Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 43, 2009, Pages 18131-18136

  Harris, Talia ^a   Eliyahu, Galit ^a   Frydman, Lucio ^a   Degani, Hadassa ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Breast cancer metabolism; Hyperpolarized NMR; Metabolic fluxes; Monocarboxylate transporters; Pyruvate lactate conversion

Indexed keywords

13C1 PYRUVATE; BIOLOGICAL MARKER; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1; PYRUVIC ACID DERIVATIVE; QUERCETIN; UNCLASSIFIED DRUG; CARBON; MONOCARBOXYLATE TRANSPORTER; PYRUVIC ACID;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; HUMAN; HUMAN CELL; KINETICS; METABOLISM; PERFUSION WEIGHTED IMAGING; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSPORT KINETICS; UPREGULATION; BREAST TUMOR; CELL HYPOXIA; CELL SURVIVAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; REPRODUCIBILITY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL CULTURE;

BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; CARBON ISOTOPES; CELL HYPOXIA; CELL SURVIVAL; HUMANS; KINETICS; LACTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MONOCARBOXYLIC ACID TRANSPORTERS; PYRUVIC ACID; QUERCETIN; REPRODUCIBILITY OF RESULTS; TUMOR CELLS, CULTURED;

EID: 70849085768     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909049106     Document Type: Article

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