메뉴 건너뛰기




Volumn 13, Issue 5, 2009, Pages 221-226

The role of TCR-ζ expression in immunosuppression induced by tumour;Znaczenie ekspresji TCR-ζ w immunosupresji indukowanej przez nowotwór

Author keywords

chain expression; Cancers; T lymphocytes

Indexed keywords

CD16 ANTIGEN; CD3 ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG;

EID: 73249117842     PISSN: 14282526     EISSN: 14282526     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (1)

References (48)
  • 3
    • 0028186833 scopus 로고
    • Tumor-infiltrating lymphocytes in human solid tumors
    • Whiteside TL. Tumor-infiltrating lymphocytes in human solid tumors. Immunol Ser 1994; 61: 137-48.
    • (1994) Immunol Ser , vol.61 , pp. 137-148
    • Whiteside, T.L.1
  • 4
    • 0028365168 scopus 로고
    • Tumor-infiltrating lymphocytes: Their phenotype, function and clinical use
    • Whiteside TL, Parmiani G. Tumor-infiltrating lymphocytes: their phenotype, function and clinical use. Cancer Immunol Immunother 1994; 39: 15-21.
    • (1994) Cancer Immunol Immunother , vol.39 , pp. 15-21
    • Whiteside, T.L.1    Parmiani, G.2
  • 5
    • 0034048905 scopus 로고    scopus 로고
    • Spontaneous apoptosis of CD8+ T lymphocytes in peripheral blood of patients with advanced melanoma
    • Saito T, Dworacki G, Gooding W, Lotze MT, Whiteside TL. Spontaneous apoptosis of CD8+ T lymphocytes in peripheral blood of patients with advanced melanoma. Clin Cancer Res 2000; 6: 1351-64.
    • (2000) Clin Cancer Res , vol.6 , pp. 1351-1364
    • Saito, T.1    Dworacki, G.2    Gooding, W.3    Lotze, M.T.4    Whiteside, T.L.5
  • 6
    • 0031747564 scopus 로고    scopus 로고
    • The role of Fas/FasL in immunosuppression induced by human tumors
    • Whiteside TL, Rabinowich H. The role of Fas/FasL in immunosuppression induced by human tumors. Cancer Immunol Immunother 1998; 46: 175-84.
    • (1998) Cancer Immunol Immunother , vol.46 , pp. 175-184
    • Whiteside, T.L.1    Rabinowich, H.2
  • 8
    • 0036155925 scopus 로고    scopus 로고
    • Tumor-induced death of immune cells: Its mechanisms and consequences
    • Whiteside TL. Tumor-induced death of immune cells: its mechanisms and consequences. Semin Cancer Biol 2002; 12: 43-50.
    • (2002) Semin Cancer Biol , vol.12 , pp. 43-50
    • Whiteside, T.L.1
  • 9
    • 0032698214 scopus 로고    scopus 로고
    • Fas ligand is expressed on human squamous cell carcinomas of the head and neck and it promotes apoptosis of T lymphocytes
    • Gastman BR, Atarashi Y, Reichert TE, Saito T, Balkir L, Rabinowich H, Whiteside TL. Fas ligand is expressed on human squamous cell carcinomas of the head and neck and it promotes apoptosis of T lymphocytes. Cancer Res 1999; 59: 5356-64.
    • (1999) Cancer Res , vol.59 , pp. 5356-5364
    • Gastman, B.R.1    Atarashi, Y.2    Reichert, T.E.3    Saito, T.4    Balkir, L.5    Rabinowich, H.6    Whiteside, T.L.7
  • 10
    • 0036795213 scopus 로고    scopus 로고
    • Signaling abnormalities and reduced proliferation of circulating and tumor-infiltrating lymphocytes in patients with oral carcinoma
    • Reichert TE, Strauss L, Wagner EM, Gooding W, Whiteside TL. Signaling abnormalities and reduced proliferation of circulating and tumor-infiltrating lymphocytes in patients with oral carcinoma. Clin Cancer Res 2002; 8: 3137-45.
