Expression of leptin and long-form leptin-receptor proteins in porcine hypothalamus during oestrous cycle and pregnancy

Reproduction in Domestic Animals

Volumn 44, Issue 6, 2009, Pages 920-926

  Siawrys, G ^a   Kaminski, T ^a   Smolinska, N ^a   Przala, J ^a  

^a UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR;

ANIMAL; ARTICLE; BREEDING; CLASSIFICATION; ESTRUS CYCLE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HYPOTHALAMUS; METABOLISM; PHYSIOLOGY; PREGNANCY;

ANIMALS; ESTROUS CYCLE; FEMALE; GENE EXPRESSION REGULATION; HYPOTHALAMUS; LEPTIN; PREGNANCY; PREGNANCY, ANIMAL; RECEPTORS, LEPTIN;

SUS;

EID: 73149123565     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2008.01118.x     Document Type: Article

References (33)

1. Barb CR, Kraeling RR, Barrett JB, Rampacek GB, 1999 : Role of leptin in modulating neuroendocrine function: a metabolic link between the brain-pituitary and adipose tissue. Reprod Dom Anim 34, 111 125.
2. Barb CR, Hausman GJ, Czaja K, 2005 : Leptin: a metabolic signal affecting central regulation of reproduction in the pig. Domest Anim Endocrinol 29, 186 192.
3. Bennett PA, Lindell K, Karlsson C, Robinson IC, Carlsson LM, Carlsson B, 1998 : Differential expression and regulation of leptin receptor isoforms in the rat brain: effects of fasting and oestrogen. Neuroendocrinology 76, 29 36.
4. Bogacka I, Przala J, Siawrys G, Kaminski T, Smolinska N, 2006 : The expression of short form of leptin receptor gene during early pregnancy in the pig examined by quantitative real time RT-PCR. J Physiol Pharmacol 57, 479 489.
5. Burguera B, Couce ME, Long J, Lamsam J, Laakso K, Jensen MD, Parisi JE, Lloyd RV, 2000 : The long form of the leptin receptor (OB-Rb) is widely expressed in the human brain. Neuroendocrinology 71, 187 195.
6. Caprio M, Fabbrini E, Isidori AM, Aversa A, Fabbri A, 2001 : Leptin in reproduction. Trend Endocrinol Metab 12, 65 72.
7. del Carmen Garcia M, Casanueva FF, Dieguez C, Senaris RM, 2000 : Gestational profile of leptin messenger ribonucleic acid (mRNA) content in the placenta and adipose tissue in the rat, and regulation of mRNA levels of the leptin receptor subtypes in the hypothalamus during pregnancy and lactation. Biol Reprod 62, 698 703.
8. Chelikani PK, Glimm DR, Kennelly JJ, 2003 : Short communication: tissue distribution of leptin and leptin receptor mRNA in the bovine. J Dairy Sci 86, 2369 2372.
9. Czaja K, Łakomy M, Sienkiewicz W, Kaleczyc J, Pisudko Z, Barb CR, Rampacek GB, Kraeling RR, 2002 : Distribution of neurons containing leptin receptors in the hypothalamus of the pig. Biochem Biophys Res Commun 298, 333 337. (Pubitemid 35333709)
10. Diano S, Kalra SP, Sakamoto H, Horvath TL, 1998 : Leptin receptors in estrogen receptor-containing neurons of the female rat hypothalamus. Brain Res 812, 256 259.
11. Dyer CJ, Simmons JM, Matteri RL, Keisler DH, 1997 : Leptin receptor mRNA is expressed in ewe anterior pituitary and adipose tissues and is diferentially expressed in hypothalamic regions of well-fed and feed-restricted ewes. Domest Anim Endocrinol 14, 119 128.
12. Hakansson ML, Meister B, 1998 : Transcription factor STAT3 in leptin target neurons of the rat hypothalamus. Neuroendocrinology 68, 420 427. (Pubitemid 29000851)
13. Hosoi T, Kawagishi T, Okuma Y, Tanaka J, Nomura Y, 2002 : Brain stem is a direct target for leptin's action in the central nervous system. Endocrinology 143, 3498 3504.
14. Huang L, Wang Z, Li C, 2001 : Modulation of circulating leptin levels by its soluble receptor. J Biol Chem 276, 6343 6349.
