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Volumn 88, Issue 1, 2010, Pages 11-22

Antiepileptic drugs and brain development

Author keywords

Anticonvulsants; Apoptosis; Development; Neurodegeneration; Neurogenesis; Synaptogenesis

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE; CARBAMAZEPINE; CLONAZEPAM; DIAZEPAM; ETIRACETAM; GABAPENTIN; HISTONE DEACETYLASE; ISOFLURANE; LAMOTRIGINE; MIDAZOLAM; NITROUS OXIDE; OXAZEPAM; PHENOBARBITAL; PHENYTOIN; TOPIRAMATE; VALPROIC ACID; VIGABATRIN;

EID: 72249097937     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2009.09.019     Document Type: Review
Times cited : (128)

References (112)
  • 2
    • 0027208145 scopus 로고
    • Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors
    • Bashir Z.I., Bortolotto Z.A., Davies C.H., Berretta N., Irving A.J., and Seal A.J. Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors. Nature 363 (1993) 347-350
    • (1993) Nature , vol.363 , pp. 347-350
    • Bashir, Z.I.1    Bortolotto, Z.A.2    Davies, C.H.3    Berretta, N.4    Irving, A.J.5    Seal, A.J.6
  • 3
    • 0027230454 scopus 로고
    • Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat
    • Bayer S.A., Altman J., Russo R.J., and Zhang X. Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat. Neurotoxicology 14 (1993) 83-144
    • (1993) Neurotoxicology , vol.14 , pp. 83-144
    • Bayer, S.A.1    Altman, J.2    Russo, R.J.3    Zhang, X.4
  • 4
    • 0019459136 scopus 로고
    • Adverse effects of phenobarbital on morphological and biochemical development of fetal mouse spinal cord neurons in culture
    • Bergey G.K., Swaiman K.F., Schrier B.K., Fitzgerald S., and Nelson P.G. Adverse effects of phenobarbital on morphological and biochemical development of fetal mouse spinal cord neurons in culture. Ann. Neurol. 9 (1981) 584-589
    • (1981) Ann. Neurol. , vol.9 , pp. 584-589
    • Bergey, G.K.1    Swaiman, K.F.2    Schrier, B.K.3    Fitzgerald, S.4    Nelson, P.G.5
  • 5
    • 0019903796 scopus 로고
    • Neuronal losses in mice following both prenatal and neonatal exposure to phenobarbital
    • Bergman A., Feigenbaum J.J., and Yanai J. Neuronal losses in mice following both prenatal and neonatal exposure to phenobarbital. Acta Anat. 114 (1982) 185-192
    • (1982) Acta Anat. , vol.114 , pp. 185-192
    • Bergman, A.1    Feigenbaum, J.J.2    Yanai, J.3
  • 6
    • 0026716567 scopus 로고
    • Selective changes in mouse behavioural development after prenatal benzodiazepine exposure: a progress resport
    • Bignami G., Alleva E., Chiarotti F., and Laviola G. Selective changes in mouse behavioural development after prenatal benzodiazepine exposure: a progress resport. Prog. Neuropsychopharmacol. Biol. Psychiatry 16 (1992) 587-604
    • (1992) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.16 , pp. 587-604
    • Bignami, G.1    Alleva, E.2    Chiarotti, F.3    Laviola, G.4
  • 8
    • 0020053115 scopus 로고
    • Phenytoin neurotoxicity in developing mouse cerebellum in tissue culture
    • Blank N.K., Nishimura R.N., and Seil F.J. Phenytoin neurotoxicity in developing mouse cerebellum in tissue culture. J. Neurol. Sci. 55 (1982) 91-97
    • (1982) J. Neurol. Sci. , vol.55 , pp. 91-97
    • Blank, N.K.1    Nishimura, R.N.2    Seil, F.J.3
  • 9
    • 0031817683 scopus 로고    scopus 로고
    • Comparison of valproate and phenobarbital treatment after status epilepticus in rats
    • Bolanos A.R., Sarkisian M., Yang Y., Hori A., Helmers S.L., and Mikati M. Comparison of valproate and phenobarbital treatment after status epilepticus in rats. Neurology 51 (1998) 41-48
    • (1998) Neurology , vol.51 , pp. 41-48
    • Bolanos, A.R.1    Sarkisian, M.2    Yang, Y.3    Hori, A.4    Helmers, S.L.5    Mikati, M.6
  • 10
    • 0030975604 scopus 로고    scopus 로고
    • Effect of chronic administration of NMDA antagonists on synaptic development
