Deficiency of ferritin heavy-chain nuclear import in triple A syndrome implies nuclear oxidative damage as the primary disease mechanism

Molecular Endocrinology

Volumn 23, Issue 12, 2009, Pages 2086-2094

  Storr, Helen L ^a   Kind, Barbara ^b   Parfitt, David A ^a   Chapple, J Paul ^a   Lorenz, M ^c   Koehler, Katrin ^b   Huebner, Angela ^b   Clark, Adrian J L ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; COMPLEMENTARY DNA; FERRITIN; FERRITIN HEAVY CHAIN PROTEIN; HYDROGEN PEROXIDE; PROTEIN ALADIN; UNCLASSIFIED DRUG;

AAAS GENE; ALLGROVE SYNDROME; APOPTOSIS; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FIBROBLAST; FLUORESCENCE MICROSCOPY; FTH1 GENE; GENE; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ACTIVE TRANSPORT, CELL NUCLEUS; ADRENAL INSUFFICIENCY; APOFERRITINS; CELL LINE; CELLS, CULTURED; ESOPHAGEAL ACHALASIA; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC VECTORS; HUMANS; MICROSCOPY, CONFOCAL; NERVE TISSUE PROTEINS; NUCLEAR PORE COMPLEX PROTEINS; PROTEIN BINDING; TWO-HYBRID SYSTEM TECHNIQUES;

BACTERIA (MICROORGANISMS);

EID: 73249122503     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2009-0056     Document Type: Article

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