Carbonic anhydrase-encoded dynamic constitutional libraries: Toward the discovery of isozyme-specific inhibitors

Journal of Medicinal Chemistry

Volumn 52, Issue 15, 2009, Pages 4853-4859

  Nasr, Gihane ^a   Petit, Eddy ^a   Vullo, Daniela ^b   Winum, Jean Yves ^c   Supuran, Claudiu T ^b   Barboiu, Mihail ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIVERSITY OF FLORENCE   (Italy)

^c INSTITUT CHARLES GERHARDT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; AMINE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CARBONYL DERIVATIVE; IMINE; ISOENZYME; N (2 FLUOROBENZYL)(4 SULFONAMIDE PHENYL)ETHANAMINE; N (3 CARBOXYBENZYL)(4 SULFONAMIDE PHENYL)ETHANAMINE; N (5 METHANE 2 FURANSULFONIC ACID)(4 SULFONAMIDE PHENYL)ETHANAMINE; N (5 METHANE 2 FURANSULFONIC ACID)(PHENYL)METHANAMINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL BOND; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DISCOVERY; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 68549101744     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900449v     Document Type: Article

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