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Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 23, 2009, Pages 6502-6506

Synthesis and SAR of novel, non-MPEP chemotype mGluR5 NAMs identified by functional HTS

(6) Zhou, Ya a Rodriguez, Alice L a Williams, Richard a Weaver, C David a Conn, P Jeffrey a Lindsley, Craig W a,b

a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE (United States)

b VANDERBILT UNIVERSITY (United States)

Author keywords

mGluR5; Negative allosteric modulator; Positive allosteric modulator

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; METABOTROPIC RECEPTOR 5;

ALLOSTERISM; ARTICLE; CHEMICAL STRUCTURE; IC 50; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BENZAMIDES; BENZIMIDAZOLES; HIGH-THROUGHPUT SCREENING ASSAYS; MOLECULAR STRUCTURE; PHTHALIMIDES; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 71749106942 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2009.10.059 Document Type: Article

Times cited : (19)

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