    • (2002) Clin Cancer Res , vol.8 , pp. 3137-3145
    • Reichert, T.E.1    Strauss, L.2    Wagner, E.M.3    Gooding, W.4    Whiteside, T.L.5
  • 11
    • 0029808372 scopus 로고    scopus 로고
    • The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
    • O'Connell J, O'Sullivan GD, Collins JK, Shanahan F. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand. J Exp Med 1996; 184: 1075-82.
    • (1996) J Exp Med , vol.184 , pp. 1075-1082
    • O'Connell, J.1    O'Sullivan, G.D.2    Collins, J.K.3    Shanahan, F.4
  • 13
    • 4444339448 scopus 로고    scopus 로고
    • The role of monocytes/macrophages in TCR-zeta chain downregulation and apoptosis in malignant pleural effusions
    • Sikora J, Dworacki G, Giersz R, Zeromski J. The role of monocytes/macrophages in TCR-zeta chain downregulation and apoptosis in malignant pleural effusions. J Biol Regul Homeost Agents 2004; 18: 26-32.
    • (2004) J Biol Regul Homeost Agents , vol.18 , pp. 26-32
    • Sikora, J.1    Dworacki, G.2    Giersz, R.3    Zeromski, J.4
  • 14
    • 0030035046 scopus 로고    scopus 로고
    • Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma
    • Lai P, Rabinowich H, Crowley-Nowick PA, Bell MC, Mantovani G, Whiteside TL. Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma. Clin Cancer Res 1996; 2: 161-73.
    • (1996) Clin Cancer Res , vol.2 , pp. 161-173
    • Lai, P.1    Rabinowich, H.2    Crowley-Nowick, P.A.3    Bell, M.C.4    Mantovani, G.5    Whiteside, T.L.6
  • 15
    • 0027378767 scopus 로고
    • Loss of T-cell receptor chain and p56lck in T-cells infiltrating human renal cell carcinoma
    • Finke JH, Zea AH, Stanley J, et al. Loss of T-cell receptor chain and p56lck in T-cells infiltrating human renal cell carcinoma. Cancer Res 1993; 53: 5613-6.
    • (1993) Cancer Res , vol.53 , pp. 5613-5616
    • Finke, J.H.1    Zea, A.H.2    Stanley, J.3
  • 16
    • 0032102948 scopus 로고    scopus 로고
    • Impaired expression and function of signal-transducing zeta chains in peripheral T cells and natural killer cells in patients with prostate cancer
    • Healy CG, Simons JW, Carducci MA, DeWeese TL, Bartkowski M, Tong KP, Bolton WE. Impaired expression and function of signal-transducing zeta chains in peripheral T cells and natural killer cells in patients with prostate cancer. Cytometry 1998; 32: 109-19.
    • (1998) Cytometry , vol.32 , pp. 109-119
    • Healy, C.G.1    Simons, J.W.2    Carducci, M.A.3    DeWeese, T.L.4    Bartkowski, M.5    Tong, K.P.6    Bolton, W.E.7
  • 17
    • 0028829736 scopus 로고
    • Alterations in T cell receptor and signal transduction molecules in melanoma patients
    • Zea AH, Curti DB, Longo DL, et al. Alterations in T cell receptor and signal transduction molecules in melanoma patients. Clin Cancer Res 1995; 1: 1327-35.
    • (1995) Clin Cancer Res , vol.1 , pp. 1327-1335
    • Zea, A.H.1    Curti, D.B.2    Longo, D.L.3
  • 18
    • 0032972946 scopus 로고    scopus 로고
    • Clinical significance of decreased zeta chain expression in peripheral blood lymphocytes of patients with head and neck cancer
    • Kuss I, Saito T, Johnson JT, Whiteside TL. Clinical significance of decreased zeta chain expression in peripheral blood lymphocytes of patients with head and neck cancer. Clin Cancer Res 1999; 5: 329-34.
    • (1999) Clin Cancer Res , vol.5 , pp. 329-334
    • Kuss, I.1    Saito, T.2    Johnson, J.T.3    Whiteside, T.L.4
  • 19
    • 0032824973 scopus 로고    scopus 로고
    • Signaling defects in T lymphocytes of patients with malignancy
    • Whiteside TL. Signaling defects in T lymphocytes of patients with malignancy. Cancer Immunol Immunother 1999; 48: 346-52.
