heart Circ. Physiol. 296 (2009) H71-H83
    • (2009) Am. J. Physiol, Heart Circ. Physiol. , vol.296
    • Loewen, M.E.1    Wang, Z.2    Eldstrom, J.3    Dehghani Zadeh, A.4    Khurana, A.5    Steele, D.F.6
  • 56
    • 34547101445 scopus 로고    scopus 로고
    • Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes
    • Abi-Char J., Maguy A., Coulombe A., Balse E., Ratajczak P., Samuel J.L., et al. Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes. J. Physiol. 582 Pt 3 (2007) 1205-1217
    • (2007) J. Physiol. , vol.582 , Issue.PART 3 , pp. 1205-1217
    • Abi-Char, J.1    Maguy, A.2    Coulombe, A.3    Balse, E.4    Ratajczak, P.5    Samuel, J.L.6
  • 57
    • 70349446744 scopus 로고    scopus 로고
    • The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long QT syndrome
    • X.Y. Qi, Y.H. Yeh, D. Chartier, L. Xiao, Y. Tsuji, B.J.J.M. Brundel, et al. The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long QT syndrome. Circulation Arrhythmia and Electrophysiology 2009;2:295-304.
    • (2009) Circulation Arrhythmia and Electrophysiology , vol.2 , pp. 295-304
    • Qi, X.Y.1    Yeh, Y.H.2    Chartier, D.3    Xiao, L.4    Tsuji, Y.5    Brundel, B.J.J.M.6
  • 58
    • 61749090743 scopus 로고    scopus 로고
    • Molecular and functional characterization of a new potassium conductance in mouse ventricular fibroblasts
    • Benamer N., Moha Ou Maati H., Demolombe S., Cantereau A., Delwail A., Bois P., et al. Molecular and functional characterization of a new potassium conductance in mouse ventricular fibroblasts. J. Mol. Cell. Cardiol. 46 (2009) 508-517
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 508-517
    • Benamer, N.1    Moha Ou Maati, H.2    Demolombe, S.3    Cantereau, A.4    Delwail, A.5    Bois, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.