Steroid hormone fluctuations and GABAAR plasticity

Psychoneuroendocrinology

Volumn 34, Issue SUPPL. 1, 2009, Pages

  Maguire, Jamie ^a   Mody, Istvan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

GABAA receptors; Neurosteroids; Ovarian cycle; Pregnancy; Steroid hormones; Stress

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA SUBUNIT; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2 SUBUNIT; PROGESTERONE; STEROID HORMONE; UNCLASSIFIED DRUG;

ANESTHESIA; ARTICLE; CENTRAL NERVOUS SYSTEM; GABAERGIC SYSTEM; HORMONAL REGULATION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INHIBITORY POSTSYNAPTIC POTENTIAL; MOOD DISORDER; NERVE EXCITABILITY; NEUROLOGIC DISEASE; NONHUMAN; OVARY CYCLE; PATHOPHYSIOLOGY; PERIAQUEDUCTAL GRAY MATTER; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUERPERAL DEPRESSION; SEDATION; SEIZURE; STRESS; SYNAPTIC INHIBITION;

ANIMALS; BRAIN; FEMALE; HUMANS; MALE; MENSTRUAL CYCLE; MICE; NEURONAL PLASTICITY; NEURONS; NEUROTRANSMITTER AGENTS; PREGNANCY; RECEPTORS, GABA-A; SEIZURES; STRESS, PHYSIOLOGICAL;

EID: 71249118688     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2009.06.019     Document Type: Article

References (72)