    • (1999) Cancer Immunol Immunother , vol.48 , pp. 346-352
    • Whiteside, T.L.1
  • 22
    • 0032563231 scopus 로고    scopus 로고
    • Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation
    • Kersh EN, Shaw AS, Allen PM. Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation. Science 1998; 281: 572-5.
    • (1998) Science , vol.281 , pp. 572-575
    • Kersh, E.N.1    Shaw, A.S.2    Allen, P.M.3
  • 23
    • 10144250282 scopus 로고    scopus 로고
    • HIV infection-induced posttranslational modification of T cell signaling molecules associated with disease progression
    • Stefanová I, Saville MW, Peters C, et al. HIV infection-induced posttranslational modification of T cell signaling molecules associated with disease progression. J Clin Invest 1996; 98: 1290-7.
    • (1996) J Clin Invest , vol.98 , pp. 1290-1297
    • Stefanová, I.1    Saville, M.W.2    Peters, C.3
  • 24
    • 0031906460 scopus 로고    scopus 로고
    • Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy
    • Zea AH, Ochoa MT, Ghosh P, et al. Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy. Infect Immun 1998; 66: 499.
    • (1998) Infect Immun , vol.66 , pp. 499
    • Zea, A.H.1    Ochoa, M.T.2    Ghosh, P.3
  • 25
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TCR/CD3-mediated protein-tyrosylphosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain
    • Liossis SN, Ding XZ, Dennis GJ, Tsokos GC. Altered pattern of TCR/CD3-mediated protein-tyrosylphosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain. J Clin Invest 1998; 101: 1448-57.
    • (1998) J Clin Invest , vol.101 , pp. 1448-1457
    • Liossis, S.N.1    Ding, X.Z.2    Dennis, G.J.3    Tsokos, G.C.4
  • 26
    • 0034053833 scopus 로고    scopus 로고
    • The T-cell receptor zeta contains two homologous domains with which similar immunodeficiency virus Nef interacts and mediates down-modulation
    • Schaeffer TM, Bell I, Fallert BA, Reinhart TA.The T-cell receptor zeta contains two homologous domains with which similar immunodeficiency virus Nef interacts and mediates down-modulation. J Virol 2000; 74: 3273-83.
    • (2000) J Virol , vol.74 , pp. 3273-3283
    • Schaeffer, T.M.1    Bell, I.2    Fallert, B.A.3    Reinhart, T.A.4
  • 27
    • 1842331510 scopus 로고    scopus 로고
    • Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation
    • Valitutti S, Muller S, Salio M, Lanzavecchia A. Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation. J Exp Med 1997; 185: 1859-64.
    • (1997) J Exp Med , vol.185 , pp. 1859-1864
    • Valitutti, S.1    Muller, S.2    Salio, M.3    Lanzavecchia, A.4
  • 29
    • 0027453988 scopus 로고
    • Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma
    • Nakagomi H, Petersson M, Magnusson I, et al. Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res 1993; 53: 5610-2.
    • (1993) Cancer Res , vol.53 , pp. 5610-5612
    • Nakagomi, H.1    Petersson, M.2    Magnusson, I.3
  • 30
    • 0029042847 scopus 로고
    • Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: Correlation with the stage of the disease
    • Matsuda M, Petersson M, Lenke R, Taupin JL, Magnusson I, Mellstedt H, Anderson P, Kiessling R. Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease. Int J Cancer 1995; 61: 765-72.
    • (1995) Int J Cancer , vol.61 , pp. 765-772
    • Matsuda, M.1    Petersson, M.2    Lenke, R.3    Taupin, J.L.4    Magnusson, I.5    Mellstedt, H.6    Anderson, P.7    Kiessling, R.8
  • 31
    • 0031846804 scopus 로고    scopus 로고
    • Immune cells in the tumor microenvironment: Mechanisms responsible for signaling and functional defects
    • Reichert TE, Rabinowich H, Johnson JT, Whiteside TL. Immune cells in the tumor microenvironment: mechanisms responsible for signaling and functional defects. J Immunother 1998; 21: 295-306.
