Cloning, stable expression of human phosphodiesterase 7A and development of an assay for screening of PDE7 selective inhibitors

Applied Microbiology and Biotechnology

Volumn 77, Issue 5, 2008, Pages 1167-1173

  Malik, Renu ^a   Bora, Roop Singh ^a   Gupta, Dikshi ^a   Sharma, Pratibha ^a   Arya, Ranjana ^a   Chaudhary, Shiwani ^a   Saini, Kulvinder Singh ^a  

^a RANBAXY RESEARCH LABORATORIES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CLONING; DISEASES; ENZYME ACTIVITY; HYDROLYSIS;

PHOSPHODIESTERASES (PDE); SELECTIVE INHIBITORS;

ENZYME INHIBITION;

COMPLEMENTARY DNA; CYCLIC AMP; CYCLIC GMP; LUCIFERASE; PHOSPHODIESTERASE VII; PHOSPHODIESTERASE VII INHIBITOR;

BIOASSAY; CATALYSIS; DISEASE TREATMENT; ENZYME ACTIVITY; GENE EXPRESSION; HYDROLYSIS; INHIBITOR; PLASMID;

ARTICLE; CATALYSIS; CELL STRAIN HEK293; EMBRYO; ENZYME ASSAY; ENZYME STABILITY; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOCYTOCHEMISTRY; PLASMID; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; WESTERN BLOTTING;

CELL LINE; CLONING, MOLECULAR; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 7; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; GENES, REPORTER; HUMANS; LUCIFERASES; PHOSPHODIESTERASE INHIBITORS;

EID: 37249092594     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-007-1230-3     Document Type: Article

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