    • Brooks W.J., Petit T.L., and LeBoutillier J.C. Effect of chronic administration of NMDA antagonists on synaptic development. Synapse 26 (1997) 104-113
    • (1997) Synapse , vol.26 , pp. 104-113
    • Brooks, W.J.1    Petit, T.L.2    LeBoutillier, J.C.3
  • 12
    • 0026713275 scopus 로고
    • Suppression of MAP2 in cultured cerebellar macroneurons inhibits minor neurite formation
    • Caceres A., Mautino J., and Kosik K.S. Suppression of MAP2 in cultured cerebellar macroneurons inhibits minor neurite formation. Neuron 9 (1992) 607-618
    • (1992) Neuron , vol.9 , pp. 607-618
    • Caceres, A.1    Mautino, J.2    Kosik, K.S.3
  • 13
    • 0036775682 scopus 로고    scopus 로고
    • Effect of topiramate following recurrent and prolonged seizures during early development
    • Cha B.H., Silveira D.C., Liu X., Hu Y., and Holmes G.L. Effect of topiramate following recurrent and prolonged seizures during early development. Epilepsy Res. 51 (2002) 217-232
    • (2002) Epilepsy Res. , vol.51 , pp. 217-232
    • Cha, B.H.1    Silveira, D.C.2    Liu, X.3    Hu, Y.4    Holmes, G.L.5
  • 15
    • 0033951606 scopus 로고    scopus 로고
    • The potential for vigabatrin-induced intramyelinic edema in humans
    • Cohen J.A., Fisher R.S., Brigell M.G., Peyster R.G., and Sze G. The potential for vigabatrin-induced intramyelinic edema in humans. Epilepsia 41 (2000) 148-157
    • (2000) Epilepsia , vol.41 , pp. 148-157
    • Cohen, J.A.1    Fisher, R.S.2    Brigell, M.G.3    Peyster, R.G.4    Sze, G.5
  • 16
    • 15244362235 scopus 로고    scopus 로고
    • International Lamotrigine Pregnancy Registry Scientific Advisory Committee. Lamotrigine and the risk of malformations in pregnancy
    • Cunnington M., and Tennis P. International Lamotrigine Pregnancy Registry Scientific Advisory Committee. Lamotrigine and the risk of malformations in pregnancy. Neurology 64 (2005) 955-960
    • (2005) Neurology , vol.64 , pp. 955-960
    • Cunnington, M.1    Tennis, P.2
  • 17
    • 0017803732 scopus 로고
    • Phenobarbital: effects of long-term administration on behavior and brain of artificially reared rats
    • Diaz J., and Schain R.J. Phenobarbital: effects of long-term administration on behavior and brain of artificially reared rats. Science 199 (1978) 90-91
    • (1978) Science , vol.199 , pp. 90-91
    • Diaz, J.1    Schain, R.J.2
  • 18
    • 0000672911 scopus 로고
    • The later development of the brain and its vulnerability
    • Davis J.A., and Dobbing J. (Eds), Saunders, Philadelphia
    • Dobbing J. The later development of the brain and its vulnerability. In: Davis J.A., and Dobbing J. (Eds). Scientific Foundations of Pediatrics (1974), Saunders, Philadelphia 565-577
    • (1974) Scientific Foundations of Pediatrics , pp. 565-577
    • Dobbing, J.1
  • 19
    • 0018372689 scopus 로고
    • Comparative aspects of the brain growth spurt
    • Dobbing J., and Sands J. Comparative aspects of the brain growth spurt. Early Hum. Dev. 3 (1979) 79-83
    • (1979) Early Hum. Dev. , vol.3 , pp. 79-83
    • Dobbing, J.1    Sands, J.2
  • 20
    • 0015886330 scopus 로고
    • The quantitative growth and development of the human brain
    • Dobbing J., and Sands J. The quantitative growth and development of the human brain. Arch. Dis. Child. 48 (1993) 757-767
    • (1993) Arch. Dis. Child. , vol.48 , pp. 757-767
    • Dobbing, J.1    Sands, J.2
  • 21
    • 54049102073 scopus 로고    scopus 로고
    • Does lamotrigine use in pregnancy increase orofacial cleft risk relative to other malformations?
    • on behalf of the EUROCAT Antiepileptic Drug Working Group
    • Dolk, H., Jentink, J., Loane, M., Morris, J., De Jong-van den Berg, L.T.W., on behalf of the EUROCAT Antiepileptic Drug Working Group, 2008. Does lamotrigine use in pregnancy increase orofacial cleft risk relative to other malformations? Neurology 71, 714-722.
