Metabolic hormones, dopamine circuits, and feeding

Frontiers in Neuroendocrinology

Volumn 31, Issue 1, 2010, Pages 104-112

  Narayanan, Nandakumar S ^a   Guarnieri, Douglas J ^a   DiLeone, Ralph J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dopamine; Leptin; Midbrain; Nucleus accumbens; Obesity; Prefrontal cortex; Striatum; Ventral tegmental area

Indexed keywords

DOPAMINE; HORMONE;

BRAIN FUNCTION; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; FEEDING BEHAVIOR; FOOD INTAKE; GENE DELETION; GENE TARGETING; HUMAN; MESENCEPHALON; MESOLIMBIC DOPAMINERGIC SYSTEM; NERVE CELL NETWORK; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; REVIEW; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

ANIMALS; CORPUS STRIATUM; DOPAMINE; EATING; GHRELIN; HUMANS; LEPTIN; NEURONS; NUCLEUS ACCUMBENS; PEPTIDE HORMONES; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; VENTRAL TEGMENTAL AREA;

EID: 72449155495     PISSN: 00913022     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yfrne.2009.10.004     Document Type: Review

References (145)

1. Abizaid A., Liu Z.W., Andrews Z.B., Shanabrough M., Borok E., Elsworth J.D., Roth R.H., Sleeman M.W., Picciotto M.R., Tschop M.H., Gao X.B., and Horvath T.L. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. J. Clin. Invest. 116 (2006) 3229-3239
2. Ashford J., and Jones B.J. The effects of intra-amygdaloid injections of 6-hydroxy-dopamine on avoidance responding in rats. Brit. J. Pharmacol. 56 (1976) 255-261
3. Bachmann C.G., and Trenkwalder C. Body weight in patients with Parkinson's disease. Mov. Disord. 21 (2006) 1824-1830
4. Baez L.A., Ahlskog J.E., and Randall P.K. Body weight and regulatory deficits following unilateral nigrostriatal lesions. Brain Res. 132 (1977) 467-476
5. Bakshi V.P., and Kelley A.E. Feeding induced by opioid stimulation of the ventral striatum: role of opiate receptor subtypes. J. Pharmacol. Exp. Ther. 265 (1993) 1253-1260
6. Baldo B.A., Sadeghian K., Basso A.M., and Kelley A.E. Effects of selective dopamine D1 or D2 receptor blockade within nucleus accumbens subregions on ingestive behavior and associated motor activity. Behav. Brain Res. 137 (2002) 165-177
7. Balleine B.W. Neural bases of food-seeking: affect, arousal and reward in corticostriatolimbic circuits. Physiol. Behav. 86 (2005) 717-730
8. Bassareo V., and Di Chiara G. Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments. Neuroscience 89 (1999) 637-641
9. Basso A.M., and Kelley A.E. Feeding induced by GABA(A) receptor stimulation within the nucleus accumbens shell: regional mapping and characterization of macronutrient and taste preference. Behav. Neurosci. 113 (1999) 324-336
10. Berridge K.C. The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology (Berl) 191 (2007) 391-431
11. Bogerts B., Hantsch J., and Herzer M. A morphometric study of the dopamine-containing cell groups in the mesencephalon of normals, Parkinson patients, and schizophrenics. Biol. Psychiatry 18 (1983) 951-969
12. Campfield L.A., Smith F.J., Guisez Y., Devos R., and Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269 (1995) 546-549
13. Cannon C.M., and Bseikri M.R. Is dopamine required for natural reward?. Physiol. Behav. 81 (2004) 741-748
14. Cannon C.M., and Palmiter R.D. Reward without dopamine. J. Neurosci. 23 (2003) 10827-10831
15. Carr D.B., and Sesack S.R. GABA-containing neurons in the rat ventral tegmental area project to the prefrontal cortex. Synapse 38 (2000) 114-123
16. Chuhma N., Zhang H., Masson J., Zhuang X., Sulzer D., Hen R., and Rayport S. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. J. Neurosci. 24 (2004) 972-981
