Carbonic anhydrase II-induced selection of inhibitors from a dynamic combinatorial library of Schiff's bases

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 21, 2009, Pages 6014-6017

  Nasr, Gihane ^a   Petit, Eddy ^a   Supuran, Claudiu T ^b   Winum, Jean Yves ^c   Barboiu, Mihail ^a  

^a CNRS   (France)

^b UNIVERSITY OF FLORENCE   (Italy)

^c INSTITUT CHARLES GERHARDT   (France)

Author keywords

Carbonic anhydrase; Dynamic combinatorial library; HPLC; Isozyme selective inhibitor; Schiff's base; Sulfonamide

Indexed keywords

CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; IMINE; ISOENZYME; SCHIFF BASE; SULFONAMIDE;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CHEMISTRY; COMBINATORIAL LIBRARY; CONTROLLED STUDY; COVALENT BOND; DRUG BINDING; ENZYME BINDING; INTERCONVERSION; THERMODYNAMICS;

CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CATALYTIC DOMAIN; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; HUMANS; SCHIFF BASES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; THERMODYNAMICS;

EID: 71849109451     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.047     Document Type: Article

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