β1,4-N-Acetylglucosaminyltransferase III potentiates β1 integrin-mediated neuritogenesis induced by serum deprivation in Neuro2a cells

Glycobiology

Volumn 16, Issue 6, 2006, Pages 564-571

  Shigeta, Masaki ^a   Shibukawa, Yukinao ^a   Ihara, Hideyuki ^a   Miyoshi, Eiji ^a   Taniguchi, Naoyuki ^a   Gu, Jianguo ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Bisecting GlcNAc; Glycosyltransferase; GnT III; Integrin; Neurite formation

Indexed keywords

BETA(1-4) N ACETYLGLUCOSAMINYLTRANSFERASE III; BETA1 INTEGRIN; F ACTIN; N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINYLTRANSFERASE; NERVE CELL ADHESION MOLECULE; PHYTOHEMAGGLUTININ; UNCLASSIFIED DRUG; BETA 1,4 MANNOSYL GLYCOPROTEIN BETA 1,4 N ACETYLGLUCOSAMINYLTRANSFERASE; BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE; ERYTHROAGGLUTININ, PLANT; POLYSACCHARIDE;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FLUORESCENCE ANALYSIS; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; NONHUMAN; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; TRANS GOLGI NETWORK; WESTERN BLOTTING; ANIMAL; CELL DIFFERENTIATION; CELL LINE; CULTURE MEDIUM; CYTOLOGY; GLYCOSYLATION; METABOLISM; NERVE CELL; NEURITE; PHYSIOLOGY; PROTEIN BINDING;

ANIMALIA;

ANIMALS; ANTIGENS, CD29; CELL DIFFERENTIATION; CELL LINE; CULTURE MEDIA, SERUM-FREE; GLYCOSYLATION; MICE; N-ACETYLGLUCOSAMINYLTRANSFERASES; NEURITES; NEURONS; PHYTOHEMAGGLUTININS; POLYSACCHARIDES; PROTEIN BINDING;

EID: 33646880044     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwj100     Document Type: Article

References (53)

