Impairment of insulin-stimulated GLUT4 translocation in skeletal muscle and adipose tissue in the Tsumura Suzuki obese diabetic mouse: A new genetic animal model of type 2 diabetes

European Journal of Endocrinology

Volumn 145, Issue 6, 2001, Pages 785-790

  Miura, T ^a   Suzuki, W ^a   Ishihara, E ^a   Arai, I ^a   Ishida, H ^a   Seino, Y ^a   Tanigawa, K ^a  

^a SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; INSULIN;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL MEMBRANE; CONTROLLED STUDY; DISEASE SEVERITY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MALE; MICROSOME MEMBRANE; MOUSE; MOUSE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN TRANSPORT; SKELETAL MUSCLE; WESTERN BLOTTING;

EID: 0035206948     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1450785     Document Type: Article

References (24)

1. Glucose uptake and GLUT4 protein distribution in skeletal muscle of the obese Zucker rat
2. Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocation
3. Glucose transport: Locus of muscle insulin resistance in obese Zucker rats
4. A new mouse model of spontaneous diabetes derived from ddY strain
5. Genetic analysis of obese diabetes in the TSOD mouse
6. Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes
7. Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B GLUT4 translocation
8. Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance
9. Insulin signaling and glucose transport in insulin resistant skeletal muscle. Special reference to GLUT4 transgenic and GLUT4 knockout mice
10. Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase
11. Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats
12. A phosphotyrosyl mimetic peptide reverses impairment of insulin-stimulated translocation of GLUT4 caused by overexpression of PTP1B in rat adipose cells
13. Trafficking pathway of GLUT4 glucose transporters in muscle
14. Insulin action in skeletal muscle from patients with type 2 diabetes
15. Preservation of blood glucose analysis by glucose oxidase
16. Impaired glucose sensitivity of ATP-sensitive K+ channels in pancreatic B-cells in streptozotocin-induced type 2 diabetes rats
17. Glucosamine induces insulin resistance in vivo by affecting GLUT4 translocation in skeletal muscle. Implications for glucose toxicity
18. Insulin-stimulated glucose transporters in rat hindlimb muscles
19. Recruitment of GLUT4 glucose transporter by insulin in diabetic rat skeletal muscle
20. Insulin-stimulated translocation of glucose transporters in the isolated rat adipose cells: Characterization of subcellular fractions
21. Partial characterization of the glucose transport activity in the Golgirich fraction of fat cells
22. Molecular cloning and characterization of an insulin-regulatable glucose transporter
23. Increased liver glucose transporter protein and mRNA in streptozotocin-induced diabetic mice
24. A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact