Induction and suppression of an autoimmune disease by oligomerized t cell epitopes: Enhanced in vivo potency of encephalitogenic peptides

Journal of Experimental Medicine

Volumn 191, Issue 4, 2000, Pages 717-730

  Falk, Kirsten ^a   Rötzschke, Olaf ^a   Santambrogio, Laura ^b   Dorf, Martin E ^c   Brosnan, Celia ^d   Strominger, Jack L ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Anergy; Apoptosis; Experimental autoimmune encephalomyelitis; High zone tolerance; Multimer

Indexed keywords

ENCEPHALITOGENIC PROTEIN; EPITOPE; FREUND ADJUVANT; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CLONAL ANERGY; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RELAPSE;

ANIMALS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EPITOPES; FREUND'S ADJUVANT; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED AKR; MICE, INBRED BALB C; MICE, INBRED STRAINS; MYELIN BASIC PROTEINS; MYELIN PROTEOLIPID PROTEIN; SPECIES SPECIFICITY; T-LYMPHOCYTES; TIME FACTORS;

EID: 0034695877     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.4.717     Document Type: Article

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