    • (1998) J Immunother , vol.21 , pp. 295-306
    • Reichert, T.E.1    Rabinowich, H.2    Johnson, J.T.3    Whiteside, T.L.4
  • 32
    • 0035875380 scopus 로고    scopus 로고
    • Modulation of TcR/CD3-zeta chain expression by a circulating factor derived from ovarian cancer patients
    • Taylor DD, Bender DP, Gerçel-Taylor C, Stanson J, Whiteside TL. Modulation of TcR/CD3-zeta chain expression by a circulating factor derived from ovarian cancer patients. Br J Cancer 2001; 84: 1624-9.
    • (2001) Br J Cancer , vol.84 , pp. 1624-1629
    • Taylor, D.D.1    Bender, D.P.2    Gerçel-Taylor, C.3    Stanson, J.4    Whiteside, T.L.5
  • 33
    • 0035138089 scopus 로고    scopus 로고
    • Gangliosides mediate neuroblastoma-induced inhibition of dendritic cell generation
    • Shurin GV, Shurin MR, Lotze MT, Barksdale EM. Gangliosides mediate neuroblastoma-induced inhibition of dendritic cell generation. Cancer Res 2001; 61: 363-9.
    • (2001) Cancer Res , vol.61 , pp. 363-369
    • Shurin, G.V.1    Shurin, M.R.2    Lotze, M.T.3    Barksdale, E.M.4
  • 36
    • 0030048536 scopus 로고    scopus 로고
    • Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell and natural killer cell-mediated cytoxicity
    • Kono K, Salazar-Onfray F, Petersson M, et al. Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell and natural killer cell-mediated cytoxicity. Eur J Immunol 1996; 26: 1308.
    • (1996) Eur J Immunol , vol.26 , pp. 1308
    • Kono, K.1    Salazar-Onfray, F.2    Petersson, M.3
  • 37
    • 0034642401 scopus 로고    scopus 로고
    • A modified JAM assay detects apoptosis induced in activated lymphocytes by FasL+ human adherent tumor cells
    • Atarashi Y, Kanaya H, Whiteside TL. A modified JAM assay detects apoptosis induced in activated lymphocytes by FasL+ human adherent tumor cells. J Immunol Methods 2000; 233: 179-83.
    • (2000) J Immunol Methods , vol.233 , pp. 179-183
    • Atarashi, Y.1    Kanaya, H.2    Whiteside, T.L.3
  • 39
    • 0037137567 scopus 로고    scopus 로고
    • Apoptosis of immune cells in the tumor microenvironment and peripheral circulation of patients with cancer: Implications for immunotherapy
    • Whiteside TL. Apoptosis of immune cells in the tumor microenvironment and peripheral circulation of patients with cancer: implications for immunotherapy. Vaccine 2002; 20 (suppl 4): A46-51.
    • (2002) Vaccine , vol.20 , Issue.SUPPL. 4
    • Whiteside, T.L.1
  • 40
    • 0032403180 scopus 로고    scopus 로고
    • Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma
    • Reichert TE, Day R, Wagner EM, Whiteside TL. Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma. Cancer Res 1998; 58: 5344-7.
    • (1998) Cancer Res , vol.58 , pp. 5344-5347
    • Reichert, T.E.1    Day, R.2    Wagner, E.M.3    Whiteside, T.L.4
  • 41
    • 0036023415 scopus 로고    scopus 로고
    • Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance
    • Hoffmann TK, Dworacki G, Meidenbauer N, Gooding W, Johnson JT, Whiteside TL. Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance. Clin Cancer Res 2002; 8: 2553-62.
    • (2002) Clin Cancer Res , vol.8 , pp. 2553-2562
    • Hoffmann, T.K.1    Dworacki, G.2    Meidenbauer, N.3    Gooding, W.4    Johnson, J.T.5    Whiteside, T.L.6
  • 42
    • 0032550366 scopus 로고    scopus 로고
    • Conversion of membrane-bound Fas (CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
    • Schneider P, Holler N, Bodmer J, Hahne M, Frei K, Fontana A, Tschopp J. Conversion of membrane-bound Fas (CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med 1998; 187: 1205-13.
