Preparation, biochemical characterization and biological properties of radiolabelled N-alkylated deoxynojirimycins

Biochemical Journal

Volumn 366, Issue 1, 2002, Pages 225-233

  Mellor, Howard R ^a   Nolan, James ^a   Pickering, Lea ^a   Wormald, Mark R ^a   Platt, Frances M ^a   Dwek, Raymond A ^a   Fleet, George W J ^a   Butters, Terry D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Glucosyltransferase; Hydrophobic; Imino sugar; Inhibitor; Tissue uptake

Indexed keywords

ALDEHYDES; ALKYLATION; CELLS; ENZYME INHIBITION; SODIUM COMPOUNDS; TISSUE CULTURE;

CYTOTOXICITY;

SUGARS;

ALDEHYDE; ALPHA GLUCOSIDASE; DEOXYNOJIRIMYCIN; GLUCOSYLTRANSFERASE; NOJIRIMYCIN; PROTEIN; UNCLASSIFIED DRUG;

ABSORPTION; ALKYLATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROPHOBICITY; ISOTOPE LABELING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT; PROTON NUCLEAR MAGNETIC RESONANCE; TIME; TISSUE DISTRIBUTION;

1-DEOXYNOJIRIMYCIN; ALKYLATION; ANIMALS; BRAIN; CATTLE; CELL DIVISION; CELL LINE; ENZYME INHIBITORS; GLYCOLIPIDS; KINETICS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, CHEMICAL; TIME FACTORS; TISSUE DISTRIBUTION;

ANIMALIA; LEUCISCUS IDUS;

EID: 0037103782     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020466     Document Type: Article

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