Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM2.5) and coarse particles (PM10-2.5) in outdoor and indoor air

Toxicology and Applied Pharmacology

Volumn 155, Issue 3, 1999, Pages 245-252

  Monn, Christian ^a   Becker, Susanne ^b  

^a ETH Zurich   (Switzerland)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Coarse particles; Endotoxin; Fine particles; IL 6; IL 8; Indoor air pollution; Lipopolysaccharide; Monocytes; Outdoor air pollution; PM10; PM2.5

Indexed keywords

CYTOKINE; ENDOTOXIN; INTERLEUKIN 6; INTERLEUKIN 8;

AIR POLLUTION; AMBIENT AIR; ARTICLE; CELL DEATH; CYTOTOXICITY; HOST RESISTANCE; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; MONOCYTE; SUSPENDED PARTICULATE MATTER; TARGET CELL; URBAN AREA;

EID: 0033559427     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8591     Document Type: Article

References (34)

1. Ackermann-Liebrich, U., Leuenberger, Ph., Schwartz, J., Schindler, Ch., Monn, Ch., Bolognini, G., Bougard, P., Brändli, O., Domienighetti, G., Elsasser, S., Grize, L., Karrer, W., Keller, R., Keller-Wossidlo, H., Künzli, N., Martin, B., Medici, T. C., Perrouchoud, A. P., Schöni, M. H., Tschopp, T. M., Villiger, B., Wuthrich, B., Zellweges, J. P., Zemp, E., and SAPALDIA Team (1997). Lung function and long term exposure to air pollutants in Switzerland. Am. J. Respir. Crit. Care Med. 155, 122-129.
2. Anderson, K., McSharry, C. P., Clark, C., Clark, C. J., Barclay, G. R., and Morris, G. P. (1996). Sump bay fever: Inhalational fever associated with a biologically contaminated water aerosol. Occup. Environ. Med. 53, 106-111.
3. Battarbee, J-L., Rose, N-L., and Long, X. (1997). A continuous, high resolution record of urban airborne particulates suitable for retrospective microscopical analysis. Atmos. Environ. 31, 171-181.
4. Becker, S., Soukup, J. M., Gilmour, M. I., and Devlin, R. B. (1996). Stimulation of human and rat alveolar macrophages by urban air particulates: Effects on oxidant radical generation and cytokine production. Toxicol. Appl. Pharmacol. 141, 637-648.
5. Bieszkiewicz, E., Boszczyk-Maleszak, H., Kaczorowska, B., and Mycielski, R. (1995). Isolation and identification of bacteria from activated sludge purifying petroleum wastewaters. Acta Microbiol. Pol. 44, 171-179.
6. Carter, J. D., Ghio, A., Samet, J. M., and Devlin, R. B. (1997). Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent. Toxicol. Appl. Phamacol. 146, 180-188.
7. Chen, L. C., Fine, J. M., Qu, Q. S., Amdur, M. O., and Gordon, T. (1992). Effects of fine and ultrafine sulfuric acid aerosols in guinea pigs: Alterations in alveolar macrophage function and intracellular pH. Toxicol. Appl. Pharmacol. 113, 109-117.
8. 10 source contributions in Rubidoux, CA. Atmos. Environ. 26, 693-706.
9. 10 aerosol in the Southern Californian Air Quality Study. Atmos. Environ. 28, 2061-2080.
10. Costa, D. L., and Dreher, K. L. (1997). Bioavailable transition metals in particulate matter mediate cardiopulmonay injury in healthy and compromised animal models. Environ. Health Perspect. 105(Suppl. 5), 1053-1060.
11. Dockery, D. W., Pope III, C. A., Xu, X., Spengler, J. D., Ware, J. H., Fay, M. E., Ferris, B. G., Jr., and Speizer, F. E. (1993). An association between air pollution and mortality in six U.S. cities. N. Engl. J. Med. 329, 1753-1759.
12. Dogra, S., and Donaldson, K. (1995). Effect of long and short fibre amosite asbestos on in vitro TNF production by rat alveolar macrophages: The modifying effect of lipopolysaccharide. Ind. Health 33, 131-141.
13. Donham, K. J., Reynolds, S. J., Whitten, P., Merchant, J. A., Burmeister, L., and Popendorf, W. J. (1995). Respiratory dysfunction in swine production facility workers: Dose-response relationships of environmental exposures and pulmonary function. Am. J. Ind. Med. 27, 405-418.