1. Akinci M.K., and Johnston G.A. Sex differences in acute swim stress-induced changes in the binding of MK-801 to the NMDA subclass of glutamate receptors in mouse forebrain. Journal of Neurochemistry 61 (1993) 2290-2293
2. Aldahan M.I., Tehrani M.H.J., and Thalmann R.H. Regulation of gamma-aminobutyric acid(B) (GABA(B)) receptors in cerebral-cortex during the estrous-cycle. Brain Research 640 (1994) 33-39
3. Backstrom T., et al. Pathogenesis in menstrual cycle-linked CNS disorders. Steroids and the Nervous System 1007 (2003) 42-53
4. Barbaccia M.L., Concas A., Roscetti G., Bolacchi F., Mostallino M.C., Purdy R.H., and Biggio G. Stress-induced increase in brain neuroactive steroids: antagonism by abecarnil. Pharmacology Biochemistry and Behavior 54 (1996) 205-210
5. Barbaccia M.L., Roscetti G., Trabucchi M., Mostallino M.C., Concas A., Purdy R.H., and Biggio G. Time-dependent changes in rat brain neuroactive steroid concentrations and GABA(A) receptor function after acute stress. Neuroendocrinology 63 (1996) 166-172
6. Barbaccia M.L., Serra M., Purdy R.H., and Biggio G. Stress and neuroactive steroids. Neurosteroids and Brain Function 46 (2001) 243-272
7. Belelli D., Casula A., Ling A., and Lambert J.J. The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors. Neuropharmacology 43 (2002) 651-661
8. Belelli D., and Lambert J.J. Neurosteroids: endogenous regulators of the GABA(A) receptor. Nature Reviews Neuroscience 6 (2005) 565-575
9. Bloch M., Schmidt P.J., Danaceau M., Murphy J., Nieman L., and Rubinow D.R. Effects of gonadal steroids in women with a history of postpartum depression. American Journal of Psychiatry 157 (2000) 924-930
10. Bremner J.D., Innis R.B., White T., Fujita M., Silbersweig D., Goddard A.W., Staib L., Stern E., Cappiello A., Woods S., Baldwin R., and Charney D.S. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 47 (2000) 96-106
11. Brown N., Kerby J., Bonnert T.P., Whiting P.J., and Wafford K.A. Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors. British Journal of Pharmacology 136 (2002) 965-974
12. Concas A., Mostallino M.C., Porcu P., Follesa P., Barbaccia M.L., Trabucchi M., Purdy R.H., Grisenti P., and Biggio G. Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery. Proceedings of the National Academy of Sciences of the United States of America 95 (1998) 13284-13289
13. Farrant M., and Nusser Z. Variations on an inhibitory theme: Phasic and tonic activation of GABA(A) receptors. Nature Reviews Neuroscience 6 (2005) 215-229
14. Follesa P., Floris S., Tuligi G., Mostallino M.C., Concas A., and Biggio G. Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain. European Journal of Neuroscience 10 (1998) 2905-2912
15. Girdler S.S., and Klatzkin R. Neurosteroids in the context of stress: implications for depressive disorders. Pharmacology and Therapeutics 116 (2007) 125-139
16. Goddard A.W., Mason G.F., Almai A., Rothman D.L., Behar K.L., Petroff O.A.C., Charney D.S., and Krystal J.H. Reductions in occipital cortex GABA levels in panic disorder detected with H-1-magnetic resonance spectroscopy. Archives of General Psychiatry 58 (2001) 556-561
17. Griffiths J., and Lovick T. Withdrawal from progesterone increases expression of alpha4, beta1, and delta GABA(A) receptor subunits in neurons in the periaqueductal gray matter in female Wistar rats. The Journal of Comparative Neurology 486 (2005) 89-97
18. Griffiths J.L., and Lovick T.A. GABAergic neurones in the rat periaqueductal grey matter express alpha4, beta1 and delta GABAA receptor subunits: plasticity of expression during the estrous cycle. Neuroscience 136 (2005) 457-466
19. Gulinello M., Gong Q.H., Li X., and Smith S.S. Short-term exposure to a neuroactive steroid increases alpha 4 GABA(A) receptor subunit levels in association with increased anxiety in the famale rat. Brain Research 910 (2001) 55-66
20. Herd M.B., Belelli D., and Lambert J.J. Neurosteroid modulation of synaptic and extrasynaptic GABA(A) receptors. Pharmacology and Therapeutics 116 (2007) 20-34
21. Herzog A.G., Harden C.L., Liporace J., Pennell P., Schomer D.L., Sperling M., Fowler K., Nikolov B., Shuman S., and Newman M. Frequency of catamenial seizure exacerbation in women with localization-related epilepsy. Annals of Neurology 56 (2004) 431-434
22. Herzog A.G., Klein P., and Ransil B.J. Three patterns of catamenial epilepsy. Epilepsia 38 (1997) 1082-1088
23. A channel subtypes. Molecular Neurobiology 18 (1998) 35-86
24. Hosie A.M., Clarke L., da S.H., and Smart T.G. Conserved site for neurosteroid modulation of GABA A receptors. Neuropharmacology 56 (2009) 149-154
