Urban particulate matter causes ER stress and the unfolded protein response in human lung cells

Toxicological Sciences

Volumn 112, Issue 1, 2009, Pages 111-122

  Watterson, Todd L ^a   Hamilton, Brett ^a   Martin, Randy ^b   Coulombe Jr , Roger A ^a  

^a UTAH STATE UNIVERSITY   (United States)

^b Utah State University   (United States)

Author keywords

C reactive protein; Calpain; Caspase 3; Caspase 9; Hsp27; Hsp90; Lipopolysaccharide; Particulate air pollution; PERK; PM10; Hsp70; PM2.5; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; C REACTIVE PROTEIN; CALPAIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN; PROTEIN KINASE; PROTEIN S6;

ARTICLE; CELL CULTURE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; PARTICULATE MATTER; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SECRETION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

AIR POLLUTANTS; BLOTTING, WESTERN; CELL LINE; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; HUMANS; LUNG; PARTICLE SIZE; PHOSPHORYLATION; PROTEIN DENATURATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; URBAN HEALTH;

EID: 71049178599     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp186     Document Type: Article

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