PIP2-binding site in Kir channels: Definition by multiscale biomolecular simulations

Biochemistry

Volumn 48, Issue 46, 2009, Pages 10926-10933

  Stansfeld, Phillip J ^a   Hopkinson, Richard ^a   Ashcroft, Frances M ^b   Sansom, Mark S P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMISTIC MOLECULAR DYNAMICS; ATOMISTIC REPRESENTATION; ATOMISTIC SIMULATIONS; BIOMOLECULAR SIMULATION; BISPHOSPHATES; CHANNEL COMPLEX; CHANNEL STRUCTURES; COARSE-GRAINED; DETERGENT MOLECULES; H-BONDING INTERACTION; HOMOLOGY MODELS; INNER LEAFLETS; LIPID BILAYER MEMBRANES; MOLECULAR DYNAMICS SIMULATIONS; MULTI-SCALE SIMULATION; MULTISCALES; N-TERMINALS; PHOSPHATIDYLINOSITOL; SEQUENTIAL COMBINATION; SIDE CHAINS; THREE CHANNEL; X-RAY STRUCTURE;

BINDING ENERGY; DISTILLATION; LIPID BILAYERS; MAMMALS; MOLECULAR DYNAMICS; POTASSIUM; SIMULATORS;

BINDING SITES;

INWARDLY RECTIFYING POTASSIUM CHANNEL; TRIPHOSPHOINOSITIDE;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; LIPID BILAYER; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SIMULATION; STRUCTURE ANALYSIS; X RAY ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BINDING SITES; BURKHOLDERIA PSEUDOMALLEI; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HYDROGEN BONDING; LIPID BILAYERS; MICE; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT;

MAMMALIA;

EID: 72749123748     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9013193     Document Type: Article

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