-
1
-
-
0026531884
-
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques
-
Arnold D. L., Matthews P. M., Francis G. S., O'Connor J. and Antel J. P. (1992) Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques. Ann. Neurol. 31, 235-241.
-
(1992)
Ann. Neurol.
, vol.31
, pp. 235-241
-
-
Arnold, D.L.1
Matthews, P.M.2
Francis, G.S.3
O'Connor, J.4
Antel, J.P.5
-
2
-
-
24744468983
-
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation
-
Back S. A., Tuohy T. M., Chen H., Wallingford N., Craig A., Struve J., Luo N. L., Banine F., Liu Y., Chang A., Trapp B. D., Bebo B. F. Jr, Rao M. S. and Sherman L. S. (2005) Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med. 11, 966-972.
-
(2005)
Nat Med.
, vol.11
, pp. 966-972
-
-
Back, S.A.1
Tuohy, T.M.2
Chen, H.3
Wallingford, N.4
Craig, A.5
Struve, J.6
Luo, N.L.7
Banine, F.8
Liu, Y.9
Chang, A.10
Trapp, B.D.11
Bebo Jr., B.F.12
Rao, M.S.13
Sherman, L.S.14
-
3
-
-
0041522756
-
Remyelinated lesions in multiple sclerosis: Magnetic resonance image appearance
-
Barkhof F., Bruck W., De Groot C. J., Bergers E., Hulshof S., Geurts J., van Polman C. H. and d V. (2003) Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance. Arch. Neurol. 60, 1073-1081.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 1073-1081
-
-
Barkhof, F.1
Bruck, W.2
De Groot, C.J.3
Bergers, E.4
Hulshof, S.5
Geurts, J.6
Van Polman, C.H.7
Van der Valk, P.8
-
4
-
-
27444444869
-
The pathology of multiple sclerosis is the result of focal inflammatory demyelination with axonal damage
-
Bruck W. (2005) The pathology of multiple sclerosis is the result of focal inflammatory demyelination with axonal damage. J. Neurol. 252, v3-v9.
-
(2005)
J. Neurol.
, vol.252
-
-
Bruck, W.1
-
5
-
-
0034660502
-
Regulation of encephalitogenic T cells with recombinant TCR ligands
-
Burrows G. G., Adlard K. L., Bebo B. F. Jr, Chang J. W., Tenditnyy K., Vandenbark A. A. and Offner H. (2000) Regulation of encephalitogenic T cells with recombinant TCR ligands. J. Immunol. 164, 6366-6371.
-
(2000)
J. Immunol.
, vol.164
, pp. 6366-6371
-
-
Burrows, G.G.1
Adlard, K.L.2
Bebo Jr., B.F.3
Chang, J.W.4
Tenditnyy, K.5
Vandenbark, A.A.6
Offner, H.7
-
6
-
-
0035887638
-
Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells
-
Burrows G. G., Chou Y. K., Wang C., Chang J. W., Finn T. P., Culbertson N. E., Kim J., Bourdette D. N., Lewinsohn D. A., Lewinsohn D. M., Ikeda M., Yoshioka T., Allen C. N., Offner H. and Vandenbark A. A. (2001) Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells. J. Immunol. 167, 4386-4395.
-
(2001)
J. Immunol.
, vol.167
, pp. 4386-4395
-
-
Burrows, G.G.1
Chou, Y.K.2
Wang, C.3
Chang, J.W.4
Finn, T.P.5
Culbertson, N.E.6
Kim, J.7
Bourdette, D.N.8
Lewinsohn, D.A.9
Lewinsohn, D.M.10
Ikeda, M.11
Yoshioka, T.12
Allen, C.N.13
Offner, H.14
Vandenbark, A.A.15
-
7
-
-
0035968255
-
Design, engineering, and production of human recombinant T cell receptor ligands derived from human leukocyte antigen DR2
-
Chang J. W., Mechling D. E., Bachinger H. P. and Burrows G. G. (2001) Design, engineering, and production of human recombinant T cell receptor ligands derived from human leukocyte antigen DR2. J. Biol. Chem. 276, 24 170-24 176.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24170-24176
-
-
Chang, J.W.1
Mechling, D.E.2
Bachinger, H.P.3
Burrows, G.G.4
-
8
-
-
0028838289
-
Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury
-
D'Souza S., Alinauskas K., McCrea E., Goodyer C. and Antel J. P. (1995) Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury. J. Neurosci. 15, 7293-7300.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7293-7300
-
-
D'Souza, S.1
Alinauskas, K.2
McCrea, E.3
Goodyer, C.4
Antel, J.P.5
-
9
-
-
18544374335
-
Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study
-
Fassas A., Passweg J. R., Anagnostopoulos A et al. (2002) Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study. J. Neurol. 249, 1088-1097.
