Plasma homocysteine levels elevated and inversely related to insulin sensitivity in preeclampsia

Obstetrics and Gynecology

Volumn 93, Issue 4 SUPPL., 1999, Pages 489-493

  Laivuori, Hannele ^a   Kaaja, Risto ^a   Turpeinen, Ursula ^a   Viinikka, Lasse ^a   Ylikorkala, Olavi ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; GLUCOSE; HOMOCYSTEINE; INSULIN; UNCLASSIFIED DRUG; VELOSULIN HUMAN;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; ATHEROSCLEROSIS; BIRTH WEIGHT; BLOOD PRESSURE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLIC ACID BLOOD LEVEL; GESTATIONAL AGE; GLUCOSE TOLERANCE TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INSULIN SENSITIVITY; PREECLAMPSIA; PRIORITY JOURNAL; PROTEINURIA; PUERPERIUM; VITAMIN BLOOD LEVEL; WEIGHT GAIN;

ADULT; FEMALE; HOMOCYSTEINE; HUMANS; INSULIN RESISTANCE; PRE-ECLAMPSIA; PREGNANCY;

EID: 0033049262     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006250-199904000-00004     Document Type: Article

References (26)

1. Stampfer MJ, Malinov MR, Willet WC, Newcomer LM, Upson B, Ullman D, et al. A prospective study of plasma homocyst(e)ine and risk of myocardial intarvtion in US physicians. JAMA 1992;268:877-81.
2. Graham IM, Daly LE, Refsum HM, Robinson K, Brattsröm LA, Ueland PM, et al. Plasma homocysteine as a risk factor for vascular disease: The European Concerted Action Project. JAMA 1997;277:1775-81.
3. Welch GN, Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med 1998;338:1042-50.
4. Roberts JM, Redman CW. Pre-eclampsia: More than pregnancy-induced hypertension. Lancet 1993;341:1447-51.
5. Rajkovic A, Catalano PM, Malinow RM. Elevated homocyst(e)ine levels with preeclampsia. Obstet Gynecol 1997;90-168-71
6. Dekker GA, de Vries JIP, Doelitzsch PM, Huijgens PC, von Blomberg BME, Jakobs C, et al. Underlying disorders associated with severe early-onset preeclampsia. Am J Obstet Gynecol 1995, 173:1042-8.
7. Goddijn-Wessel TAW, Wouters MGAJ, vd Molen EF, Spuijbroek MDEH, Steegers-Theunissen RPM, Blom HJ, et al. Hyperhomocysteinemia: A risk factor for placental abruption or infarction. Eur J Obstet Gynecol Reprod Biol 1996;66:23-9.
8. Owen EP, Human L, Carolissen AA, Harley EH, Odendaal HJ. Hyperhomucysteinomia - A risk factor for abruptio placentae. J Inherit Metab Dis 1997;20:359-62.
9. Sowers JR, Saleh AA, Sokol RJ. Hyperinsulmemia and insulin resistance are associated with preeclampsia in African-Americans. Am J Hypertens 1995;8:1-4.
10. Laivuori H, Tikkanen MJ, Ylikorkala O, Hyperinsulinemia 17 years after preeclamptic first pregnacy. J Clin Endocrinol Metab 1996;81:2908-11.
11. Laivuori H, Kaaja R, Rutanen E-M, Viinikka E, Ylikorkala O. Evidence of high circulating testosterone in women with prior preeclampsia. J Clin Endocrinol Metab 1988;83:344-7.
12. Jónsdóttir ES, Arngrimsson R, Geirsson RT, Sigvaldason H, Sigfússon N. Death rates from ischemic heart disease in women with a history of hypertension in pregnancy. Acta Obstet Gynecol Scand 1995;74:772-6.
13. Hannaford P, Ferry S, Hirsch S. Cardiovascular sequelae of toxemia of pregnancy. Heart 1997;77:154-8.
14. Bergman RN. Toward physiological understanding of glucose intolerance. Minimal model approach. Diabetes 1989;38:1512-27.
15. Jacobsen DW, Gatautis VJ, Green R, Robinson K, Savon SR, Secic M, et al. Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: Sex differences and correlation with cobalamin and folate concentrations in healthy subjects. Clin Chem 1994;40-873-81.
16. Daskalakis I, Lucock MD, Anderson A, Wild J, Schorah CJ, Levene MI. Determination of plasma total homocysteine and cysteine using HPLC with fluorescence detection and an ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulphonate (SBD-F) derivatization protocol optimized for antioxidant concentration, derivatization reagent concentration, temperature and matrix pH. Biomed Chromatogr 1996;10:205-12.
17. Ueland P, Refsum H, Stabler S, Malinow R, Andersson A, Allen R. Total homocysteine in plasma or serum: Methods and clinical applications. Clin Chem 1993;39:1764-79.
18. Wilcken DE, Gupta VJ. Sulphur containing amino acids in chronic renal failure with particular reference to homocystine and cysteine-homocysteine mixed disulphide. Eur J Clin Invest 1979;9:301-7.
19. Chauveau P, Chadefaux B, Coude M, Aupetit J, Hannedouche T, Kamoun P, et al. Hyperhomocysteinemia, a risk factor for atherosclerosis in chronic uremic patients. Kidney Int Suppl 1993;41:S72-7.
20. Malinow MR, Rajkovic A, Duell PB, Hess DL, Upson BM. The relationship between maternal and neonatal umbilical cord plasma homocyst(e)ine suggests a potential role for maternal homocyst(e)ine in fetal metabolism. Am J Obstet Gynecol 1998;178:228-33.
21. Sohda S, Arinami T, Hamada H, Vamada N, Hamaguchi H, Kubo T. Methylenetetrahydrofolate reductase polymorphism and preedampsia. J Med Genet 1997;34:525-6.
22. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, et al. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nat Genet 1945;10:111-3.
23. Kang S-S, Wong PWK, Zhou J, Cook HV. Total homocyst(e)ine in plasma and amniotic fluid in pregnant women. Metabolism 1986;35:889-91
24. Andersson A, Hultberg B, Brattström L, Isaksson A. Decreased serum homocysteine in pregnancy. Eur J Clin Chem Clin Biochem 1992;30:377-9.
25. Guttormsen AB, Mansoor AM, Fiskerstrand T, Ueland PM, Refsum H. Kinetics of plasma homocysteine in healthy subjects after peroral homocysteine loading. Clin Chem 1993;39;1390-7.
26. Guttormsen AB, Ueland PM, Svarstad F, Refsum H. Kinetic basis of hyperhomocysteinemia in patients with chronic renal failure. Kidney Int 1997;52:495-502.