    • (1998) J Exp Med , vol.187 , pp. 1205-1213
    • Schneider, P.1    Holler, N.2    Bodmer, J.3    Hahne, M.4    Frei, K.5    Fontana, A.6    Tschopp, J.7
  • 43
    • 4744356643 scopus 로고    scopus 로고
    • FasL-containing microvesicles in the circulation of patients with cancer induce apoptosis of activated T lymphocytes
    • Kim JW, Wieckowski E, Taylor DD, Reichert TE, Whiteside TL. FasL-containing microvesicles in the circulation of patients with cancer induce apoptosis of activated T lymphocytes. J Immunother 2003; 26: 44.
    • (2003) J Immunother , vol.26 , pp. 44
    • Kim, J.W.1    Wieckowski, E.2    Taylor, D.D.3    Reichert, T.E.4    Whiteside, T.L.5
  • 44
    • 0035370880 scopus 로고    scopus 로고
    • The number of intratumoral dendritic cells and zeta-chain expression in T cells as prognostic and survival biomarkers in patients with oral carcinoma
    • Reichert TE, Scheuer C, Day R, Wagner W, Whiteside TL. The number of intratumoral dendritic cells and zeta-chain expression in T cells as prognostic and survival biomarkers in patients with oral carcinoma. Cancer 2001; 91: 2136-47.
    • (2001) Cancer , vol.91 , pp. 2136-2147
    • Reichert, T.E.1    Scheuer, C.2    Day, R.3    Wagner, W.4    Whiteside, T.L.5
  • 45
    • 0028829736 scopus 로고
    • Alterations in T cell receptor and signal transduction molecules in melanoma patients
    • Zea AH, Curti BD, Longo DL, et al. Alterations in T cell receptor and signal transduction molecules in melanoma patients. Clin Cancer Res 1995; 11: 1327-35.
    • (1995) Clin Cancer Res , vol.11 , pp. 1327-1335
    • Zea, A.H.1    Curti, B.D.2    Longo, D.L.3
  • 46
    • 12244261579 scopus 로고    scopus 로고
    • Expression of zeta in T cells prior to IL-2 therapy as a predictor of response and survival in patients with ovarian carcinoma
    • Kuss I, Rabinowich H, Gooding W, Edwards R, Whiteside TL. Expression of zeta in T cells prior to IL-2 therapy as a predictor of response and survival in patients with ovarian carcinoma. Cancer Biother Radiopharm 2002; 17: 631-40.
    • (2002) Cancer Biother Radiopharm , vol.17 , pp. 631-640
    • Kuss, I.1    Rabinowich, H.2    Gooding, W.3    Edwards, R.4    Whiteside, T.L.5
  • 47
    • 0029737843 scopus 로고    scopus 로고
    • Expression and activity of signaling molecules in T lymphocytes obtained from patients with metastatic melanoma before and after interleukin 2 therapy
    • Rabinowich H, Banks M, Reichert TE, Logan TF, Kirkwood JM, Whiteside TL. Expression and activity of signaling molecules in T lymphocytes obtained from patients with metastatic melanoma before and after interleukin 2 therapy. Clin Cancer Res 1996; 2: 1263-74.
    • (1996) Clin Cancer Res , vol.2 , pp. 1263-1274
    • Rabinowich, H.1    Banks, M.2    Reichert, T.E.3    Logan, T.F.4    Kirkwood, J.M.5    Whiteside, T.L.6
  • 48
    • 0028568628 scopus 로고
    • The decreased expression of CD3 zeta chains in cancer patients is not reversed by IL-2 administration
    • Farace F, Angevin E, Vanderplancke J, Escudier B, Triebel F. The decreased expression of CD3 zeta chains in cancer patients is not reversed by IL-2 administration. Int J Cancer 1994; 59: 752-5.
    • (1994) Int J Cancer , vol.59 , pp. 752-755
    • Farace, F.1    Angevin, E.2    Vanderplancke, J.3    Escudier, B.4    Triebel, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.