14. Douwes, J., and Heederick, D. (1997). Epidemiologic investigations of endotoxins. Int. J. Occup. Environ. Health 3, S26-S31.
15. Dreher, K., Jaskot, R., Kodavanti, U., Lehmann, J., Winselt, D., and Costa, D. (1996). Soluble transition metals mediate the acute pulmonary injury and airway hyperreactivity induced by residual oil fly ash articles. Chest 109, 33S-34S.
16. Fuzzi, S., Mandrioli, P., and Perfetto, A. (1997). Fog droplets - An atmospheric source of secondary biological aerosol particles. Atmos. Environ. 31, 287-290.
17. Hogquist, K. A., Unanue, E. R., and Chaplin, D. D. (1991). Release of IL-1 from mononuclear phagocytes. J. Immunol. 147, 2181-2186.
18. Holian, A., Kelley, K., and Hamilton, R. F., Jr. (1994). Mechanisms associated with human alveolar macrophage stimulation by particulates. Environ. Health Perspect. 10, 69-74.
19. Kodavanti, U. P., Jaskot, R. H., Su, W. Y., Costa, D. L., Ghio, A. J., and Dreher, K. L. (1997). Genetic variability in combustion particle-induced chronic lung injury. Am. J. Physiol. 272, L521-L532.
20. Kotloff, R. M., Little, J., and Elias, J. A. (1990). Human alveolar macrophage and blood monocyte interleukin-6 production. Am. J. Respir. Cell. Mol. Biol. 3(5), 497-505.
21. Mariani, S. M., Matiba, B., Armandola, E. A., and Krammer, P. H. (1997). Interleukin 1 beta-converting enzyme related proteases/caspases are involved in TRAIL-induced apoptosis of myeloma and leukemia cells. J. Cell Biol. 137, 221-229.
22. Myers, G. E. (1984). Survival of pathogenic bacteria in crude oil. J. Environ. Pathol. Toxicol. Oncol. 5, 79-87.
23. Pabst, M. J., and Johnston, R. B., Jr. (1980). Increased production of superoxide anion by macrophages exposed in vitro to muramyl dipeptide or lipopolysaccharide. J. Exp. Med. 151, 101-114.
24. Pritchard, R. J., Ghio, A. J. J., Lehmann, J. R., Winsett, D. W., Tepper, J. S., Park, P., Gilmour, M. I., Dreher, K. L., and Costa, D. L. (1996). Oxidant generation and lung injury after particulate air pollutants exposure increase with the concentrations of associated metals. Inhal. Toxicol. 8, 457-477.
25. Rylander, R. (1987). The role of endotoxin for reactions after exposure to cotton dust. Am. J. Ind. Med. 12, 687-697.
26. Rylander, R., and Haglind, P. (1984). Airborne endotoxins and humidifier disease. Clin. Allergy 14, 109-112.
27. Sandiford, T. J., Kunkel, S. L., Rolfe, M. W., Evanoff, H. L., Allen, R. M., and Strieter, R. M. (1992). Regulation of human alveolar macrophage- and blood monocyte-derived interleukin-8 by prostaglandin E2 and dexamethasone. J. Respir. Cell. Mol. Biol. 6(1), 75-81.
28. Schäppi, G. F., Monn, Ch., Wüthrich, B., Wanner, H.-U. (1996). Direct determination of allergens in ambient aerosols: Methodological aspects. Int. Arch. Allergy Immunol. 110, 364-370.
29. Schwartz, J. (1996). Air pollution and hospital admissions for respiratory disease. Epidemiology 7, 20-28.
30. Schwartz, J., Dockery, D. W., and Neas, L. M. (1996). Is daily mortality associated specifically with fine particles? J. Air Waste Manage. Assoc. 46, 927-937.
31. Someya, K., Tsutomi, Y., Soga, T., and Akahane, K. (1996). A lipid A analog inhibits LPS-induced cytokine expression and improves survival in endotoxemic mice. Immunopharmacol. Immunotoxicol. 18, 477-495.
32. Vrtala, S., Grote, M., Duchene, M., van Ree, Kraft, D., Scheiner, O., and Valenta, R. (1993). Properties of tree and grass pollen allergens: Reinvestigation of the linkage between solubility and allergenicity. Int. Arch. Allergy Immunol. 102(2), 160-169.
33. Wall, S. M., John, W., and Ondo, J. L. (1988). Measurement of aerosol size distributions for nitrate and major ionic species. Atmos. Environ. 22, 1649-1656.
34. Williams, D. R., and Halstead, B. W. (1982). Chelating agents in medicine. J. Toxicol. Clin. Toxicol. 19, 1081-1115.