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Volumn 391, Issue 1, 2010, Pages 739-743

Comparative deacetylase activity of wild type and mutants of SIRT1

Author keywords

Activity; Deacetylation; Drug discovery; Recombinant protein; SIRT1

Indexed keywords

ACYLTRANSFERASE; AMINO ACID; RESVERATROL; SIRTUIN 1; SURAMIN;

EID: 72949112691     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.11.130     Document Type: Article
Times cited : (11)

References (24)
  • 1
    • 0033600176 scopus 로고    scopus 로고
    • Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and might have protein ADP-ribosyltransferase activity
    • Frye R.A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and might have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 260 (1999) 273-279
    • (1999) Biochem. Biophys. Res. Commun. , vol.260 , pp. 273-279
    • Frye, R.A.1
  • 2
    • 67949102053 scopus 로고    scopus 로고
    • Recent progress in the biology and physiology of sirtuins
    • Finkel T., Deng C.X., and Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 460 (2009) 587-591
    • (2009) Nature , vol.460 , pp. 587-591
    • Finkel, T.1    Deng, C.X.2    Mostoslavsky, R.3
  • 4
  • 5
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M., McVey M., and Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13 (1999) 2570-2580
    • (1999) Genes Dev. , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 7
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum H.A., and Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 (2001) 227-230
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 10
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F., Hoberg J.E., Ramsey C.S., Keller M.D., Jones D.R., Frye R.A., and Mayo M.W. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23 (2004) 2369-2380
    • (2004) EMBO J. , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 11
    • 63649125404 scopus 로고    scopus 로고
    • Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition?
    • Jung-Hynes B., Nihal M., Zhong W., and Ahmad N. Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition?. J. Biol. Chem. 284 (2009) 3823-3832
    • (2009) J. Biol. Chem. , vol.284 , pp. 3823-3832
    • Jung-Hynes, B.1    Nihal, M.2    Zhong, W.3    Ahmad, N.4
  • 12
    • 62449178216 scopus 로고    scopus 로고
    • The critical role of the class III histone deacetylase SIRT1 in cancer
    • Liu T., Liu P.Y., and Marshall G.M. The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res. 69 (2009) 1702-1705
    • (2009) Cancer Res. , vol.69 , pp. 1702-1705
    • Liu, T.1    Liu, P.Y.2    Marshall, G.M.3
  • 13
    • 33644943609 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors sit at crossroad of diet, aging and cancer
    • Hede K. Histone deacetylase inhibitors sit at crossroad of diet, aging and cancer. J. Natl. Cancer Inst. 98 (2006) 377-379
    • (2006) J. Natl. Cancer Inst. , vol.98 , pp. 377-379
    • Hede, K.1
  • 16
    • 70350464163 scopus 로고    scopus 로고
    • Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4α
    • Yang J., Kong X., Martins-Santos M.E.S., Aleman G., Chaco E., Liu G.E., Wu S.Y., Samols D., Hakimi P., Chiang C.M., and Hanson R.W. Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4α. J. Biol. Chem. 284 (2009) 27042-27053
    • (2009) J. Biol. Chem. , vol.284 , pp. 27042-27053
    • Yang, J.1    Kong, X.2    Martins-Santos, M.E.S.3    Aleman, G.4    Chaco, E.5    Liu, G.E.6    Wu, S.Y.7    Samols, D.8    Hakimi, P.9    Chiang, C.M.10    Hanson, R.W.11
  • 17
    • 53349091778 scopus 로고    scopus 로고
    • SIRT1 contributes in part to cisplatin resistance in cancer cells by altering mitochondrial metabolism
    • Liang X.J., Finkel T., Shen W., Yin J.J., Aszalos A., and Gottesman M.M. SIRT1 contributes in part to cisplatin resistance in cancer cells by altering mitochondrial metabolism. Mol. Cancer Res. 6 (2008) 1499-1506
    • (2008) Mol. Cancer Res. , vol.6 , pp. 1499-1506
    • Liang, X.J.1    Finkel, T.2    Shen, W.3    Yin, J.J.4    Aszalos, A.5    Gottesman, M.M.6
  • 18
    • 40849135481 scopus 로고    scopus 로고
    • The Sirtuin family: therapeutic targets to treat diseases of aging
    • Milne J.C., and Denu J.M. The Sirtuin family: therapeutic targets to treat diseases of aging. Curr. Opin. Chem. Biol. 12 (2008) 11-17
    • (2008) Curr. Opin. Chem. Biol. , vol.12 , pp. 11-17
    • Milne, J.C.1    Denu, J.M.2
  • 21
    • 44849096876 scopus 로고    scopus 로고
    • The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
    • 10.1371/journal.pone.0002020
    • Firestein R., Blander G., Michan S., Oberdoerffer P., and Ogino S. The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS ONE 3 (2008) e2020 10.1371/journal.pone.0002020
    • (2008) PLoS ONE , vol.3
    • Firestein, R.1    Blander, G.2    Michan, S.3    Oberdoerffer, P.4    Ogino, S.5
  • 22
    • 58849158388 scopus 로고    scopus 로고
    • How does SIRT1 affect metabolism, senescence and cancer?
    • Brooks C.L., and Wei G. How does SIRT1 affect metabolism, senescence and cancer?. Nat. Rev. Cancer 9 (2009) 123-128
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 123-128
    • Brooks, C.L.1    Wei, G.2
  • 23
    • 37249092594 scopus 로고    scopus 로고
    • Cloning, stable expression of human phosphodiesterase 7A and development of an assay for screening of PDE7 selective inhibitors
    • Malik R., Bora R.S., Gupta D., Sharma P., Arya R., Chaudhary S., and Saini K.S. Cloning, stable expression of human phosphodiesterase 7A and development of an assay for screening of PDE7 selective inhibitors. Appl. Microbiol. Biotechnol. 77 (2007) 1167-1173
    • (2007) Appl. Microbiol. Biotechnol. , vol.77 , pp. 1167-1173
    • Malik, R.1    Bora, R.S.2    Gupta, D.3    Sharma, P.4    Arya, R.5    Chaudhary, S.6    Saini, K.S.7
  • 24
    • 38549143777 scopus 로고    scopus 로고
    • Production of active eukaryotic protein through bacterial expression systems: a review of the existing biotechnology strategies
    • Sahdev S., Khattar S.K., and Saini K.S. Production of active eukaryotic protein through bacterial expression systems: a review of the existing biotechnology strategies. Mol. Cell. Biochem. 307 (2008) 249-264
    • (2008) Mol. Cell. Biochem. , vol.307 , pp. 249-264
    • Sahdev, S.1    Khattar, S.K.2    Saini, K.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.