Perfluorononanoic acid-induced apoptosis in rat spleen involves oxidative stress and the activation of caspase-independent death pathway

Toxicology

Volumn 267, Issue 1-3, 2010, Pages 54-59

  Fang, Xuemei ^a,b   Feng, Yixing ^a   Wang, Jianshe ^a   Dai, Jiayin ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b Suzhou Teachers' College   (China)

Author keywords

AIF; Apoptosis; Oxidative stress; PFNA; Spleen

Indexed keywords

ALKANOIC ACID; APOPTOSIS INDUCING FACTOR; CARBON; CASPASE; CASPASE 3; CASPASE 8; CYTOKINE; FAS ASSOCIATED DEATH DOMAIN PROTEIN; HYDROGEN PEROXIDE; PERFLUORONONANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EXPOSURE; DRUG MEGADOSE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPLEEN CELL; UPREGULATION;

ANIMALS; APOPTOSIS; DNA NUCLEOTIDYLEXOTRANSFERASE; FATTY ACIDS; GENE EXPRESSION; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; LYMPHOCYTES; MALE; ORGAN SIZE; OXIDATIVE STRESS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPLEEN; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 71849112370     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.10.020     Document Type: Article

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