    • (2008) Neurology , vol.71 , pp. 714-722
    • Dolk, H.1    Jentink, J.2    Loane, M.3    Morris, J.4    De Jong-van den Berg, L.T.W.5
  • 22
    • 0026714596 scopus 로고
    • Trophic effects of neurotransmitters during brain maturation
    • Emerit M.B., Riad M., and Hamon M. Trophic effects of neurotransmitters during brain maturation. Biol. Neonate 62 (1992) 193-201
    • (1992) Biol. Neonate , vol.62 , pp. 193-201
    • Emerit, M.B.1    Riad, M.2    Hamon, M.3
  • 23
    • 0033968253 scopus 로고    scopus 로고
    • A mouse model for valproate teratogenicity: parental effects, homeotic transformation, and altered HOX expression
    • Faiella A., Wernig M., Consalez G.G., Hostick U., Hoffman C., and Hustert E. A mouse model for valproate teratogenicity: parental effects, homeotic transformation, and altered HOX expression. Hum. Mol. Genet. 9 (2000) 227-236
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 227-236
    • Faiella, A.1    Wernig, M.2    Consalez, G.G.3    Hostick, U.4    Hoffman, C.5    Hustert, E.6
  • 24
    • 0025165146 scopus 로고
    • Changes in seizure threshold and aggression during chronic treatment with three anticonvulsants and on drug withdrawal
    • File S.E., and Wilks L.J. Changes in seizure threshold and aggression during chronic treatment with three anticonvulsants and on drug withdrawal. Psychopharmacology (Berl.) 100 (1990) 237-242
    • (1990) Psychopharmacology (Berl.) , vol.100 , pp. 237-242
    • File, S.E.1    Wilks, L.J.2
  • 26
    • 0020674076 scopus 로고
    • Ultrastructural evidence of long-lasting cerebellar degeneration after early exposure to phenobarbital in mice
    • Fishman R.H.B., Ornoy A., and Yanai J. Ultrastructural evidence of long-lasting cerebellar degeneration after early exposure to phenobarbital in mice. Exp. Neurol. 79 (1983) 212-220
    • (1983) Exp. Neurol. , vol.79 , pp. 212-220
    • Fishman, R.H.B.1    Ornoy, A.2    Yanai, J.3
  • 27
    • 0024590990 scopus 로고
    • Correlated ultrastructural damage between cerebellum cells after early anticonvulsant treatment in mice
    • Fishman R.H., Ornoy A., and Yanai J. Correlated ultrastructural damage between cerebellum cells after early anticonvulsant treatment in mice. Int. J. Dev. Neurosci. 7 (1989) 15-26
    • (1989) Int. J. Dev. Neurosci. , vol.7 , pp. 15-26
    • Fishman, R.H.1    Ornoy, A.2    Yanai, J.3
  • 29
    • 18244383806 scopus 로고    scopus 로고
    • Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
    • Gottlicher M., Minucci S., Zhu P., Kramer O.H., Schimpf A., and Giavara S. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 29 (2001) 6969-6978
    • (2001) EMBO J. , vol.29 , pp. 6969-6978
    • Gottlicher, M.1    Minucci, S.2    Zhu, P.3    Kramer, O.H.4    Schimpf, A.5    Giavara, S.6
  • 31
    • 0037301661 scopus 로고    scopus 로고
    • The Yin and Yang of NMDA receptor signalling
    • Hardingham G.E., and Bading H. The Yin and Yang of NMDA receptor signalling. Trends Neurosci. 26 (2003) 81-89
    • (2003) Trends Neurosci. , vol.26 , pp. 81-89
    • Hardingham, G.E.1    Bading, H.2
  • 32
    • 0032969701 scopus 로고    scopus 로고
    • Neurotoxic effects of phenytoin on postnatal mouse brain development following neonatal administration
    • Hatta T., Ohmori H., Murakami T., Takano M., Yamashita K., and Yasuda M. Neurotoxic effects of phenytoin on postnatal mouse brain development following neonatal administration. Neurotoxicol. Teratol. 21 (1999) 21-28
    • (1999) Neurotoxicol. Teratol. , vol.21 , pp. 21-28
    • Hatta, T.1    Ohmori, H.2    Murakami, T.3    Takano, M.4    Yamashita, K.5    Yasuda, M.6
  • 33
    • 0027979943 scopus 로고
    • The prevalence and incidence of convulsive disorders in children
    • Hauser W.A. The prevalence and incidence of convulsive disorders in children. Epilepsia 35 Suppl. 2 (1994) S1-6
    • (1994) Epilepsia , vol.35 , Issue.SUPPL. 2
    • Hauser, W.A.1
  • 34
    • 0030273542 scopus 로고    scopus 로고
    • Programmed cell death in the developing nervous system
    • Henderson C.E. Programmed cell death in the developing nervous system. Neuron 17 (1996) 579-585
    • (1996) Neuron , vol.17 , pp. 579-585
    • Henderson, C.E.1
  • 36
    • 0029002241 scopus 로고
    • Dissociation between the attentional effects of infusions of a benzodiazepine receptor agonist and an inverse agonist into the basal forebrain
    • Holley L.A., Turchi J., Apple C., and Sarter M. Dissociation between the attentional effects of infusions of a benzodiazepine receptor agonist and an inverse agonist into the basal forebrain. Psychopharmacology (Berl.) 120 (1995) 99-108
    • (1995) Psychopharmacology (Berl.) , vol.120 , pp. 99-108
    • Holley, L.A.1    Turchi, J.2    Apple, C.3    Sarter, M.4
  • 38
    • 33745959285 scopus 로고    scopus 로고
    • Increased risk for non-syndromic cleft palate among infants exposed to lamotrigine during pregnancy
    • Holmes L.B., Wyszynski D.F., Baldwin E.J., et al. Increased risk for non-syndromic cleft palate among infants exposed to lamotrigine during pregnancy. Birth Def. Res. (Part A): Clin. Mol. Teratol. 76 (2006) 318
    • (2006) Birth Def. Res. (Part A): Clin. Mol. Teratol. , vol.76 , pp. 318
    • Holmes, L.B.1    Wyszynski, D.F.2    Baldwin, E.J.3
  • 43
    • 0034612151 scopus 로고    scopus 로고
    • Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism
    • Ingram J.L., Peckham S.M., Tisdale B., and Rodier P.M. Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism. Neurotoxicol. Teratol. 22 (2000) 319-324
    • (2000) Neurotoxicol. Teratol. , vol.22 , pp. 319-324
