Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Nature

Volumn 376, Issue 6535, 1995, Pages 37-43

  Nicholson, Donald W ^a   Ali, Ambereen ^a   Thornberry, Nancy A ^b   Vaillancourt, John P ^a   Ding, Connie K ^b   Gallant, Michel ^a   Gareau, Yves ^a   Griffin, Patrick R ^b   Labelle, Marc ^a   Lazebnik, Yuri A ^c   Munday, Neil A ^a   Raju, Sayyaparaju M ^b   Smulson, Mark E ^d   Yamin, Ting Ting ^b   Yu, Violeta L ^a   Miller, Douglas K ^b  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

^c Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^d GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEINASE;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL DEATH; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMAL; APOPTOSIS; CAENORHABDITIS ELEGANS; CASPASE 1; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENZYME PRECURSORS; HELMINTH PROTEINS; HUMAN; KINETICS; MOLECULAR SEQUENCE DATA; POLY(ADP-RIBOSE) POLYMERASES; SPECTRUM ANALYSIS, MASS; TUMOR CELLS, CULTURED;

EID: 0029068871     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/376037a0     Document Type: Article

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