Antisense oligodeoxynucleotides directed against Kv1.5 mRNA specifically inhibit ultrarapid delayed rectifier K+ current in cultured adult human atrial myocytes

Circulation Research

Volumn 80, Issue 4, 1997, Pages 572-579

  Feng, Jianlin ^d   Wible, Barbara ^b   Li, Gui Rong ^d   Wang, Zhiguo ^d   Nattel, Stanley ^a,c  

^a MCGILL UNIVERSITY   (Canada)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c MONTREAL HEART INSTITUTE   (Canada)

^d NONE

Author keywords

antiarrhythmic drug; cardiac action potential; heart electrophysiology; K+ channel; molecular genetics

Indexed keywords

4 AMINOPYRIDINE; ANTISENSE OLIGODEOXYNUCLEOTIDE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; POTASSIUM CHANNEL;

ADULT; AGED; ARTICLE; BASE MISPAIRING; CLINICAL ARTICLE; CONTROLLED STUDY; GENE MUTATION; HEART ATRIUM MUSCLE; HEART VENTRICLE WALL; HUMAN; HUMAN CELL; POTASSIUM CURRENT; PRIORITY JOURNAL;

EID: 0031003283     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.80.4.572     Document Type: Article

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