    • Ingram, J.L.1    Peckham, S.M.2    Tisdale, B.3    Rodier, P.M.4
  • 45
    • 0029164633 scopus 로고
    • NBQX blocks acute and late epileptogenic effects of perinatal hypoxia
    • Jensen F.E., Blume H., Alvarado S., Firkusny I., and Geary C. NBQX blocks acute and late epileptogenic effects of perinatal hypoxia. Epilepsia 36 (1995) 966-972
    • (1995) Epilepsia , vol.36 , pp. 966-972
    • Jensen, F.E.1    Blume, H.2    Alvarado, S.3    Firkusny, I.4    Geary, C.5
  • 46
    • 0037321378 scopus 로고    scopus 로고
    • Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits
    • Jevtovic-Todorovic V., Hartman R.E., Izumi Y., Benshoff N.D., Dikranian K., and Zorumski C.F. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J. Neurosci. 23 (2003) 876-882
    • (2003) J. Neurosci. , vol.23 , pp. 876-882
    • Jevtovic-Todorovic, V.1    Hartman, R.E.2    Izumi, Y.3    Benshoff, N.D.4    Dikranian, K.5    Zorumski, C.F.6
  • 47
    • 0027396983 scopus 로고
    • Molecular mechanisms of developmental neuronal death
    • Johnson E.M., and Deckwerth T.L. Molecular mechanisms of developmental neuronal death. Annu. Rev. Neurosci. 16 (1993) 31-46
    • (1993) Annu. Rev. Neurosci. , vol.16 , pp. 31-46
    • Johnson, E.M.1    Deckwerth, T.L.2
  • 48
    • 0024399184 scopus 로고
    • Pattern of malformations in the children of women treated with carbamazepine during pregnancy
    • Jones K.L., Lacro R.V., Johnson K.A., and Adams J. Pattern of malformations in the children of women treated with carbamazepine during pregnancy. N. Engl. J. Med. 320 (1989) 1661-1666
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1661-1666
    • Jones, K.L.1    Lacro, R.V.2    Johnson, K.A.3    Adams, J.4
  • 50
    • 34547124067 scopus 로고    scopus 로고
    • Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain
    • Katz I., Kim J., Gale K.N., and Kondratyev A.D. Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain. J. Pharmacol. Exp. Ther. 322 (2007) 494-500
    • (2007) J. Pharmacol. Exp. Ther. , vol.322 , pp. 494-500
    • Katz, I.1    Kim, J.2    Gale, K.N.3    Kondratyev, A.D.4
  • 51
    • 0032760694 scopus 로고    scopus 로고
    • Sex differences in long-term consequences of prenatal diazepam exposure: possible underlying mechanisms
    • Kellogg C.K. Sex differences in long-term consequences of prenatal diazepam exposure: possible underlying mechanisms. Pharmacol. Biochem. Behav. 64 (1999) 673-680
    • (1999) Pharmacol. Biochem. Behav. , vol.64 , pp. 673-680
    • Kellogg, C.K.1
  • 52
    • 0029125107 scopus 로고
    • Phenytoin inhibits expression of microtubule-associated protein 2 and influences cell-viability and neurite growth of cultured cerebellar granule cells
    • Kempermann G., and Volk B. Phenytoin inhibits expression of microtubule-associated protein 2 and influences cell-viability and neurite growth of cultured cerebellar granule cells. Brain Res. 687 (1995) 194-198
    • (1995) Brain Res. , vol.687 , pp. 194-198
    • Kempermann, G.1    Volk, B.2
  • 53
    • 34548851761 scopus 로고    scopus 로고
    • Antiepileptic drug-induced neuronal cell death in the immature brain: effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy
    • Kim J., Kondratyev A., and Gale K. Antiepileptic drug-induced neuronal cell death in the immature brain: effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy. J. Pharmacol. Exp. Ther. 323 (2007) 165-173
    • (2007) J. Pharmacol. Exp. Ther. , vol.323 , pp. 165-173
    • Kim, J.1    Kondratyev, A.2    Gale, K.3
  • 54
    • 0034854281 scopus 로고    scopus 로고
    • Topiramate blocks perinatal hypoxia-induced seizures in rat pups
    • Koh S., and Jensen F.E. Topiramate blocks perinatal hypoxia-induced seizures in rat pups. Ann. Neurol. 50 (2001) 366-372
    • (2001) Ann. Neurol. , vol.50 , pp. 366-372
    • Koh, S.1    Jensen, F.E.2
  • 55
    • 0019903829 scopus 로고
    • Effects of phenytoin on schedule-controlled performance of rats
    • Krafft K., Lyon D.O., and Poling A. Effects of phenytoin on schedule-controlled performance of rats. Psychopharmacology 78 (1982) 93-95
    • (1982) Psychopharmacology , vol.78 , pp. 93-95
    • Krafft, K.1    Lyon, D.O.2    Poling, A.3
  • 56
    • 4744346077 scopus 로고    scopus 로고
    • The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells
    • Laeng P., Pitts R.L., Lemire A.L., Drabik C.E., Weiner A., and Tang H. The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells. J. Neurochem. 91 (2004) 238-251
    • (2004) J. Neurochem. , vol.91 , pp. 238-251
    • Laeng, P.1    Pitts, R.L.2    Lemire, A.L.3    Drabik, C.E.4    Weiner, A.5    Tang, H.6
  • 58
    • 0035707110 scopus 로고    scopus 로고
    • NMDA receptor activation limits the number of synaptic connections during hippocampal development
    • Luthi A., Schwyzer L., Mateos J.M., Gähwiler B.H., and McKinney R.A. NMDA receptor activation limits the number of synaptic connections during hippocampal development. Nat. Neurosci. 4 (2001) 1102-1107
    • (2001) Nat. Neurosci. , vol.4 , pp. 1102-1107
    • Luthi, A.1    Schwyzer, L.2    Mateos, J.M.3    Gähwiler, B.H.4    McKinney, R.A.5
  • 59
    • 34247145936 scopus 로고    scopus 로고
    • Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias
    • Manent J.B., Jorquera I., Mazzucchelli I., et al. Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias. Epilepsia 48 (2007) 684-693
    • (2007) Epilepsia , vol.48 , pp. 684-693
    • Manent, J.B.1    Jorquera, I.2    Mazzucchelli, I.3
  • 61
    • 33845625723 scopus 로고    scopus 로고
    • Seizures and antiepileptic drugs: does exposure alter normal brain development?