15. Iqbal J, Pompolo S, Murakami T, Grouzmann E, Sakurai T, Meister B, Clarke LJ, 2001 : Immunohistochemical characterization of localization of long form leptin receptor (OB-Rb) in neurochemically defined cells in the ovine hypothalamus. Brain Res 920, 55 64.
16. Kaminski T, Smolinska N, Gajewska A, Siawrys G, Okrasa S, Kochman K, Przała J, 2006 : Leptin and long form of leptin receptor genes expression in the hypothalamus and pituitary during the luteal phase and early pregnancy in pig. J Physiol Pharmacol 57, 95 108.
17. Kastin AJ, Pan W, 2000 : Dynamic regulation of leptin entry into brain by the blood-brain barrier. Regul Pept 92, 37 43.
18. Lin J, Barb CR, Matteri RL, Kraeling RR, Chen X, Meinersman RJ, Rampacek GB, 2000 : Long form leptin receptor mRNA expression in the brain, pituitary and other tissues in the pig. Dom Anim Endocrinol 19, 53 61.
19. Lin J, Barb R, Kraeling RK, Rampacek GB, 2001 : Developmental changes in the long form leptin receptor and related neuropeptide gene expression in the pig brain. Biol Reprod 64, 1614 1618.
20. Meli R, Pacilio M, Raso GM, Esposito E, Coppola A, Nasti A, Di CarloC, Nappi C, Di CarloR, 2004 : Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats. Endocrinology 145, 3115 3121.
21. Morash B, Imran A, Wilkinson D, Ur E, Wilkinson M, 2003 : Leptin receptors are developmentally regulated in rat pituitary and hypothalamus. Mol Cell Endocrinol 210, 1 8.
22. Parent AS, Lebrethon MC, Gerard A, Vandersmissen E, Bourguignon JP, 2000 : Leptin effects on pulsatile gonadotropin releasing hormone secretion from the adult rat hypothalamus and interaction with cocaine and amphetamine regulated transcript peptide and neuropeptide Y. Regul Pept 92, 2517 2524.
23. Seeber RM, Smith JT, Waddell BJ, 2002 : Plasma leptin-binding activity and hypothalamic leptin receptor expression during pregnancy and lactation in the rat. Biol Reprod 66, 1762 1767.
24. Sesti LAC, Britt JH, 1993 : Relationship of secretion of GnRH in vitro to changes in pituitary concentrations of LH and FSH and serum concentrations of LH during lactation in sows. J Reprod Fertil 98, 393 400.
25. Siawrys G, Przala J, Kaminski T, Smolinska N, Gajewska A, Kochman K, Skowronski M, Staszkiewicz J, 2005 : Long form leptin receptor mRNA expression in the hypothalamus and pituitary during early pregnancy in the pig. Neuro Endocrinol Lett 26, 305 309.
26. Siawrys G, Kaminski T, Smolinska N, Przala J, 2007 : Expression of leptin and long form of leptin receptor genes and proteins in pituitary of cyclic and pregnant pigs. J Physiol Pharmacol 58, 845 847.
27. Smolinska N, Siawrys G, Kaminski T, Przala J, 2007 : Leptin gene and protein expression in the trophoblast and uterine tissues during early pregnancy and the oestrous cycle of pigs. J Physiol Pharmacol 58, 563 581.
28. Tartaglia LA, Demski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, 1995 : Identification and expression cloning of a leptin receptor OB-R. Cell 83, 1263 1271.
29. Yu WH, Kimura M, Walczewska A, Karanth S, Mc CannSM, 1997 : Role of leptin in hypothalamic-pituitary function. Proc Natl Acad Sci USA 94, 1023 1028.
30. Zamorano PL, Mahesh VB, De SevillaLM, Chorich LP, Bhat GK, Brann DW, 1997 : Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat. Neuroendocrinology 65, 223 228.
31. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM, 1994 : Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425 432.
32. Zieba DA, Amstalden M, Morton S, Maciel MN, Keisler DH, Williams GL, 2004 : Regulatory roles of leptin at the hypothalamic-hypophyseal axis before and after sexual maturation in cattle. Biol Reprod 71, 804 812.
33. Zieba DA, Amstalden M, Williams GL, 2005 : Regulatory roles of leptin in reproduction and metabolism: a comparative review. Domest Anim Endocrinol 29, 166 185.