Protective effect of N-glycan bisecting GlcNAc residues on β-amyloid production in Alzheimer's disease

Glycobiology

Volumn 20, Issue 1, 2010, Pages 99-106

  Akasaka Manya, Keiko ^a   Manya, Hiroshi ^a   Sakurai, Yoko ^a   Wojczyk, Boguslaw S ^b   Kozutsumi, Yasunori ^c   Saito, Yuko ^a   Taniguchi, Naoyuki ^d   Murayama, Shigeo ^a   Spitalnik, Steven L ^b   Endo, Tamao ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^c KYOTO UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Bisecting GlcNAc; N glycan

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; GLYCOSYLTRANSFERASE; MEMBRANE PROTEIN; MESSENGER RNA; N ACETYGLUCOSAMINE; N GLYCAN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; UPREGULATION;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CELL LINE, TUMOR; HUMANS; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; N-ACETYLGLUCOSAMINYLTRANSFERASES; POLYSACCHARIDES; RNA, MESSENGER; TIME FACTORS; UP-REGULATION;

EID: 70849108548     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwp152     Document Type: Article

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