    • Marsh E.D., Brooks-Kayal A.R., and Ported B.E. Seizures and antiepileptic drugs: does exposure alter normal brain development?. Epilepsia 47 (2006) 1999-2010
    • (2006) Epilepsia , vol.47 , pp. 1999-2010
    • Marsh, E.D.1    Brooks-Kayal, A.R.2    Ported, B.E.3
  • 62
    • 0025768290 scopus 로고
    • The anticonvulsant valproate teratogen restricts the glial cell cycle at a defined point in the mid G1 phase
    • Martin M.L., and Regan C.M. The anticonvulsant valproate teratogen restricts the glial cell cycle at a defined point in the mid G1 phase. Brain Res. 554 (1991) 223-228
    • (1991) Brain Res. , vol.554 , pp. 223-228
    • Martin, M.L.1    Regan, C.M.2
  • 63
    • 33746079194 scopus 로고    scopus 로고
    • In untero antiepileptic drug exposure. Fetal death and malformations
    • Meador K.J., Baker G.A., and Finnelli R.H. In untero antiepileptic drug exposure. Fetal death and malformations. Neurology 67 (2006) 407-412
    • (2006) Neurology , vol.67 , pp. 407-412
    • Meador, K.J.1    Baker, G.A.2    Finnelli, R.H.3
  • 67
    • 0022243047 scopus 로고
    • Differential toxicity of chronic exposure to phenytoin, phenobarbital or carbamazepine in cerebral cortical cell cultures
    • Neale E.A., Sher P.K., Granbard B.I., Habig M., Fitzgerald S.C., and Nelson P.G. Differential toxicity of chronic exposure to phenytoin, phenobarbital or carbamazepine in cerebral cortical cell cultures. Pediatr. Neurol. 1 (1985) 143-150
    • (1985) Pediatr. Neurol. , vol.1 , pp. 143-150
    • Neale, E.A.1    Sher, P.K.2    Granbard, B.I.3    Habig, M.4    Fitzgerald, S.C.5    Nelson, P.G.6
  • 69
    • 45849123499 scopus 로고    scopus 로고
    • Neurodevelopmental delay in children exposed to antiepileptic drugs in utero: a critical review directed at structural study-bias
    • Nicolai J., Vles J.S.H., and Aldenkamp A.P. Neurodevelopmental delay in children exposed to antiepileptic drugs in utero: a critical review directed at structural study-bias. J. Neurol. Sci. 271 (2008) 1-14
    • (2008) J. Neurol. Sci. , vol.271 , pp. 1-14
    • Nicolai, J.1    Vles, J.S.H.2    Aldenkamp, A.P.3
  • 70
    • 0036841249 scopus 로고    scopus 로고
    • Neurotoxic damage of granule cells in the dentate gyrus and the cerebellum and cognitive deficit following neonatal administration of phenytoin in mice
    • Ogura H., Yasuda M., Nakamura S., Yamashita H., Mikoshiba K., and Ohmori H. Neurotoxic damage of granule cells in the dentate gyrus and the cerebellum and cognitive deficit following neonatal administration of phenytoin in mice. J. Neuropathol. Exp. Neurol. 61 (2002) 956-967
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 956-967
    • Ogura, H.1    Yasuda, M.2    Nakamura, S.3    Yamashita, H.4    Mikoshiba, K.5    Ohmori, H.6
  • 72
    • 0032994491 scopus 로고    scopus 로고
    • Developmental neurotoxicity of phenytoin on granule cells and Purkinje cells in mouse cerebellum
    • Ohmori H., Ogura H., Yasuda M., Nakamura S., Hatta T., and Kawano K. Developmental neurotoxicity of phenytoin on granule cells and Purkinje cells in mouse cerebellum. J. Neurochem. 72 (1999) 1497-1506
    • (1999) J. Neurochem. , vol.72 , pp. 1497-1506
    • Ohmori, H.1    Ogura, H.2    Yasuda, M.3    Nakamura, S.4    Hatta, T.5    Kawano, K.6
  • 74
    • 0022407050 scopus 로고
    • Rates of brain development in mammals including man
    • Passingham R.E. Rates of brain development in mammals including man. Brain Behav. Evol. 26 (1985) 167-175
    • (1985) Brain Behav. Evol. , vol.26 , pp. 167-175
    • Passingham, R.E.1
  • 75
    • 0020414953 scopus 로고
    • Brain maturation following administration of phenobarbital, phenytoin, and sodium valproate to developing rats or to their dams: effects on synthesis of brain myelin and other subcellular membrane proteins
    • Patsalos P.N., and Wiggins R.C. Brain maturation following administration of phenobarbital, phenytoin, and sodium valproate to developing rats or to their dams: effects on synthesis of brain myelin and other subcellular membrane proteins. J. Neurochem. 39 (1982) 915-923
    • (1982) J. Neurochem. , vol.39 , pp. 915-923
    • Patsalos, P.N.1    Wiggins, R.C.2
  • 77
    • 0023156349 scopus 로고