17. Church W.H., Justice Jr. J.B., and Neill D.B. Detecting behaviorally relevant changes in extracellular dopamine with microdialysis. Brain Res. 412 (1987) 397-399
18. Corrigall W.A., Franklin K.B., Coen K.M., and Clarke P.B. The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology (Berl) 107 (1992) 285-289
19. Dal Bo G., St-Gelais F., Danik M., Williams S., Cotton M., and Trudeau L.E. Dopamine neurons in culture express VGLUT2 explaining their capacity to release glutamate at synapses in addition to dopamine. J. Neurochem. 88 (2004) 1398-1405
20. Damier P., Hirsch E.C., Agid Y., and Graybiel A.M. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain 122 Pt 8 (1999) 1437-1448
21. Damier P., Hirsch E.C., Agid Y., and Graybiel A.M. The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D (28K) immunohistochemistry. Brain 122 Pt 8 (1999) 1421-1436
22. Delgado J.M., and Anand B.K. Increase of food intake induced by electrical stimulation of the lateral hypothalamus. Am. J. Physiol. 172 (1953) 162-168
23. Durrieu G., ME L.L., Rascol O., Senard J.M., Rascol A., and Montastruc J.L. Parkinson's disease and weight loss: a study with anthropometric and nutritional assessment. Clin. Auton. Res. 2 (1992) 153-157
24. Elmquist J.K., Elias C.F., and Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22 (1999) 221-232
25. Fallon S., Shearman E., Sershen H., and Lajtha A. Food reward-induced neurotransmitter changes in cognitive brain regions. Neurochem. Res. 32 (2007) 1772-1782
26. Figlewicz D.P. Adiposity signals and food reward: expanding the CNS roles of insulin and leptin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284 (2003) R882-R892
27. Figlewicz D.P., Evans S.B., Murphy J., Hoen M., and Baskin D.G. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Res. 964 (2003) 107-115
28. Fitzgerald P., and Dinan T.G. Prolactin and dopamine: what is the connection? A review article. J. Psychopharmacol. 22 (2008) 12-19
29. Friedman J.M., and Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 395 (1998) 763-770
30. Fulton S., Pissios P., Manchon R.P., Stiles L., Frank L., Pothos E.N., Maratos-Flier E., and Flier J.S. Leptin regulation of the mesoaccumbens dopamine pathway. Neuron 51 (2006) 811-822
31. Gabbott P.L., Warner T.A., Jays P.R., Salway P., and Busby S.J. Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers. J. Comp. Neurol. 492 (2005) 145-177
32. Galey D., Simon H., and Le Moal M. Behavioral effects of lesions in the A10 dopaminergic area of the rat. Brain Res. 124 (1977) 83-97
33. Garzon M., and Pickel V.M. Plasmalemmal mu-opioid receptor distribution mainly in nondopaminergic neurons in the rat ventral tegmental area. Synapse 41 (2001) 311-328
34. Georgescu D., Sears R.M., Hommel J.D., Barrot M., Bolanos C.A., Marsh D.J., Bednarek M.A., Bibb J.A., Maratos-Flier E., Nestler E.J., and DiLeone R.J. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. J. Neurosci. 25 (2005) 2933-2940
35. Girault J.A., and Greengard P. The neurobiology of dopamine signaling. Arch. Neurol. 61 (2004) 641-644
36. Gold R.M. Aphagia and adipsia produced by unilateral hypothalamic lesions in rats. Am. J. Physiol. 211 (1966) 1274-1276
37. Goto Y., Otani S., and Grace A.A. The Yin and Yang of dopamine release: a new perspective. Neuropharmacology 53 (2007) 583-587
38. Grace A.A. Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia. Neuroscience 41 (1991) 1-24
39. Greengard P. The neurobiology of slow synaptic transmission. Science 294 (2001) 1024-1030
