Altered expression of CYP in TSOD mice: A model of type 2 diabetes and obesity

Xenobiotica

Volumn 39, Issue 12, 2009, Pages 889-902

  Kudo, T ^a   Shimada, T ^b   Toda, T ^a   Igeta, S ^a   Suzuki, W ^b   Ikarashi, N ^a   Ochiai, W ^a   Ito, K ^a   Aburada, M ^b   Sugiyama, K ^a  

^a HOSHI UNIVERSITY   (Japan)

^b MUSASHINO UNIVERSITY   (Japan)

Author keywords

Cytochrome P450 (CYP) 3a; Diabetes; Peroxisome proliferator activated receptor gamma coactivator 1alpha (PGC 1alpha); TSOD (Tsumura; Suzuki; obese; diabetes) mice

Indexed keywords

CELL NUCLEUS RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 2C; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PREGNANE X RECEPTOR; TRIAZOLAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME METABOLISM; GENE EXPRESSION; LIVER; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PATHOPHYSIOLOGY; PHARMACOLOGICAL PARAMETERS; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; ISOENZYMES; LIVER; MALE; MICE; OBESITY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TIME FACTORS; TRIAZOLAM;

ANIMALIA; MUS;

EID: 70849087881     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498250903242592     Document Type: Article

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