    • Effects of diazepam on cell proliferation in cerebral cortex, anterior pituitary and thymus of developing rats
    • Pawlikowski M., Ste{ogonek}pien H., Mróz-Wasilewska Z., and Pawlikowska A. Effects of diazepam on cell proliferation in cerebral cortex, anterior pituitary and thymus of developing rats. Life Sci. 40 (1987) 1131-1135
    • (1987) Life Sci. , vol.40 , pp. 1131-1135
    • Pawlikowski, M.1    Stepien, H.2    Mróz-Wasilewska, Z.3    Pawlikowska, A.4
  • 78
    • 0024550594 scopus 로고
    • Inhibition by diazepam of the effect of additional training and of extinction on the retention of shuttle avoidance behavior in rats
    • Pereira M.E., Rosat R., Huang C.H., Godoy M.G., and Izquierdo I. Inhibition by diazepam of the effect of additional training and of extinction on the retention of shuttle avoidance behavior in rats. Behav. Neurosci. 103 (1989) 202-205
    • (1989) Behav. Neurosci. , vol.103 , pp. 202-205
    • Pereira, M.E.1    Rosat, R.2    Huang, C.H.3    Godoy, M.G.4    Izquierdo, I.5
  • 79
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer and teratogen
    • Phiel C.J., Zhang F., Huang E.Y., Guenther M.G., Lazar M.A., and Klein P.S. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer and teratogen. J. Biol. Chem. 276 (2001) 26724-26731
    • (2001) J. Biol. Chem. , vol.276 , pp. 26724-26731
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 80
    • 0029788682 scopus 로고    scopus 로고
    • Infant monkey hyperexcitability after prenatal exposure to antiepileptic compounds
    • Phillips N.K., and Lockard J.S. Infant monkey hyperexcitability after prenatal exposure to antiepileptic compounds. Epilepsia 37 (1996) 991-999
    • (1996) Epilepsia , vol.37 , pp. 991-999
    • Phillips, N.K.1    Lockard, J.S.2
  • 81
    • 0021988624 scopus 로고
    • Long-term reduction in eight arm maze performance after early exposure to phenobarbital
    • Pick C.G., and Yanai J. Long-term reduction in eight arm maze performance after early exposure to phenobarbital. Int. J. Dev. Neurosci. 3 (1985) 223-227
    • (1985) Int. J. Dev. Neurosci. , vol.3 , pp. 223-227
    • Pick, C.G.1    Yanai, J.2
  • 82
    • 0021983983 scopus 로고
    • Effects of phenytoin, phenobarbital, and valproic acid, alone and in selected combinations, on schedule-controlled behavior of rats
    • Picker M., Thomas J., Koch C., and Poling A. Effects of phenytoin, phenobarbital, and valproic acid, alone and in selected combinations, on schedule-controlled behavior of rats. Pharmacol. Biochem. Behav. 22 (1985) 389-393
    • (1985) Pharmacol. Biochem. Behav. , vol.22 , pp. 389-393
    • Picker, M.1    Thomas, J.2    Koch, C.3    Poling, A.4
  • 84
    • 0024513746 scopus 로고
    • Effects of phenytoin and phenobarbital on schedule-controlled responding and seizure activity in the amygdala-kindled rat
    • Renfrey G., Schlinger H., Jakubow J., and Poling A. Effects of phenytoin and phenobarbital on schedule-controlled responding and seizure activity in the amygdala-kindled rat. J. Pharmacol. Exp. Ther. 248 (1989) 967-973
    • (1989) J. Pharmacol. Exp. Ther. , vol.248 , pp. 967-973
    • Renfrey, G.1    Schlinger, H.2    Jakubow, J.3    Poling, A.4
  • 85
    • 0029925646 scopus 로고    scopus 로고
    • Neurotransmission and the ontogeny of human brain
    • Retz W., Kornhuber J., and Riederer P. Neurotransmission and the ontogeny of human brain. J. Neural Transm. 103 (1996) 403-419
    • (1996) J. Neural Transm. , vol.103 , pp. 403-419
    • Retz, W.1    Kornhuber, J.2    Riederer, P.3
  • 86
    • 0033911258 scopus 로고    scopus 로고
    • Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models
    • Rice D., and Barone S. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ. Health Perspect. 208 (2000) 511-533
    • (2000) Environ. Health Perspect. , vol.208 , pp. 511-533
    • Rice, D.1    Barone, S.2
  • 87
    • 0018951060 scopus 로고
    • Chronology of neuron development: animal studies and their clinical implications
    • Rodier P.M. Chronology of neuron development: animal studies and their clinical implications. Dev. Med. Child Neurol. 22 (1980) 525-545
    • (1980) Dev. Med. Child Neurol. , vol.22 , pp. 525-545
    • Rodier, P.M.1
  • 88
    • 0028291958 scopus 로고