40. Gudelsky G.A. Tuberoinfundibular dopamine neurons and the regulation of prolactin secretion. Psychoneuroendocrinology 6 (1981) 3-16
41. Hajnal A., and Lenard L. Feeding-related dopamine in the amygdala of freely moving rats. NeuroReport 8 (1997) 2817-2820
42. Halaas J.L., Gajiwala K.S., Maffei M., Cohen S.L., Chait B.T., Rabinowitz D., Lallone R.L., Burley S.K., and Friedman J.M. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269 (1995) 543-546
43. Hernandez L., and Hoebel B.G. Feeding and hypothalamic stimulation increase dopamine turnover in the accumbens. Physiol. Behav. 44 (1988) 599-606
44. Hernandez L., and Hoebel B.G. Feeding can enhance dopamine turnover in the prefrontal cortex. Brain Res. Bull. 25 (1990) 975-979
45. Hodge G.K., and Butcher L.L. Pars compacta of the substantia nigra modulates motor activity but is not involved importantly in regulating food and water intake. Naunyn. Schmiedebergs Arch. Pharmacol. 313 (1980) 51-67
46. Holland P.C., and Petrovich G.D. A neural systems analysis of the potentiation of feeding by conditioned stimuli. Physiol. Behav. 86 (2005) 747-761
47. Holland P.C., Petrovich G.D., and Gallagher M. The effects of amygdala lesions on conditioned stimulus-potentiated eating in rats. Physiol. Behav. 76 (2002) 117-129
48. Hommel J.D., Sears R.M., Georgescu D., Simmons D.L., and DiLeone R.J. Local gene knockdown in the brain using viral-mediated RNA interference. Nat. Med. 9 (2003) 1539-1544
49. Hommel J.D., Trinko R., Sears R.M., Georgescu D., Liu Z.W., Gao X.B., Thurmon J.J., Marinelli M., and DiLeone R.J. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron 51 (2006) 801-810
50. Hornykiewicz O. Basic research on dopamine in Parkinson's disease and the discovery of the nigrostriatal dopamine pathway: the view of an eyewitness. Neurodegener. Dis. 5 (2008) 114-117
51. Hyland B.I., Reynolds J.N., Hay J., Perk C.G., and Miller R. Firing modes of midbrain dopamine cells in the freely moving rat. Neuroscience 114 (2002) 475-492
52. Ingalls A.M., Dickie M.M., and Snell G.D. Obese, a new mutation in the house mouse. J. Hered. 41 (1950) 317-318
53. Ishiwari K., Weber S.M., Mingote S., Correa M., and Salamone J.D. Accumbens dopamine and the regulation of effort in food-seeking behavior: modulation of work output by different ratio or force requirements. Behav. Brain Res. 151 (2004) 83-91
54. Johnson S.W., and North R.A. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J. Neurosci. 12 (1992) 483-488
55. Kelley A.E. Functional specificity of ventral striatal compartments in appetitive behaviors. Ann. NY Acad. Sci. 877 (1999) 71-90
56. Kelley A.E. Ventral striatal control of appetitive motivation: role in ingestive behavior and reward-related learning. Neurosci. Biobehav. Rev. 27 (2004) 765-776
57. Kelley A.E., Baldo B.A., Pratt W.E., and Will M.J. Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward. Physiol. Behav. 86 (2005) 773-795
58. Koob G.F., Riley S.J., Smith S.C., and Robbins T.W. Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity, and amphetamine anorexia in the rat. J. Comp. Physiol. Psychol. 92 (1978) 917-927
59. Koob G.F., Stinus L., and Le Moal M. Hyperactivity and hypoactivity produced by lesions to the mesolimbic dopamine system. Behav. Brain Res. 3 (1981) 341-359
60. Lammel S., Hetzel A., Hackel O., Jones I., Liss B., and Roeper J. Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron 57 (2008) 760-773
61. Lapish C.C., Seamans J.K., and Chandler L.J. Glutamate-dopamine cotransmission and reward processing in addiction. Alcohol Clin. Exp. Res. 30 (2006) 1451-1465
