Evaluation of beta cell dysfunction by mixed meal tolerance test and oral l-arginine in patients with newly diagnosed type 2 diabetes mellitus

Experimental and Clinical Endocrinology and Diabetes

Volumn 117, Issue 10, 2009, Pages 573-576

  Ozbek, M ^a   Erdogan, M ^a   Karadeniz, M ^a   Cetinkalp, S ^a   Ozgen, A G ^a   Saygili, F ^a   Yilmaz, C ^a   Tuzun, M ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

L arginine; Mixed meal tolerance test; Type 2 diabetes

Indexed keywords

ARGININE; INSULIN;

ADULT; ARTICLE; CELL FUNCTION; CELL SECRETION; CLINICAL ARTICLE; FEMALE; FOOD INTAKE; HUMAN; INSULIN BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ADULT; ARGININE; DIABETES MELLITUS, TYPE 2; EATING; FEMALE; HUMANS; INSULIN; MALE; MIDDLE AGED; TIME FACTORS;

EID: 70450267509     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0029-1234087     Document Type: Article

References (28)

1. King H, Rewers M, WHO Ad Hoc Diabetes reporting Group. Global estimates for prevelance of diabetes mellitus and impaired glucose tolerance in adults. Diabetes Care 1993; 16: 157-177
2. Davies MJ, Rayman C, Gray IP et al. Insulin deficiency and increased plasma concentration of intact and 32/33 split proinsulin in subjects with impaired glucose tolerance. Diabet Med 1993; 10; 313-320
3. Hamman R. Genetic and enviromental determinants of non-insulindependent diabetes mellitus (NIDDM). Diabetes Metab Rev 1992; 8: 287-338 (Pubitemid 23171181)
4. Hypertension in Diabetes Sudy (HDS) I. Prevelance of hypertension in newly presenting type 2 diabetic patients and the association with risk factors for cardiovascular and diabetic complications. J hypertens 1993; 11:309-317
5. Hypertension in Diabetes Study (HDS) II Increased risk of cardiovascular complications in hypertensive type 2 diabetic patients. J Hypertens 1993; 11:319-325
6. Turner RC, Millns H, Neil HA et al. Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS: 23). BMJ 1998; 316: 823-828
7. Henry RR. Insulin resistance: From predisposing factor to therapeutic target in type 2 diabetes. Clin Ther 2003; 25 (suppl B): B47-B63
8. Ridker PM, Rijai N, Stampfer MJ et al. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 2000; 101: 1767-1772
9. Reaven GM. Pathophysiology of insulin resistance in human disease. Physiol Rev 1995; 75: 473-486
10. Henry RR. Type 2 Diabetes care. The role of insulin-sensitizing agents and practical implications for cardiovascular disease prevention. Am J Med 1998; 105 (1 A): S20-S26
11. Warran JH, Martin BC, Krolewski AS et al. Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic patients. Ann Intern Med 1990; 113: 909-915
12. O'Rahilly S. Science, medicine and the future. Non-insulin dependent diabetes mellitus: the gathering storm. BMJ 1997; 314: 955-959
13. Lillioja S, Mott DM, Howard BY et al. Impaired glucose tolerance as a disorder of insulin action. Longitudinal and cross-sectional studies in pima Indians. N Engl J Med 1988; 318: 1217-1225
14. Haffner SM, Stern MP, Dunn J et al. Diminished insulin sensitivity and increased insulin response in nonobese, nondiabetic mexican americans. Metabolism 1990; 39: 842-847 (Pubitemid 20250999)
15. Despres JP, Lamarche B, Mauriege P et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 1996; 334:952-957 (Pubitemid 26114161)
16. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237 (3): E214-E223
17. Toffolo G, De Grandi F, Cobelli C. Estimation of beta-cell sensitivity from intravenous glucose tolerance test C-peptide data. Knowledge of the kinetics avoids errors in modeling the secretion. Diabetes 1995; 44: 845-854
18. Piatti PM, Monti LD, Cauma A et al. The continuous low dose insulin and glucose infusion test: a simplified and accurate method for the evaluation of insulin sensitivity and insulin secretion in population studies. J Clin Endocrinol Metab 1995; 80 (1): 34-40
19. Rocic B, Lovrencic MV, Poje Metal. Effect of creatine on the pancreatic beta-cell. Exp Clin Endocrinol Diabetes 2007; 115 (1): 29-32
20. Aksoy DY, Yürekli PBS, Yildiz BO et al. Prevalence of glutamic acid decarboxylase antibody positivity and its association with insulin secretion and sensitivity in autoimmune thyroid disease: A pilot study. Exp Clin Endocrinol Diabetes 2006; 114 (8): 412-416
21. Hovorka R, Chassin L, Luzio SD et al. Pancreatic beta cell responsiveness during meal tolerance test: model assesment in normal subjects and subjects with newly diagnosed noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1998; 83: 744-750
22. Tharens B. Glucagon-like-peptide-1 and control of insulin secretion. Diabetes Metabolism 1995; 21: 311-318
23. Nauck MA, Hornberger E, Siegel EC et al. Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab 1986; 63: 492-498
24. Nauck MA, Bartels E, Orskov C et al. Additive insulinotropic effects of exogenous synthetic human gastric-inhibitory polypeptide and GLP-I (7-36) amide infused at near-physiological insulinotropic hormone and glucose contrentrations. J Clin Endocrinol Metab 1993; 76; 912-917
25. Blachier F, Mourtada A, Sener A et al. Stimulus-secretion coupling of arginine - induced insulin release uptake of metabolised and nonmetabolised cationic aminoacids by pancreatic islets. Endocrinology 1989; 124: 134-141 (Pubitemid 19033637)
26. Schmidt HHHW, Warner TD, Ishii K et al. Insulin secretion from pancreatic beta cells caused by 1-arginine-derived nitrogen oxides. Science 1992; 255;721-723
27. Marena S, Montegrosso G, De Michielli F et al. Comparison of the metabolic effects of mixed-meal and standart oral glucose tolerance test on glucose, insulin and c-peptide response in healthy, impaired glucose tolerance, mild and severe non-insulin dependent diabetic subjects. Acta Diabetol (abstract) 1992; 29 (1): 29-33
28. Katleen H, Zhidang I, Van S et al. Prolonged exposure of human beta cells to high glucose increases their release of proinsulin during acute stimulation with glucose or arginine. J Clin Endocrinol Metab 1999; 84: 386-390