Structure-activity relationship of bile alcohols as human farnesoid X receptor agonist

Steroids

Volumn 75, Issue 1, 2010, Pages 95-100

  Iguchi, Yusuke ^a,b   Kihira, Kenji ^b   Nishimaki Mogami, Tomoko ^c   Une, Mizuho ^a  

^a HIROSHIMA INTERNATIONAL UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Bile alcohol; Farnesoid X receptor; Structure activity relationship

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BETA GALACTOSIDASE; BILE ACID; BILE ALCOHOL DERIVATIVE; FARNESOID X RECEPTOR; FARNESOID X RECEPTOR STIMULATING AGENT; HYDROXYL GROUP; LUCIFERASE; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BILE ACID METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; CHOLESTANOLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUCIFERASES; MOLECULAR STRUCTURE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 71849086198     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2009.11.002     Document Type: Article

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