Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  Comas, Iñaki ^a   Homolka, Susanne ^b   Niemann, Stefan ^b   Gagneux, Sebastien ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b RESEARCH CENTER BORSTEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ANALYTIC METHOD; ARTICLE; BACTERIAL STRAIN; CLUSTERED REGULATORY SHORT PALLINDROMIC REPEAT; CONTROLLED STUDY; CONVERGENT EVOLUTION; DNA SEQUENCE; GENE LOCUS; GENOTYPE; GOLD STANDARD; MULTILOCUS SEQUENCE TYPING; MYCOBACTERIUM INTERSPERSED REPETITIVE UNIT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHYLOGENETIC TREE; PHYLOGENY; SINGLE NUCLEOTIDE POLYMORPHISM; SPOLIGOTYPING; VARIABLE NUMBER OF TANDEM REPEAT; BACTERIUM IDENTIFICATION; CELL LINEAGE; DNA FINGERPRINTING; GENETIC MARKER; GENETICS; HUMAN; METABOLISM; METHODOLOGY; TRANSPOSON;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS COMPLEX;

BACTERIAL DNA;

BACTERIAL TYPING TECHNIQUES; CELL LINEAGE; DNA FINGERPRINTING; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; GENETIC MARKERS; GENOTYPE; HUMANS; MYCOBACTERIUM TUBERCULOSIS; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 70649084195     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007815     Document Type: Article

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