Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat

Drug Metabolism and Disposition

Volumn 36, Issue 12, 2008, Pages 2492-2498

  Garver, Eric ^a   Hugger, Erin D ^a   Shearn, Shawn P ^a   Rao, Anuradha ^b   Dawson, Paul A ^b   Davis, Charles B ^a   Han, Chao ^a  

^a GLAXOSMITHKLINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BUTYRIC ACID; CLARITHROMYCIN; FEXOFENADINE; GLYCOPROTEIN P; ORGANIC ANION TRANSPORTER; RIFAMYCIN; TAUROCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; DRUG TRANSPORT; DRUG UPTAKE; ENZYME INDUCTION; INTESTINE ABSORPTION; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIRHEUMATIC AGENTS; AREA UNDER CURVE; AZITHROMYCIN; BIOLOGICAL TRANSPORT, ACTIVE; CELL LINE; CLARITHROMYCIN; DOGS; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; INFUSIONS, INTRAVENOUS; INTESTINAL ABSORPTION; MALE; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; RATS; RATS, SPRAGUE-DAWLEY; RIFAMYCINS; TAUROCHOLIC ACID; TERFENADINE; TRANSFECTION;

RATTUS;

EID: 57349155622     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.022285     Document Type: Article

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