Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 9, 2008, Pages 5254-5265

  Mukherjee, Prasenjit ^a   Pradhan, Anupam ^a   Shah, Falgun ^a   Tekwani, Babu L ^a,b   Avery, Mitchell A ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Docking; Histone deacetylase; Homology modeling; Molecular dynamics; Plasmodium falciparum

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISIN; CHLOROQUINE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG TARGETING; ENZYME STRUCTURE; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURAL HOMOLOGY; STRUCTURAL PROTEOMICS;

ALGORITHMS; ANIMALS; ANTIMALARIALS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PREDICTIVE VALUE OF TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 43049091210     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.03.005     Document Type: Article

References (31)

1. Choi S., Mukherjee P., and Avery M. Curr. Med. Chem. 15 (2008) 161-171
2. Weinmann H., and Ottow E. Annu. Rep. Med. Chem. 39 (2004) 185-196
3. de Ruijter A.J.M., van Gennip A.H., Caron H.N., Kemp S., and van Kuilenburg A.B.P. Biochem. J. 370 (2003) 737-749
4. Longhurst H.J., and Holder A.A. Mol. Biochem. Parasitol. 69 (1995) 111-113
5. Creedon K.A., Kaslow D.C., Rathod P.K., and Wellems T.E. Mol. Biochem. Parasitol. 54 (1992) 113-115
6. Bennett B.J., Thompson J., and Coppel R.L. Mol. Biochem. Parasitol. 70 (1995) 231-233
7. Joshi M.B., Lin D.T., Chiang P.H., Goldman N.D., Fujioka H., Aikawa M., and Syin C. Mol. Biochem. Parasitol. 99 (1999) 11-19
8. Merrick C.J., and Duraisingh M.T. Eukaryot. Cell 6 (2007) 2081-2091
9. Singh S.B., Zink D.L., Polishook J.D., Dombrowski A.W., Darkin-Rattray S.J., Schmatz D.M., and Goetz M.A. Tetrahedron Lett. 37 (1996) 8077-8080
10. Darkin-Rattray S.J., Gurnett A.M., Myers R.W., Dulski P.M., Crumley T.M., Allocco J.J., Cannova C., Meinke P.T., Colletti S.L., Bednarek M.A., Singh S.B., Goetz M.A., Dombrowski A.W., Polishook J.D., and Schmatz D.M. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 13143-13147
11. Meinke P.T., Colletti S.L., Doss G., Myers R.W., Gurnett A.M., Dulski P.M., Darkin-Rattray S.J., Allocco J.J., Galuska S., Schmatz D.M., Wyvratt M.J., and Fisher M.H. J. Med. Chem. 43 (2000) 4919-4922
12. Mai A., Cerbara I., Valente S., Massa S., Walker L.A., and Tekwani B.L. Antimicrob. Agents Chemother. 48 (2004) 1435-1436
13. Andrews K.T., Walduck A., Kelso M.J., Fairlie D.P., Saul A., and Parsons P.G. Int. J. Parasitol. 30 (2000) 761-768
14. Parsons P.G., Hansen C., Fairlie D.P., West M.L., Danoy P.A., Sturm R.A., Dunn I.S., Pedley J., and Ablett E.M. Biochem. Pharmacol. 53 (1997) 1719-1724
15. Sabnis Y.A., Desai P.V., Rosenthal P.J., and Avery M.A. Protein Sci. 12 (2003) 501-509
16. Sabnis Y., Rosenthal P.J., Desai P., and Avery M.A. J. Biomol. Struct. Dyn. 19 (2002) 765-774
17. Patny A., Desai P.V., and Avery M.A. Proteins 65 (2006) 824-842
18. Desai P.V., and Avery M.A. J. Biomol. Struct. Dyn. 21 (2004) 781-790
19. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D.J. J. Mol. Biol. 215 (1990) 403-410
20. Somoza J.R., Skene R.J., Katz B.A., Mol C., Ho J.D., Jennings A.J., Luong C., Arvai A., Buggy J.J., Chi E., Tang J., Sang B.C., Verner E., Wynands R., Leahy E.M., Dougan D.R., Snell G., Navre M., Knuth M.W., Swanson R.V., McRee D.E., and Tari L.W. Structure 12 (2004) 1325-1334
21. Finnin M.S., Donigian J.R., Cohen A., Richon V.M., Rifkind R.A., Marks P.A., Breslow R., and Pavletich N.P. Nature 401 (1999) 188-193
22. Godzik A., Kolinski A., and Skolnick J. J. Mol. Biol. 227 (1992) 227-238
23. Laskowski R.A., Moss D.S., and Thornton J.M. J. Mol. Biol. 231 (1993) 1049-1067
24. Ayer D.E. Trends Cell Biol. 9 (1999) 193-198
25. Tsai S.C., and Seto E. J. Biol. Chem. 277 (2002) 31826-31833
26. David G., Neptune M.A., and DePinho R.A. J. Biol. Chem. 277 (2002) 23658-23663
27. Hassig C.A., Tong J.K., Fleischer T.C., Owa T., Grable P.G., Ayer D.E., and Schreiber S.L. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 3519-3524
28. Kadosh D., and Struhl K. Genes Dev. 12 (1998) 797-805
29. Bairoch A., and Apweiler R. Nucleic Acids Res. 25 (1997) 31-36
30. Makler M.T., Ries J.M., Williams J.A., Bancroft J.E., Piper R.C., Gibbins B.L., and Hinrichs D.J. Am. J. Trop. Med. Hyg. 48 (1993) 739-741
31. Makler M.T., and Hinrichs D.J. Am. J. Trop. Med. Hyg. 48 (1993) 205-210