1. Ahmari, S.E., Buchanan, J., and Smith, S.J. (2000) Assembly of presynaptic active zones from cytoplasmic transport packets. Nat. Neurosci., 3, 445-451.
2. Arcangeli, A., Becchetti, A., Mannini, A., Mugnai, G., De Filippi, P., Tarone, G., Del Bene, M.R., Barletta, E., Wanke, E., and Olivotto, M. (1993) Integrin-mediated neurite outgrowth in neuroblastoma cells depends on the activation of potassium channels. J. Cell Biol., 122, 1131-1143.
3. Barondes, S.H., Cooper, D.N., Gitt, M.A., and Leffler, H. (1994) Galectins. Structure and function of a large family of animal lectins. J. Biol. Chem., 269, 20807-20810.
4. Batistatou, A. and Greene, L.A. (1991) Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: Correlation with suppression of endonuclease activity. J. Cell. Biol., 115, 461-471.
5. Bellis, S.L. (2004) Variant glycosylation: An underappreciated regulatory mechanism for beta 1 integrins. Biochim. Biophys. Acta, 1663, 52-60.
6. Bhattacharyya, R., Bhaumik, M., Raju, T.S., and Stanley, P. (2002) Truncated, inactive N-acetylglucosaminyltransferase III (GlcNAc-TIII) induces neurological and other traits absent in mice that lack GlcNAc-TIII. J. Biol. Chem., 277, 26300-26309.
7. Bradley, P. and Berry, M. (1978) The Purkinje cell dendritic tree in mutant mouse cerebellum. A quantitative Golgi study of Weaver and Staggerer mice. Brain Res., 142, 135-141.
8. Cherubini, A., Hofmann, G., Pillozzi, S., Guasti, L., Crociani, O., Cilia, E., Di Stefano, P., Degani, S., Balzi, M., Olivotto, M., and others. (2005) Human ether-a-go-go-related gene 1 channels are physically linked to {beta}1 integrins and modulate adhesion-dependent signaling. Mol. Biol. Cell, 16, 2972-2983.
9. Cherubini, A., Pillozzi, S., Hofmann, G., Crociani, O., Guasti, L., Lastraioli, E., Polvani, S., Masi, A., Becchetti, A., Wanke, E., and others. (2002) HERG K+ channels and beta1 integrins interact through the assembly of a macromolecular complex. Ann. N. Y. Acad. Sci., 973, 559-561.
10. Cortes-Canteli, M., Pignatelli, M., Santos, A., and Perez-Castillo, A. (2002) CCAAT/enhancer-binding protein beta plays a regulatory role in differentiation and apoptosis of neuroblastoma cells. J. Biol. Chem., 277, 5460-5467.
11. Danen, E.H. and Yamada, K.M. (2001) Fibronectin, integrins, and growth control. J. Cell. Physiol., 189, 1-13.
12. Dotti, C.G., Sullivan, C.A., and Banker, G.A. (1988) The establishment of polarity by hippocampal neurons in culture. J. Neurosci., 8, 1454-1468.
13. Dwek, R.A. (1995) Glycobiology: "towards understanding the function of sugars". Biochem. Soc. Trans., 23, 1-25.
14. Giancotti, F.G. and Ruoslahti, E. (1999) Integrin signaling. Science, 285, 1028-1032.
15. Gu, J., Nishikawa, A., Tsuruoka, N., Ohno, M., Yamaguchi, N., Kangawa, K., and Taniguchi, N. (1993) Purification and characterization of UDP-N-acetylglucosamine: Alpha-6-D-mannoside beta 1-6N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase V) from a human lung cancer cell line. J. Biochem. (Tokyo), 113, 614-619.
16. Gu, J., and Taniguchi, N. (2004) Regulation of integrin functions by N-glycans. Glycoconj. J., 21, 9-15.
17. Gu, J., Zhao, Y., Isaji, T., Shibukawa, Y., Ihara, H., Takahashi, M., Ikeda, Y., Miyoshi, E., Honke, K., and Taniguchi, N. (2004) Beta1,4-N-Acetylglucosaminyltransferase III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells. Glycobiology, 14, 177-186.
18. Hynes, R.O. (1992) Integrins: Versatility, modulation, and signaling in cell adhesion. Cell, 69, 11-25.
19. Ihara, H., Ikeda, Y., Koyota, S., Endo, T., Honke, K., and Taniguchi, N. (2002) A catalytically inactive beta 1,4-N-acetylglucosaminyltransferase III (GnT-III) behaves as a dominant negative GnT-III inhibitor. Eur. J. Biochem., 269, 193-201.
20. Ihara, Y., Nishikawa, A., Tohma, T., Soejima, H., Niikawa, N., and Taniguchi, N. (1993) cDNA cloning, expression, and chromosomal localization of human N-acetylglucosaminyltransferase III (GnT-III). J. Biochem. (Tokyo), 113, 692-698.
21. Ihara, Y., Sakamoto, Y., Mihara, M., Shimizu, K., and Taniguchi, N. (1997) Overexpression of N-acetylglucosaminyltransferase III disrupts the tyrosine phosphorylation of Trk with resultant signaling dysfunction in PC12 cells treated with nerve growth factor. J. Biol. Chem., 272, 9629-9634.
22. Ikeda, Y., Koyota, S., Ihara, H., Yamaguchi, Y., Korekane, H., Tsuda, T., Sasai, K., and Taniguchi, N. (2000) Kinetic basis for the donor nucleotide-sugar specificity of beta1, 4-N-acetylglucosaminyltransferase III. J. Biochem. (Tokyo), 128, 609-619.
23. Isaji, T., Gu, J., Nishiuchi, R., Zhao, Y., Takahashi, M., Miyoshi, E., Honke, K., Sekiguchi, K., and Taniguchi, N. (2004) Introduction of bisecting GlcNAc into integrin alpha5beta1 reduces ligand binding and down-regulates cell adhesion and cell migration. J. Biol. Chem., 279, 19747-19754.
24. Ishii, T., Satoh, E., and Nishimura, M. (2001) Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells. J. Biol. Chem., 276, 42994-43003.
25. Kitamura, N., Ikekita, M., Hayakawa, S., Funahashi, H., and Furukawa, K. (2004) Suppression of proliferation and neurite extension of human neuroblastoma SH-SY5Y cells on immobilized Psathyrella velutina lectin. J. Neurosci. Res., 75, 384-390.
26. Kitamura, N., Ikekita, M., Sato, T., Akimoto, Y., Hatanaka, Y., Kawakami, H., Inomata, M., and Furukawa, K. (2005) Mouse Na+/K+-ATPase beta1-subunit has a K+-dependent cell adhesion activity for beta-GlcNAc-terminating glycans. Proc. Natl. Acad. Sci. U. S. A., 102, 2796-2801.