    • Vulnerable periods and processes during central nervous system development
    • Rodier P.M. Vulnerable periods and processes during central nervous system development. Environ. Health Perspect. 102 Suppl. 2 (1994) 121-124
    • (1994) Environ. Health Perspect. , vol.102 , Issue.SUPPL. 2 , pp. 121-124
    • Rodier, P.M.1
  • 89
    • 0028786105 scopus 로고
    • Developing brain as a target of toxicity
    • Rodier P.M. Developing brain as a target of toxicity. Environ. Health Perspect. 103 Suppl. 6 (1995) 73-76
    • (1995) Environ. Health Perspect. , vol.103 , Issue.SUPPL. 6 , pp. 73-76
    • Rodier, P.M.1
  • 90
    • 3042798891 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs
    • Rogawski M.A., and Löscher W. The neurobiology of antiepileptic drugs. Nat. Rev. Neurosci. 5 (2004) 553-564
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 553-564
    • Rogawski, M.A.1    Löscher, W.2
  • 91
    • 0026717484 scopus 로고
    • Hippocampal cholinergic alterations and related behavioral deficits after early exposure to phenobarbital
    • Roger-Fuchs Y., Newman M.E., Trombka D., Zabalke E., and Yanai J. Hippocampal cholinergic alterations and related behavioral deficits after early exposure to phenobarbital. Brain Res. Bull. 29 (1992) 1-6
    • (1992) Brain Res. Bull. , vol.29 , pp. 1-6
    • Roger-Fuchs, Y.1    Newman, M.E.2    Trombka, D.3    Zabalke, E.4    Yanai, J.5
  • 92
    • 0024423369 scopus 로고
    • Effects of carbamazepine, valproate calcium, clonazepam and piracetam on behavioral test methods for evaluation of memory-enhancing drugs
    • Rostock A., Hoffmann W., Siegemund C., and Bartsch R. Effects of carbamazepine, valproate calcium, clonazepam and piracetam on behavioral test methods for evaluation of memory-enhancing drugs. Methods Find Exp. Clin. Pharmacol. 11 (1989) 547-553
    • (1989) Methods Find Exp. Clin. Pharmacol. , vol.11 , pp. 547-553
    • Rostock, A.1    Hoffmann, W.2    Siegemund, C.3    Bartsch, R.4
  • 93
    • 0033199594 scopus 로고    scopus 로고
    • Prenatal phenytoin exposure and spatial navigation in offspring: effects on reference and working memory and on discrimination learning
    • Schilling M.A., Inman S.L., Morford L.L., Moran M.S., and Vorhees C.V. Prenatal phenytoin exposure and spatial navigation in offspring: effects on reference and working memory and on discrimination learning. Neurotoxicol. Teratol. 21 (1999) 567-578
    • (1999) Neurotoxicol. Teratol. , vol.21 , pp. 567-578
    • Schilling, M.A.1    Inman, S.L.2    Morford, L.L.3    Moran, M.S.4    Vorhees, C.V.5
  • 94
    • 0023733767 scopus 로고
    • Effects of chronic phenobarbital exposure on cultured mouse spinal cord neurons
    • Serrano E.E., Kunis D.M., and Ransom B.R. Effects of chronic phenobarbital exposure on cultured mouse spinal cord neurons. Ann. Neurol. 24 (1988) 429-438
    • (1988) Ann. Neurol. , vol.24 , pp. 429-438
    • Serrano, E.E.1    Kunis, D.M.2    Ransom, B.R.3
  • 95
    • 34250715419 scopus 로고    scopus 로고
    • Teratogenicity of lamotrigine
    • Shor S., Koren G., and Nulman I. Teratogenicity of lamotrigine. Can. Fam. Phys. 53 (2007) 1007-1009
    • (2007) Can. Fam. Phys. , vol.53 , pp. 1007-1009
    • Shor, S.1    Koren, G.2    Nulman, I.3
  • 96
    • 0031128129 scopus 로고    scopus 로고
    • Low-dose vigabatrin (gamma-vinyl GABA)-induced damage in the immature rat brain
    • Sidhu R.S., Del Bigio M.R., Tuor U.I., and Seshia S.S. Low-dose vigabatrin (gamma-vinyl GABA)-induced damage in the immature rat brain. Exp. Neurol. 144 (1997) 400-405
    • (1997) Exp. Neurol. , vol.144 , pp. 400-405
    • Sidhu, R.S.1    Del Bigio, M.R.2    Tuor, U.I.3    Seshia, S.S.4
  • 97
    • 0020584563 scopus 로고
    • Lithium and carbamazepine: effects on learned taste aversion and open field behavior in rats
    • Smith D.F. Lithium and carbamazepine: effects on learned taste aversion and open field behavior in rats. Pharmacol. Biochem. Behav. 18 (1983) 483-488
    • (1983) Pharmacol. Biochem. Behav. , vol.18 , pp. 483-488
    • Smith, D.F.1
  • 98
    • 0015518918 scopus 로고
    • Maternal epilepsy and abnormalities of the fetus and newborn