-
(2002)
J. Neurol.
, vol.249
, pp. 1088-1097
-
-
Fassas, A.1
Passweg, J.R.2
Anagnostopoulos, A.3
-
10
-
-
0031002545
-
Axonal damage in acute multiple sclerosis lesions
-
Ferguson B., Matyszak M. K., Esiri M. M. and Perry V. H. (1997) Axonal damage in acute multiple sclerosis lesions. Brain 120, 393-399.
-
(1997)
Brain
, vol.120
, pp. 393-399
-
-
Ferguson, B.1
Matyszak, M.K.2
Esiri, M.M.3
Perry, V.H.4
-
11
-
-
0031962941
-
Imaging axonal damage of normal-appearing white matter in multiple sclerosis
-
Fu L., Matthews P. M., De Stefano N., Worsley K. J., Narayanan S., Francis G. S., Antel J. P., Wolfson C. and Arnold D. L. (1998) Imaging axonal damage of normal-appearing white matter in multiple sclerosis. Brain 121, 103-113.
-
(1998)
Brain
, vol.121
, pp. 103-113
-
-
Fu, L.1
Matthews, P.M.2
De Stefano, N.3
Worsley, K.J.4
Narayanan, S.5
Francis, G.S.6
Antel, J.P.7
Wolfson, C.8
Arnold, D.L.9
-
12
-
-
3242814526
-
FK506 and a nonimmunosuppressant derivative reduce axonal and myelin damage in experimental autoimmune encephalomyelitis: Neuroimmunophilin ligand-mediated neuroprotection in a model of multiple sclerosis
-
Gold B. G., Voda J., Yu X., Mckeon G. and Bourdette D. N. (2004) FK506 and a nonimmunosuppressant derivative reduce axonal and myelin damage in experimental autoimmune encephalomyelitis: neuroimmunophilin ligand-mediated neuroprotection in a model of multiple sclerosis. J. Neurosci. Res. 77, 367-377.
-
(2004)
J. Neurosci. Res.
, vol.77
, pp. 367-377
-
-
Gold, B.G.1
Voda, J.2
Yu, X.3
Mckeon, G.4
Bourdette, D.N.5
-
13
-
-
0242330842
-
Myelin-associated inhibitors of axon regeneration
-
Grados-Munro E. M. and Fournier A. E. (2003) Myelin-associated inhibitors of axon regeneration. J. Neurosci. Res. 74, 479-485.
-
(2003)
J. Neurosci. Res.
, vol.74
, pp. 479-485
-
-
Grados-Munro, E.M.1
Fournier, A.E.2
-
14
-
-
12144289376
-
Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch
-
Huan J., Subramanian S., Jones R., Rich C., Link J., Mooney J., Bourdette D. N., Vandenbark A. A., Burrows G. G. and Offner H. (2004) Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch. J. Immunol. 172, 4556-4566.
-
(2004)
J. Immunol.
, vol.172
, pp. 4556-4566
-
-
Huan, J.1
Subramanian, S.2
Jones, R.3
Rich, C.4
Link, J.5
Mooney, J.6
Bourdette, D.N.7
Vandenbark, A.A.8
Burrows, G.G.9
Offner, H.10
-
15
-
-
1642482932
-
Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation
-
Inglese M., Mancardi G. L., Pagani E., Rocca M. A., Murialdo A., Saccardi R., Comi G. and Filippi M. (2004) Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation. J. Neurol. Neurosurg Psychiatry 75, 643-644.
-
(2004)
J. Neurol. Neurosurg Psychiatry
, vol.75
, pp. 643-644
-
-
Inglese, M.1
Mancardi, G.L.2
Pagani, E.3
Rocca, M.A.4
Murialdo, A.5
Saccardi, R.6
Comi, G.7
Filippi, M.8
-
16
-
-
0037369638
-
Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases
-
Kerschensteiner M., Stadelmann C., Dechant G., Wekerle H. and Hohlfeld R. (2003) Neurotrophic cross-talk between the nervous and immune systems: implications for neurological diseases. Ann. Neurol. 53, 292-304.
-
(2003)
Ann. Neurol.