62. Lapish C.C., Kroener S., Durstewitz D., Lavin A., and Seamans J.K. The ability of the mesocortical dopamine system to operate in distinct temporal modes. Psychopharmacology (Berl) 191 (2007) 609-625
63. Lavin A., Nogueira L., Lapish C.C., Wightman R.M., Phillips P.E., and Seamans J.K. Mesocortical dopamine neurons operate in distinct temporal domains using multimodal signaling. J. Neurosci. 25 (2005) 5013-5023
64. Ljungberg T., Apicella P., and Schultz W. Responses of monkey dopamine neurons during learning of behavioral reactions. J. Neurophysiol. 67 (1992) 145-163
65. MacDonald A.F., Billington C.J., and Levine A.S. Alterations in food intake by opioid and dopamine signaling pathways between the ventral tegmental area and the shell of the nucleus accumbens. Brain Res. 1018 (2004) 78-85
66. Maldonado-Irizarry C.S., Swanson C.J., and Kelley A.E. Glutamate receptors in the nucleus accumbens shell control feeding behavior via the lateral hypothalamus. J. Neurosci. 15 (1995) 6779-6788
67. Margules D.L., and Olds J. Identical "feeding" and "rewarding" systems in the lateral hypothalamus of rats. Science 135 (1962) 374-375
68. Marshall J.F., Berrios N., and Sawyer S. Neostriatal dopamine and sensory inattention. J. Comp. Physiol. Psychol. 94 (1980) 833-846
69. Martin-Iverson M.T., Szostak C., and Fibiger H.C. 6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence intravenous self-administration of cocaine. Psychopharmacology (Berl) 88 (1986) 310-314
70. Mendez J.A., Bourque M.J., Dal Bo G., Bourdeau M.L., Danik M., Williams S., Lacaille J.C., and Trudeau L.E. Developmental and target-dependent regulation of vesicular glutamate transporter expression by dopamine neurons. J. Neurosci. 28 (2008) 6309-6318
71. Mirenowicz J., and Schultz W. Importance of unpredictability for reward responses in primate dopamine neurons. J. Neurophysiol. 72 (1994) 1024-1027
72. Mogenson G.J., and Wu M. Neuropharmacological and electrophysiological evidence implicating the mesolimbic dopamine system in feeding responses elicited by electrical stimulation of the medial forebrain bundle. Brain Res. 253 (1982) 243-251
73. Mucha R.F., and Iversen S.D. Increased food intake after opioid microinjections into nucleus accumbens and ventral tegmental area of rat. Brain Res. 397lco (1986) 214-224
74. Myers Jr. M.G., Munzberg H., Leinninger G.M., and Leshan R.L. The geometry of leptin action in the brain: more complicated than a simple ARC. Cell Metab. 9 (2009) 117-123
75. Nadaud D., Simon H., Herman J.P., and Le Moal M. Contributions of the mesencephalic dopaminergic system and the trigeminal sensory pathway to the ventral tegmental aphagia syndrome in rats. Physiol. Behav. 33 (1984) 879-887
76. Nagai T., McGeer P.L., and McGeer E.G. Distribution of GABA-T-intensive neurons in the rat forebrain and midbrain. J. Comp. Neurol. 218 (1983) 220-238
77. Nakazato M., Murakami N., Date Y., Kojima M., Matsuo H., Kangawa K., and Matsukura S. A role for ghrelin in the central regulation of feeding. Nature 409 (2001) 194-198
78. Naleid A.M., Grace M.K., Cummings D.E., and Levine A.S. Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides 26 (2005) 2274-2279
79. Narayanan N.S., and Laubach M. Methods for studying functional interactions among neuronal populations. Meth. Mol. Biol. 489 (2009) 135-165
80. Nauta W.J., Smith G.P., Faull R.L., and Domesick V.B. Efferent connections and nigral afferents of the nucleus accumbens septi in the rat. Neuroscience 3 (1978) 385-401
81. Nencini P., and Stewart J. Chronic systemic administration of amphetamine increases food intake to morphine, but not to U50-488H, microinjected into the ventral tegmental area in rats. Brain Res. 527 (1990) 254-258