    • Speidel B.D., and Meador S.R. Maternal epilepsy and abnormalities of the fetus and newborn. Lancet 308 (1972) 839-843
    • (1972) Lancet , vol.308 , pp. 839-843
    • Speidel, B.D.1    Meador, S.R.2
  • 101
    • 38349059230 scopus 로고    scopus 로고
    • Prenatal and family risks of children born to mothers with epilepsy: effects on cognitive development
    • Titze K., Koch S., Helge H., Lehmkuhl U., Rauh H., and Steinhausen H.-C. Prenatal and family risks of children born to mothers with epilepsy: effects on cognitive development. Dev. Med. Child Neurol. 50 (2008) 117-122
    • (2008) Dev. Med. Child Neurol. , vol.50 , pp. 117-122
    • Titze, K.1    Koch, S.2    Helge, H.3    Lehmkuhl, U.4    Rauh, H.5    Steinhausen, H.-C.6
  • 102
    • 0034496485 scopus 로고    scopus 로고
    • The replacement of oestradiol and progesterone in very premature infants
    • Trotter A., and Pohlandt F. The replacement of oestradiol and progesterone in very premature infants. Ann. Med. 32 (2000) 608-614
    • (2000) Ann. Med. , vol.32 , pp. 608-614
    • Trotter, A.1    Pohlandt, F.2
  • 103
    • 15244345581 scopus 로고    scopus 로고
    • Neuropsychological effects of exposure to anticonvulsant medication in utero
    • Vinten J., Adab N., and Kini U. Neuropsychological effects of exposure to anticonvulsant medication in utero. Neurology 64 (2005) 949-954
    • (2005) Neurology , vol.64 , pp. 949-954
    • Vinten, J.1    Adab, N.2    Kini, U.3
  • 104
    • 0023190512 scopus 로고
    • Fetal hydanthoin syndrome in rats: dose-effect relationships of prenatal phenytoin on postnatal development and behavior
    • Vorhees C.V. Fetal hydanthoin syndrome in rats: dose-effect relationships of prenatal phenytoin on postnatal development and behavior. Teratology 35 (1987) 287-303
    • (1987) Teratology , vol.35 , pp. 287-303
    • Vorhees, C.V.1
  • 105
    • 0023257580 scopus 로고
    • Behavioral teratogenicity of valproic acid: selective effects on behavior after prenatal exposure to rats
    • Vorhees C.V. Behavioral teratogenicity of valproic acid: selective effects on behavior after prenatal exposure to rats. Psychopharmacology 92 (1987) 173-179
    • (1987) Psychopharmacology , vol.92 , pp. 173-179
    • Vorhees, C.V.1
  • 106
    • 0024342729 scopus 로고
    • Long-term effects of prenatal phenytoin exposure on offspring behavior in rats
    • Vorhees C.V., and Minck D.R. Long-term effects of prenatal phenytoin exposure on offspring behavior in rats. Neurotoxicol. Teratol. 11 (1989) 295-305
    • (1989) Neurotoxicol. Teratol. , vol.11 , pp. 295-305
    • Vorhees, C.V.1    Minck, D.R.2
  • 108
    • 0034855192 scopus 로고    scopus 로고
    • Mechanisms of postnatal neurobiological development: implications for human development
    • Webb S.J., Monk C.S., and Nelson C.A. Mechanisms of postnatal neurobiological development: implications for human development. Dev. Neurophychol. 19 (2001) 147-172
    • (2001) Dev. Neurophychol. , vol.19 , pp. 147-172
    • Webb, S.J.1    Monk, C.S.2    Nelson, C.A.3
  • 109
    • 0035088606 scopus 로고    scopus 로고
    • Changing specificity of neurotransmitter regulation of rapid dendritic remodeling during synaptogenesis
    • Wong W.T., and Wong R.O. Changing specificity of neurotransmitter regulation of rapid dendritic remodeling during synaptogenesis. Nat. Neurosci. 4 (2001) 351-352
    • (2001) Nat. Neurosci. , vol.4 , pp. 351-352
    • Wong, W.T.1    Wong, R.O.2
  • 110
    • 0029059598 scopus 로고
    • Diphenylhydanthoin induces apoptotic cell death of culture rat cerebellar granule neurons
    • Yan G.M., Irwin R.P., Liu S.Z., Weller M., Wood K.A., and Paul S.M. Diphenylhydanthoin induces apoptotic cell death of culture rat cerebellar granule neurons. J. Pharmacol. Exp. Ther. 274 (1995) 983-990
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 983-990
    • Yan, G.M.1    Irwin, R.P.2    Liu, S.Z.3    Weller, M.4    Wood, K.A.5    Paul, S.M.6
  • 112
    • 0032254333 scopus 로고    scopus 로고
    • Neurologic care of pregnant women with epilepsy
    • Zahn C.A. Neurologic care of pregnant women with epilepsy. Epilepsia 39 Suppl. 8 (1998) S26-31
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 8
    • Zahn, C.A.1


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