New cytochrome P450 mechanisms: Implications for understanding molecular basis for drug toxicity at the level of the cytochrome

Expert Opinion on Drug Metabolism and Toxicology

Volumn 6, Issue 1, 2010, Pages 1-15

  Shakunthala, Narasimhulu ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NONE   (Philippines)

Author keywords

Coupling uncoupling; CYP; Drug toxicity; Product; Substrate

Indexed keywords

CAMPHOR; CYTOCHROME P450; FERRIC ION;

ALLOSTERISM; BIOREMEDIATION; CROSS COUPLING REACTION; CRYSTALLOGRAPHY; HUMAN; PROTEIN BINDING; PROTEIN INTERACTION; REVIEW;

ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; HEME; HUMANS; IRON; PHARMACEUTICAL PREPARATIONS; PHARMACOGENETICS; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 72949090555     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425250903329095     Document Type: Review

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