Interaction of macrolide antibiotics with intestinally expressed human and rat organic anion-transporting polypeptides

Drug Metabolism and Disposition

Volumn 37, Issue 12, 2009, Pages 2375-2382

  Lan, Tian ^a   Rao, Anuradha ^a   Haywood, Jamie ^a   Davis, Charles B ^b   Han, Chao ^b   Garver, Eric ^b   Dawson, Paul A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CLARITHROMYCIN; MACROLIDE; ORGANIC ANION TRANSPORTER 2; PROTEIN INHIBITOR; RIFAMYCIN; TAUROCHOLIC ACID;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; INHIBITION KINETICS; INTESTINE ABSORPTION; ISOTOPE LABELING; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; BIOLOGICAL TRANSPORT; CERCOPITHECUS AETHIOPS; CLARITHROMYCIN; COS CELLS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROMYCIN; ESTRONE; HUMANS; INTESTINES; KINETICS; MACROLIDES; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; RATS; TAUROCHOLIC ACID; TRANSFECTION;

RATTUS;

EID: 71049189272     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.028522     Document Type: Article

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