Tumor's other immune targets: Dendritic cells

Journal of Leukocyte Biology

Volumn 66, Issue 2, 1999, Pages 336-344

  Esche, Clemens ^b   Lokshin, Anna ^b   Shurin, Galina V ^b   Gastman, Brian R ^b   Rabinowich, Hannah ^b   Watkins, Simon C ^b   Lotze, Michael T ^b   Shurin, Michael R ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b NONE

Author keywords

Apoptosis; Bcl 2; Immunosuppression

Indexed keywords

CASPASE 3; DNA FRAGMENT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRUCTURE; DENDRITIC CELL; DNA CLEAVAGE; DNA DETERMINATION; ENZYME ACTIVITY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; TUMOR ESCAPE;

ANIMALIA; MURINAE;

EID: 0008055549     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.66.2.336     Document Type: Article

References (63)

1. Restifo, N. P., Esquivel, F., Kawakami, Y., Yewdell, J. W., Mule, J. J., Rosenberg, S. A., Bennink, J. R. (1993) Identification of human cancers deficient in antigen processing. J. Exp. Med. 177, 265-272.
2. Chen, L., Ashe, S., Brady, W. A., Hellstrom, I., Hellstrom, K. E., Ledbetter, J. A., McGowan, P., Linsley, P. S. (1992) Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 71, 1093-1102.
3. Wojtowicz-Praga, S. (1997) Reversal of tumor-induced immunosuppression: a new approach to cancer therapy [see comments]. J. Immunother. 20, 165-177.
4. Gastl, G. A., Abrams, J. S., Nanus, D. M., Oosterkamp, R., Silver, J., Liu, F., Chen, M., Albino, A. P., Bander, N. H. (1993) Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression. Int. J. Cancer 55, 96-101.
5. Gabrilovich, D. I., Chen, H. L., Girgis, K. R., Cunningham, H. T., Meny, G. M., Nadaf, S., Kavanaugh, D., Carbone, D. P. (1996) Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nature Med. 2, 1096-1103 [published erratum appears in Nature Med. (1996) 2 (11), 1267].
6. Kavanaugh, D. Y., Carbone, D. P. (1996) Immunologic dysfunction in cancer. Hematol. Oncol. Clin. North Am. 10, 927-951.
7. O'Mahony, A. M., O'Sullivan, G. C., O'Connell, J., Cotter, T. G., Collins, J. K. (1993) An immune suppressive factor derived from esophageal squamous carcinoma induces apoptosis in normal and transformed cells of lymphoid lineage. J. Immunol. 151, 4847-4856.
8. Shurin, M. R., Esche, C., Lokshin, A., Lotze, M. T. (1999) Apoptosis in dendritic cells. In Dendritic Cells: Biology and Clinical Applications (M. T. Lotze, A. W. Thomson, eds.) San Diego, CA: Academic Press, 673-692.
9. Vujanovic, N. L., Basse, P., Herberman, R. B., Whiteside, T. L. (1996) Antitumor functions of natural killer cells and control of metastases. Methods 9, 394-408.
10. Darzynkiewicz, Z., Juan, G., Li, X., Gorczyca, W., Murakami, T., Traganos, F. (1997) Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry 27, 1-20.
11. Arends, M. J., Morris, R. G., Wyllie, A. H. (1990) Apoptosis. The role of the endonuclease. Am. J. Pathol. 136, 593-608.
12. Cohen, G. M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16.
13. Nagata, S. (1997) Apoptosis by death factor. Cell 88, 355-365.
14. Fesus, L., Madi, A., Balajthy, Z., Nemes, Z., Szondy, Z. (1996) Transglutaminase induction by various cell death and apoptosis pathways. Experientia 52, 942-949.
15. Walker, P. R., Saas, P., Dietrich, P. Y. (1997) Role of Fas ligand (CD95L) in immune escape: the tumor cell strikes back. J. Immunol. 158, 4521-4524.
16. Brown, D. G., Sun, X. M., Cohen, G. M. (1993) Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268, 3037-3039.
17. Fesus, L. (1993) Biochemical events in naturally occurring forms of cell death. FEBS Lett. 328, 1-5.
18. Shurin, M. R., Pandharipande, P. P., Zorina, T. D., Haluszczak, C., Subbotin, V. M., Hunter, O., Brumfield, A., Storkus, W. J., Maraskovsky, E., Lotze, M. T. (1997) FLT3 ligand induces the generation of functionally active dendritic cells in mice. Cell. Immunol. 179, 174-184.
19. Matzinger, P. (1991) The JAM test. A simple assay for DNA fragmentation and cell death. J. Immunol. Meth. 145, 185-192.
20. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
21. Lokshin, A., Mayotte, J. E., Levitt, M. L. (1995) Mechanism of interferon beta-induced squamous differentiation and programmed cell death in human non-small-cell lung cancer cell lines. J. Natl. Cancer Inst. 87, 206-212.
22. Lokshin, A., Levitt, M. L. (1996) Effect of suramin on squamous differentiation and apoptosis in three human non-small-cell lung cancer cell lines. J. Cell. Biochem. (Suppl.) 24, 186-197.
23. Yamabe, K., Peron, J. M., Esche, C., Lotze, M. T., Shurin, M. R. (1998) New method for the isolation of murine lymphoid dendritic cells: Kinetics of short-time survival in culture. J. Leukoc. Biol. (Suppl. 2) 64, 17a.
24. Fernandes-Alnemri, T., Litwack, G., Alnemri, E. S. (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem. 269, 30761-30764.
25. Brown, R. (1997) The bcl-2 family of proteins. Br. Med. Bull. 53, 466-477.
26. Chouaib, S., Asselin-Paturel, C., Mami-Chouaib, F., Caignard, A., Blay, J. Y. (1997) The host-tumor immune conflict: from immunosuppression to resistance and destruction. Immunol. Today 18, 493-497.
27. Shurin, M. R. (1996) Dendritic cells presenting tumor antigen. Cancer. Immunol. Immunother. 43, 158-164.
28. Esche, C., Shurin, M. R., Lotze, M. T. (1999) The use of dendritic cells for cancer vaccination. Curr. Op. Mol. Ther. 1, 72-81.
29. Garcia-Plata, D., Lessana-Leibowitch, M., Palangie, A., Gulliemette, J., Sedel, D., Mendez, L., Mozos, E. (1995) Immunophenotype analysis of dendritic cells and lymphocytes associated with cutaneous malignant melanomas. Invasion Metastasis 15, 125-134.
30. Enk, A. H., Jonuleit, H., Saloga, J., Knop, J. (1997) Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma. Int. J. Cancer 73, 309-316.
31. Gabrilovich, D. I., Corak, J., Ciernik, I. F., Kavanaugh, D., Carbone, D. P. (1997) Decreased antigen presentation by dendritic cells in patients with breast cancer. Clin. Cancer Res. 3, 483-490.
32. Nestle, F. O., Burg, G., Fah, J., Wrone-Smith, T., Nickoloff, B. J. (1997) Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells. Am. J. Pathol. 150, 641-651.
33. + dendritic cells. Immunol. 86, 15a.
34. + T cells. J. Exp. Med. 186, 801-812.
35. Fugier-Vivier, I., Servet-Delprat, C., Rivailler, P., Rissoan, M. C., Liu, Y. J., Rabourdin-Combe, C. (1997) Measles virus suppresses cell-mediated immunity by interfering with the survival and functions of dendritic and T cells. J. Exp. Med. 186, 813-823.
36. Fu, E. J., Area, M. J., Hain, J. M., Krinock, R., Rado, J., Cameron, M. J., Chang, A. E., Sondak, V. K. (1997) Tumor-induced suppression of antitumor reactivity and depression of TCRzeta expression in tumor-draining lymph node lymphocytes: possible relationship to the Th2 pathway. J. Immunother. 20, 111-122.
37. Ghosh, P., Komschlies, K. L., Cippitelli, M., Longo, D. L., Subleski, J., Ye, J., Sica, A., Young, H. A., Wiltrout, R. H., Ochoa, A. C. (1995) Gradual loss of T-helper 1 populations in spleen of mice during progressive tumor growth. J. Natl. Cancer Inst. 87, 1478-1483.
38. Handel-Fernandez, M. E., Cheng, X., Herbert, L. M., Lopez, D. M. (1997) Down-regulation of IL-12, not a shift from a T helper-1 to a T helper-2 phenotype, is responsible for impaired IFN-gamma production in mammary tumor-bearing mice. J. Immunol. 158, 280-286.
39. Asselin-Paturel, C., Echchakir, H., Carayol, G., Gay, F., Opolon, P., Grunenwald, D., Chouaib, S., Mami-Chouaib, F. (1998) Quantitative analysis of Th1, Th2 and TGF-betal cytokine expression in tumor, TIL and PBL of non-small cell lung cancer patients. Int. J. Cancer 77, 7-12.
40. Kobayashi, M., Kobayashi, H., Pollard, R. B., Suzuki, F. (1998) A pathogenic role of Th2 cells and their cytokine products on the pulmonary metastasis of murine B16 melanoma. J. Immunol. 160, 5869-5873.
41. Shurin, M. R., Esche, C., Peron, J. M., Lotze, M. T. (1997) Antitumor activities of IL-12 and mechanisms of action. Chem. Immunol. 68, 153-174.
