Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 1, 2010, Pages 415-425

  Patil, Vishal ^a   Guerrant, William ^a   Chen, Po C ^a   Gryder, Berkley ^a   Benicewicz, Derek B ^a   Khan, Shabana I ^b   Tekwani, Babu L ^b   Oyelere, Adegboyega K ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Aryltriazolylhydroxamates; Histone deacetylase; Leishmania donovani; Leishmaniasis; Malaria; Plasmodium falciparum; Structure activity relationship

Indexed keywords

7 (2 TOLYL)TRIAZOLYLHEPTAHYDROXAMAMIC ACID; 7 (3 PYRIDYL) TRIAZOLYLHEPTAHYDROXAMIC ACID; 8 (3 BIPHENYL)TRIAZOLYLOCTAHYDROXAMIC ACID; 8 (3 PYRIDYL)TRIAZOLYLOCTAHYDROXAMIC ACID; 8 (4 PYRIDYLPHENYL)TRIAZOLYLOCTAHYDROXAMAMIC ACID; 8 (6 METHOXYNAPTHYL)TRIAZOLYLHEPTAOCTAHYDROXAMAMIC ACID; 8 (N,N DIMETHYLANILYL)TRIAZOLYLOCTAHYDROXAMIC ACID; 8 (PHENYL)TRIAZOLYLOCTAHYDROXAMIC ACID; 9 (3 BIPHENYL)TRIAZOLYLNONAHYDROXAMIC ACID; 9 (N,N DIMETHYLANILYL)TRIAZOLYLNONAHYDROXAMIC ACID; 9 (PHENYL)TRIAZOLYLNONAHYDROXAMIC ACID; ANTIMALARIAL AGENT; HISTONE DEACETYLASE INHIBITOR; MILTEFOSINE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIMALARIAL ACTIVITY; ARTICLE; CYTOTOXICITY; NONHUMAN; STRUCTURE ACTIVITY RELATION; VISCERAL LEISHMANIASIS;

ANTIMALARIALS; ANTIPROTOZOAL AGENTS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; LEISHMANIA DONOVANI; LEISHMANIASIS; MALARIA; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

LEISHMANIA DONOVANI; PLASMODIUM FALCIPARUM; PLASMODIUM PARASITES; PROTOZOA; TRYPANOSOMATIDAE;

EID: 72049116798     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.10.042     Document Type: Article

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