25. Hosie A.M., Wilkins M.E., da Silva H.M., and Smart T.G. Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites. Nature 444 (2006) 486-489
26. Hsu F.C., and Smith S.S. Progesterone withdrawal reduces paired-pulse inhibition in rat hippocampus: dependence on GABA(A) receptor alpha 4 subunit upregulation. Journal of Neurophysiology 89 (2003) 186-198
27. Longone P., Rupprecht R., Manieri G.A., Bernardi G., Romeo E., and Pasini A. The complex roles of neurosteroids in depression and anxiety disorders. Neurochemistry International 52 (2008) 596-601
28. Maguire, J., Ferando, I., Simonsen, C., Mody, I., 2009. Excitability changes related to GABAA receptor plasticity during pregnancy. The Journal of Neuroscience 29 (30), in press.
29. Maguire J., and Mody I. GABA(A)R plasticity during pregnancy: relevance to postpartum depression. Neuron 59 (2008) 207-213
30. Maguire J., and Mody I. Neurosteroid synthesis-mediated regulation of GABA(A) receptors: relevance to the ovarian cycle and stress. The Journal of Neuroscience 27 (2007) 2155-2162
31. Maguire J.L., Stell B.M., Rafizadeh M., and Mody I. Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety. Nature Neuroscience 8 6 (2005) 797-804
32. Malizia A.L., Cunningham V.J., Bell C.J., Liddle P.F., Jones T., and Nutt D.J. Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder-preliminary results from a quantitative PET study. Archives of General Psychiatry 55 (1998) 715-720
33. Martin J.V., and Williams D.B. Benzodiazepine binding varies with stage of estrous-cycle in unwashed membranes from mouse-brain. Life Sciences 57 (1995) 1903-1909
34. Mcewen B.S. The neurobiology and neuroendocrinology of stress implications for post-traumatic stress disorder from a basic science perspective. Psychiatric Clinics of North America 25 (2002) 469
35. Mihalek R.M., Banerjee P.K., Korpi E.R., Quinlan J.J., Firestone L.L., Mi Z.P., Lagenaur C., Tretter V., Sieghart W., Anagnostaras S.G., Sage J.R., Fanselow M.S., Guidotti A., Spigelman I., Li Z.W., DeLorey T.M., Olsen R.W., and Homanics G.E. Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice. Proceedings of the National Academy of Sciences of the United States of America 96 (1999) 12905-12910
36. Mitchell E.A., Herd M.B., Gunn B.G., Lambert J.J., and Belelli D. Neurosteroid modulation of GABAA receptors: molecular determinants and significance in health and disease. Neurochemistry International 52 (2008) 588-595
37. Mody I., and Pearce R.A. Diversity of inhibitory neurotransmission through GABAA receptors. Trends in Neurosciences 27 (2004) 569-575
38. Molina-Hernandez M., Contreras C.M., and Tellez-Alcantara P. Diazepam increases the number of punished responses in a conflict-operant paradigm during late proestrus and estrus in the Wistar rat. Neuropsychobiology 43 (2001) 29-33
39. Molina-Hernandez M., and Tellez-Alcantara N.P. Estrus variation in anticonflict effects of midazolam microinjected into septal nuclei in female Wistar rats. Pharmacology Biochemistry and Behavior 68 (2001) 531-537
40. Nusser Z., Sieghart W., and Somogyi P. Segregation of different GABA(A) receptors to synaptic and extrasynaptic membranes of cerebellar granule cells. The Journal of Neuroscience 18 (1998) 1693-1703
41. Olsen R.W., and Sieghart W. International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Pharmacological Reviews 60 (2008) 243-260 (update)
42. Paul S.M., and Purdy R.H. Neuroactive Steroids. Faseb Journal 6 (1992) 2311-2322
43. Peng Z., Hauer B., Mihalek R.M., Homanics G.E., Sieghart W., Olsen R.W., and Houser C.R. GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha 4 and gamma 2 subunits in the forebrain. Journal of Comparative Neurology 446 (2002) 179-197
44. Peng Z.C., Huang C.S., Stell B.M., Mody I., and Houser C.R. Altered expression of the delta subunit of the GABA(A) receptor in a mouse model of temporal lobe epilepsy. The Journal of Neuroscience 24 (2004) 8629-8639
45. Pericic D., Jazvinscak M., Svob D., and Mirkovic K. Swim stress alters the behavioural response of mice to GABA-related and some GABA-unrelated convulsants. Epilepsy Research 43 (2001) 145-152
46. Petursson H. The benzodiazepine withdrawal syndrome. Addiction 89 (1994) 1455-1459
47. Pirker S., Schwarzer C., Wieselthaler A., Sieghart W., and Sperk G. GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. Neuroscience 101 (2000) 815-850
48. Purdy R.H., Morrow A.L., Moore P.H., and Paul S.M. Stress-induced elevations of gamma-aminobutyric-acid type-A receptor-active steroids in the rat-brain. Proceedings of the National Academy of Sciences of the United States of America 88 (1991) 4553-4557
