TNF-α inhibits BMP-induced osteoblast differentiation through activating SAPK/JNK signaling

Biochemical and Biophysical Research Communications

Volumn 356, Issue 4, 2007, Pages 1004-1010

  Mukai, Tomoyuki ^a   Otsuka, Fumio ^a   Otani, Hiroyuki ^a   Yamashita, Misuzu ^a   Takasugi, Koji ^a   Inagaki, Kenichi ^a   Yamamura, Masahiro ^b   Makino, Hirofumi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone morphogenetic protein (BMP); C2C12; Mitogen activated protein (MAP) kinase; Osteoblast; Tumor necrosis factor (TNF)

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALK6 PROTEIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN RECEPTOR; COMPLEMENTARY DNA; GENE PRODUCT; INHIBITOR OF DIFFERENTIATION 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OSTEOCALCIN; OSTEOGENIC PROTEIN 1; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD6 PROTEIN; SMAD8 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA DETERMINATION; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; GENE REPRESSION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; MAP KINASE SIGNALING SYSTEM; MICE; MYOBLASTS; OSTEOBLASTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34047152284     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.03.099     Document Type: Article

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