42. Kitajima, T., Ariizumi, K., Bergstresser, P. R., Takashima, A. (1996) Ultraviolet B radiation sensitizes a murine epidermal dendritic cell line (XS52) to undergo apoptosis upon antigen presentation to T cells. J. Immunol. 157, 3312-3316.
43. O'Connell, J., O'Sullivan, G. C., Collins, J. K., Shanahan, F. (1996) The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand. J. Exp. Med. 184, 1075-1082.
44. von Stebut, E., Philipp, S., Wurz, C., Ringling, M., Kolde, G. (1997) Apoptosis of cultured Langerhans cells is mediated by the CD95 (APO-1/ Fas)/CD95L-system. J. Invest. Dermatol. 109, 406a.
45. Lu, L., Qian, S., Hershberger, P. A., Rudert, W. A., Lynch, D. H., Thomson, A. W. (1997) Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation. J. Immunol. 158, 5676-5684.
46. Shortman, K., Wu, L., Ardavin, C., Vremec, D., Stozik, F., Winkel, K., Suss, G. (1995) Thymic dendritic cells: surface phenotype, developmental origin and function. Adv. Exp. Med. Biol. 378, 21-29.
47. Süss, G., Shortman, K. (1996) A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis. J. Exp. Med. 183, 1789-1796.
48. Bonham, C. A., Lu, L., Hoffman, R. A., Simmons, R. L., Thomson, A. W. (1997) Nitric oxide production by dendritic cells is associated with impairment of T cell responses. Transplant. Proc. 29, 1116-1117.
49. Ludewig, B., Graf, D., Gelderblom, H. R., Becker, Y., Kroczek, R. A., Pauli, G. (1995) Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40-ligand) and TNF-alpha, but strongly enhanced by interleukin-10. Eur. J. Immunol. 25, 1943-1950.
50. Esche, C., Gambotto, A., Satoh, Y., Gerein, V., Robbins, P. D., Watkins, S. C., Lotze, M. T., Shurin, M. R. (1999) CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth. Eur. J. Immunol. 29, 2148-2155.
51. Guzman, C. A., Domann, E., Rohde, M., Bruder, D., Darji, A., Weiss, S., Wehland, J., Chakraborty, T., Timmis, K. N. (1996) Apoptosis of mouse dendritic cells is triggered by listeriolysin, the major virulence determinant of Listeria monocytogenes. Mol. Microbiol. 20, 119-126.
52. Albert, M. L., Sauter, B., Bhardwaj, N. (1998) Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392, 86-89.
53. Fraser, A., Evan, G. (1996) A license to kill. Cell 85, 781-784.
54. Henkart, P. A. (1996) ICE family proteases: mediators of all apoptotic cell death? Immunity 4, 195-201.
55. Lotze, M. T. (1997) Getting to the source: dendritic cells as therapeutic reagents for the treatment of patients with cancer [editorial; comment]. Ann. Surg. 226, 1-5.
56. Stene, M. A., Babajanians, M., Bhuta, S., Cochran, A. J. (1988) Quantitative alterations in cutaneous Langerhans cells during the evolution of malignant melanoma of the skin. J. Invest. Dermatol. 91, 125-128.
57. Toriyama, K., Wen, D. R., Paul, E., Cochran, A. J. (1993) Variations in the distribution, frequency, and phenotype of Langerhans cells during the evolution of malignant melanoma of the skin. J. Invest. Dermatol. 100, 269S-273S.
58. Shurin, M. R., Esche, C., Lotze, M. T. (1998) FLT3: receptor and ligand. Biology and potential clinical application. Cytokine Growth Factor Rev. 9, 37-48.
59. Maraskovsky, E., Brasel, K., Teepe, M., Roux, E. R., Lyman, S. D., Shortman, K., McKenna, H. J. (1996) Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J. Exp. Med. 184, 1953-1962.
60. Esche, C., Subbotin, V. M., Hunter, O., Lotze, M. T., Shurin, M. R. (1998) Flt3 ligand and interleukin-12 regulate accumulation of dendritic cells and mast cells in murine skin. Arch Dermatol. Res. 290, 87a (abstr).
61. Shurin, M. R., Maraskovsky, E., Lotze, M. T. (1996) FLT3 ligand inhibits tumor progression in murine mcdel. J. Immunother. 19, 466a.
62. Esche, C., Subbotin, V. M., Maliszewski, C., Lotze, M. T., Shurin, M. R. (1998) FLT3 ligand administration inhibits tumor growth in murine melanoma and lymphoma. Canter Res. 58, 380-383.
63. Peron, J. M., Esche, C., Subbotin, V. M., Maliszewski, C., Lotze, M. T., Shurin, M. R. (1998) FLT3-ligand administration inhibits liver metastases: role of NK cells. J. Immunol. 161, 6164-6170.