82. Nicola S.M., Surmeier J., and Malenka R.C. Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens. Ann. Rev. Neurosci. 23 (2000) 185-215
83. Nishino H., Hattori S., Muramoto K., and Ono T. Basal ganglia neural activity during operant feeding behavior in the monkey: relation to sensory integration and motor execution. Brain Res. Bull. 27 (1991) 463-468
84. Nugent F.S., and Kauer J.A. LTP of GABAergic synapses in the ventral tegmental area and beyond. J. Physiol. 586 (2008) 1487-1493
85. Oades R.D., and Halliday G.M. Ventral tegmental (A10) system: neurobiology. 1. Anatomy and connectivity. Brain Res. 434 (1987) 117-165
86. Pagnoni G., Zink C.F., Montague P.R., and Berns G.S. Activity in human ventral striatum locked to errors of reward prediction. Nat. Neurosci. 5 (2002) 97-98
87. Palmiter R.D. Is dopamine a physiologically relevant mediator of feeding behavior?. Trends Neurosci. 30 (2007) 375-381
88. Palmiter R.D. Dopamine signaling in the dorsal striatum is essential for motivated behaviors: lessons from dopamine-deficient mice. Ann. NY Acad. Sci. 1129 (2008) 35-46
89. Papp M., and Bal A. Motivational versus motor impairment after haloperidol injection or 6-OHDA lesions in the ventral tegmental area or substantia nigra in rats. Physiol. Behav. 38 (1986) 773-779
90. Papp M., and Bal A. Separation of the motivational and motor consequences of 6-hydroxydopamine lesions of the mesolimbic or nigrostriatal system in rats. Behav. Brain Res. 23 (1987) 221-229
91. Petreanu L., Huber D., Sobczyk A., and Svoboda K. Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections. Nat. Neurosci. 10 (2007) 663-668
92. Petrovich G.D., Ross C.A., Holland P.C., and Gallagher M. Medial prefrontal cortex is necessary for an appetitive contextual conditioned stimulus to promote eating in sated rats. J. Neurosci. 27 (2007) 6436-6441
93. Phillips A.G., and Nikaido R.S. Disruption of brain stimulation-induced feeding by dopamine receptor blockade. Nature 258 (1975) 750-751
94. Pioli E.Y., Meissner W., Sohr R., Gross C.E., Bezard E., and Bioulac B.H. Differential behavioral effects of partial bilateral lesions of ventral tegmental area or substantia nigra pars compacta in rats. Neuroscience 153 (2008) 1213-1224
95. Price M.T., and Fibiger H.C. Discriminated escape learning and response to electric shock after 6-hydroxydopamine lesions of the nigro-neostriatal dopaminergic projection. Pharmacol. Biochem. Behav. 3 (1975) 285-290
96. Roberts D.C., Corcoran M.E., and Fibiger H.C. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmacol. Biochem. Behav. 6 (1977) 615-620
97. Roitman M.F., Stuber G.D., Phillips P.E., Wightman R.M., and Carelli R.M. Dopamine operates as a subsecond modulator of food seeking. J. Neurosci. 24 (2004) 1265-1271
98. Romo R., and Schultz W. Dopamine neurons of the monkey midbrain: contingencies of responses to active touch during self-initiated arm movements. J. Neurophysiol. 63 (1990) 592-606
99. Roth B.L., Craigo S.C., Choudhary M.S., Uluer A., Monsma Jr. F.J., Shen Y., Meltzer H.Y., and Sibley D.R. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther. 268 (1994) 1403-1410
100. Salamone J.D., Mahan K., and Rogers S. Ventrolateral striatal dopamine depletions impair feeding and food handling in rats. Pharmacol. Biochem. Behav. 44 (1993) 605-610
101. Salamone J.D., Correa M., Mingote S., and Weber S.M. Nucleus accumbens dopamine and the regulation of effort in food-seeking behavior: implications for studies of natural motivation, psychiatry, and drug abuse. J. Pharmacol. Exp. Ther. 305 (2003) 1-8