49. Reddy D.S. Is there a physiological role for the neurosteroid THDOC in stress-sensitive conditions?. Trends in Pharmacological Sciences 24 (2003) 103-106
50. Reddy D.S., and Kulkarni S.K. Sex and estrous cycle-dependent changes in neurosteroid and benzodiazepine effects on food consumption and plus-maze learning behaviors in rats. Pharmacology Biochemistry and Behavior 62 (1999) 53-60
51. Reddy D.S., and Rogawski M.A. Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility. The Journal of Neuroscience 22 (2002) 3795-3805
52. Sanna E., Mostallino M.C., Murru L., Carta M., Talani G., Zucca S., Mura M.L., Maciocco E., and Biggio G. Changes in expression and function of extrasynaptic GABAA receptors in the rat hippocampus during pregnancy and after delivery. The Journal of Neuroscience 29 (2009) 1755-1765
53. Schwartz R.D., Wess M.J., Labarca R., Skolnick P., and Paul S.M. Acute stress enhances the activity of the gaba receptor-gated chloride-ion channel in brain. Brain Research 411 (1987) 151-155
54. Serra M., Pisu M.G., Littera M., Papi G., Sanna E., Tuveri F., Usala L., Purdy R.H., and Biggio G. Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain. Journal of Neurochemistry 75 (2000) 732-740
55. Skerritt J.H., Trisdikoon P., and Johnston G.A. Increased GABA binding in mouse brain following acute swim stress. Brain Research 215 (1981) 398-403
56. Smith M.J., Adams L.F., Schmidt P.J., Rubinow D.R., and Wassermann E.M. Abnormal luteal phase excitability of the motor cortex in women with premenstrual syndrome. Biological Psychiatry 54 (2003) 757-762
57. Smith S.S., Gong Q.H., Hsu F.C., Markowitz R.S., ffrench-Mullen J.M.H., and Li H.S. GABA(A) receptor alpha 4 subunit suppression prevents withdrawal properties of an endogenous steroid. Nature 392 (1998) 926-930
58. Smith S.S., Shen H., Gong Q.H., and Zhou X. Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits. Pharmacological and Therapeutics 116 (2007) 58-76
59. Spigelman I., Li Z.W., Liang J., Cagetti E., Samzadeh S., Mihalek R.M., Homanics G.E., and Olsen R.W. Reduced inhibition and sensitivity to neurosteroids in hippocampus of mice lacking the GABA(A) receptor delta subunit. Journal of Neurophysiology 90 (2003) 903-910
60. A receptors. Proceedings of the National Academy of Sciences of the United States of America 100 (2003) 14439-14444
61. Stoffel-Wagner B. Neurosteroid metabolism in the human brain. European Journal of Endocrinology 145 (2001) 669-679
62. Strohle A., Romeo E., di Michele F., Pasini A., Yassouridis A., Holsboer F., and Rupprecht R. GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment. American Journal of Psychiatry 159 (2002) 145-147
63. Sundstrom I., Andersson A., Nyberg S., Ashbrook D., Purdy R.H., and Backstrom T. Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects. Neuroendocrinology 67 (1998) 126-138
64. Sundstrom I., Ashbrook D., and Backstrom T. Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study. Psychoneuroendocrinology 22 (1997) 25-38
65. Sundstrom I., Backstrom T., Wang M., Olsson T., Seippel L., and Bixo M. Premenstrual syndrome, neuroactive steroids and the brain. Gynecological Endocrinology 13 (1999) 206-220
66. Tiihonen J., Kuikka J., Rasanen P., Lepola U., Koponen H., Liuska A., Lehmusvaara A., Vainio P., Kononen M., Bergstrom K., Yu M., Kinnunen I., Akerman K., and Karhu J. Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysis. Molecular Psychiatry 2 (1997) 463-471
67. Walker M.C., and Semyanov A. Regulation of excitability by extrasynaptic GABA(A) receptors. Results and problems in cell differentiation. 44 29-48 (2008) 29-48
68. A receptors and their activation by GABA spillover in the mouse dentate gyrus. The Journal of Neuroscience 23 (2003) 10650-10661
69. Whiting P.J., Bonnert T.P., McKernan R.M., Farrar S., Le Bourdelles B., Heavens R.P., Smith D.W., Hewson L., Rigby M.R., Sirinathsinghji D.J.S., Thompson S.A., and Wafford K.A. Molecular and functional diversity of the expanding GABA-A receptor gene family. Molecular and Functional Diversity of Ion Channels and Receptors 868 (1999) 645-653
70. Wisden W., Laurie D.J., Monyer H., and Seeburg P.H. The distribution of 13-gaba-A receptor subunit messenger-Rnas in the rat-brain .1. telencephalon, diencephalon, mesencephalon. The Journal of Neuroscience 12 (1992) 1040-1062
71. Wisner K.L., Parry B.L., and Piontek C.M. Postpartum depression. New England Journal of Medicine 347 (2002) 194-199
72. Wohlfarth K.M., Bianchi M.T., and Macdonald R.L. Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit. The Journal of Neuroscience 22 (2002) 1541-1549