, vol.53
, pp. 292-304
-
-
Kerschensteiner, M.1
Stadelmann, C.2
Dechant, G.3
Wekerle, H.4
Hohlfeld, R.5
-
17
-
-
29444435085
-
Galactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice
-
Kondo Y., Wenger D. A., Gallo V. and Duncan I. D. (2005) Galactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice. Proc. Natl Acad. Sci. USA 102, 18 670-18 675.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 18670-18675
-
-
Kondo, Y.1
Wenger, D.A.2
Gallo, V.3
Duncan, I.D.4
-
18
-
-
26444459836
-
EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans
-
Koprivica V., Cho K. S., Park J. B., Yiu G., Atwal J., Gore B., Kim J. A., Lin E., Tessier-Lavigne M., Chen D. F. and He Z. (2005) EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science 310, 106-110.
-
(2005)
Science
, vol.310
, pp. 106-110
-
-
Koprivica, V.1
Cho, K.S.2
Park, J.B.3
Yiu, G.4
Atwal, J.5
Gore, B.6
Kim, J.A.7
Lin, E.8
Tessier-Lavigne, M.9
Chen, D.F.10
He, Z.11
-
19
-
-
33748174765
-
Preclinical studies demonstrate rapid and potent modulation of experimental encephalomyelitis in humanized DR2+ transgenic mice treated with a soluble recombinant TCR ligand containing DR2/MOG-35-55 peptide
-
submitted
-
Link J. M., Rich C. M., Korat M., Burrows G. G., Offner H. and Vandenbark A. A. (2006) Preclinical studies demonstrate rapid and potent modulation of experimental encephalomyelitis in humanized DR2+ transgenic mice treated with a soluble recombinant TCR ligand containing DR2/MOG-35-55 peptide. Clin. Immunol., submitted.
-
(2006)
Clin. Immunol.
-
-
Link, J.M.1
Rich, C.M.2
Korat, M.3
Burrows, G.G.4
Offner, H.5
Vandenbark, A.A.6
-
20
-
-
27444443629
-
Multiple sclerosis trial designs for the 21 (st) century: Building on recent lessons
-
Lublin F. (2005) Multiple sclerosis trial designs for the 21 (st) century: Building on recent lessons. J. Neurol. 252:: v46-v53.
-
(2005)
J. Neurol.
, vol.252
-
-
Lublin, F.1
-
21
-
-
0035838312
-
Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS
-
Mancardi G. L., Saccardi R., Filippi M. et al. (2001) Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS. Neurology 57, 62-68.
-
(2001)
Neurology
, vol.57
, pp. 62-68
-
-
Mancardi, G.L.1
Saccardi, R.2
Filippi, M.3
-
22
-
-
0033049143
-
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
-
Moalem G., Leibowitz-Amit R., Yoles E., Mor F., Cohen I. R. and Schwartz M. (1999) Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nat Med. 5, 49-55.
-
(1999)
Nat Med.
, vol.5
, pp. 49-55
-
-
Moalem, G.1
Leibowitz-Amit, R.2
Yoles, E.3
Mor, F.4
Cohen, I.R.5
Schwartz, M.6
-
23
-
-
1542267742
-
Direct impact of T cells on neurons revealed by two-photon microscopy in living brain tissue
-
Nitsch R., Pohl E. E., Smorodchenko A., Infante-Duarte C., Aktas O. and Zipp F. (2004) Direct impact of T cells on neurons revealed by two-photon microscopy in living brain tissue. J. Neurosci. 24, 2458-2464.
-
(2004)
J. Neurosci.
, vol.24
, pp. 2458-2464
-
-
Nitsch, R.1
Pohl, E.E.2
Smorodchenko, A.3
Infante-Duarte, C.4
Aktas, O.5
Zipp, F.6
-
24
-
-
24744452162
-
Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury
-
Offner H., Subramanian S., Wang C., Afentoulis M., Vandenbark A. A., Huan J. and Burrows G. G. (2005) Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury. J. Immunol. 175, 4103-4111.
-
(2005)
J. Immunol.
, vol.175
, pp. 4103-4111
-
-
Offner, H.1
Subramanian, S.2
Wang, C.3
Afentoulis, M.4
Vandenbark, A.A.5
Huan, J.6
Burrows, G.G.7
-
25
-
-
30444442133
-
Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat
-
Papadopoulos D., Pham-Dinh D. and Reynolds R. (2006) Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat. Exp Neurol. 197, 373-385.