102. Salamone J.D., Correa M., Farrar A., and Mingote S.M. Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits. Psychopharmacology (Berl) 191 (2007) 461-482
103. Schultz W. Dopamine neurons and their role in reward mechanisms. Curr. Opin. Neurobiol. 7 (1997) 191-197
104. Schultz W. Reward signaling by dopamine neurons. Neuroscientist 7 (2001) 293-302
105. Schultz W. Behavioral dopamine signals. Trends Neurosci. 30 (2007) 203-210
106. Schultz W., and Romo R. Dopamine neurons of the monkey midbrain: contingencies of responses to stimuli eliciting immediate behavioral reactions. J. Neurophysiol. 63 (1990) 607-624
107. Schultz W., Apicella P., and Ljungberg T. Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task. J. Neurosci. 13 (1993) 900-913
108. Schultz W., Dayan P., and Montague P.R. A neural substrate of prediction and reward. Science 275 (1997) 1593-1599
109. Schwartz M.W. Central nervous system regulation of food intake. Obesity (Silver Spring) 14 Suppl. 1 (2006) 1S-8S
110. R.M. Sears, R.J. Liu, N.S. Nandakumar, R. Sharf, M.F. Yeckel, E. Maratos-Flier, M. Laubach, G.K. Aghajanian, R.J. DiLeone, Mechanisms underlying a neuropeptide-mediated hypothalamic-limbic feeding circuit. Submitted for publication.
111. Segall M.A., and Margules D.L. Central mediation of naloxone-induced anorexia in the ventral tegmental area. Behav. Neurosci. 103 (1989) 857-864
112. Small D.M., Jones-Gotman M., and Dagher A. Feeding-induced dopamine release in dorsal striatum correlates with meal pleasantness ratings in healthy human volunteers. NeuroImage 19 (2003) 1709-1715
113. Smith G.P. Accumbens dopamine is a physiological correlate of the rewarding and motivating effects of food. In: Stricker E.M., and Woods S.C. (Eds). Neurobiology of Food and Fluid Intake New York (2004), Springer, New York 15-42
114. Smith G.P., Strohmayer A.J., and Reis D.J. Effect of lateral hypothalamic injections of 6-hydroxydopamine on food and water intake in rats. Nat. New Biol. 235 (1972) 27-29
115. Steffensen S.C., Svingos A.L., Pickel V.M., and Henriksen S.J. Electrophysiological characterization of GABAergic neurons in the ventral tegmental area. J. Neurosci. 18 (1998) 8003-8015
116. Stratford T.R., and Kelley A.E. GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior. J. Neurosci. 17 (1997) 4434-4440
117. Stricker E.M., and Zigmond M.J. Brain catecholamines and the central control of food intake. Int. J. Obes. 8 Suppl. 1 (1984) 39-50
118. Svingos A.L., Garzon M., Colago E.E., and Pickel V.M. Mu-opioid receptors in the ventral tegmental area are targeted to presynaptically and directly modulate mesocortical projection neurons. Synapse 41 (2001) 221-229
119. Szczypka M.S., Kwok K., Brot M.D., Marck B.T., Matsumoto A.M., Donahue B.A., and Palmiter R.D. Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice. Neuron 30 (2001) 819-828
120. Trojniar W., and Staszewska M. Unilateral damage to the ventral tegmental area facilitates feeding induced by stimulation of the contralateral ventral tegmental area. Brain Res. 641 (1994) 333-340
121. Trojniar W., Plucinska K., Ignatowska-Jankowska B., and Jankowski M. Damage to the nucleus accumbens shell but not core impairs ventral tegmental area stimulation-induced feeding. J. Physiol. Pharmacol. 58 Suppl. 3 (2007) 63-71
122. Tsai H.C., Zhang F., Adamantidis A., Stuber G.D., Bonci A., de Lecea L., and Deisseroth K. Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science 324 (2009) 1080-1084