27. Koyota, S., Ikeda, Y., Miyagawa, S., Ihara, H., Koma, M., Honke, K., Shirakura, R., and Taniguchi, N. (2001) Down-regulation of the alpha-Gal epitope expression in N-glycans of swine endothelial cells by transfection with the N-acetylglucosaminyltransferase III gene. Modulation of the biosynthesis of terminal structures by a bisecting GlcNAc. J. Biol. Chem., 276, 32867-32874.
28. Kunkel, T.A. (1985) The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis. J. Biol. Chem., 260, 12866-12874.
29. Lopez-Maderuelo, M.D., Fernandez-Renart, M., Moratilla, C., and Renart, J. (2001) Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells. FEBS Lett., 490, 23-27.
30. Matta, S.G., Yorke, G., and Roisen, F.J. (1986) Neuritogenic and metabolic effects of individual gangliosides and their interaction with nerve growth factor in cultures of neuroblastoma and pheochromocytoma. Brain. Res., 392, 243-252.
31. Metzler, M., Gertz, A., Sarkar, M., Schachter, H., Schrader, J.W., and Marth, J.D. (1994) Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J., 13, 2056-2065.
32. Nakakita, S., Natsuka, S., Okamoto, J., Ikenaka, K., and Hase, S. (2005) Alteration of brain type N-glycans in neurological mutant mouse brain. J. Biochem. (Tokyo), 138, 277-283.
33. Nakayama, Y., Aoki, Y., and Niitsu, H. (2001) Studies on the mechanisms responsible for the formation of focal swellings on neuronal processes using a novel in vitro model of axonal injury. J. Neurotrauma, 18, 545-554.
34. Narasimhan, S. (1982) Control of glycoprotein synthesis. UDP-GlcNAc:gLycopeptide beta 4-N-acetylglucosaminyltransferase III, an enzyme in hen oviduct which adds GlcNAc in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-glycosyl oligosaccharides. J. Biol. Chem., 257, 10235-10242.
35. Nishikawa, A., Ihara, Y., Hatakeyama, M., Kangawa, K., and Taniguchi, N. (1992) Purification, cDNA cloning, and expression of UDP-N-acetylglucosamine: Beta-D-mannoside beta-1,4N-acetylglucosaminyltransferase III from rat kidney. J. Biol. Chem., 267, 18199-18204.
36. Sarner, S., Kozma, R., Ahmed, S., and Lim, L. (2000) Phosphatidylinositol 3-kinase, Cdc42, and Rac1 act downstream of Ras in integrin-dependent neurite outgrowth in N1E-115 neuroblastoma cells. Mol. Cell. Biol., 20, 158-172.
37. Saxon, E. and Bertozzi, C.R. (2001) Chemical and biological strategies for engineering cell surface glycosylation. Annu. Rev. Cell. Dev. Biol., 17, 1-23.
38. Schachter, H. (1986) Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides. Biochem. Cell. Biol., 64, 163-181.
39. Schwartz, M.A. and Assoian, R.K. (2001) Integrins and cell proliferation: Regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J. Cell. Sci., 114, 2553-2560.
40. Seko, A., Koketsu, M., Nishizono, M., Enoki, Y., Ibrahim, H.R., Juneja, L.R., Kim, M., and Yamamoto, T. (1997) Occurrence of a sialylglycopeptide and free sialylglycans in hen's egg yolk. Biochem. Biophys. Acta, 1335, 23-32.
41. Sheetz, M.P., Felsenfeld, D.P., and Galbraith, C.G. (1998) Cell migration: Regulation of force on extracellular-matrix-integrin complexes. Trends Cell. Biol., 8, 51-54.
42. Shimizu, H., Ochiai, K., Ikenaka, K., Mikoshiba, K., and Hase, S. (1993) Structures of N-linked sugar chains expressed mainly in mouse brain. J. Biochem. (Tokyo), 114, 334-338.
43. Sytnyk, V., Leshchyns'ka, I., Delling, M., Dityateva, G., Dityatev, A., and Schachter, M. (2002) Neural cell adhesion molecule promotes accumulation of TGN organelles at sites of neuron-to-neuron contacts. J. Cell. Biol., 159, 649-661.
44. Taniguchi, N., Nishikawa, A., Fujii, S., and Gu, J.G. (1989) Glycosyltransferase assays using pyridylaminated acceptors: N-acetylglucosaminyltransferase III, IV, and V. Methods Enzymol., 179, 397-408.
45. Turner, D.C., Flier, L.A., and Carbonetto, S. (1989) Identification of a cell-surface protein involved in PC12 cell-substratum adhesion and neurite outgrowth on laminin and collagen. J. Neurosci., 9, 3287-3296.
46. Varki, A. (1992) Selectins and other mammalian sialic acid-binding lectins. Curr. Opin. Cell Biol., 4, 257-266.
47. Varki, A. (1993) Biological roles of oligosaccharides: All of the theories are correct. Glycobiology, 3, 97-130.
48. Washbourne, P., Bennett, J.E., and McAllister, A.K. (2002) Rapid recruitment of NMDA receptor transport packets to nascent synapses. Nat. Neurosci., 5, 751-759.
49. Wu, G., Fang, Y., Lu, Z.H., and Ledeen, R.W. (1998) Induction of axon-like and dendrite-like processes in neuroblastoma cells. J. Neurocytol., 27, 1-14.
50. Xia, Z., Dickens, M., Raingeaud, J., Davis, R.J., and Greenberg, M.E. (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science, 270, 1326-1331.
51. Ye, Z. and Marth, J.D. (2004) N-glycan branching requirement in neuronal and postnatal viability. Glycobiology, 14, 547-558.
52. Yoshimura, M., Nishikawa, A., Ihara, Y., Taniguchi, S., and Taniguchi, N. (1995) Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection. Proc. Natl. Acad. Sci. USA, 92, 8754-8758.
53. Zhang, Z., Tarone, G., and Turner, D.C. (1993) Expression of integrin alpha 1 beta 1 is regulated by nerve growth factor and dexamethasone in PC12 cells. Functional consequences for adhesion and neurite outgrowth. J. Biol. Chem., 268, 5557-5565.