-
(2006)
Exp Neurol.
, vol.197
, pp. 373-385
-
-
Papadopoulos, D.1
Pham-Dinh, D.2
Reynolds, R.3
-
26
-
-
0033958462
-
Glutamate excitotoxicity in a model of multiple sclerosis
-
Pitt D., Werner P. and Raine C. S. (2000) Glutamate excitotoxicity in a model of multiple sclerosis. Nat Med. 6, 67-70.
-
(2000)
Nat Med.
, vol.6
, pp. 67-70
-
-
Pitt, D.1
Werner, P.2
Raine, C.S.3
-
27
-
-
0038605526
-
Axonal injury in multiple sclerosis
-
Rammohan K. W. (2003) Axonal injury in multiple sclerosis. Curr. Neurol. Neurosci. Rep 3, 231-237.
-
(2003)
Curr. Neurol. Neurosci. Rep
, vol.3
, pp. 231-237
-
-
Rammohan, K.W.1
-
28
-
-
0035426664
-
Multiple sclerosis: More than inflammation and demyelination
-
Rieckmann P. and Smith K. J. (2001) Multiple sclerosis: more than inflammation and demyelination. Trends Neurosci. 24, 435-437.
-
(2001)
Trends Neurosci.
, vol.24
, pp. 435-437
-
-
Rieckmann, P.1
Smith, K.J.2
-
29
-
-
20444422539
-
Protective autoimmunity and neuroprotection in inflammatory and noninflammatory neurodegenerative diseases
-
Schwartz M. and Kipnis J. (2005) Protective autoimmunity and neuroprotection in inflammatory and noninflammatory neurodegenerative diseases. J. Neurol. Sci. 233, 163-166.
-
(2005)
J. Neurol. Sci.
, vol.233
, pp. 163-166
-
-
Schwartz, M.1
Kipnis, J.2
-
30
-
-
0029939467
-
Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
-
Steinman L. (1996) Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 85, 299-302.
-
(1996)
Cell
, vol.85
, pp. 299-302
-
-
Steinman, L.1
-
31
-
-
0035278914
-
Cytokines and the central nervous system
-
Szelényi J. (2001) Cytokines and the central nervous system. Brain Res. Bull. 54, 329-338.
-
(2001)
Brain Res. Bull.
, vol.54
, pp. 329-338
-
-
Szelényi, J.1
-
32
-
-
0032576752
-
Axonal transection in the lesions of multiple sclerosis
-
Trapp B. D., Peterson J., Ransohoff R. M., Rudick R., Mork S. and Bo L. (1998) Axonal transection in the lesions of multiple sclerosis. N Engl. J. Med. 338, 278-285.
-
(1998)
N Engl. J. Med.
, vol.338
, pp. 278-285
-
-
Trapp, B.D.1
Peterson, J.2
Ransohoff, R.M.3
Rudick, R.4
Mork, S.5
Bo, L.6
-
33
-
-
0037869060
-
Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice
-
Vandenbark A. A., Rich C., Mooney J., Zamora A., Wang C., Huan J., Fugger L., Offner H., Jones R. and Burrows G. G. (2003) Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice. J. Immunol. 171, 127-133.
-
(2003)
J. Immunol.
, vol.171
, pp. 127-133
-
-
Vandenbark, A.A.1
Rich, C.2
Mooney, J.3
Zamora, A.4
Wang, C.5
Huan, J.6
Fugger, L.7
Offner, H.8
Jones, R.9
Burrows, G.G.10
-
34
-
-
0043136755
-
Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation
-
Wang C., Mooney J. L., Meza-Romero R., Chou Y. K., Huan J., Vandenbark A. A., Offner H. and Burrows G. G. (2003) Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation. J. Immunol. 171, 1934-1940.
-
(2003)
J. Immunol.
, vol.171
, pp. 1934-1940
-
-
Wang, C.1
Mooney, J.L.2
Meza-Romero, R.3
Chou, Y.K.4
Huan, J.5
Vandenbark, A.A.6
Offner, H.7
Burrows, G.G.8
-
35
-
-
0032576636
-
Demyelinating diseases - New pathological insights, new therapeutic targets
-
Waxman S. G. (1998) Demyelinating diseases - new pathological insights, new therapeutic targets. N Engl. J. Med. 338, 323-325.
-
(1998)
N Engl. J. Med.
, vol.338
, pp. 323-325
-
-
Waxman, S.G.1
|