123. Ungerstedt U. 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. Eur. J. Pharmacol. 5 (1968) 107-110
124. Ungerstedt U. Adipsia and aphagia after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system. Acta Physiol. Scand. 367 Suppl. (1971) 95-122
125. Vijayraghavan S., Wang M., Birnbaum S.G., Williams G.V., and Arnsten A.F. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nat. Neurosci. 10 (2007) 376-384
126. Volkow N.D., and Wise R.A. How can drug addiction help us understand obesity?. Nat. Neurosci. 8 (2005) 555-560
127. Volkow N.D., Wang G.J., Fowler J.S., Logan J., Jayne M., Franceschi D., Wong C., Gatley S.J., Gifford A.N., Ding Y.S., and Pappas N. "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse 44 (2002) 175-180
128. Wang G.J., Volkow N.D., Logan J., Pappas N.R., Wong C.T., Zhu W., Netusil N., and Fowler J.S. Brain dopamine and obesity. Lancet 357 (2001) 354-357
129. Weissenborn R., and Winn P. Regulatory behaviour, exploration and locomotion following NMDA or 6-OHDA lesions in the rat nucleus accumbens. Behav. Brain Res. 51 (1992) 127-137
130. Williams G.V., and Castner S.A. Under the curve: critical issues for elucidating D1 receptor function in working memory. Neuroscience 139 (2006) 263-276
131. Wise R.A. Neurobiology of addiction. Curr. Opin. Neurobiol. 6 (1996) 243-251
132. Wise R.A. Dopamine, learning and motivation. Nat. Rev. Neurosci. 5 (2004) 483-494
133. Wise R.A. Role of brain dopamine in food reward and reinforcement. Philos. Trans. R Soc. Lond. B Biol. Sci. 361 (2006) 1149-1158
134. Wise R.A., and Colle L.M. Pimozide attenuates free feeding: best scores analysis reveals a motivational deficit. Psychopharmacology (Berl) 84 (1984) 446-451
135. Wise R.A., Spindler J., deWit H., and Gerberg G.J. Neuroleptic-induced "anhedonia" in rats: pimozide blocks reward quality of food. Science 201 (1978) 262-264
136. Wise R.A., Spindler J., and Legault L. Major attenuation of food reward with performance-sparing doses of pimozide in the rat. Can. J. Psychol. 32 (1978) 77-85
137. Wisman L.A., Sahin G., Maingay M., Leanza G., and Kirik D. Functional convergence of dopaminergic and cholinergic input is critical for hippocampus-dependent working memory. J. Neurosci. 28 (2008) 7797-7807
138. Wolterink G., Phillips G., Cador M., Donselaar-Wolterink I., Robbins T.W., and Everitt B.J. Relative roles of ventral striatal D1 and D2 dopamine receptors in responding with conditioned reinforcement. Psychopharmacology (Berl) 110 (1993) 355-364
139. Yamamoto T. Neural substrates for the processing of cognitive and affective aspects of taste in the brain. Arch. Histol. Cytol. 69 (2006) 243-255
140. Yavich L., and MacDonald E. Dopamine release from pharmacologically distinct storage pools in rat striatum following stimulation at frequency of neuronal bursting. Brain Res. 870 (2000) 73-79
141. Zhang F., Wang L.P., Boyden E.S., and Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nat. Methods 3 (2006) 785-792
142. Zhou Q.Y., and Palmiter R.D. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 83 (1995) 1197-1209
143. Zigmond M.J., and Stricker E.M. Deficits in feeding behavior after intraventricular injection of 6-hydroxydopamine in rats. Science 177 (1972) 1211-1214
144. Zigmond M.J., and Stricker E.M. Recovery of feeding and drinking by rats after intraventricular 6-hydroxydopamine or lateral hypothalamic lesions. Science 182 (1973) 717-720
145. Zorrilla E.P., Inoue K., Fekete E.M., Tabarin A., Valdez G.R., and Koob G.F. Measuring meals: structure of prandial food and water intake of rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 (2005) R1450-R1467